|
GB1219606A
(en)
|
1968-07-15 |
1971-01-20 |
Rech S Et D Applic Scient Soge |
Quinuclidinol derivatives and preparation thereof
|
|
LU88769I2
(fr)
|
1982-07-23 |
1996-11-05 |
Zeneca Ltd |
Bicalutamide et ses sels et esters pharmaceutiquement acceptables (Casodex (R))
|
|
US5093330A
(en)
|
1987-06-15 |
1992-03-03 |
Ciba-Geigy Corporation |
Staurosporine derivatives substituted at methylamino nitrogen
|
|
GB8916480D0
(en)
|
1989-07-19 |
1989-09-06 |
Glaxo Group Ltd |
Chemical process
|
|
GB8923590D0
(en)
|
1989-10-19 |
1989-12-06 |
Pfizer Ltd |
Antimuscarinic bronchodilators
|
|
US5395855A
(en)
|
1990-05-07 |
1995-03-07 |
Ciba-Geigy Corporation |
Hydrazones
|
|
PT100441A
(pt)
|
1991-05-02 |
1993-09-30 |
Smithkline Beecham Corp |
Pirrolidinonas, seu processo de preparacao, composicoes farmaceuticas que as contem e uso
|
|
US5451700A
(en)
|
1991-06-11 |
1995-09-19 |
Ciba-Geigy Corporation |
Amidino compounds, their manufacture and methods of treatment
|
|
NZ243082A
(en)
|
1991-06-28 |
1995-02-24 |
Ici Plc |
4-anilino-quinazoline derivatives; pharmaceutical compositions, preparatory processes, and use thereof
|
|
AU661533B2
(en)
|
1992-01-20 |
1995-07-27 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
JP3192424B2
(ja)
|
1992-04-02 |
2001-07-30 |
スミスクライン・ビーチャム・コーポレイション |
アレルギーまたは炎症疾患の治療用化合物
|
|
WO1993019751A1
(en)
|
1992-04-02 |
1993-10-14 |
Smithkline Beecham Corporation |
Compounds useful for treating inflammatory diseases and inhibiting production of tumor necrosis factor
|
|
SK279958B6
(sk)
|
1992-04-02 |
1999-06-11 |
Smithkline Beecham Corporation |
Zlúčeniny s protialergickým a protizápalovým účink
|
|
TW225528B
(enExample)
|
1992-04-03 |
1994-06-21 |
Ciba Geigy Ag |
|
|
ATE348110T1
(de)
|
1992-10-28 |
2007-01-15 |
Genentech Inc |
Hvegf rezeptor als vegf antagonist
|
|
GB9301000D0
(en)
|
1993-01-20 |
1993-03-10 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB9314893D0
(en)
|
1993-07-19 |
1993-09-01 |
Zeneca Ltd |
Quinazoline derivatives
|
|
GB9414193D0
(en)
|
1994-07-14 |
1994-08-31 |
Glaxo Group Ltd |
Compounds
|
|
GB9414208D0
(en)
|
1994-07-14 |
1994-08-31 |
Glaxo Group Ltd |
Compounds
|
|
ATE205483T1
(de)
|
1995-03-30 |
2001-09-15 |
Pfizer |
Chinazolinderivate
|
|
GB9508538D0
(en)
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivatives
|
|
US5747498A
(en)
|
1996-05-28 |
1998-05-05 |
Pfizer Inc. |
Alkynyl and azido-substituted 4-anilinoquinazolines
|
|
US5880141A
(en)
|
1995-06-07 |
1999-03-09 |
Sugen, Inc. |
Benzylidene-Z-indoline compounds for the treatment of disease
|
|
JP4146514B2
(ja)
|
1995-07-06 |
2008-09-10 |
ノバルティス アクチエンゲゼルシャフト |
ピロロピリミジン類およびその製造方法
|
|
US5760041A
(en)
|
1996-02-05 |
1998-06-02 |
American Cyanamid Company |
4-aminoquinazoline EGFR Inhibitors
|
|
GB9603095D0
(en)
|
1996-02-14 |
1996-04-10 |
Zeneca Ltd |
Quinazoline derivatives
|
|
ES2174250T5
(es)
|
1996-04-12 |
2010-04-21 |
Warner-Lambert Company Llc |
Inhibidores irreversibles de tirosina quinasas.
