JP2016512101A - 眼移植片を眼の脈絡膜上腔に送達するシステム及び方法 - Google Patents
眼移植片を眼の脈絡膜上腔に送達するシステム及び方法 Download PDFInfo
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- JP2016512101A JP2016512101A JP2016501670A JP2016501670A JP2016512101A JP 2016512101 A JP2016512101 A JP 2016512101A JP 2016501670 A JP2016501670 A JP 2016501670A JP 2016501670 A JP2016501670 A JP 2016501670A JP 2016512101 A JP2016512101 A JP 2016512101A
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- Prior art keywords
- graft
- obturator
- trigger
- implant
- trocar
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
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Abstract
Description
Claims (24)
- 送達装置及び移植片を備える眼移植片送達システムであって、
前記送達装置が、
人間工学的輪郭に合わせて作られた一般に細長い外側ハウジングと、
前記外側ハウジングに部分的に配置され、前記ハウジングの遠位端から延在する非線形露出遠位部を有する、細長い挿入スリーブと、
ここで、前記非線形露出遠位部は、眼の解剖学的曲率に適合するような曲率を有する、
前記挿入スリーブの管腔を通過し、前記挿入スリーブの前記非線形遠位部を越えて延在する非線形遠位部を有する、閉塞具と、
ここで、使用時、前記閉塞具の前記非線形遠位部は、毛様体筋付着部を通り脈絡膜上腔に接近するようになされる、
ここで、前記閉塞具の前記非線形遠位部は、柔軟であり、前記脈絡膜上腔への挿入中に強膜に対する圧力を維持するような曲率を有する、
前記閉塞具に操作可能に連結されたトリガーであって、前記トリガーが前記ハウジングの近位端方向に移動すると、前記閉塞具が前記挿入スリーブ内に後退する、トリガーと
を備え、
前記移植片が、前記送達装置を眼に挿入する前に、前記閉塞具の前記非線形部上に配置され、前記挿入スリーブの前記非線形遠位部の遠位に位置するようになされ、
使用時、前記閉塞具が後退すると、前記挿入スリーブの遠位端が前記移植片の近位端に反発して、前記移植片を送達するようになされた、
眼移植片送達システム。 - 前記挿入スリーブが、角膜切り込みを通って前眼房中に延在するサイズである請求項1に記載のシステム。
- 前記移植片が、前記閉塞具の前記非線形部の曲率にほぼ一致した曲率を有する請求項1に記載のシステム。
- 前記閉塞具の前記非線形遠位部の曲率、及び前記移植片の曲率が、眼の直径より大きい、請求項3に記載のシステム。
- 使用時、前記トリガーが、手動で制御され、前方位置に保持され、前記移植片の遠位端が脈絡膜上腔内の所望の場所に前進した後、後方移動で後退して、前記移植片を送達し、前記閉塞具の前記後方移動が、前記脈絡膜上腔内の前記移植片の挿入し過ぎを防止するようになされる請求項1〜4のいずれか一項に記載のシステム。
- 毛様体筋付着部を通り脈絡膜上腔に接近するようになされてはいるものの、強膜の擦過を起こさないように、前記閉塞具の遠位先端部が丸い請求項1〜5のいずれか一項に記載のシステム。
- 前記移植片が細長いチューブであり、前記移植片の外径が300から400ミクロンである請求項1〜6のいずれか一項に記載のシステム。
- 前記移植片の遠位部が複数の周囲保持部材を備える請求項1〜7のいずれか一項に記載のシステム。
- 前記移植片の遠位先端部が先細であり、前記移植片の近位端がフランジを備える請求項1〜8のいずれか一項に記載のシステム。
- 前記送達装置が、さらに、前記送達装置の再使用を防止するようになされた再使用防止構造体を備える請求項1〜9のいずれか一項に記載のシステム。
- 前記再使用防止構造体が、滅菌すると溶融して更なる使用に対して前記閉塞具のトリガーをロックするようになされた、前記トリガーの両側に搭載された一対の隅部材を備える請求項10に記載のシステム。
