|
US7803931B2
(en)
|
2004-02-12 |
2010-09-28 |
Archemix Corp. |
Aptamer therapeutics useful in the treatment of complement-related disorders
|
|
AR095196A1
(es)
|
2013-03-15 |
2015-09-30 |
Regeneron Pharma |
Medio de cultivo celular libre de suero
|
|
SG10201912985RA
(en)
|
2013-07-12 |
2020-02-27 |
Ophthotech Corp |
Methods for treating or preventing ophthalmological conditions
|
|
US9914769B2
(en)
|
2014-07-15 |
2018-03-13 |
Kymab Limited |
Precision medicine for cholesterol treatment
|
|
DE202014010499U1
(de)
|
2013-12-17 |
2015-10-20 |
Kymab Limited |
Targeting von humaner PCSK9 zur Cholesterinbehandlung
|
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
|
WO2015143271A1
(en)
*
|
2014-03-21 |
2015-09-24 |
X-Body, Inc. |
Bi-specific antigen-binding polypeptides
|
|
US9840553B2
(en)
|
2014-06-28 |
2017-12-12 |
Kodiak Sciences Inc. |
Dual PDGF/VEGF antagonists
|
|
BR112017009792A2
(pt)
*
|
2014-11-10 |
2018-02-27 |
Hoffmann La Roche |
anticorpos anti-pdgf-b e métodos de uso
|
|
AU2015345320A1
(en)
|
2014-11-10 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-IL-1beta antibodies and methods of use
|
|
KR20170080584A
(ko)
|
2014-11-10 |
2017-07-10 |
에프. 호프만-라 로슈 아게 |
이중특이적 항체 및 안과학에서 이의 사용 방법
|
|
EP3218398A1
(en)
|
2014-11-10 |
2017-09-20 |
F. Hoffmann-La Roche AG |
Anti-ang2 antibodies and methods of use
|
|
US20160144025A1
(en)
*
|
2014-11-25 |
2016-05-26 |
Regeneron Pharmaceuticals, Inc. |
Methods and formulations for treating vascular eye diseases
|
|
EA201791768A1
(ru)
*
|
2015-02-06 |
2018-07-31 |
КАДМОН КОРПОРЕЙШН, ЭлЭлСи |
Иммуномодулирующие агенты
|
|
JP6836512B2
(ja)
|
2015-03-31 |
2021-03-03 |
イルドン ファーム カンパニー リミテッド |
組織透過性ペプチドと抗血管内皮細胞成長因子製剤が融合された融合タンパク質を有効成分として含む眼疾患の予防及び治療用薬学的組成物
|
|
BR112018001762A2
(pt)
|
2015-07-29 |
2018-09-18 |
Allergan Inc |
anticorpos apenas de cadeia pesada para ang-2
|
|
TWI870789B
(zh)
|
2015-08-04 |
2025-01-21 |
美商再生元醫藥公司 |
補充牛磺酸之細胞培養基及用法
|
|
BR112018010743B1
(pt)
|
2015-12-16 |
2024-02-15 |
Regeneron Pharmaceuticals, Inc |
Método para fabricação de um pó farmacêutico formulado, e, pó farmacêutico formulado
|
|
WO2017117464A1
(en)
|
2015-12-30 |
2017-07-06 |
Kodiak Sciences Inc. |
Antibodies and conjugates thereof
|
|
IL263834B2
(en)
|
2016-06-20 |
2024-01-01 |
Kymab Ltd |
Anti-pd-l1 antibodies
|
|
AU2017290762B2
(en)
*
|
2016-07-01 |
2024-09-12 |
Paracrine Therapeutics Ab |
Methods and compositions for PDGF-CC inhibition
|
|
CA3031742A1
(en)
|
2016-08-16 |
2018-02-22 |
Regeneron Pharmaceuticals, Inc. |
Methods for quantitating individual antibodies from a mixture
|
|
WO2018039499A1
(en)
|
2016-08-24 |
2018-03-01 |
Regeneron Pharmaceuticals, Inc. |
Host cell protein modification
|
|
WO2018083248A1
(en)
|
2016-11-03 |
2018-05-11 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses & methods
|
|
CN109021104B
(zh)
*
|
2017-06-12 |
2022-08-12 |
上海睿智化学研究有限公司 |
一种抗人血小板衍生生长因子β受体的抗体及其应用
|
|
