JP2018523675A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018523675A5 JP2018523675A5 JP2018507672A JP2018507672A JP2018523675A5 JP 2018523675 A5 JP2018523675 A5 JP 2018523675A5 JP 2018507672 A JP2018507672 A JP 2018507672A JP 2018507672 A JP2018507672 A JP 2018507672A JP 2018523675 A5 JP2018523675 A5 JP 2018523675A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- compound
- pharmaceutical formulation
- streptococcus
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 8
- 208000035143 Bacterial infection Diseases 0.000 claims 7
- 208000022362 bacterial infectious disease Diseases 0.000 claims 7
- 150000001875 compounds Chemical class 0.000 claims 7
- 239000000825 pharmaceutical preparation Substances 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 5
- QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical class N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 claims 3
- 241000588770 Proteus mirabilis Species 0.000 claims 3
- 241000191967 Staphylococcus aureus Species 0.000 claims 3
- 239000003937 drug carrier Substances 0.000 claims 3
- 238000009472 formulation Methods 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 241000588626 Acinetobacter baumannii Species 0.000 claims 2
- 241000589513 Burkholderia cepacia Species 0.000 claims 2
- 241000194032 Enterococcus faecalis Species 0.000 claims 2
- 241000194031 Enterococcus faecium Species 0.000 claims 2
- 241000588724 Escherichia coli Species 0.000 claims 2
- 241000606768 Haemophilus influenzae Species 0.000 claims 2
- 241000588915 Klebsiella aerogenes Species 0.000 claims 2
- 241000588747 Klebsiella pneumoniae Species 0.000 claims 2
- 241000589242 Legionella pneumophila Species 0.000 claims 2
- RJQXTJLFIWVMTO-TYNCELHUSA-N Methicillin Chemical compound COC1=CC=CC(OC)=C1C(=O)N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@@H]21 RJQXTJLFIWVMTO-TYNCELHUSA-N 0.000 claims 2
- 241000588655 Moraxella catarrhalis Species 0.000 claims 2
- 241000589517 Pseudomonas aeruginosa Species 0.000 claims 2
- 241000607715 Serratia marcescens Species 0.000 claims 2
- 241000122973 Stenotrophomonas maltophilia Species 0.000 claims 2
- 241000193985 Streptococcus agalactiae Species 0.000 claims 2
- 241000193998 Streptococcus pneumoniae Species 0.000 claims 2
- 241000193996 Streptococcus pyogenes Species 0.000 claims 2
- 229940092559 enterobacter aerogenes Drugs 0.000 claims 2
- 229940032049 enterococcus faecalis Drugs 0.000 claims 2
- 229940047650 haemophilus influenzae Drugs 0.000 claims 2
- 229940115932 legionella pneumophila Drugs 0.000 claims 2
- 229960003085 meticillin Drugs 0.000 claims 2
- 229940031000 streptococcus pneumoniae Drugs 0.000 claims 2
- 208000019206 urinary tract infection Diseases 0.000 claims 2
- 241000217846 Bacteroides caccae Species 0.000 claims 1
- 241000606124 Bacteroides fragilis Species 0.000 claims 1
- 241001135228 Bacteroides ovatus Species 0.000 claims 1
- 241000315377 Bremia ovata Species 0.000 claims 1
- 241000588923 Citrobacter Species 0.000 claims 1
- 101710200331 Cytochrome b-245 chaperone 1 Proteins 0.000 claims 1
- 102100037186 Cytochrome b-245 chaperone 1 Human genes 0.000 claims 1
- 101710119396 Cytochrome b-245 chaperone 1 homolog Proteins 0.000 claims 1
- 241000588914 Enterobacter Species 0.000 claims 1
- 241000588697 Enterobacter cloacae Species 0.000 claims 1
