JP2010528047A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010528047A5 JP2010528047A5 JP2010509554A JP2010509554A JP2010528047A5 JP 2010528047 A5 JP2010528047 A5 JP 2010528047A5 JP 2010509554 A JP2010509554 A JP 2010509554A JP 2010509554 A JP2010509554 A JP 2010509554A JP 2010528047 A5 JP2010528047 A5 JP 2010528047A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- antibody
- factor
- antagonist
- amd
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000005557 antagonist Substances 0.000 claims description 15
- 230000000295 complement effect Effects 0.000 claims description 15
- 206010064930 age-related macular degeneration Diseases 0.000 claims description 14
- 208000002780 macular degeneration Diseases 0.000 claims description 14
- 208000005590 Choroidal Neovascularization Diseases 0.000 claims description 10
- 206010060823 Choroidal neovascularisation Diseases 0.000 claims description 10
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims description 8
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims description 8
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims description 8
- 201000005667 central retinal vein occlusion Diseases 0.000 claims description 8
- 208000004644 retinal vein occlusion Diseases 0.000 claims description 8
- 239000012634 fragment Substances 0.000 claims description 6
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 6
- 206010055665 Corneal neovascularisation Diseases 0.000 claims description 4
- 206010012688 Diabetic retinal oedema Diseases 0.000 claims description 4
- 201000002563 Histoplasmosis Diseases 0.000 claims description 4
- 208000007135 Retinal Neovascularization Diseases 0.000 claims description 4
- 208000017442 Retinal disease Diseases 0.000 claims description 4
- 206010038923 Retinopathy Diseases 0.000 claims description 4
- 206010046851 Uveitis Diseases 0.000 claims description 4
- 201000000159 corneal neovascularization Diseases 0.000 claims description 4
- 208000001309 degenerative myopia Diseases 0.000 claims description 4
- 230000004340 degenerative myopia Effects 0.000 claims description 4
- 206010012601 diabetes mellitus Diseases 0.000 claims description 4
- 201000011190 diabetic macular edema Diseases 0.000 claims description 4
- 208000028867 ischemia Diseases 0.000 claims description 4
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 4
- 208000006542 von Hippel-Lindau disease Diseases 0.000 claims description 4
- 241000124008 Mammalia Species 0.000 claims description 2
- 208000000208 Wet Macular Degeneration Diseases 0.000 claims description 2
- 239000003814 drug Substances 0.000 claims description 2
- 208000011325 dry age related macular degeneration Diseases 0.000 claims description 2
- 229920001184 polypeptide Polymers 0.000 claims description 2
- 150000003384 small molecules Chemical class 0.000 claims description 2
- 230000002265 prevention Effects 0.000 claims 1
- 238000000034 method Methods 0.000 description 17
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93979107P | 2007-05-23 | 2007-05-23 | |
| US60/939,791 | 2007-05-23 | ||
| PCT/US2008/064526 WO2008147883A1 (en) | 2007-05-23 | 2008-05-22 | Prevention and treatment of complement-associated eye conditions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013236445A Division JP2014087346A (ja) | 2007-05-23 | 2013-11-15 | 補体が関係している眼の状態の予防および治療 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010528047A JP2010528047A (ja) | 2010-08-19 |
| JP2010528047A5 true JP2010528047A5 (enExample) | 2012-05-10 |
| JP5416695B2 JP5416695B2 (ja) | 2014-02-12 |
Family
ID=39638868
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010509554A Expired - Fee Related JP5416695B2 (ja) | 2007-05-23 | 2008-05-22 | 補体が関係している眼の状態の予防および治療 |
| JP2013236445A Withdrawn JP2014087346A (ja) | 2007-05-23 | 2013-11-15 | 補体が関係している眼の状態の予防および治療 |
| JP2016015288A Withdrawn JP2016145205A (ja) | 2007-05-23 | 2016-01-29 | 補体が関係している眼の状態の予防および治療 |
