|
US4269846A
(en)
|
1979-10-29 |
1981-05-26 |
Usv Pharmaceutical Corporation |
Heterocyclic compounds useful as anti-allergy agents
|
|
US5521184A
(en)
|
1992-04-03 |
1996-05-28 |
Ciba-Geigy Corporation |
Pyrimidine derivatives and processes for the preparation thereof
|
|
WO2000009495A1
(en)
|
1998-08-11 |
2000-02-24 |
Novartis Ag |
Isoquinoline derivatives with angiogenesis inhibiting activity
|
|
US6133031A
(en)
|
1999-08-19 |
2000-10-17 |
Isis Pharmaceuticals Inc. |
Antisense inhibition of focal adhesion kinase expression
|
|
GB9905075D0
(en)
|
1999-03-06 |
1999-04-28 |
Zeneca Ltd |
Chemical compounds
|
|
GB0004890D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
|
GB0011092D0
(en)
|
2000-05-08 |
2000-06-28 |
Black James Foundation |
Gastrin and cholecystokinin receptor ligands (III)
|
|
DE60105023T2
(de)
|
2000-06-28 |
2005-08-18 |
Smithkline Beecham P.L.C., Brentford |
Nassvermahlungsverfahren
|
|
MXPA04002243A
(es)
|
2001-09-19 |
2004-06-29 |
Aventis Pharma Sa |
Compuestos quimicos.
|
|
FR2831536A1
(fr)
|
2001-10-26 |
2003-05-02 |
Aventis Pharma Sa |
Nouveaux derives de benzimidazoles, leur procede de preparation, leur application a titre de medicament, compositions pharmaceutiques et nouvelle utilisation notamment comme inhibiteurs de kdr
|
|
MXPA04003954A
(es)
|
2001-10-26 |
2004-11-29 |
Aventis Pharma Inc |
Bencimidazoles.
|
|
CN101703509A
(zh)
|
2001-10-30 |
2010-05-12 |
诺瓦提斯公司 |
作为flt3受体酪氨酸激酶活性抑制剂的星形孢菌素衍生物
|
|
DE10207843A1
(de)
|
2002-02-15 |
2003-09-04 |
Schering Ag |
Mikrolia-Inhibitoren zur Unterbrechung von Interleukin 12 und IFN-gamma vermittelten Immunreaktionen
|
|
AR037647A1
(es)
|
2002-05-29 |
2004-12-01 |
Novartis Ag |
Derivados de diarilurea utiles para el tratamiento de enfermedades dependientes de la cinasa de proteina
|
|
GB0215676D0
(en)
|
2002-07-05 |
2002-08-14 |
Novartis Ag |
Organic compounds
|
|
TWI335913B
(en)
|
2002-11-15 |
2011-01-11 |
Vertex Pharma |
Diaminotriazoles useful as inhibitors of protein kinases
|
|
UA80767C2
(en)
|
2002-12-20 |
2007-10-25 |
Pfizer Prod Inc |
Pyrimidine derivatives for the treatment of abnormal cell growth
|
|
US7186832B2
(en)
|
2003-02-20 |
2007-03-06 |
Sugen Inc. |
Use of 8-amino-aryl-substituted imidazopyrazines as kinase inhibitors
|
|
US8524899B2
(en)
|
2003-03-04 |
2013-09-03 |
California Institute Of Technology |
Alternative heterocycles for DNA recognition
|
|
GB0305929D0
(en)
|
2003-03-14 |
2003-04-23 |
Novartis Ag |
Organic compounds
|
|
BRPI0413234A
(pt)
|
2003-08-01 |
2006-10-03 |
Genelabs Tech Inc |
derivados de imidazola bicìclica contra flaviviridae
|
|
AR045944A1
(es)
|
2003-09-24 |
2005-11-16 |
Novartis Ag |
Derivados de isoquinolina 1.4-disustituidas
|
|
WO2005118580A2
(en)
|
2004-05-12 |
2005-12-15 |
The Government Of The United States Of America As Represented By The Secretary, Department Of Health |