- 241001505295 Eros Species 0.000 claims 1
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 claims 1
- 241000588768 Providencia Species 0.000 claims 1
- 241000588777 Providencia rettgeri Species 0.000 claims 1
- 241000295644 Staphylococcaceae Species 0.000 claims 1
- 241000122971 Stenotrophomonas Species 0.000 claims 1
- 241000194017 Streptococcus Species 0.000 claims 1
- 210000003555 cloaca Anatomy 0.000 claims 1
- 241000894007 species Species 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562205732P | 2015-08-16 | 2015-08-16 | |
| US62/205,732 | 2015-08-16 | ||
| US201662308928P | 2016-03-16 | 2016-03-16 | |
| US62/308,928 | 2016-03-16 | ||
| PCT/IB2016/054890 WO2017029602A2 (en) | 2015-08-16 | 2016-08-15 | Compounds for use in antibacterial applications |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018523675A JP2018523675A (ja) | 2018-08-23 |
| JP2018523675A5 true JP2018523675A5 (enExample) | 2019-09-26 |
| JP6757402B2 JP6757402B2 (ja) | 2020-09-16 |
Family
ID=57218948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018507672A Expired - Fee Related JP6757402B2 (ja) | 2015-08-16 | 2016-08-15 | ピラジノ［２，３−ｂ］［１，４］オキサジン−３−オン又は関連する環系を含む抗菌剤 |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US10364254B2 (enExample) |
| EP (1) | EP3334739A2 (enExample) |
| JP (1) | JP6757402B2 (enExample) |
| KR (1) | KR20180038046A (enExample) |
| CN (1) | CN108137616B (enExample) |
| AU (2) | AU2016307969C1 (enExample) |
| CA (1) | CA2995715A1 (enExample) |
| CL (1) | CL2018000403A1 (enExample) |
| CO (1) | CO2018002204A2 (enExample) |
| CR (1) | CR20180111A (enExample) |
| DO (1) | DOP2018000049A (enExample) |
| EA (1) | EA033314B1 (enExample) |
| HK (1) | HK1248680A1 (enExample) |
| IL (1) | IL257265B (enExample) |
| MA (1) | MA42621A (enExample) |
| MX (1) | MX2018002033A (enExample) |
| PE (1) | PE20181143A1 (enExample) |
| PH (1) | PH12018500358A1 (enExample) |
| TW (1) | TW201722965A (enExample) |
| UY (1) | UY36851A (enExample) |
| WO (1) | WO2017029602A2 (enExample) |
| ZA (1) | ZA201800722B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UY36851A (es) * | 2015-08-16 | 2017-03-31 | Glaxosmithkline Ip Dev Ltd | Compuestos para uso en aplicaciones antibacterianas |
| WO2019180634A1 (en) | 2018-03-23 | 2019-09-26 | Glaxosmithkline Intellectual Property Development Limited | Synthesis of oxazinone-containing bicyclic aromatic and heteroaromatic aldehydes |
| TW202116782A (zh) | 2019-07-16 | 2021-05-01 | 瑞士商愛杜西亞製藥有限公司 | 喹啉酮衍生物 |
| CN111269247B (zh) * | 2020-03-04 | 2020-11-24 | 河南科技大学第一附属医院 | 具有抑制大肠杆菌作用的噻嗪酮药物分子的制备方法 |
| KR20240161147A (ko) | 2022-03-14 | 2024-11-12 | 슬랩 파마슈티컬스 엘엘씨 | 다중 사이클릭 화합물 |
| AR134764A1 (es) | 2023-12-21 | 2026-04-01 | Glaxosmithkline Intellectual Property No 4 Ltd | Compuestos químicos y usos de los mismos |
Family Cites Families (88)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4632671B1 (enExample) * | 1969-10-13 | 1971-09-23 | Eisai Co Ltd | |
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| CY1308A (en) | 1979-12-06 | 1985-12-06 | Glaxo Group Ltd | Device for dispensing medicaments |
| ATE23272T1 (de) | 1981-07-08 | 1986-11-15 | Draco Ab | Pulverinhalator. |
| US4778054A (en) | 1982-10-08 | 1988-10-18 | Glaxo Group Limited | Pack for administering medicaments to patients |
