JP2017510580A5 - - Google Patents
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- Publication number
- JP2017510580A5 JP2017510580A5 JP2016558569A JP2016558569A JP2017510580A5 JP 2017510580 A5 JP2017510580 A5 JP 2017510580A5 JP 2016558569 A JP2016558569 A JP 2016558569A JP 2016558569 A JP2016558569 A JP 2016558569A JP 2017510580 A5 JP2017510580 A5 JP 2017510580A5
- Authority
- JP
- Japan
- Prior art keywords
- genus
- oxo
- amino
- morganella
- citrobacter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 201000009906 Meningitis Diseases 0.000 claims description 6
- 241000588771 Morganella <proteobacterium> Species 0.000 claims description 6
- 241000589291 Acinetobacter Species 0.000 claims description 5
- 241001453380 Burkholderia Species 0.000 claims description 5
- 241000588923 Citrobacter Species 0.000 claims description 5
- 241000588914 Enterobacter Species 0.000 claims description 5
- 241000588722 Escherichia Species 0.000 claims description 5
- 241000588748 Klebsiella Species 0.000 claims description 5
- 241000588653 Neisseria Species 0.000 claims description 5
- 241000588769 Proteus <enterobacteria> Species 0.000 claims description 5
- 241000589516 Pseudomonas Species 0.000 claims description 5
- 241000607142 Salmonella Species 0.000 claims description 5
- 241000607720 Serratia Species 0.000 claims description 5
- 150000001875 compounds Chemical class 0.000 claims description 5
- 241000606125 Bacteroides Species 0.000 claims description 3
- 241000589876 Campylobacter Species 0.000 claims description 3
- 241000122971 Stenotrophomonas Species 0.000 claims description 3
- 239000008194 pharmaceutical composition Substances 0.000 claims description 3
- 241000894007 species Species 0.000 claims description 3
- 208000035143 Bacterial infection Diseases 0.000 claims description 2
- 230000001580 bacterial effect Effects 0.000 claims description 2
- 208000022362 bacterial infectious disease Diseases 0.000 claims description 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 4
- YMGUBTXCNDTFJI-UHFFFAOYSA-N cyclopropanecarboxylic acid Chemical compound OC(=O)C1CC1 YMGUBTXCNDTFJI-UHFFFAOYSA-N 0.000 claims 2
- 125000000219 ethylidene group Chemical group [H]C(=[*])C([H])([H])[H] 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- -1 2-aminothiazol-4-yl Chemical group 0.000 claims 1
- 241000255925 Diptera Species 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000000034 method Methods 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 208000027096 gram-negative bacterial infections Diseases 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461969735P | 2014-03-24 | 2014-03-24 | |
| US61/969,735 | 2014-03-24 | ||
| US201462088304P | 2014-12-05 | 2014-12-05 | |
| US62/088,304 | 2014-12-05 | ||
| PCT/US2015/022011 WO2015148379A1 (en) | 2014-03-24 | 2015-03-23 | Monobactam organic compounds for the treatment of bacterial infections |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017510580A JP2017510580A (ja) | 2017-04-13 |
| JP2017510580A5 true JP2017510580A5 (enExample) | 2017-06-01 |
| JP6153674B2 JP6153674B2 (ja) | 2017-06-28 |
Family
ID=52808201
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016558569A Active JP6153674B2 (ja) | 2014-03-24 | 2015-03-23 | 細菌感染を治療するためのモノバクタム有機化合物 |
Country Status (37)