Tricyclic compounds as inhibitors of the hypoxic signaling pathway
|
|
BRPI0517887A
(pt)
|
2004-11-24 |
2008-10-21 |
Novartis Ag |
combinações de inibidores de jaks
|
|
CA2618370A1
(en)
|
2005-08-04 |
2007-02-15 |
Sirtris Pharmaceuticals, Inc. |
Oxazolopyridine derivatives as sirtuin modulators
|
|
US7709468B2
(en)
|
2005-09-02 |
2010-05-04 |
Abbott Laboratories |
Imidazo based heterocycles
|
|
ES2778846T3
(es)
|
2005-11-08 |
2020-08-12 |
Vertex Pharma |
Moduladores heterocíclicos de transportadores de casete de unión a ATP
|
|
TWI630207B
(zh)
|
2005-12-13 |
2018-07-21 |
英塞特控股公司 |
作為傑納斯激酶（ＪＡＮＵＳ ＫＩＮＡＳＥ）抑制劑之經雜芳基取代之吡咯并〔２，３-ｂ〕吡啶及吡咯并〔２，３-ｂ〕嘧啶
|
|
EP2044051B1
(en)
|
2006-06-22 |
2010-01-27 |
BIOVITRUM AB (publ) |
Pyridine and pyrazine derivatives as mnk kinase inhibitors
|
|
WO2009005551A2
(en)
|
2007-03-27 |
2009-01-08 |
Paratek Pharmaceuticals, Inc. |
Transcription factor modulating compounds and methods of use thereof
|
|
DE102007035333A1
(de)
|
2007-07-27 |
2009-01-29 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
GB0716292D0
(en)
|
2007-08-21 |
2007-09-26 |
Biofocus Dpi Ltd |
Imidazopyrazine compounds
|
|
WO2009079011A1
(en)
|
2007-12-19 |
2009-06-25 |
The Scripps Research Institute |
Benzimidazoles and analogs as rho kinase inhibitors
|
|
AP2010005308A0
(en)
|
2008-01-15 |
2010-06-30 |
Siga Technologies Inc |
Antiviral drugs for treatment of arenavirus infection
|
|
AR071523A1
(es)
|
2008-04-30 |
2010-06-23 |
Merck Serono Sa |
Compuestos biciclicos fusionados, un proceso para su preparacion, el compuesto para ser utilizado como medicamento en el tratamiento y profilaxis de enfermedades, una composicion farmaceutica y un conjunto que comprende paquetes separados del compuesto y de un ingrediente activo del medicamento
|
|
WO2009158118A2
(en)
|
2008-05-30 |
2009-12-30 |
University Of Notre Dame Du Lac |
Anti-bacterial agents from benzo[d]heterocyclic scaffolds for prevention and treatment of multidrug resistant bacteria
|
|
WO2010051245A1
(en)
|
2008-11-03 |
2010-05-06 |
Merck Sharp & Dohme Corp. |
Benzimidazole and aza-benzimidazole carboxamides
|
|
WO2010061903A1
(ja)
|
2008-11-27 |
2010-06-03 |
塩野義製薬株式会社 |
Pi3k阻害活性を有するピリミジン誘導体およびピリジン誘導体
|
|
GB0822981D0
(en)
|
2008-12-17 |
2009-01-21 |
Summit Corp Plc |
Compounds for treatment of duchenne muscular dystrophy
|
|
AU2010250055A1
(en)
|
2009-02-27 |
2011-09-15 |
Vertex Pharmaceuticals Incorporated |
Tri-cyclic pyrazolopyridine kinase inhibitors
|
|
AR076794A1
(es)
|
2009-05-22 |
2011-07-06 |
Incyte Corp |
Derivados de n-(hetero)aril-pirrolidina de pirazol-4-il-pirrolo [2,3-d]pirimidinas y pirrol-3-il-pirrolo [2,3-d ]pirimidinas como inhibidores de la quinasa janus y composiciones farmaceuticas que los contienen
|
|
EP2448938B9
(en)
|
2009-06-29 |
2015-06-10 |
Incyte Corporation |
Pyrimidinones as pi3k inhibitors
|
|
AR078012A1
(es)
|
2009-09-01 |
2011-10-05 |
Incyte Corp |