| GB2169265B (en) | 1982-10-08 | 1987-08-12 | Glaxo Group Ltd | Pack for medicament |
| NL192564C (nl) | 1982-10-08 | 1997-10-03 | Glaxo Group Ltd | Inrichting voor het toedienen van medicamenten aan patiënten. |
| EP0211595B1 (en) | 1985-07-30 | 1991-11-13 | Glaxo Group Limited | Devices for administering medicaments to patients |
| JPH0733379B2 (ja) * | 1986-06-27 | 1995-04-12 | エーザイ株式会社 | 光学活性α−トコフエロ−ルの製造方法 |
| HU213221B (en) | 1990-03-02 | 1997-03-28 | Glaxo Group Ltd | Inhalation device and medicine packet for device |
| GB9004781D0 (en) | 1990-03-02 | 1990-04-25 | Glaxo Group Ltd | Device |
| US6536427B2 (en) | 1990-03-02 | 2003-03-25 | Glaxo Group Limited | Inhalation device |
| IL115849A0 (en) | 1994-11-03 | 1996-01-31 | Merz & Co Gmbh & Co | Tangential filtration preparation of liposomal drugs and liposome product thereof |
| GB9700226D0 (en) | 1997-01-08 | 1997-02-26 | Glaxo Group Ltd | Inhalation device |
| US5827533A (en) | 1997-02-06 | 1998-10-27 | Duke University | Liposomes containing active agents aggregated with lipid surfactants |
| FR2798656B1 (fr) | 1999-09-17 | 2004-12-17 | Aventis Pharma Sa | Derives de la quinolyl propyl piperidine, leur preparation et les compositions qui les contiennent |
| PL364808A1 (en) | 2000-07-21 | 2004-12-13 | Ljudmila Petrovna Maljuk | Plate for a stand-up meal |
| NZ523749A (en) | 2000-07-26 | 2005-03-24 | Smithkline Beecham P | Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity |
| FR2816618B1 (fr) | 2000-11-15 | 2002-12-27 | Aventis Pharma Sa | Derives heterocyclylalcoyl piperidine, leur preparation et les compositions qui les contiennent |
| GB0031088D0 (en) | 2000-12-20 | 2001-01-31 | Smithkline Beecham Plc | Medicaments |
| EP1345903A1 (en) | 2000-12-21 | 2003-09-24 | Ciba SC Holding AG | Crystalline forms of cerivastatin sodium |
| GB0101577D0 (en) | 2001-01-22 | 2001-03-07 | Smithkline Beecham Plc | Compounds |
| GB0112834D0 (en) * | 2001-05-25 | 2001-07-18 | Smithkline Beecham Plc | Medicaments |
| GB0112836D0 (en) | 2001-05-25 | 2001-07-18 | Smithkline Beecham Plc | Medicaments |
| GB0118238D0 (en) | 2001-07-26 | 2001-09-19 | Smithkline Beecham Plc | Medicaments |
| GB0201677D0 (en) | 2002-01-25 | 2002-03-13 | Glaxo Group Ltd | Medicament dispenser |
| WO2003064431A2 (en) | 2002-01-29 | 2003-08-07 | Glaxo Group Limited | Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them |
| US7312212B2 (en) | 2002-01-29 | 2007-12-25 | Glaxo Group Limited | Aminopiperidine derivatives |
| US20060014786A1 (en) * | 2002-05-17 | 2006-01-19 | Rajeev Raut | Opthalmic pharmaceutical compositions and methods for treating ocular inflammation |
| TW200406413A (en) | 2002-06-26 | 2004-05-01 | Glaxo Group Ltd | Compounds |
| TW200409637A (en) * | 2002-06-26 | 2004-06-16 | Glaxo Group Ltd | Compounds |
| CN100427487C (zh) | 2002-06-27 | 2008-10-22 | 弗·哈夫曼·拉罗切有限公司 | 嘌呤衍生物的合成 |
| GB0217294D0 (en) | 2002-07-25 | 2002-09-04 | Glaxo Group Ltd | Medicaments |
| FR2844268B1 (fr) | 2002-09-11 | 2004-10-22 | Aventis Pharma Sa | Derives de la quinolyl propyl piperidine, leurs procedes et intermediaires de preparation et les compositions qui les contiennent |
| FR2844270B1 (fr) | 2002-09-11 | 2006-05-19 | Aventis Pharma Sa | Derives de la quinolyl propyl piperidine, leur procede et intermediaires de preparation et les compositions qui les contiennent |