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20201423T1 (hr) * | 2015-09-23 | 2020-12-11 | Novartis Ag | Soli i čvrsti oblici antibiotika monobaktam |
| US20180282331A1 (en) | 2015-11-09 | 2018-10-04 | Wockhardt Limited | 7-Oxo -6-(sulfooxy)- 1,6-diazabicyclo [3.2.1] octane containing compounds and their use in treatment of bacterial infections (changed by PCT to: 7-OXO -6-(SULFOOXY)- 1,6-DIAZABICYCLO [3.2.1] OCTANE CONTAINING COMPOUNDS AND THEIR USE IN TREATMENT OF BACTERIAL INFECTIONS |
| EP3390357B1 (en) * | 2015-12-15 | 2021-11-10 | Merck Sharp & Dohme Corp. | Biaryl monobactam compounds for the treatment of bacterial infections |
| MA43811A (fr) | 2016-03-07 | 2018-11-28 | Merck Sharp & Dohme | Composés d'arylmonobactame bicycliques et leurs méthodes d'utilisation pour le traitement des infections bactériennes |
| IL269390B (en) | 2017-03-20 | 2022-08-01 | Broad Inst Inc | Compounds and methods for the treatment of parasitic diseases |
| AU2018311521B2 (en) * | 2017-08-02 | 2022-03-03 | Novartis Ag | Process for preparing 1 -(((Z)-(1 -(2-aminothiazol-4-yl)-2-oxo-2-(((3S,4R)-2-oxo-4-((2-oxooxazolidin-3-y l)methyl)-1 -sulfoazetidin-3- yl)amino)ethylidene)amino)oxy)cyclopropane carboxylic acid |
| WO2019058346A1 (en) * | 2017-09-22 | 2019-03-28 | Novartis Ag | MONOBACTAM ADMINISTRATION IN ASSOCIATION WITH ANTIBIOTIC AGENT FOR THE TREATMENT OF COMPLICATED INTRA-ABDOMINAL INFECTION |
| CA3077474A1 (en) * | 2017-10-02 | 2019-04-11 | Arixa Pharmaceuticals, Inc. | Aztreonam derivatives and uses thereof |
| ES2968467T3 (es) | 2017-10-02 | 2024-05-09 | Merck Sharp & Dohme Llc | Compuestos monobactámicos de cromano para el tratamiento de infecciones bacterianas |
| US20200360349A1 (en) * | 2017-11-10 | 2020-11-19 | Novartis Ag | Administration of monobactam for the treatment of urinary tract infection |
| CN111511737B (zh) | 2018-01-29 | 2022-10-18 | 南京明德新药研发有限公司 | 用于治疗细菌感染的单环β-内酰胺化合物 |
| KR102017784B1 (ko) * | 2018-04-11 | 2019-09-03 | 전북대학교산학협력단 | 민감성 및 선택성을 개선한 캠필로박터 검출용 배지 조성물 및 이를 이용한 캠필로박터 검출방법 |
| KR102017785B1 (ko) * | 2018-05-17 | 2019-09-03 | 전북대학교산학협력단 | 민감성 및 선택성을 개선한 캠필로박터 선택증균용 배지 조성물 및 이를 이용한 캠필로박터 검출방법 |
| US11905286B2 (en) | 2018-08-09 | 2024-02-20 | Antabio Sas | Diazabicyclooctanones as inhibitors of serine beta-lactamases |
| DK3833665T3 (da) | 2018-08-09 | 2023-10-09 | Antabio Sas | Diazabicyclooctanoner som hæmmere af serin-beta-lactamaser |
| TW202024068A (zh) | 2018-11-13 | 2020-07-01 | 大陸商南京聖和藥業股份有限公司 | 單環內醯胺化合物及其應用 |
| WO2020125670A1 (zh) * | 2018-12-18 | 2020-06-25 | 南京明德新药研发有限公司 | 单环β-内酰胺化合物在制药中的应用 |
| WO2021098840A1 (zh) * | 2019-11-22 | 2021-05-27 | 南京明德新药研发有限公司 | 磺酰脲环取代的单环β-内酰胺类抗生素 |
| CN111303144B (zh) * | 2019-12-13 | 2020-11-27 | 苏州信诺维医药科技有限公司 | 一种治疗细菌感染的化合物 |
| EP4079305A4 (en) | 2019-12-19 | 2024-01-10 | Shenzhen Optimum Biological Technology Co., Ltd | APPLICATION OF A COMPOUND IN THE PREPARATION OF DRUG |
| EP3838266A1 (en) | 2019-12-20 | 2021-06-23 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Microfluidic production of biofunctionalized giant unilamellar vesicles for targeted intracellular cargo delivery |
| CN113754651B (zh) * | 2020-06-02 | 2023-04-18 | 中国医学科学院医药生物技术研究所 | 一种β-内酰胺化合物、其用途及其制备方法 |
| EP4165039B1 (en) * | 2020-07-16 | 2024-08-21 | Ningxia Academy of Agriculture and Forestry Sciences | Novel monobactam compounds, their preparation and use as antibacterial agents |