| JP2017146477A Pending JP2017197577A (ja) | 2007-05-23 | 2017-07-28 | 補体が関係している眼の状態の予防および治療 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013236445A Withdrawn JP2014087346A (ja) | 2007-05-23 | 2013-11-15 | 補体が関係している眼の状態の予防および治療 |
| JP2016015288A Withdrawn JP2016145205A (ja) | 2007-05-23 | 2016-01-29 | 補体が関係している眼の状態の予防および治療 |
| JP2017146477A Pending JP2017197577A (ja) | 2007-05-23 | 2017-07-28 | 補体が関係している眼の状態の予防および治療 |
Country Status (28)
| Country | Link |
|---|---|
| US (6) | US8007791B2 (enExample) |
| EP (1) | EP2152755B1 (enExample) |
| JP (4) | JP5416695B2 (enExample) |
| KR (1) | KR101540126B1 (enExample) |
| CN (3) | CN107096029B (enExample) |
| AR (1) | AR066660A1 (enExample) |
| AU (1) | AU2008256835B2 (enExample) |
| BR (1) | BRPI0811142A8 (enExample) |
| CA (1) | CA2683498A1 (enExample) |
| CL (1) | CL2008001498A1 (enExample) |
| CY (1) | CY1116062T1 (enExample) |
| DK (1) | DK2152755T3 (enExample) |
| ES (1) | ES2533242T3 (enExample) |
| HK (1) | HK1207327A1 (enExample) |
| HR (1) | HRP20150281T1 (enExample) |
| IL (2) | IL201476A (enExample) |
| MX (1) | MX2009012422A (enExample) |
| PE (1) | PE20090294A1 (enExample) |
| PH (1) | PH12013500992B1 (enExample) |
| PL (1) | PL2152755T3 (enExample) |
| PT (1) | PT2152755E (enExample) |
| RS (1) | RS53901B1 (enExample) |
| RU (2) | RU2522976C2 (enExample) |
| SG (1) | SG10201401404RA (enExample) |
| SI (1) | SI2152755T1 (enExample) |
| TW (2) | TWI419704B (enExample) |
| WO (1) | WO2008147883A1 (enExample) |
| ZA (1) | ZA200907028B (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2026073B1 (en) * | 2000-04-29 | 2016-03-30 | University Of Iowa Research Foundation | Diagnostics and therapeutics for macular degeneration-related disorders |
| NZ567483A (en) * | 2005-11-04 | 2012-04-27 | Genentech Inc | Use of complement pathway inhibitors to treat ocular diseases |
| SI2907827T1 (sl) | 2006-11-02 | 2019-02-28 | Genentech, Inc. | Humanizirana protitelesa proti faktorju D in njihova uporaba |
| AR066660A1 (es) * | 2007-05-23 | 2009-09-02 | Genentech Inc | Prevencion y tratamiento de condiciones del ojo asociadas con su complemento |
| CR20170001A (es) | 2008-04-28 | 2017-08-10 | Genentech Inc | Anticuerpos anti factor d humanizados |
| CA2735779A1 (en) * | 2008-09-02 | 2010-03-11 | Matthew Burger | Bicyclic kinase inhibitors |
| US8623395B2 (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
| AU2010208046B2 (en) | 2009-01-29 | 2014-10-02 | Forsight Vision4, Inc. | Posterior segment drug delivery |
| WO2010129609A2 (en) * | 2009-05-07 | 2010-11-11 | The Regents Of The University Of California | Antibodies and methods of use thereof |
| US20110165648A1 (en) * | 2009-11-04 | 2011-07-07 | Menno Van Lookeren Campagne | Co-crystal structure of factor D and anti-factor D antibody |
| JP5907966B2 (ja) | 2010-08-05 | 2016-04-26 | フォーサイト・ビジョン フォー・インコーポレーテッド | 埋め込み型治療デバイス |
| AR083677A1 (es) * | 2010-11-01 | 2013-03-13 | Genentech Inc | Prediccion del paso a degeneracion macular avanzada relacionada con la edad utilizando una puntuacion poligenica |
| WO2012093101A1 (en) | 2011-01-04 | 2012-07-12 | Novartis Ag | Indole compounds or analogues thereof useful for the treatment of age-related macular degeneration (amd) |
| WO2012103165A2 (en) | 2011-01-26 | 2012-08-02 | Kolltan Pharmaceuticals, Inc. | Anti-kit antibodies and uses thereof |
| WO2014002054A1 (en) | 2012-06-28 | 2014-01-03 | Novartis Ag | Pyrrolidine derivatives and their use as complement pathway modulators |
| JP6209605B2 (ja) | 2012-06-28 | 2017-10-04 | ノバルティス アーゲー | ピロリジン誘導体、および補体経路調節因子としてのその使用 |
| ES2648962T3 (es) | 2012-06-28 | 2018-01-09 | Novartis Ag | Derivados de pirrolidina y su uso como moduladores de la vía del complemento |
| WO2014002058A2 (en) | 2012-06-28 | 2014-01-03 | Novartis Ag | Complement pathway modulators and uses thereof |
| WO2014002051A2 (en) | 2012-06-28 | 2014-01-03 | Novartis Ag | Complement pathway modulators and uses thereof |
