JP2017008120A5 - - Google Patents

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JP2017008120A5
JP2017008120A5 JP2016206062A JP2016206062A JP2017008120A5 JP 2017008120 A5 JP2017008120 A5 JP 2017008120A5 JP 2016206062 A JP2016206062 A JP 2016206062A JP 2016206062 A JP2016206062 A JP 2016206062A JP 2017008120 A5 JP2017008120 A5 JP 2017008120A5
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following formula
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following
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JP6326570B2 (ja
JP2017008120A (ja
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JP2016206062A 2010-03-25 2016-10-20 （Ｒ）−１−（２，２−ジフルオロベンゾ［ｄ］［１，３］ジオキソール−５−イル）−Ｎ−（１−（２，３−ジヒドロキシプロピル）−６−フルオロ−２−（１−ヒドロキシ−２−メチルプロパン−２−イル）−１Ｈ−インドール−５−イル）シクロプロパンカルボキサミドの固体形態 Active JP6326570B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2017245323A JP6913623B2 (ja) 2010-03-25 2017-12-21 （Ｒ）−１−（２，２−ジフルオロベンゾ［ｄ］［１，３］ジオキソール−５−イル）−Ｎ−（１−（２，３−ジヒドロキシプロピル）−６−フルオロ−２−（１−ヒドロキシ−２−メチルプロパン−２−イル）−１Ｈ−インドール−５−イル）シクロプロパンカルボキサミドの固体形態

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US31737610P 2010-03-25 2010-03-25
US61/317,376 2010-03-25
US31995310P 2010-04-01 2010-04-01
US61/319,953 2010-04-01
US32163610P 2010-04-07 2010-04-07
US32156110P 2010-04-07 2010-04-07
US61/321,561 2010-04-07
US61/321,636 2010-04-07

Related Parent Applications (1)

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JP2015046120A Division JP2015127334A (ja) 2010-03-25 2015-03-09 （Ｒ）−１−（２，２−ジフルオロベンゾ［ｄ］［１，３］ジオキソール−５−イル）−Ｎ−（１−（２，３−ジヒドロキシプロピル）−６−フルオロ−２−（１−ヒドロキシ−２−メチルプロパン−２−イル）−１Ｈ−インドール−５−イル）シクロプロパンカルボキサミドの固体形態

Related Child Applications (1)

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JP2017245323A Division JP6913623B2 (ja) 2010-03-25 2017-12-21 （Ｒ）−１−（２，２−ジフルオロベンゾ［ｄ］［１，３］ジオキソール−５−イル）−Ｎ−（１−（２，３−ジヒドロキシプロピル）−６−フルオロ−２−（１−ヒドロキシ−２−メチルプロパン−２−イル）−１Ｈ−インドール−５−イル）シクロプロパンカルボキサミドの固体形態

Publications (3)

Publication Number Publication Date
JP2017008120A JP2017008120A (ja) 2017-01-12
JP2017008120A5 true JP2017008120A5 (enExample) 2017-03-09
JP6326570B2 JP6326570B2 (ja) 2018-05-23

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ID=43903962

Family Applications (5)

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JP2013501522A Active JP5734410B2 (ja) 2010-03-25 2011-03-25 （Ｒ）−１−（２，２−ジフルオロベンゾ［ｄ］［１，３］ジオキソール−５−イル）−Ｎ−（１−（２，３−ジヒドロキシプロピル）−６−フルオロ−２−（１−ヒドロキシ−２−メチルプロパン−２−イル）−１Ｈ−インドール−５−イル）シクロプロパンカルボキサミドの固体形態
JP2015046120A Pending JP2015127334A (ja) 2010-03-25 2015-03-09 （Ｒ）−１−（２，２−ジフルオロベンゾ［ｄ］［１，３］ジオキソール−５−イル）−Ｎ−（１−（２，３−ジヒドロキシプロピル）−６−フルオロ−２−（１−ヒドロキシ−２−メチルプロパン−２−イル）−１Ｈ−インドール−５−イル）シクロプロパンカルボキサミドの固体形態
JP2016206062A Active JP6326570B2 (ja) 2010-03-25 2016-10-20 （Ｒ）−１−（２，２−ジフルオロベンゾ［ｄ］［１，３］ジオキソール−５−イル）−Ｎ−（１−（２，３−ジヒドロキシプロピル）−６−フルオロ−２−（１−ヒドロキシ−２−メチルプロパン−２−イル）−１Ｈ−インドール−５−イル）シクロプロパンカルボキサミドの固体形態
JP2017245323A Active JP6913623B2 (ja) 2010-03-25 2017-12-21 （Ｒ）−１−（２，２−ジフルオロベンゾ［ｄ］［１，３］ジオキソール−５−イル）−Ｎ−（１−（２，３−ジヒドロキシプロピル）−６−フルオロ−２−（１−ヒドロキシ−２−メチルプロパン−２−イル）−１Ｈ−インドール−５−イル）シクロプロパンカルボキサミドの固体形態
JP2020047688A Active JP6964702B2 (ja) 2010-03-25 2020-03-18 （Ｒ）−１−（２，２−ジフルオロベンゾ［ｄ］［１，３］ジオキソール−５−イル）−Ｎ−（１−（２，３−ジヒドロキシプロピル）−６−フルオロ−２−（１−ヒドロキシ−２−メチルプロパン−２−イル）−１Ｈ−インドール−５−イル）シクロプロパンカルボキサミドの固体形態

