JP2019195335A5 - - Google Patents
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- JP2019195335A5 JP2019195335A5 JP2019128863A JP2019128863A JP2019195335A5 JP 2019195335 A5 JP2019195335 A5 JP 2019195335A5 JP 2019128863 A JP2019128863 A JP 2019128863A JP 2019128863 A JP2019128863 A JP 2019128863A JP 2019195335 A5 JP2019195335 A5 JP 2019195335A5
- Authority
- JP
- Japan
- Prior art keywords
- acid sequence
- amino acid
- immunoglobulin
- nucleotide
- variable region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161450922P | 2011-03-09 | 2011-03-09 | |
| US61/450,922 | 2011-03-09 | ||
| US201161560006P | 2011-11-15 | 2011-11-15 | |
| US61/560,006 | 2011-11-15 | ||
| US201161566876P | 2011-12-05 | 2011-12-05 | |
| US61/566,876 | 2011-12-05 | ||
| US201261594729P | 2012-02-03 | 2012-02-03 | |
| US61/594,729 | 2012-02-03 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017175320A Division JP6557709B2 (ja) | 2011-03-09 | 2017-09-13 | モノクローナル抗体を作製するための方法および試薬 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019195335A JP2019195335A (ja) | 2019-11-14 |
| JP2019195335A5 true JP2019195335A5 (enExample) | 2019-12-26 |
Family
ID=45922811
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013557906A Active JP6211931B2 (ja) | 2011-03-09 | 2012-03-09 | モノクローナル抗体を作製するための方法および試薬 |
| JP2017175320A Expired - Fee Related JP6557709B2 (ja) | 2011-03-09 | 2017-09-13 | モノクローナル抗体を作製するための方法および試薬 |
| JP2019128863A Pending JP2019195335A (ja) | 2011-03-09 | 2019-07-11 | モノクローナル抗体を作製するための方法および試薬 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013557906A Active JP6211931B2 (ja) | 2011-03-09 | 2012-03-09 | モノクローナル抗体を作製するための方法および試薬 |
| JP2017175320A Expired - Fee Related JP6557709B2 (ja) | 2011-03-09 | 2017-09-13 | モノクローナル抗体を作製するための方法および試薬 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9920110B2 (enExample) |
| EP (2) | EP2683736B1 (enExample) |
| JP (3) | JP6211931B2 (enExample) |
| KR (3) | KR101938343B1 (enExample) |
| CN (2) | CN103842379A (enExample) |
| AU (3) | AU2012225310B2 (enExample) |
| CA (1) | CA2829606C (enExample) |
| DK (1) | DK2683736T3 (enExample) |
| ES (1) | ES2666301T3 (enExample) |
| HK (1) | HK1256304A1 (enExample) |
| HU (1) | HUE037095T2 (enExample) |
| WO (1) | WO2012122484A1 (enExample) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2387627E (pt) | 2009-01-15 | 2016-06-03 | Adaptive Biotechnologies Corp | Determinação do perfil de imunidade adaptativa e métodos de geração de anticorpos monoclonais |
| US9146241B2 (en) | 2011-11-23 | 2015-09-29 | Board Of Regents, The University Of Texas System | Proteomic identification of antibodies |
| JP6302847B2 (ja) | 2012-03-05 | 2018-03-28 | アダプティヴ バイオテクノロジーズ コーポレーション | 頻度が一致したサブユニットからの、対をなす免疫受容体鎖の決定 |
| ES2711156T3 (es) | 2012-05-08 | 2019-04-30 | Adaptive Biotechnologies Corp | Método para medir y calibrar el sesgo de amplificación en reacciones de PCR multiplexadas |
| US9708654B2 (en) | 2012-06-15 | 2017-07-18 | Board Of Regents, The University Of Texas System | High throughput sequencing of multiple transcripts |
| SG11201506991VA (en) * | 2013-03-15 | 2015-10-29 | Adaptive Biotechnologies Corp | Uniquely tagged rearranged adaptive immune receptor genes in a complex gene set |
| US9708657B2 (en) | 2013-07-01 | 2017-07-18 | Adaptive Biotechnologies Corp. | Method for generating clonotype profiles using sequence tags |
| US10208125B2 (en) | 2013-07-15 | 2019-02-19 | University of Pittsburgh—of the Commonwealth System of Higher Education | Anti-mucin 1 binding agents and uses thereof |
| CA2922372C (en) * | 2013-09-09 | 2018-05-15 | Shimadzu Corporation | Method for preparing peptide fragments, kit for preparing peptide fragments to be used therein, and analysis method |