|
|
AU2912997A
(en)
|
1996-06-24 |
1998-01-14 |
Pfizer Inc. |
Phenylamino-substituted tricyclic derivatives for treatment of hyperproliferative diseases
|
|
DE19638745C2
(de)
|
1996-09-11 |
2001-05-10 |
Schering Ag |
Monoklonale Antikörper gegen die extrazelluläre Domäne des menschlichen VEGF - Rezeptorproteins (KDR)
|
|
WO1998010767A2
(en)
|
1996-09-13 |
1998-03-19 |
Sugen, Inc. |
Use of quinazoline derivatives for the manufacture of a medicament in the treatment of hyperproliferative skin disorders
|
|
EP0837063A1
(en)
|
1996-10-17 |
1998-04-22 |
Pfizer Inc. |
4-Aminoquinazoline derivatives
|
|
GB9622386D0
(en)
|
1996-10-28 |
1997-01-08 |
Sandoz Ltd |
Organic compounds
|
|
TW528755B
(en)
|
1996-12-24 |
2003-04-21 |
Glaxo Group Ltd |
2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
|
|
CO4950519A1
(es)
|
1997-02-13 |
2000-09-01 |
Novartis Ag |
Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
|
|
CO4940418A1
(es)
|
1997-07-18 |
2000-07-24 |
Novartis Ag |
Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso
|
|
US6166037A
(en)
|
1997-08-28 |
2000-12-26 |
Merck & Co., Inc. |
Pyrrolidine and piperidine modulators of chemokine receptor activity
|
|
AU9281298A
(en)
|
1997-10-01 |
1999-04-23 |
Kyowa Hakko Kogyo Co. Ltd. |
Benzodioxole derivatives
|
|
GB9721069D0
(en)
|
1997-10-03 |
1997-12-03 |
Pharmacia & Upjohn Spa |
Polymeric derivatives of camptothecin
|
|
GB9723590D0
(en)
|
1997-11-08 |
1998-01-07 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB9723566D0
(en)
|
1997-11-08 |
1998-01-07 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB9723589D0
(en)
|
1997-11-08 |
1998-01-07 |
Glaxo Group Ltd |
Chemical compounds
|
|
YU44900A
(sh)
|
1998-01-31 |
2003-01-31 |
Glaxo Group Limited |
Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola
|
|
CO4990969A1
(es)
|
1998-02-14 |
2000-12-26 |
Glaxo Group Ltd |
Derivados de 2-(purin-9-il)-tetrahidrofuran-3,4-diol
|
|
DE69910213T2
(de)
|
1998-06-23 |
2004-07-01 |
Glaxo Group Ltd., Greenford |
2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivate
|
|
GB9813540D0
(en)
|
1998-06-23 |
1998-08-19 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB9813565D0
(en)
|
1998-06-23 |
1998-08-19 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB9813535D0
(en)
|
1998-06-23 |
1998-08-19 |
Glaxo Group Ltd |
Chemical compounds
|
|
BR9815931A
(pt)
|
1998-06-30 |
2001-02-20 |
Dow Chemical Co |
Polióis poliméricos, um processo para sua produção, e espuma de poliuretanoobtida
|
|
ATE459616T1
(de)
|
1998-08-11 |
2010-03-15 |
Novartis Ag |
Isochinoline derivate mit angiogenesis-hemmender wirkung
|
|
ATE331726T1
(de)
|
1998-10-16 |
2006-07-15 |
Pfizer |
Adenine-derivate
|
|
GB9824579D0
(en)
|
1998-11-10 |
1999-01-06 |
Novartis Ag |
Organic compounds
|
|
UA71587C2
(uk)
|
1998-11-10 |
2004-12-15 |
Шерінг Акцієнгезелльшафт |
Аміди антранілової кислоти та їхнє застосування як лікарських засобів