- 前記移植片がキットで提供され、前記移植片が前記閉塞具に前もって装着されている請求項1〜11のいずれか一項に記載のシステム。
- 人間工学的輪郭に合わせて作られた一般に細長い外側ハウジングと、
前記外側ハウジングに部分的に配置され、非線形露出遠位部を有する、細長い挿入針と、
前記細長い挿入針の管腔を通して延在し、非線形遠位部を有する、移植片推進チューブと、
前記推進チューブの管腔を通過し、非線形遠位部を有する、閉塞具と、
ここで、使用時、前記閉塞具の前記非線形遠位部は、毛様体筋付着部を通り脈絡膜上腔に接近するようになされる、
ここで、前記閉塞具の前記非線形遠位部は、柔軟であり、前記脈絡膜上腔への挿入中に強膜に対する圧力を維持するような曲率を有する、
前記推進チューブに操作可能に連結された推進チューブトリガーであって、前記推進チューブトリガーが前記ハウジングの近位端方向に移動すると、前記閉塞具が前記ハウジング方向に後退する、推進チューブトリガーと、
を備え、
使用時、前記閉塞具が前記ハウジング内に後退すると、前記推進チューブの遠位端が、前記閉塞具に装着された移植片の近位端に反発して、前記移植片を送達するようになされた、
眼移植片送達システム。 - 前記挿入針が、自己封着性角膜切り込みを形成するようになされた角膜穿通針である請求項13に記載のシステム。
- 前記挿入針、推進チューブ及び閉塞具の前記非線形部がほぼ一致した曲率を有する請求項13又は14に記載のシステム。
- さらに前記移植片を備え、前記移植片が、前記挿入針、推進チューブ及び閉塞具の曲率にほぼ適合した曲率を有する請求項15に記載のシステム。
- 前記推進チューブトリガーが前記閉塞具のトリガーに操作可能に連結された、請求項13〜16のいずれかに記載のシステム。
- 前記閉塞具が、前記閉塞具の前記トリガーの作動によって前進及び後退することができる請求項17に記載のシステム。
- 前記推進チューブが十分前進すると、ロックされて更なる移動を防止する請求項13〜18のいずれかに記載のシステム。
- さらに、使用を1回の使用に限定するように構成された再使用防止構造体を備える請求項13〜19のいずれかに記載のシステム。
- 前記再使用防止構造体が、滅菌すると溶融して更なる使用に対して前記推進チューブトリガーをロックするようになされた、前記推進チューブトリガーの両側に搭載された一対の隅部材を備える請求項20に記載のシステム。
- 前記挿入針が25±5ゲージ針を含む請求項13〜21のいずれかに記載のシステム。
- 前記移植片がキットで提供され、前記移植片が前記閉塞具に前もって装着されている請求項16に記載のシステム。
- 人間工学的輪郭に合わせて作られた一般に細長い外側ハウジングと、
前記外側ハウジングに部分的に配置され、非線形露出遠位部を有する、細長い挿入スリーブと、
前記細長い挿入スリーブの一部を包囲する管状支持部材であって、前記外側ハウジング内の近位端と前記外側ハウジングの外側に延在する遠位端とを有し、前記細長い挿入スリーブと前記外側ハウジングの連結を促進するように構成され、前記細長い挿入スリーブの一部を包囲する、前記管状支持部材と、
前記細長い挿入スリーブの管腔を通過し、前記細長い挿入スリーブの前記非線形露出遠位部を越えて延在する非線形遠位部を有する、閉塞具と、
前記閉塞具に操作可能に連結されたトリガーであって、前記トリガーが作動すると前記閉塞具が前記挿入スリーブ中に後退し、それによって前記閉塞具の前記非線形部上に配置された移植片の近位端が前記挿入スリーブの遠位端に反発して、前記閉塞具からの前記移植片の展開を容易にする、トリガーと
を備え、
前記移植片を有する前記閉塞具の前記非線形遠位部が、眼の脈絡膜上腔中に前進するように構成され、
前記閉塞具の前記非線形遠位部が、眼の直径より大きいように設計された曲率を有する、
眼移植片送達装置。
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US10285853B2 (en) | 2019-05-14 |
EP2967993B1 (en) | 2019-04-24 |
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JP6561041B2 (ja) | 2019-08-14 |
AU2014235331B2 (en) | 2019-03-07 |
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