| GB201316644D0 (en) * | 2013-09-19 | 2013-11-06 | Kymab Ltd | Expression vector production & High-Throughput cell screening |
| US10066265B2 (en) | 2014-04-01 | 2018-09-04 | Adaptive Biotechnologies Corp. | Determining antigen-specific t-cells |
| ES2777529T3 (es) | 2014-04-17 | 2020-08-05 | Adaptive Biotechnologies Corp | Cuantificación de genomas de células inmunitarias adaptativas en una mezcla compleja de células |
| EP3161166A4 (en) * | 2014-06-25 | 2017-11-29 | The Rockefeller University | Compositions and methods for rapid production of versatile nanobody repertoires |
| CN105277638A (zh) * | 2014-07-22 | 2016-01-27 | 沈鹤霄 | 一种单克隆抗体IgG质谱测序方法 |
| WO2016069886A1 (en) | 2014-10-29 | 2016-05-06 | Adaptive Biotechnologies Corporation | Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples |
| US10246701B2 (en) | 2014-11-14 | 2019-04-02 | Adaptive Biotechnologies Corp. | Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture |
| CN104560980B (zh) * | 2015-01-20 | 2017-04-05 | 中国人民解放军第三军医大学 | 基于高通量测序构建鼠BCR轻链Lamda文库的多重PCR引物和方法 |
| CN104560979B (zh) * | 2015-01-20 | 2017-04-05 | 中国人民解放军第三军医大学 | 基于高通量测序构建鼠bcr重链文库的多重pcr引物和方法 |
| WO2016138122A1 (en) | 2015-02-24 | 2016-09-01 | Adaptive Biotechnologies Corp. | Methods for diagnosing infectious disease and determining hla status using immune repertoire sequencing |
| US11139156B2 (en) | 2015-03-06 | 2021-10-05 | Micromass Uk Limited | In vivo endoscopic tissue identification tool |
| GB2556994B (en) | 2015-03-06 | 2021-05-12 | Micromass Ltd | Identification of bacterial strains in biological samples using mass spectrometry |
| GB2556436B (en) | 2015-03-06 | 2022-01-26 | Micromass Ltd | Cell population analysis |
| WO2016142691A1 (en) * | 2015-03-06 | 2016-09-15 | Micromass Uk Limited | Rapid evaporative ionisation mass spectrometry ("reims") and desorption electrospray ionisation mass spectrometry ("desi-ms") analysis of swabs and biopsy samples |
| US10777398B2 (en) | 2015-03-06 | 2020-09-15 | Micromass Uk Limited | Spectrometric analysis |
| WO2016142681A1 (en) | 2015-03-06 | 2016-09-15 | Micromass Uk Limited | Spectrometric analysis of microbes |
| EP3726562B1 (en) | 2015-03-06 | 2023-12-20 | Micromass UK Limited | Ambient ionization mass spectrometry imaging platform for direct mapping from bulk tissue |
| US10513733B2 (en) | 2015-03-23 | 2019-12-24 | Board Of Regents, The University Of Texas System | High throughout sequencing of paired VH and VL transcripts from B cells secreting antigen-specific antibodies |
| WO2016161273A1 (en) | 2015-04-01 | 2016-10-06 | Adaptive Biotechnologies Corp. | Method of identifying human compatible t cell receptors specific for an antigenic target |
| CN108348167B (zh) * | 2015-09-09 | 2022-06-03 | 普梭梅根公司 | 用于脑-颅面健康相关病症的源自微生物群系的诊断及治疗方法和系统 |
| WO2017178833A1 (en) | 2016-04-14 | 2017-10-19 | Micromass Uk Limited | Spectrometric analysis of plants |
| CN106047857B (zh) * | 2016-06-01 | 2020-04-03 | 苏州金唯智生物科技有限公司 | 一种发掘特异性功能抗体的方法 |
| CN107525934A (zh) * | 2016-06-21 | 2017-12-29 | 张效龙 | 一种测定血液中抗体氨基酸序列的方法 |
| US10428325B1 (en) | 2016-09-21 | 2019-10-01 | Adaptive Biotechnologies Corporation | Identification of antigen-specific B cell receptors |
| JP7473339B2 (ja) * | 2017-03-07 | 2024-04-23 | エフ． ホフマン－ラ ロシュ アーゲー | 代替の抗原特異的抗体変異体を発見するための方法 |
| JP2020527158A (ja) * | 2017-07-21 | 2020-09-03 | ノビミューン エスアー | 多重特異性抗体混合物の生成およびその使用方法 |
| CN109425662A (zh) * | 2017-08-23 | 2019-03-05 | 深圳华大基因研究院 | 一种鉴定蛋白的方法及系统 |
| WO2019084538A1 (en) | 2017-10-27 | 2019-05-02 | Board Of Regents, The University Of Texas System | TUMOR SPECIFIC ANTIBODIES, T CELL RECEPTORS AND METHODS OF IDENTIFICATION THEREOF |