|
|
DE69926536T3
(de)
|
1998-12-22 |
2013-09-12 |
Genentech, Inc. |
Antagonisten von vaskular-endothelialen zellwachstumsfaktoren und ihre anwendung
|
|
CA2366857C
(en)
|
1999-03-30 |
2010-12-14 |
Novartis Ag |
Phthalazine derivatives for treating inflammatory diseases
|
|
GB9913083D0
(en)
|
1999-06-04 |
1999-08-04 |
Novartis Ag |
Organic compounds
|
|
PT1175402E
(pt)
|
1999-05-04 |
2005-11-30 |
Schering Corp |
Derivados da piperidina uteis como antagonistas ccr5
|
|
CA2371583C
(en)
|
1999-05-04 |
2005-09-13 |
Schering Corporation |
Piperazine derivatives useful as ccr5 antagonists
|
|
YU25500A
(sh)
|
1999-05-11 |
2003-08-29 |
Pfizer Products Inc. |
Postupak za sintezu analoga nukleozida
|
|
GB9913932D0
(en)
|
1999-06-15 |
1999-08-18 |
Pfizer Ltd |
Purine derivatives
|
|
US6322771B1
(en)
|
1999-06-18 |
2001-11-27 |
University Of Virginia Patent Foundation |
Induction of pharmacological stress with adenosine receptor agonists
|
|
ES2165768B1
(es)
|
1999-07-14 |
2003-04-01 |
Almirall Prodesfarma Sa |
Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
|
|
HU229439B1
(hu)
|
1999-08-21 |
2013-12-30 |
Takeda Gmbh |
Roflumilast és salmeterol szinergetikus kombinációja
|
|
CO5180581A1
(es)
|
1999-09-30 |
2002-07-30 |
Pfizer Prod Inc |
Compuestos para el tratamiento de la isquemia ciones farmaceuticas que los contienen para el tratamiento de la isquemia
|
|
GB9924361D0
(en)
|
1999-10-14 |
1999-12-15 |
Pfizer Ltd |
Purine derivatives
|
|
GB9924363D0
(en)
|
1999-10-14 |
1999-12-15 |
Pfizer Central Res |
Purine derivatives
|
|
GB0003960D0
(en)
|
2000-02-18 |
2000-04-12 |
Pfizer Ltd |
Purine derivatives
|
|
TWI227240B
(en)
|
2000-06-06 |
2005-02-01 |
Pfizer |
2-aminocarbonyl-9H-purine derivatives
|
|
GB0015727D0
(en)
|
2000-06-27 |
2000-08-16 |
Pfizer Ltd |
Purine derivatives
|
|
IL153707A0
(en)
|
2000-06-27 |
2003-07-06 |
S A L V A T Lab Sa |
Carbamates derived from arylalkylamines
|
|
GB0015876D0
(en)
|
2000-06-28 |
2000-08-23 |
Novartis Ag |
Organic compounds
|
|
DE10038639A1
(de)
|
2000-07-28 |
2002-02-21 |
Schering Ag |
Nichtsteroidale Entzündungshemmer
|
|
CZ304043B6
(cs)
|
2000-08-05 |
2013-09-04 |
Glaxo Group Limited |
Estery steroidních thiokyselin
|
|
PE20020354A1
(es)
|
2000-09-01 |
2002-06-12 |
Novartis Ag |
Compuestos de hidroxamato como inhibidores de histona-desacetilasa (hda)
|
|
GB0022695D0
(en)
|
2000-09-15 |
2000-11-01 |
Pfizer Ltd |
Purine Derivatives
|
|
GB0028383D0
(en)
|
2000-11-21 |
2001-01-03 |
Novartis Ag |
Organic compounds
|
|
AU2002228015B2
(en)
|
2000-12-22 |
2007-08-23 |
Almirall, S.A. |
Quinuclidine carbamate derivatives and their use as M3 antagonists
|
|
CA2433128C
(en)
|
2000-12-28 |
2010-05-25 |
Almirall Prodesfarma Ag |
Novel quinuclidine derivatives and medicinal compositions containing the same
|
|
EP1241176A1
(en)
|
2001-03-16 |
2002-09-18 |
Pfizer Products Inc. |