AU2018298039B2
(en)
|
2017-07-06 |
2023-02-02 |
Regeneron Pharmaceuticals, Inc. |
Cell culture process for making a glycoprotein
|
|
AU2018392334A1
(en)
|
2017-12-22 |
2020-05-28 |
Regeneron Pharmaceuticals, Inc. |
System and method for characterizing drug product impurities
|
|
SG11202005235WA
(en)
|
2018-01-31 |
2020-07-29 |
Regeneron Pharma |
System and method for characterizing size and charge variant drug product impurities
|
|
TWI786265B
(zh)
|
2018-02-02 |
2022-12-11 |
美商再生元醫藥公司 |
用於表徵蛋白質二聚合之系統及方法
|
|
CN111771000A
(zh)
|
2018-02-28 |
2020-10-13 |
瑞泽恩制药公司 |
用于鉴定病毒污染物的系统和方法
|
|
BR112020017872A2
(pt)
|
2018-03-02 |
2020-12-22 |
Kodiak Sciences Inc. |
Anticorpos de il-6 e construtos de fusão e conjugados dos mesmos
|
|
WO2019182901A1
(en)
|
2018-03-19 |
2019-09-26 |
Regeneron Pharmaceuticals, Inc. |
Microchip capillary electrophoresis assays and reagents
|
|
US12259355B2
(en)
|
2018-03-19 |
2025-03-25 |
Regeneron Pharmaceuticals, Inc. |
Microchip capillary electrophoresis assays and reagents
|
|
US12253490B2
(en)
|
2018-03-19 |
2025-03-18 |
Regeneron Pharmaceuticals, Inc. |
Microchip capillary electrophoresis assays and reagents
|
|
GB201806918D0
(en)
*
|
2018-04-27 |
2018-06-13 |
Enleofen Bio Pte Ltd |
Combination treatment for eye fibrosis
|
|
CN108586611B
(zh)
*
|
2018-04-28 |
2021-01-26 |
暨南大学 |
重组全人源抗破伤风毒素单克隆抗体
|
|
TW202016125A
(zh)
|
2018-05-10 |
2020-05-01 |
美商再生元醫藥公司 |
用於定量及調節蛋白質黏度之系統與方法
|
|
CN112218877B
(zh)
|
2018-08-27 |
2025-07-25 |
瑞泽恩制药公司 |
拉曼光谱在下游纯化中的应用
|
|
US11754569B2
(en)
|
2018-08-30 |
2023-09-12 |
Regeneron Pharmaceuticals, Inc. |
Methods for characterizing protein complexes
|
|
AU2019352482A1
(en)
*
|
2018-10-05 |
2021-05-13 |
Seoul National University R&Db Foundation |
PDGF receptor antibody and use thereof
|
|
EP3857236A1
(en)
|
2019-01-16 |
2021-08-04 |
Regeneron Pharmaceuticals, Inc. |
Methods for identifying free thiols in proteins
|
|
JP7603600B2
(ja)
*
|
2019-03-08 |
2024-12-20 |
リンクシス ベスローテン フェンノートシャップ |
細胞増殖又は細胞分化に関与する受容体を標的にする内在化結合分子
|
|
PH12021552763A1
(en)
|
2019-05-03 |
2022-07-04 |
Nat Univ Singapore |
Treatment and prevention of metabolic diseases
|
|
KR20220007586A
(ko)
|
2019-05-13 |
2022-01-18 |
리제너론 파마슈티칼스 인코포레이티드 |
개선된 경쟁적 리간드 결합 검정
|
|
IL317159A
(en)
|
2019-09-24 |
2025-01-01 |
Regeneron Pharma |
Systems and methods for use in chromatography and regeneration
|
|
CA3157509A1
(en)
|
2019-10-10 |
2021-04-15 |
Kodiak Sciences Inc. |
Methods of treating an eye disorder
|
|
US12297451B1
(en)
|
2019-10-25 |
2025-05-13 |
Regeneron Pharmaceuticals, Inc. |
Cell culture medium
|
|
CN114760986A
(zh)
|
2019-11-25 |
2022-07-15 |
里珍纳龙药品有限公司 |
使用非水性乳液的持续释放调配物
|
|
CA3164037A1
(en)
|
2020-01-08 |
2021-07-15 |
Synthis Therapeutics, Inc. |
Alk5 inhibitor conjugates and uses thereof
|
|
MX2022008973A
(es)
|
2020-01-21 |
2022-08-11 |
Regeneron Pharma |
Metodos de desglicosilacion para electroforesis de proteinas glicosiladas.