| US11254980B1 (en) | 2017-11-29 | 2022-02-22 | Adaptive Biotechnologies Corporation | Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements |
| CN119881293A (zh) | 2018-03-21 | 2025-04-25 | 沃特世科技公司 | 基于非抗体高亲和力的样品制备、吸附剂、装置和方法 |
| CN108713136B (zh) * | 2018-03-29 | 2020-10-09 | 深圳达闼科技控股有限公司 | 物质检测方法、装置、电子设备及计算机可读存储介质 |
| CN108530533B (zh) * | 2018-04-13 | 2020-09-04 | 吉林大学 | 猪瘟病毒单克隆抗体hk24及医用用途 |
| US20220034902A1 (en) * | 2018-12-11 | 2022-02-03 | Merck Sharp & Dohme Corp. | Method for identifying high affinity monoclonal antibody heavy and light chain pairs from high throughput screens of b-cell and hybridoma libraries |
| EP3982369A4 (en) * | 2019-06-07 | 2023-06-14 | Chugai Seiyaku Kabushiki Kaisha | INFORMATION PROCESSING SYSTEM, INFORMATION PROCESSING PROCESS, PROGRAM AND METHOD FOR PRODUCTION OF AN ANTIGEN-BINDING MOLECULE OR PROTEIN |
| CN110452296A (zh) * | 2019-07-16 | 2019-11-15 | 福州精锐生物技术有限公司 | 一种兔单克隆抗体制备方法 |
| US12411141B2 (en) | 2019-09-16 | 2025-09-09 | Regeneron Pharmaceuticals, Inc. | LC-MS methods for antibody isotyping and quantification |
| CN115175919A (zh) * | 2019-12-09 | 2022-10-11 | 光行科技株式会社 | 转换结合剂、其制备方法、和各自使用该转换结合剂的药物组合物、测定试剂盒、以及抗原和抗体测定方法 |
| CN116457368A (zh) * | 2020-05-01 | 2023-07-18 | 匹兹堡大学联邦高等教育系统 | 用于鉴定纳米抗体和纳米抗体亲和力的组合物和方法 |
| CA3214755A1 (en) * | 2021-04-09 | 2022-10-13 | Natalie CASTELLANA | Method for antibody identification from protein mixtures |
| IT202100019334A1 (it) * | 2021-07-21 | 2023-01-21 | Univ Degli Studi Di Pavia | Metodo per l’identificazione dell’intera sequenza della regione variabile delle catene pesanti e leggere di immunoglobuline |
| CN115894687B (zh) * | 2022-03-31 | 2024-06-07 | 台州恩泽医疗中心(集团) | 一种抗hla-g1，-g2，-g5及hla-g6异构体分子的单克隆抗体及其用途 |
| CN116779037B (zh) * | 2022-07-27 | 2025-08-05 | 北京理工大学 | 一种基于从头测序和同源标签图论的抗体序列鉴定方法 |
| CN117849159B (zh) * | 2024-01-09 | 2025-01-07 | 融智生物科技（青岛）有限公司 | M蛋白的检测方法、电子设备及存储介质 |
| CN120214310B (zh) * | 2025-05-20 | 2025-08-19 | 中国农业大学 | 一种禽白血病抗原检测试剂盒及其制备方法 |
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-
2012
- 2012-03-09 WO PCT/US2012/028501 patent/WO2012122484A1/en not_active Ceased
- 2012-03-09 EP EP12711501.2A patent/EP2683736B1/en active Active
- 2012-03-09 HU HUE12711501A patent/HUE037095T2/hu unknown
- 2012-03-09 EP EP17196465.3A patent/EP3345922A1/en not_active Withdrawn
- 2012-03-09 CN CN201280021326.1A patent/CN103842379A/zh active Pending
- 2012-03-09 DK DK12711501.2T patent/DK2683736T3/en active
- 2012-03-09 CN CN201810154961.6A patent/CN108220297A/zh active Pending
- 2012-03-09 JP JP2013557906A patent/JP6211931B2/ja active Active
- 2012-03-09 ES ES12711501.2T patent/ES2666301T3/es active Active
- 2012-03-09 CA CA2829606A patent/CA2829606C/en active Active
- 2012-03-09 KR KR1020137026647A patent/KR101938343B1/ko active Active
- 2012-03-09 KR KR1020197026655A patent/KR20190107761A/ko not_active Ceased
- 2012-03-09 AU AU2012225310A patent/AU2012225310B2/en active Active
- 2012-03-09 KR KR1020197000660A patent/KR20190006083A/ko not_active Ceased
- 2012-03-09 US US13/416,582 patent/US9920110B2/en active Active
-
2017
- 2017-09-13 JP JP2017175320A patent/JP6557709B2/ja not_active Expired - Fee Related
- 2017-10-12 AU AU2017245395A patent/AU2017245395B2/en active Active
-
2018
- 2018-01-19 US US15/875,615 patent/US20190002532A1/en not_active Abandoned
- 2018-11-30 HK HK18115369.1A patent/HK1256304A1/en unknown
-
2019
- 2019-07-11 JP JP2019128863A patent/JP2019195335A/ja active Pending
- 2019-08-14 AU AU2019216660A patent/AU2019216660A1/en not_active Abandoned
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