Purine derivatives for the treatment of ischemia
|
|
US7291608B2
(en)
|
2001-04-30 |
2007-11-06 |
Glaxo Group Limited |
Anti-inflammatory 17.β.-carbothioate ester derivatives of androstane with a cyclic ester group in position 17.α
|
|
AR035885A1
(es)
|
2001-05-14 |
2004-07-21 |
Novartis Ag |
Derivados de 4-amino-5-fenil-7-ciclobutilpirrolo (2,3-d)pirimidina, un proceso para su preparacion, una composicion farmaceutica y el uso de dichos derivados para la preparacion de una composicion farmaceutica
|
|
BR0209986A
(pt)
|
2001-05-25 |
2004-04-06 |
Pfizer |
Agonista de a2a em combinação com um agente anticolinérgico, para o tratamento de doenças obstrutivas das vias respiratórias
|
|
ES2307751T3
(es)
|
2001-06-12 |
2008-12-01 |
Glaxo Group Limited |
Nuevos esteres heterociclicos centi-inflamatorios 17 alfa de derivados 17 beta de carbotioato de androstano.
|
|
DK2327765T3
(en)
|
2001-06-21 |
2015-07-13 |
Basf Enzymes Llc |
nitrilases
|
|
GB0119249D0
(en)
|
2001-08-07 |
2001-10-03 |
Novartis Ag |
Organic compounds
|
|
HUP0401849A3
(en)
|
2001-10-17 |
2007-05-02 |
Ucb Sa |
Quinuclidine derivatives, processes for preparing them and their uses as m2 and/or m3 muscarinic receptor inhibitors
|
|
GB0125259D0
(en)
|
2001-10-20 |
2001-12-12 |
Glaxo Group Ltd |
Novel compounds
|
|
MY130622A
(en)
|
2001-11-05 |
2007-07-31 |
Novartis Ag |
Naphthyridine derivatives, their preparation and their use as phosphodiesterase isoenzyme 4 (pde4) inhibitors
|
|
WO2003048181A1
(en)
|
2001-12-01 |
2003-06-12 |
Glaxo Group Limited |
17.alpha. -cyclic esters of 16-methylpregnan-3,20-dione as anti-inflammatory agents
|
|
EA006505B1
(ru)
|
2001-12-20 |
2005-12-29 |
Лабораториос С.А.Л.В.А.Т.,С.А. |
Производные карбамата 1-алкил-1-азониабицикло[2.2.2]октана и их применение в качестве антагонистов мускаринового рецептора
|
|
WO2003072592A1
(en)
|
2002-01-15 |
2003-09-04 |
Glaxo Group Limited |
17.alpha-cycloalkyl/cycloylkenyl esters of alkyl-or haloalkyl-androst-4-en-3-on-11.beta.,17.alpha.-diol 17.beta.-carboxylates as anti-inflammatory agents
|
|
AU2003201693A1
(en)
|
2002-01-21 |
2003-09-02 |
Glaxo Group Limited |
Non-aromatic 17.alpha.-esters of androstane-17.beta.-carboxylate esters as anti-inflammatory agents
|
|
GB0202216D0
(en)
|
2002-01-31 |
2002-03-20 |
Glaxo Group Ltd |
Novel compounds
|
|
WO2003082787A1
(en)
|
2002-03-26 |
2003-10-09 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
|
|
EA008830B1
(ru)
|
2002-03-26 |
2007-08-31 |
Бёрингер Ингельхайм Фармасьютиклз, Инк. |
Миметики глюкокортикоидов, способы их получения, фармацевтические композиции и их применение
|
|
WO2003086408A1
(en)
|
2002-04-10 |
2003-10-23 |
University Of Virginia Patent Foundation |
Use of a2a adenosine receptor agonists for the treatment of inflammatory diseases
|
|
ES2206021B1
(es)
|
2002-04-16 |
2005-08-01 |
Almirall Prodesfarma, S.A. |
Nuevos derivados de pirrolidinio.