| EP1551829B1 (de) | 2002-10-10 | 2010-04-07 | Morphochem Aktiengesellschaft Für Kombinatorische Chemie | Neue verbindungen mit antibakterieller aktivität |
| AU2003291227A1 (en) | 2002-11-05 | 2004-06-07 | Smithkline Beecham Corporation | Antibacterial agents |
| ES2340484T3 (es) | 2002-11-05 | 2010-06-04 | Glaxo Group Limited | Agentes antibacterianos. |
| AR042486A1 (es) | 2002-12-18 | 2005-06-22 | Glaxo Group Ltd | Compuesto de quinolina y naftiridina halosustituido en la posicion 3, procedimiento para preparar el compuesto, composicion farmaceutica que lo comprende y su uso para preparar dicha composicion . |
| TW200507841A (en) * | 2003-03-27 | 2005-03-01 | Glaxo Group Ltd | Antibacterial agents |
| FR2852954B1 (fr) | 2003-03-28 | 2006-07-14 | Aventis Pharma Sa | Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent |
| DE10316081A1 (de) | 2003-04-08 | 2004-10-21 | Morphochem AG Aktiengesellschaft für kombinatorische Chemie | Neue Verbindungen mit antibakterieller Aktivität |
| FR2858619B1 (fr) | 2003-08-08 | 2006-12-22 | Aventis Pharma Sa | Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent |
| US9214590B2 (en) | 2003-12-19 | 2015-12-15 | The University Of North Carolina At Chapel Hill | High fidelity nano-structures and arrays for photovoltaics and methods of making the same |
| US8263129B2 (en) | 2003-12-19 | 2012-09-11 | The University Of North Carolina At Chapel Hill | Methods for fabricating isolated micro-and nano-structures using soft or imprint lithography |
| FR2867472B1 (fr) | 2004-03-12 | 2008-07-18 | Aventis Pharma Sa | Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent |
| JP2008502689A (ja) | 2004-06-15 | 2008-01-31 | グラクソ グループ リミテッド | 抗菌剤 |
| FR2872164B1 (fr) | 2004-06-29 | 2006-11-17 | Aventis Pharma Sa | Derives de quinoleines-4-substituees, leur procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent |
| EP1773831A1 (en) | 2004-07-08 | 2007-04-18 | Glaxo Group Limited | Antibacterial agents |
| EP1773847A2 (en) * | 2004-07-09 | 2007-04-18 | Glaxo Group Limited | Antibacterial agents |
| JP2008506695A (ja) | 2004-07-13 | 2008-03-06 | グラクソ グループ リミテッド | 抗細菌剤 |
| JP2008507543A (ja) | 2004-07-22 | 2008-03-13 | グラクソ グループ リミテッド | 抗細菌剤 |
| JP2008508359A (ja) | 2004-08-02 | 2008-03-21 | グラクソ グループ リミテッド | 抗菌剤 |
| JP2008509222A (ja) | 2004-08-09 | 2008-03-27 | グラクソ グループ リミテッド | 抗菌剤 |
| DE102004041163A1 (de) * | 2004-08-25 | 2006-03-02 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Neue Verbindungen mit antibakterieller Aktivität |
| JP4887297B2 (ja) | 2004-09-24 | 2012-02-29 | アクテリオン ファーマシューティカルズ リミテッド | 新規二環式抗生物質 |
| DE602005021133D1 (de) | 2004-10-05 | 2010-06-17 | Actelion Pharmaceuticals Ltd | Neue piperidin-antibiotika |
| WO2006046552A1 (ja) | 2004-10-27 | 2006-05-04 | Toyama Chemical Co., Ltd. | 新規な含窒素複素環化合物およびその塩 |
| WO2006081264A1 (en) * | 2005-01-25 | 2006-08-03 | Glaxo Group Limited | Antibacterial agents |
| WO2006125974A1 (en) * | 2005-05-24 | 2006-11-30 | Astrazeneca Ab | Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity |
| MY150958A (en) | 2005-06-16 | 2014-03-31 | Astrazeneca Ab | Compounds for the treatment of multi-drug resistant bacterial infections |
| WO2006137485A1 (ja) | 2005-06-24 | 2006-12-28 | Toyama Chemical Co., Ltd. | 新規な含窒素複素環化合物およびその塩 |