Derivados heterociclicos de las pirazol-4-il- pirrolo (2,3-d) pirimidinas como inhibidores de la quinasa janus
|
|
AR079529A1
(es)
|
2009-12-18 |
2012-02-01 |
Incyte Corp |
Derivados arilo y heteroarilo sustituidos y fundidos como inhibidores de la pi3k
|
|
WO2011075643A1
(en)
|
2009-12-18 |
2011-06-23 |
Incyte Corporation |
Substituted heteroaryl fused derivatives as pi3k inhibitors
|
|
WO2011099832A2
(en)
|
2010-02-12 |
2011-08-18 |
Crystalgenomics, Inc. |
Novel benzimidazole compound, preparation method thereof and pharmaceutical composition comprising the same
|
|
EP3050882B1
(en)
|
2010-03-10 |
2018-01-31 |
Incyte Holdings Corporation |
Piperidin-4-yl azetidine derivatives as jak1 inhibitors
|
|
EP2552208A4
(en)
|
2010-03-31 |
2014-07-09 |
Glaxo Group Ltd |
IMIDAZOLYL-IMIDAZOLES AS KINASE INHIBITORS
|
|
EP2558463A1
(en)
|
2010-04-14 |
2013-02-20 |
Incyte Corporation |
Fused derivatives as i3 inhibitors
|
|
EP2575866A4
(en)
|
2010-05-24 |
2013-10-16 |
Presidio Pharmaceuticals Inc |
HCV NS5A INHIBITORS
|
|
EP2627650A2
(en)
|
2010-05-26 |
2013-08-21 |
Merck Sharp & Dohme Corp. |
N-phenyl imidazole carboxamide inhibitors of 3-phosphoinositide-dependent protein kinase-1
|
|
US9062055B2
(en)
|
2010-06-21 |
2015-06-23 |
Incyte Corporation |
Fused pyrrole derivatives as PI3K inhibitors
|
|
CA2814688A1
(en)
|
2010-10-13 |
2012-04-19 |
Millennium Pharmaceuticals, Inc. |
Heteroaryls and uses thereof
|
|
CN103415515B
(zh)
|
2010-11-19 |
2015-08-26 |
因塞特公司 |
作为jak抑制剂的环丁基取代的吡咯并吡啶和吡咯并嘧啶衍生物
|
|
US9034884B2
(en)
|
2010-11-19 |
2015-05-19 |
Incyte Corporation |
Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as JAK inhibitors
|
|
EP2649062B1
(en)
|
2010-11-30 |
2015-04-08 |
Takeda Pharmaceutical Company Limited |
Bicyclic compounds as inhibitors of acetyl-coa carboxylase (acc)
|
|
TW201249844A
(en)
|
2010-12-20 |
2012-12-16 |
Incyte Corp |
N-(1-(substituted-phenyl)ethyl)-9H-purin-6-amines as PI3K inhibitors
|
|
WO2012125629A1
(en)
|
2011-03-14 |
2012-09-20 |
Incyte Corporation |
Substituted diamino-pyrimidine and diamino-pyridine derivatives as pi3k inhibitors
|
|
US8673905B2
(en)
|
2011-03-17 |
2014-03-18 |
Hoffmann-La Roche Inc. |
Imidazo pyrazines
|
|
US9126948B2
(en)
|
2011-03-25 |
2015-09-08 |
Incyte Holdings Corporation |
Pyrimidine-4,6-diamine derivatives as PI3K inhibitors
|
|
KR102104125B1
(ko)
*
|
2011-04-21 |
2020-05-29 |
재단법인 한국파스퇴르연구소 |
소염 화합물
|
|
WO2012170867A1
(en)
|
2011-06-09 |
2012-12-13 |
Rhizen Pharmaceuticals Sa |
Novel compounds as modulators of gpr-119
|
|
PE20140832A1
(es)
|
2011-06-20 |
2014-07-14 |
Incyte Corp |
Derivados de azetidinil fenil, piridil o pirazinil carboxamida como inhibidores de jak
|
|
TW201313721A
(zh)
|
2011-08-18 |
2013-04-01 |
Incyte Corp |
作為ｊａｋ抑制劑之環己基氮雜環丁烷衍生物
|
|
KR102030609B1
(ko)
|
2011-09-02 |
2019-10-11 |
인사이트 홀딩스 코포레이션 |
Ｐｉ３ｋ 억제제로서 헤테로시클릴아민
|
|
JP5854390B2