|
|
ES2201907B1
(es)
|
2002-05-29 |
2005-06-01 |
Almirall Prodesfarma, S.A. |
Nuevos derivados de indolilpiperidina como potentes agentes antihistaminicos y antialergicos.
|
|
DE10224888A1
(de)
|
2002-06-05 |
2003-12-24 |
Merck Patent Gmbh |
Pyridazinderivate
|
|
US7074806B2
(en)
|
2002-06-06 |
2006-07-11 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
|
|
DE10225574A1
(de)
|
2002-06-10 |
2003-12-18 |
Merck Patent Gmbh |
Aryloxime
|
|
DE10227269A1
(de)
|
2002-06-19 |
2004-01-08 |
Merck Patent Gmbh |
Thiazolderivate
|
|
WO2004000814A1
(en)
|
2002-06-25 |
2003-12-31 |
Merck Frosst Canada & Co. |
8-(biaryl) quinoline pde4 inhibitors
|
|
US20060004056A1
(en)
|
2002-07-02 |
2006-01-05 |
Bernard Cote |
Di-aryl-substituted-ethan pyridone pde4 inhibitors
|
|
ES2204295B1
(es)
|
2002-07-02 |
2005-08-01 |
Almirall Prodesfarma, S.A. |
Nuevos derivados de quinuclidina-amida.
|
|
DK1521733T3
(da)
|
2002-07-08 |
2014-10-13 |
Pfizer Prod Inc |
Modulatorer af glucocorticoid receptoren
|
|
AR040962A1
(es)
|
2002-08-09 |
2005-04-27 |
Novartis Ag |
Compuestos derivados de tiazol 1,3-2-ona, composicion farmaceutica y proceso de preparacion del compuesto
|
|
AU2003260371A1
(en)
|
2002-08-10 |
2004-03-11 |
Altana Pharma Ag |
Piperidine-n-oxide-derivatives
|
|
WO2004018457A1
(en)
|
2002-08-10 |
2004-03-04 |
Altana Pharma Ag |
Pyrrolidinedione substituted piperidine-phthalazones as pde4 inhibitors
|
|
JP2005538138A
(ja)
|
2002-08-10 |
2005-12-15 |
アルタナ ファルマ アクチエンゲゼルシャフト |
Pde4インヒビターとしてのピリダジノン誘導体
|
|
AU2003255376A1
(en)
|
2002-08-10 |
2004-03-11 |
Altana Pharma Ag |
Piperidine-derivatives as pde4 inhibitors
|
|
WO2004018431A2
(en)
|
2002-08-17 |
2004-03-04 |
Altana Pharma Ag |
Novel phenanthridines
|
|
JP2005537313A
(ja)
|
2002-08-17 |
2005-12-08 |
アルタナ ファルマ アクチエンゲゼルシャフト |
新規のベンゾナフチリジン
|
|
SE0202483D0
(sv)
|
2002-08-21 |
2002-08-21 |
Astrazeneca Ab |
Chemical compounds
|
|
DE60231341D1
(de)
|
2002-08-23 |
2009-04-09 |
Ranbaxy Lab Ltd |
Fluor- und sulfonylaminohaltige, 3,6-disubstituierptorantagonisten
|
|
WO2004019944A1
(en)
|
2002-08-29 |
2004-03-11 |
Altana Pharma Ag |
2-hydroxy-6-phenylphenanthridines as pde-4 inhibitors
|
|
ES2281658T3
(es)
|
2002-08-29 |
2007-10-01 |
Nycomed Gmbh |
3-hidroxi-6-fenilfenantridinas como inhibidores de pde-4.