| GB0515584D0 (en) | 2005-07-28 | 2005-09-07 | Glaxo Group Ltd | Medicament dispenser |
| EP1922364A4 (en) | 2005-08-09 | 2010-04-21 | Univ North Carolina | METHOD AND MATERIALS FOR PRODUCING MICROFLUIDIC DEVICES |
| AR058289A1 (es) | 2005-12-12 | 2008-01-30 | Glaxo Group Ltd | Colector para ser usado en dispensador de medicamento |
| DOP2006000268A (es) | 2005-12-22 | 2007-07-31 | Pfizer Prod Inc | Agentes antibacterianos |
| WO2007081876A2 (en) | 2006-01-04 | 2007-07-19 | Liquidia Technologies, Inc. | Nanostructured surfaces for biomedical/biomaterial applications and processes thereof |
| WO2007093963A1 (en) * | 2006-02-15 | 2007-08-23 | Actelion Pharmaceuticals Ltd | Ethanol or 1,2-ethanediol cyclohexyl antibiotic derivatives |
| MX2008014908A (es) | 2006-05-26 | 2009-05-13 | Toyama Chemical Co Ltd | Compuesto heterociclico nuevo o sal del mismo e intermedio del mismo. |
| EP1992628A1 (en) * | 2007-05-18 | 2008-11-19 | Glaxo Group Limited | Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones |
| US8465775B2 (en) | 2006-07-27 | 2013-06-18 | The University Of North Carolina At Chapel Hill | Nanoparticle fabrication methods, systems, and materials for fabricating artificial red blood cells |
| US8128393B2 (en) | 2006-12-04 | 2012-03-06 | Liquidia Technologies, Inc. | Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom |
| CL2007003693A1 (es) * | 2006-12-22 | 2008-06-27 | Actelion Pharmaceuticals Ltd | Compuestos derivados de pirido [3,2-b] [1,4] tiazina; composicion farmaceutica que contiene dichos compuestos; y su uso en el tratamiento de infecciones bacterianas. |
| GB0707704D0 (en) * | 2007-04-20 | 2007-05-30 | Glaxo Group Ltd | Compounds |
| WO2009024342A2 (en) * | 2007-08-23 | 2009-02-26 | Syngenta Participations Ag | Novel microbiocides |
| CN101896337B (zh) | 2007-10-12 | 2013-10-30 | 流体科技公司 | 用于生产颗粒和图案化膜的系统和方法 |
| JP5620636B2 (ja) | 2007-11-26 | 2014-11-05 | 富山化学工業株式会社 | 新規な複素環化合物またはその塩を含有する抗菌剤 |
| KR101294962B1 (ko) * | 2008-10-07 | 2013-08-12 | 액테리온 파마슈티칼 리미티드 | 트리사이클 옥사졸리디논 항생제 화합물 |
| WO2010045987A1 (en) * | 2008-10-23 | 2010-04-29 | Glaxo Group Limited | Substituted (aza) -1-methyl-1h-quin0lin-2-0nes as antibacterials |
| TW201022279A (en) * | 2008-11-14 | 2010-06-16 | Astrazeneca Ab | Chemical compounds |
| KR101880582B1 (ko) | 2008-12-05 | 2018-07-20 | 리퀴디아 테크놀로지스 인코포레이티드 | 패턴 재료 제조 방법 |
| CN102232078B (zh) * | 2008-12-12 | 2014-07-16 | 埃科特莱茵药品有限公司 | 5-氨基-2-(1-羟基-乙基)-四氢吡喃衍生物 |
| WO2011008737A2 (en) | 2009-07-13 | 2011-01-20 | The University Of North Carolina At Chapel Hill | Engineered aerosol particles, and associated methods |
| TW201209056A (en) * | 2010-05-25 | 2012-03-01 | Taisho Pharmaceutical Co Ltd | Novel heterocyclic compound or salt thereof |
| AU2012275499A1 (en) * | 2011-06-27 | 2013-12-19 | Kyorin Pharmaceutical Co., Ltd. | Bridged bicyclic compounds for the treatment of bacterial infections |
| EP2785721A1 (en) * | 2011-11-30 | 2014-10-08 | Actelion Pharmaceuticals Ltd. | 3,7-disubstituted octahydro-2h-pyrido[4,3-e][1,3]oxazin-2-one antibiotics |
| EA029361B1 (ru) | 2013-04-16 | 2018-03-30 | Идорсиа Фармасьютиклз Лтд | Антибактериальные биароматические производные |
| UY36851A (es) * | 2015-08-16 | 2017-03-31 | Glaxosmithkline Ip Dev Ltd | Compuestos para uso en aplicaciones antibacterianas |
-
2016