(ja)
|
2012-03-01 |
2016-02-09 |
学校法人兵庫医科大学 |
新規ベンズイミダゾール誘導体及びその用途
|
|
AR090548A1
(es)
|
2012-04-02 |
2014-11-19 |
Incyte Corp |
Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
|
|
US8940742B2
(en)
*
|
2012-04-10 |
2015-01-27 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
TW201406761A
(zh)
|
2012-05-18 |
2014-02-16 |
Incyte Corp |
做爲ｊａｋ抑制劑之哌啶基環丁基取代之吡咯并吡啶及吡咯并嘧啶衍生物
|
|
JP6217629B2
(ja)
|
2012-05-31 |
2017-10-25 |
住友化学株式会社 |
縮合複素環化合物
|
|
BR112015000675B1
(pt)
|
2012-07-13 |
2022-07-12 |
UCB Biopharma SRL |
Derivados de imidazopiridina como moduladores da atividade de tnf
|
|
AU2013337824B2
(en)
|
2012-11-01 |
2018-03-08 |
Incyte Holdings Corporation |
Tricyclic fused thiophene derivatives as JAK inhibitors
|
|
TWI736135B
(zh)
|
2013-03-01 |
2021-08-11 |
美商英塞特控股公司 |
吡唑并嘧啶衍生物治療PI3Kδ相關病症之用途
|
|
WO2014149207A2
(en)
|
2013-03-15 |
2014-09-25 |
Dow Agrosciences Llc |
Benzimidazole-based insecticidal compositions and related methods
|
|
EP2976077A4
(en)
|
2013-03-22 |
2016-11-30 |
Scripps Research Inst |
SUBSTITUTED BENZIMIDAZOLE AS NOCICEPTIN RECEPTOR MODULATORS
|
|
EP2994142A4
(en)
|
2013-05-08 |
2017-03-29 |
Colorado Seminary, Which Owns and Operates The University of Denver |
Antibiotic and anti-parasitic agents that modulate class ii fructose 1,6-bisphosphate aldolase
|
|
SMT202100040T1
(it)
|
2013-05-17 |
2021-03-15 |
Incyte Corp |
Derivati di bipirazolo come inibitori di jak
|
|
SG11201600108PA
(en)
|
2013-07-17 |
2016-02-26 |
Otsuka Pharma Co Ltd |
Cyanotriazole compounds
|
|
WO2015051241A1
(en)
*
|
2013-10-04 |
2015-04-09 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
KR20240153401A
(ko)
|
2014-04-08 |
2024-10-22 |
인사이트 홀딩스 코포레이션 |
Ｊａｋ 및 ｐｉ3ｋ 억제제 조합에 의한 ｂ-세포 악성종양의 치료
|
|
EP2930048A1
(en)
|
2014-04-10 |
2015-10-14 |
Johnson Controls Automotive Electronics SAS |
Head up display projecting visual information onto a screen
|
|
WO2015191677A1
(en)
|
2014-06-11 |
2015-12-17 |
Incyte Corporation |
Bicyclic heteroarylaminoalkyl phenyl derivatives as pi3k inhibitors
|
|
EA201790502A1
(ru)
|
2014-09-16 |
2017-10-31 |
Селджен Квонтисел Рисёрч, Инк. |
Ингибиторы гистоновых диметилаз
|
|
WO2016054491A1
(en)
*
|
2014-10-03 |
2016-04-07 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
MA40933A
(fr)
|
2014-11-11 |
2017-09-19 |
Piqur Therapeutics Ag |
Difluorométhyl-aminopyridines et difluorométhyl-aminopyrimidines
|
|
US9586949B2
(en)
|
2015-02-09 |
2017-03-07 |
Incyte Corporation |
Aza-heteroaryl compounds as PI3K-gamma inhibitors
|
|
EP4086259A1
(en)
|
2015-11-06 |
2022-11-09 |
Incyte Corporation |
Heterocyclic compounds as pi3k-gamma inhibitors
|
|
WO2017120194A1
(en)
|
2016-01-05 |
2017-07-13 |
Incyte Corporation |
Pyridine and pyridimine compounds as pi3k-gamma inhibitors
|
|
WO2017223414A1
(en)
|
2016-06-24 |
2017-12-28 |
Incyte Corporation |
HETEROCYCLIC COMPOUNDS AS PI3K-γ INHIBITORS
|