|
|
JP2006096662A
(ja)
|
2002-09-18 |
2006-04-13 |
Sumitomo Pharmaceut Co Ltd |
新規6−置換ウラシル誘導体及びアレルギー性疾患の治療剤
|
|
CA2497903A1
(en)
|
2002-09-18 |
2004-04-01 |
Ono Pharmaceutical Co., Ltd. |
Triazaspiro[5.5]undecane derivatives and drugs comprising the same as the active ingredient
|
|
JP2004107299A
(ja)
|
2002-09-20 |
2004-04-08 |
Japan Energy Corp |
新規1−置換ウラシル誘導体及びアレルギー性疾患の治療剤
|
|
DE10246374A1
(de)
|
2002-10-04 |
2004-04-15 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Betamimetika mit verlängerter Wirkungsdauer, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
|
|
DE60317918T2
(de)
|
2002-10-23 |
2009-01-29 |
Glenmark Pharmaceuticals Ltd. |
Tricyclische verbindungen zur behandlung von entzündlichen und allergischen erkrankungen verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen
|
|
GB0225535D0
(en)
|
2002-11-01 |
2002-12-11 |
Glaxo Group Ltd |
Medicinal compounds
|
|
GB0225540D0
(en)
|
2002-11-01 |
2002-12-11 |
Glaxo Group Ltd |
Medicinal compounds
|
|
DE10253426B4
(de)
|
2002-11-15 |
2005-09-22 |
Elbion Ag |
Neue Hydroxyindole, deren Verwendung als Inhibitoren der Phosphodiesterase 4 und Verfahren zu deren Herstellung
|
|
DE10253282A1
(de)
|
2002-11-15 |
2004-05-27 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Arzneimittel zur Behandlung von chronisch obstruktiver Lungenerkrankung
|
|
DE10253220A1
(de)
|
2002-11-15 |
2004-05-27 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Dihydroxy-Methyl-Phenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
|
|
AU2007347115A1
(en)
*
|
2006-04-04 |
2008-10-23 |
The Regents Of The University Of California |
PI3 kinase antagonists
|
|
MX2009005144A
(es)
|
2006-11-22 |
2009-05-27 |
Incyte Corp |
Imidazotriazinas e imidazopirimidinas como inhibidores de cinasa.
|
|
NZ602791A
(en)
|
2008-05-21 |
2014-04-30 |
Incyte Corp |
Salts of 2-fluoro-n-methyl-4-[7-(quinolin-6-yl-methyl)- imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide and processes related to preparing the same
|
|
ES2894830T3
(es)
*
|
2012-04-03 |
2022-02-16 |
Novartis Ag |
Productos combinados con inhibidores de tirosina·cinasa y su uso
|
|
JP2015512447A
(ja)
*
|
2012-04-03 |
2015-04-27 |
ノバルティス アーゲー |
チロシンキナーゼ阻害薬の組合せおよびその使用
|
|
JO3300B1
(ar)
*
|
2012-06-06 |
2018-09-16 |
Novartis Ag |
مركبات وتركيبات لتعديل نشاط egfr
|
|
KR101418970B1
(ko)
*
|
2013-03-20 |
2014-07-11 |
(주)제욱 |
야생형 EGFR를 가진 비소세포폐암에서 EGFR 억제제와 c-MET 억제제 병용투여에 대한 반응 예측 인자
|
|
WO2015083059A1
(en)
|
2013-12-02 |
2015-06-11 |
Novartis Ag |
Forms of the egfr inhibitor
|