JP2018535664A5 - - Google Patents
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- JP2018535664A5 JP2018535664A5 JP2018517631A JP2018517631A JP2018535664A5 JP 2018535664 A5 JP2018535664 A5 JP 2018535664A5 JP 2018517631 A JP2018517631 A JP 2018517631A JP 2018517631 A JP2018517631 A JP 2018517631A JP 2018535664 A5 JP2018535664 A5 JP 2018535664A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- polypeptide
- sequence identity
- dnase activity
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 229920001184 polypeptide Polymers 0.000 claims 299
- 102000004196 processed proteins & peptides Human genes 0.000 claims 299
- 108090000765 processed proteins & peptides Proteins 0.000 claims 299
- 102000016911 Deoxyribonucleases Human genes 0.000 claims 27
- 108010053770 Deoxyribonucleases Proteins 0.000 claims 27
- 230000000694 effects Effects 0.000 claims 27
- 108091005804 Peptidases Proteins 0.000 claims 11
- 239000004365 Protease Substances 0.000 claims 11
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 10
- 125000003275 alpha amino acid group Chemical group 0.000 claims 6
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 4
- 150000001413 amino acids Chemical class 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 3
- 230000037430 deletion Effects 0.000 claims 3
- 238000012217 deletion Methods 0.000 claims 3
- 238000006467 substitution reaction Methods 0.000 claims 3
- 102000013142 Amylases Human genes 0.000 claims 2
- 108010065511 Amylases Proteins 0.000 claims 2
- 102000004882 Lipase Human genes 0.000 claims 2
- 239000004367 Lipase Substances 0.000 claims 2
- 108090001060 Lipase Proteins 0.000 claims 2
- 235000019418 amylase Nutrition 0.000 claims 2
- 238000003780 insertion Methods 0.000 claims 2
- 230000037431 insertion Effects 0.000 claims 2
- 235000019421 lipase Nutrition 0.000 claims 2
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims 2
- 230000035772 mutation Effects 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 239000004382 Amylase Substances 0.000 claims 1
- 102220496643 Aryl hydrocarbon receptor nuclear translocator-like protein 1_S9E_mutation Human genes 0.000 claims 1
- 241000193744 Bacillus amyloliquefaciens Species 0.000 claims 1
- 102220584278 Cellular tumor antigen p53_G59D_mutation Human genes 0.000 claims 1
- 102220465972 Cilium assembly protein DZIP1_S24R_mutation Human genes 0.000 claims 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 239000004386 Erythritol Substances 0.000 claims 1
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 claims 1
- 102220574131 Heart- and neural crest derivatives-expressed protein 1_N74D_mutation Human genes 0.000 claims 1
- SQUHHTBVTRBESD-UHFFFAOYSA-N Hexa-Ac-myo-Inositol Natural products CC(=O)OC1C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O SQUHHTBVTRBESD-UHFFFAOYSA-N 0.000 claims 1
- 229930195725 Mannitol Natural products 0.000 claims 1
- 102220609673 Myocyte-specific enhancer factor 2A_S97G_mutation Human genes 0.000 claims 1
- 102000035195 Peptidases Human genes 0.000 claims 1
- 102220481291 Podocan_V66A_mutation Human genes 0.000 claims 1
- 239000002202 Polyethylene glycol Substances 0.000 claims 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 claims 1
- 102220485511 Rhodopsin_N60D_mutation Human genes 0.000 claims 1
- 102220528606 Ribonuclease P/MRP protein subunit POP5_S99D_mutation Human genes 0.000 claims 1
- 102220575589 Synaptotagmin-13_S97A_mutation Human genes 0.000 claims 1
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims 1
- 229940025131 amylases Drugs 0.000 claims 1
- 125000000129 anionic group Chemical group 0.000 claims 1
- 239000003945 anionic surfactant Substances 0.000 claims 1
- 102220350531 c.80A>G Human genes 0.000 claims 1
- 238000004140 cleaning Methods 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 239000003599 detergent Substances 0.000 claims 1
- 229940088598 enzyme Drugs 0.000 claims 1
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 claims 1
- 235000019414 erythritol Nutrition 0.000 claims 1
- 229940009714 erythritol Drugs 0.000 claims 1
- 230000001747 exhibiting effect Effects 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- FBPFZTCFMRRESA-GUCUJZIJSA-N galactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-GUCUJZIJSA-N 0.000 claims 1
- 239000008187 granular material Substances 0.000 claims 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 claims 1
- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 claims 1
- 229960000367 inositol Drugs 0.000 claims 1
- 239000000594 mannitol Substances 0.000 claims 1
- 235000010355 mannitol Nutrition 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 108010020132 microbial serine proteinases Proteins 0.000 claims 1