Family Applications Before (2)

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JP2013501522A Active JP5734410B2 (ja) 2010-03-25 2011-03-25 （Ｒ）−１−（２，２−ジフルオロベンゾ［ｄ］［１，３］ジオキソール−５−イル）−Ｎ−（１−（２，３−ジヒドロキシプロピル）−６−フルオロ−２−（１−ヒドロキシ−２−メチルプロパン−２−イル）−１Ｈ−インドール−５−イル）シクロプロパンカルボキサミドの固体形態
JP2015046120A Pending JP2015127334A (ja) 2010-03-25 2015-03-09 （Ｒ）−１−（２，２−ジフルオロベンゾ［ｄ］［１，３］ジオキソール−５−イル）−Ｎ−（１−（２，３−ジヒドロキシプロピル）−６−フルオロ−２−（１−ヒドロキシ−２−メチルプロパン−２−イル）−１Ｈ−インドール−５−イル）シクロプロパンカルボキサミドの固体形態

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2017245323A Active JP6913623B2 (ja) 2010-03-25 2017-12-21 （Ｒ）−１−（２，２−ジフルオロベンゾ［ｄ］［１，３］ジオキソール−５−イル）−Ｎ−（１−（２，３−ジヒドロキシプロピル）−６−フルオロ−２−（１−ヒドロキシ−２−メチルプロパン−２−イル）−１Ｈ−インドール−５−イル）シクロプロパンカルボキサミドの固体形態
JP2020047688A Active JP6964702B2 (ja) 2010-03-25 2020-03-18 （Ｒ）−１−（２，２−ジフルオロベンゾ［ｄ］［１，３］ジオキソール−５−イル）−Ｎ−（１−（２，３−ジヒドロキシプロピル）−６−フルオロ−２−（１−ヒドロキシ−２−メチルプロパン−２−イル）−１Ｈ−インドール−５−イル）シクロプロパンカルボキサミドの固体形態

Country Status (26)

Country Link
US (1) US20110251253A1 (enExample)
EP (5) EP3181561B1 (enExample)
JP (5) JP5734410B2 (enExample)
CN (3) CN106083832A (enExample)
AU (3) AU2011230508B2 (enExample)
BR (1) BR112012024338B1 (enExample)
CA (2) CA2794559C (enExample)
CY (3) CY1123794T1 (enExample)
DK (1) DK2826776T3 (enExample)
ES (4) ES2951520T3 (enExample)
FR (1) FR21C1018I2 (enExample)
HR (2) HRP20230661T1 (enExample)
HU (3) HUE062892T2 (enExample)
IL (4) IL222117B (enExample)
LT (2) LT2826776T (enExample)
LU (1) LUC00207I2 (enExample)
MX (3) MX370904B (enExample)
NO (1) NO2021021I1 (enExample)
NZ (3) NZ602665A (enExample)
PL (2) PL2826776T3 (enExample)
PT (1) PT2826776T (enExample)
RS (1) RS61314B1 (enExample)
RU (1) RU2711481C2 (enExample)
SI (1) SI2826776T1 (enExample)
SM (1) SMT202100051T1 (enExample)
WO (1) WO2011119984A1 (enExample)

Families Citing this family (110)

* Cited by examiner, † Cited by third party
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LT3150198T (lt) 2010-04-07 2021-12-10 Vertex Pharmaceuticals Incorporated 3-(6-(1-(2,2-difluorbenzo[d][1,3]dioksol-5-il) ciklopropankarboksamido)-3-metilpiridin-2-il)benzoinės rūgšties farmacinė kompozicija ir jos įvedimas
ME02446B (me) 2010-04-07 2016-09-20 Vertex Pharma Čvrste forme 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioksol-5-il)ciklopropankarboksiamido)-3-metilpiridin-2-il)benzoeve kiseline
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US8563593B2 (en) * 2010-06-08 2013-10-22 Vertex Pharmaceuticals Incorporated Formulations of (R)-1-(2,2-difluorobenzo[D] [1,3] dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide
CA2852991C (en) 2011-11-08 2019-12-31 Vertex Pharmaceuticals Incorporated Modulators of atp-binding cassette transporters
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CA3150162A1 (en) 2019-08-14 2021-02-18 Vertex Pharmaceuticals Incorporated Crystalline forms of cftr modulators
CA3150738A1 (en) 2019-08-14 2021-02-18 Vertex Pharmaceuticals Incorporated Modulators of cystic fibrosis transmembrane conductance regulator
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