|
|
EP4100437A1
(en)
*
|
2020-02-07 |
2022-12-14 |
Biorion Technologies B.V. |
Platelet derived growth factor receptor (pdgfr) antibodies, conjugates, compositions, and uses thereof
|
|
WO2022047108A1
(en)
|
2020-08-31 |
2022-03-03 |
Regeneron Pharmaceuticals, Inc. |
Asparagine feed strategies to improve cell culture performance and mitigate asparagine sequence variants
|
|
EP4214235A1
(en)
*
|
2020-09-16 |
2023-07-26 |
LinXis B.V. |
Internalizing binding molecules
|
|
US12239687B2
(en)
|
2020-11-25 |
2025-03-04 |
Regeneron Pharmaceuticals, Inc. |
Sustained release formulations using non-aqueous membrane emulsification
|
|
KR20230121854A
(ko)
|
2020-12-17 |
2023-08-21 |
리제너론 파아마슈티컬스, 인크. |
단백질-캡슐화 마이크로겔의 제작
|
|
CA3202197A1
(en)
|
2021-01-20 |
2022-07-28 |
Reginald Smith |
Methods of improving protein titer in cell culture
|
|
EP4302098A1
(en)
|
2021-03-03 |
2024-01-10 |
Regeneron Pharmaceuticals, Inc. |
Systems and methods for quantifying and modifying protein viscosity
|
|
EP4315344A1
(en)
|
2021-03-26 |
2024-02-07 |
Regeneron Pharmaceuticals, Inc. |
Methods and systems for developing mixing protocols
|
|
CA3220848A1
(en)
|
2021-06-01 |
2022-12-08 |
Timothy Riehlman |
Microchip capillary electrophoresis assays and reagents
|
|
AR127006A1
(es)
|
2021-09-08 |
2023-12-06 |
Regeneron Pharma |
UN MÉTODO BASADO EN ESPECTROMETRÍA DE MASAS Y DE ALTO RENDIMIENTO PARA CUANTIFICAR ANTICUERPOS Y OTRAS PROTEÍNAS QUE CONTIENEN Fc
|
|
US20230090912A1
(en)
|
2021-09-20 |
2023-03-23 |
Regeneron Pharmaceuticals, Inc. |
Methods of controlling antibody heterogeneity
|
|
US20230116199A1
(en)
|
2021-10-07 |
2023-04-13 |
Regeneron Pharmaceuticals, Inc. |
Systems and methods of ph modeling and control
|
|
IL311248A
(en)
|
2021-10-07 |
2024-05-01 |
Regeneron Pharma |
PH meter calibration and repair
|
|
KR20240097864A
(ko)
|
2021-10-26 |
2024-06-27 |
리제너론 파마슈티칼스 인코포레이티드 |
상이한 온도에서 실험실 용수를 생성하고 실험실 용수를 분배하는 시스템 및 방법
|
|
EP4493921A1
(en)
|
2022-03-18 |
2025-01-22 |
Regeneron Pharmaceuticals, Inc. |
Methods and systems for analyzing polypeptide variants
|
|
US11723955B1
(en)
|
2022-05-13 |
2023-08-15 |
Allgenesis Biotherapeutics Inc. |
VEGFR fusion protein pharmaceutical composition
|
|
KR20250124178A
(ko)
|
2022-12-16 |
2025-08-19 |
리제너론 파아마슈티컬스, 인크. |
크로마토그래피 칼럼의 무결성을 평가하기 위한 방법 및 시스템
|
|
TW202445135A
(zh)
|
2023-01-25 |
2024-11-16 |
美商再生元醫藥公司 |
液態蛋白質組成物穩定性之建模方法
|
|
US20240248097A1
(en)
|
2023-01-25 |
2024-07-25 |
Regeneron Pharmaceuticals, Inc. |
Mass spectrometry-based characterization of antibodies co-expressed in vivo
|
|
WO2024163708A1
(en)
|
2023-02-01 |
2024-08-08 |
Regeneron Pharmaceuticals, Inc. |
Asymmetrical flow field-flow fractionation with mass spectrometry for biomacromolecule analysis
|
|
US20240280551A1
(en)
|
2023-02-22 |
2024-08-22 |
Regeneron Pharmaceuticals, Inc. |
System suitability parameters and column aging
|
|
AU2024265540A1
(en)
|
2023-05-01 |
2025-10-30 |
Regeneron Pharmaceuticals, Inc. |
Multidose antibody drug products using phenol or benzyl alcohol
|
|
WO2025054406A1
(en)
|
2023-09-08 |
2025-03-13 |
Regeneron Pharmaceuticals, Inc. |
Methods and systems for assessing chromatographic column integrity
|
|
WO2025064403A2
(en)
|
2023-09-18 |
2025-03-27 |
Regeneron Pharmaceuticals, Inc. |
Methods and systems for developing chromatography protocols
|
|
US20250109905A1
(en)
|
2023-09-29 |
2025-04-03 |
Regeneron Pharmaceuticals, Inc. |
Lyophilization using controlled nucleation
|
|
US20250129117A1
(en)
|
2023-10-18 |
2025-04-24 |
Regeneron Pharmaceuticals, Inc. |
Rapid purification of monoclonal antibody from in-process upstream cell culture material
|
|
US20250145662A1
(en)
|
2023-11-02 |
2025-05-08 |
Regeneron Pharmaceuticals, Inc. |
Methods for reducing lipase activity using stress
|
|
WO2025166281A1
(en)
|
2024-02-01 |
2025-08-07 |
Regeneron Pharmaceuticals, Inc. |
Platform for charge-detection mass spectrometry analysis of aavs
|
|
WO2025175164A1
(en)
|
2024-02-16 |
2025-08-21 |
Regeneron Pharmaceuticals, Inc. |
Methods of producing concentrated formulated drug substances comprising proteins, and concentrated formulated drug substance made by the methods
|
|
WO2025194043A1
(en)
|
2024-03-15 |
2025-09-18 |
Regeneron Pharmaceuticals, Inc. |
Polysorbate and polyoxyethylene sorbitan as excipients for stable protein formulations
|
|
CN118440214B
(zh)
*
|
2024-04-02 |
2025-01-28 |
山东大学 |
一种靶向PDGFRβ的嵌合抗原受体、CAR-T细胞及应用
|