- 239000002736 nonionic surfactant Substances 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 229920005862 polyol Polymers 0.000 claims 1
- 150000003077 polyols Chemical class 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
- HEBKCHPVOIAQTA-ZXFHETKHSA-N ribitol Chemical compound OC[C@H](O)[C@H](O)[C@H](O)CO HEBKCHPVOIAQTA-ZXFHETKHSA-N 0.000 claims 1
- 102220243326 rs1183892581 Human genes 0.000 claims 1
- 102200115358 rs121918322 Human genes 0.000 claims 1
- 102220036452 rs137882485 Human genes 0.000 claims 1
- 102200065573 rs140660066 Human genes 0.000 claims 1
- 102220243297 rs374524755 Human genes 0.000 claims 1
- 102200001695 rs377767450 Human genes 0.000 claims 1
- 102220011740 rs386833408 Human genes 0.000 claims 1
- 102220036871 rs587780095 Human genes 0.000 claims 1
- 102220045610 rs587782243 Human genes 0.000 claims 1
- 102220276580 rs752209909 Human genes 0.000 claims 1
- 102220289974 rs757282628 Human genes 0.000 claims 1
- 102200085424 rs80358242 Human genes 0.000 claims 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 claims 1
- 239000000600 sorbitol Substances 0.000 claims 1
- 235000010356 sorbitol Nutrition 0.000 claims 1
- 150000005846 sugar alcohols Chemical class 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 238000005406 washing Methods 0.000 claims 1
- 239000000811 xylitol Substances 0.000 claims 1
- 235000010447 xylitol Nutrition 0.000 claims 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims 1
- 229960002675 xylitol Drugs 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023019160A JP7625024B2 (ja) | 2015-10-07 | 2023-02-10 | ポリペプチド |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA201500617 | 2015-10-07 | ||
| DKPA201500615 | 2015-10-07 | ||
| DKPA201500617 | 2015-10-07 | ||
| DKPA201500618 | 2015-10-07 | ||
| DKPA201500615 | 2015-10-07 | ||
| DKPA201500618 | 2015-10-07 | ||
| PCT/EP2016/074079 WO2017060475A2 (en) | 2015-10-07 | 2016-10-07 | Polypeptides |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023019160A Division JP7625024B2 (ja) | 2015-10-07 | 2023-02-10 | ポリペプチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018535664A JP2018535664A (ja) | 2018-12-06 |
| JP2018535664A5 true JP2018535664A5 (enExample) | 2019-11-21 |
| JP7540876B2 JP7540876B2 (ja) | 2024-08-27 |
Family
ID=58766438
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018517631A Active JP7540876B2 (ja) | 2015-10-07 | 2016-10-07 | ポリペプチド |
| JP2023019160A Active JP7625024B2 (ja) | 2015-10-07 | 2023-02-10 | ポリペプチド |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023019160A Active JP7625024B2 (ja) | 2015-10-07 | 2023-02-10 | ポリペプチド |
Country Status (9)
| Country | Link |
|---|---|
| US (11) | US10954497B2 (enExample) |
| EP (4) | EP3708660A3 (enExample) |
| JP (2) | JP7540876B2 (enExample) |
| CN (4) | CN116064474A (enExample) |
| BR (1) | BR112018007017B1 (enExample) |
| CA (1) | CA2994356A1 (enExample) |
| MX (1) | MX2018002831A (enExample) |
| WO (5) | WO2017060493A1 (enExample) |
| ZA (1) | ZA201802261B (enExample) |
Families Citing this family (118)
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| EP3708660A3 (en) | 2015-10-07 | 2020-12-30 | Novozymes A/S | Polypeptides |
| CN108884452A (zh) * | 2016-01-21 | 2018-11-23 | 诺维信公司 | 具有蛋白酶活性的多肽以及编码它们的多核苷酸 |
| PL3485010T3 (pl) | 2016-07-13 | 2025-01-27 | The Procter & Gamble Company | Warianty dnazy bacillus cibi i ich zastosowania |
| WO2018108865A1 (en) | 2016-12-12 | 2018-06-21 | Novozymes A/S | Use of polypeptides |
| WO2018177938A1 (en) | 2017-03-31 | 2018-10-04 | Novozymes A/S | Polypeptides having dnase activity |
| CA3058519A1 (en) | 2017-04-06 | 2018-10-11 | Novozymes A/S | Cleaning compositions comprosing a dnase and a protease |
| WO2018184818A1 (en) * | 2017-04-06 | 2018-10-11 | Novozymes A/S | Cleaning compositions and uses thereof |
| EP3607037A1 (en) * | 2017-04-06 | 2020-02-12 | Novozymes A/S | Cleaning compositions and uses thereof |
| MX2019011653A (es) * | 2017-04-06 | 2020-02-20 | Novozymes As | Composiciones detergentes y sus usos. |
| CN110709499A (zh) | 2017-04-06 | 2020-01-17 | 诺维信公司 | 清洁组合物及其用途 |
| US20200190438A1 (en) * | 2017-04-06 | 2020-06-18 | Novozymes A/S | Cleaning compositions and uses thereof |
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| WO2019057902A1 (en) * | 2017-09-22 | 2019-03-28 | Novozymes A/S | NEW POLYPEPTIDES |
| PL3476935T3 (pl) * | 2017-10-27 | 2022-03-28 | The Procter & Gamble Company | Kompozycje detergentowe zawierające odmiany polipeptydowe |
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| KR20220073769A (ko) * | 2019-09-29 | 2022-06-03 | 노보자임스 에이/에스 | 세제 조성물에서의 데옥시리보스뉴클레아제 용도 |
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| CN113234601B (zh) * | 2021-04-01 | 2023-04-25 | 新疆农业科学院微生物应用研究所(中国新疆—亚美尼亚生物工程研究开发中心) | 一株海洋真菌新种及其在植物抗干旱胁迫中的应用 |
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