- 2016-08-12 UY UY0001036851A patent/UY36851A/es not_active Application Discontinuation
- 2016-08-12 TW TW105125824A patent/TW201722965A/zh unknown
- 2016-08-15 EP EP16788799.1A patent/EP3334739A2/en not_active Withdrawn
- 2016-08-15 JP JP2018507672A patent/JP6757402B2/ja not_active Expired - Fee Related
- 2016-08-15 CA CA2995715A patent/CA2995715A1/en not_active Abandoned
- 2016-08-15 HK HK18108126.0A patent/HK1248680A1/zh unknown
- 2016-08-15 MA MA042621A patent/MA42621A/fr unknown
- 2016-08-15 US US15/752,639 patent/US10364254B2/en not_active Expired - Fee Related
- 2016-08-15 EA EA201890412A patent/EA033314B1/ru not_active IP Right Cessation
- 2016-08-15 WO PCT/IB2016/054890 patent/WO2017029602A2/en not_active Ceased
- 2016-08-15 CN CN201680056596.4A patent/CN108137616B/zh not_active Expired - Fee Related
- 2016-08-15 CR CR20180111A patent/CR20180111A/es unknown
- 2016-08-15 KR KR1020187007548A patent/KR20180038046A/ko not_active Withdrawn
- 2016-08-15 MX MX2018002033A patent/MX2018002033A/es unknown
- 2016-08-15 PE PE2018000236A patent/PE20181143A1/es unknown
- 2016-08-15 AU AU2016307969A patent/AU2016307969C1/en not_active Ceased
-
2018
- 2018-01-31 IL IL257265A patent/IL257265B/en active IP Right Grant
- 2018-02-02 ZA ZA2018/00722A patent/ZA201800722B/en unknown
- 2018-02-14 CL CL2018000403A patent/CL2018000403A1/es unknown
- 2018-02-15 PH PH12018500358A patent/PH12018500358A1/en unknown
- 2018-02-16 DO DO2018000049A patent/DOP2018000049A/es unknown
- 2018-02-27 CO CONC2018/0002204A patent/CO2018002204A2/es unknown
-
2019
- 2019-01-14 AU AU2019200226A patent/AU2019200226B2/en not_active Ceased
- 2019-05-17 US US16/415,319 patent/US10683307B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2017510580A5 (enExample) | ||
| CN114269746A (zh) | 一种螺芳环化合物、其制备及应用 | |
| JP2011530534A5 (enExample) | ||
| JOP20200130B1 (ar) | مركبات كرومان مونوباكتام لعلاج العدوى البكتيرية | |
| JP2013253094A5 (enExample) | ||
| MX2018010878A (es) | Compuestos de aril-monobactam biciclicos y metodos de uso de los mismos para el tratamiento de infecciones bacterianas. | |
| SA521431048B1 (ar) | مركبات بيروليدين | |
| HRP20190603T1 (hr) | 2-supstituirani spojevi cefema | |
| MX385507B (es) | Compuestos inhibidores de beta-lactamasa | |
| IN2014MN01882A (enExample) | ||
| RU2014143821A (ru) | 1, 3, 4-ОКСАДИАЗОЛЬНЫЕ И 1, 3, 4-ТИАДИАЗОЛЬНЫЕ ИНГИБИТОРЫ β-ЛАКТАМАЗЫ | |
| JP2014051497A5 (enExample) | ||
| TW201713633A (en) | Metallo-beta-lactamase inhibitors | |
| JP2018531941A5 (enExample) | ||
| BR112017010132A2 (pt) | terapia combinada para tratamento de infecções bacterianas resistentes | |
| BR112014004704A2 (pt) | compostos antibacterianos e métodos de uso | |
| HRP20191295T1 (hr) | Kristalne soli amida (4s,4as,5ar,12as)-4-dimetilamino-3,10,12,12a-tetrahidroksi-7-[(metoksi(metil)amino)-metil]-1,11-diokso-1,4,4a,5,5a,6,11,12a-oktahidro-naftacen-2-karboksilne kiseline i postupci uporabe istih | |
| JP2017517547A5 (enExample) | ||
| NZ740051A (en) | Tetracycline compounds | |
| Kanj et al. | In vitro activity of tigecycline and comparators against Gram-positive and Gram-negative isolates collected from the Middle East and Africa between 2004 and 2011 | |
| JP2020513808A5 (enExample) | ||
| JP2016505007A5 (enExample) | ||
| JP2021528449A5 (enExample) | ||
| JP2016520599A5 (enExample) | ||
| JP2019501896A5 (enExample) |