| WO2022185241A1 (en) | 2021-03-04 | 2022-09-09 | Bp Asset Vi, Inc. | Process for manufacturing a monobactam antibiotic |
| WO2022185240A1 (en) | 2021-03-04 | 2022-09-09 | Bp Asset Vi, Inc. | Formulation of a monobactam antibiotic |
| MX2024006075A (es) * | 2021-11-18 | 2024-05-30 | Merck Sharp & Dohme Llc | Antibioticos monobactamicos de cromano amidina. |
| CN115304594B (zh) | 2022-10-12 | 2023-02-14 | 苏州二叶制药有限公司 | 磺酰脲环取代的化合物的盐型及其晶型 |
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2015
- 2015-03-23 SI SI201530680T patent/SI3122745T1/sl unknown
- 2015-03-23 SG SG11201606711UA patent/SG11201606711UA/en unknown
- 2015-03-23 EP EP15714147.4A patent/EP3122745B1/en active Active
- 2015-03-23 US US14/665,245 patent/US9174978B2/en active Active
- 2015-03-23 PE PE2016001601A patent/PE20161371A1/es unknown
- 2015-03-23 PT PT15714147T patent/PT3122745T/pt unknown
- 2015-03-23 UA UAA201608977A patent/UA121383C2/uk unknown
- 2015-03-23 ES ES15714147T patent/ES2719136T3/es active Active
- 2015-03-23 ES ES18215940T patent/ES2862203T3/es active Active
- 2015-03-23 CN CN201580015867.7A patent/CN106164072B/zh active Active
- 2015-03-23 MX MX2016011822A patent/MX373444B/es active IP Right Grant
- 2015-03-23 MY MYPI2016702871A patent/MY179292A/en unknown
- 2015-03-23 AP AP2016009374A patent/AP2016009374A0/en unknown
- 2015-03-23 SM SM20190218T patent/SMT201900218T1/it unknown
- 2015-03-23 EP EP18215940.0A patent/EP3511328B1/en active Active
- 2015-03-23 MA MA39777A patent/MA39777B1/fr unknown
- 2015-03-23 KR KR1020167024716A patent/KR101733441B1/ko active Active
- 2015-03-23 JP JP2016558569A patent/JP6153674B2/ja active Active
- 2015-03-23 BR BR112016020333-0A patent/BR112016020333B1/pt active IP Right Grant
- 2015-03-23 PL PL15714147T patent/PL3122745T3/pl unknown
- 2015-03-23 DK DK15714147.4T patent/DK3122745T3/en active
- 2015-03-23 LT LTEP15714147.4T patent/LT3122745T/lt unknown
- 2015-03-23 CA CA2939254A patent/CA2939254C/en active Active
- 2015-03-23 HU HUE15714147A patent/HUE042134T2/hu unknown
- 2015-03-23 TW TW104109243A patent/TWI714525B/zh active
- 2015-03-23 WO PCT/US2015/022011 patent/WO2015148379A1/en not_active Ceased
- 2015-03-23 CU CU2016000131A patent/CU24441B1/es unknown
- 2015-03-23 EA EA201691766A patent/EA030850B1/ru not_active IP Right Cessation
- 2015-03-23 RS RS20190406A patent/RS58509B1/sr unknown
- 2015-03-23 DK DK18215940.0T patent/DK3511328T3/da active
- 2015-03-23 HR HRP20190501TT patent/HRP20190501T1/hr unknown
- 2015-03-23 AU AU2015236369A patent/AU2015236369B2/en active Active
- 2015-03-23 PH PH1/2016/501577A patent/PH12016501577B1/en unknown
- 2015-09-22 US US14/861,797 patent/US10369138B2/en active Active
-
2016
- 2016-08-11 ZA ZA2016/05565A patent/ZA201605565B/en unknown
- 2016-08-14 IL IL247259A patent/IL247259B/en active IP Right Grant
- 2016-09-09 CL CL2016002285A patent/CL2016002285A1/es unknown
- 2016-09-12 SV SV2016005274A patent/SV2016005274A/es unknown
- 2016-09-12 EC ECIEPI201673620A patent/ECSP16073620A/es unknown
- 2016-09-12 GT GT201600183A patent/GT201600183A/es unknown
-
2019
- 2019-04-03 CY CY20191100371T patent/CY1121701T1/el unknown
- 2019-04-10 US US16/380,243 patent/US20190231752A1/en not_active Abandoned
-
2020
- 2020-03-19 US US16/823,485 patent/US20200276169A1/en not_active Abandoned
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