| EA201590200A1 (ru) | 2012-07-12 | 2015-08-31 | Новартис Аг | Модуляторы пути активации комплемента и их применение |
| CN116574185A (zh) | 2012-07-25 | 2023-08-11 | 塞尔德克斯医疗公司 | 抗kit抗体及其用途 |
| WO2014120555A1 (en) | 2013-01-31 | 2014-08-07 | The Regents Of The University Of California | Antibodies specific for urokinase-type plasminogen activator and methods of use thereof |
| EP2978393B1 (en) | 2013-03-28 | 2023-12-27 | ForSight Vision4, Inc. | Ophthalmic implant for delivering therapeutic substances |
| CN107318267B (zh) | 2013-08-12 | 2021-08-17 | 豪夫迈·罗氏有限公司 | 用于治疗补体相关的病症的组合物和方法 |
| WO2015054298A1 (en) * | 2013-10-07 | 2015-04-16 | Massachusetts Eye And Ear Infirmary | Methods of preventing or reducing photoreceptor cell death |
| CN105764533A (zh) * | 2013-10-25 | 2016-07-13 | 儿童医疗中心有限公司 | 治疗或预防视网膜血管疾病的方法 |
| PE20161440A1 (es) * | 2014-05-01 | 2017-01-26 | Genentech Inc | Variantes del anticuerpo anti-factor d y sus usos |
| EP3145543A4 (en) | 2014-05-23 | 2017-12-13 | Celldex Therapeutics, Inc. | Treatment of eosinophil or mast cell related disorders |
| KR102803519B1 (ko) * | 2015-09-23 | 2025-05-08 | 상가모 테라퓨틱스, 인코포레이티드 | Htt 리프레서 및 이의 용도 |
| JP6750010B2 (ja) | 2015-10-30 | 2020-09-02 | ジェネンテック， インコーポレイテッド | 抗ＨｔｒＡ１抗体及びその使用方法 |
| KR20180066242A (ko) | 2015-10-30 | 2018-06-18 | 제넨테크, 인크. | 인자 d 활성 및 인자 d 억제제의 효력을 측정하는 방법 |
| WO2017075173A2 (en) | 2015-10-30 | 2017-05-04 | Genentech, Inc. | Anti-factor d antibodies and conjugates |
| JP2018536650A (ja) * | 2015-10-30 | 2018-12-13 | ジェネンテック， インコーポレイテッド | 抗ｄ因子抗体変異体コンジュゲート及びその使用 |
| AU2016375183B2 (en) | 2015-12-23 | 2021-01-21 | eleva GmbH | Polypeptides for inhibiting complement activation |
| GB2553252B (en) * | 2016-01-20 | 2019-07-31 | Vitrisa Therapeutics Inc | Aptamers that block the catalytic cleft of complement Factor D |
| WO2018136827A1 (en) | 2017-01-20 | 2018-07-26 | Vitrisa Therapeutics, Inc. | Stem-loop compositions and methods for inhibiting factor d |
| KR20190129859A (ko) * | 2017-02-10 | 2019-11-20 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 항-d 인자 항체 및 그의 용도 |
| CN109632924B (zh) * | 2018-12-17 | 2022-02-08 | 上海市第一人民医院 | 人黄斑新生血管性疾病的血浆脂质标记物及其应用 |
| EP3999626A4 (en) * | 2019-07-18 | 2023-11-22 | Pandorum Technologies Private Limited | PROCESSES FOR CULTURE OF STEM CELLS TO OBTAIN PRODUCTS AND THEIR MODES OF PRODUCTION |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6620915B2 (en) * | 1993-12-23 | 2003-09-16 | Icos Corporation | Monoclonal antibodies specific for integrin α-d subunit |
| WO1999040100A1 (en) | 1998-02-09 | 1999-08-12 | Human Genome Sciences, Inc. | 45 human secreted proteins |
| US20050197285A1 (en) | 1997-03-07 | 2005-09-08 | Rosen Craig A. | Human secreted proteins |
| US6472520B2 (en) | 1997-03-21 | 2002-10-29 | The Trustees Of Columbia University In The City Of New York | Rat PEG-3 promoter |
| US6410708B1 (en) | 1997-11-21 | 2002-06-25 | Genentech, Inc. | Nucleic acids encoding A-33 related antigen polypeptides |
| US7192589B2 (en) | 1998-09-16 | 2007-03-20 | Genentech, Inc. | Treatment of inflammatory disorders with STIgMA immunoadhesins |
| US8088386B2 (en) | 1998-03-20 | 2012-01-03 | Genentech, Inc. | Treatment of complement-associated disorders |
| US7282565B2 (en) | 1998-03-20 | 2007-10-16 | Genentech, Inc. | PRO362 polypeptides |
| US8007798B2 (en) | 1997-11-21 | 2011-08-30 | Genentech, Inc. | Treatment of complement-associated disorders |
| DK1481989T3 (da) | 1997-11-21 | 2008-08-25 | Genentech Inc | A-33-beslægtede antigener og deres farmakologiske anvendelser |
| US7419663B2 (en) | 1998-03-20 | 2008-09-02 | Genentech, Inc. | Treatment of complement-associated disorders |
| US6956107B2 (en) | 1998-02-20 | 2005-10-18 | Tanox, Inc. | Inhibitors of complement activation |
| BRPI9909220B1 (pt) * | 1998-02-20 | 2018-09-18 | Genentech Inc | hibridoma, anticorpo monoclonal, anticorpo humanizado, anticorpo quimérico, anticorpo desimunizado ou fragmento de tais anticorpos |
| ES2312205T3 (es) | 1998-03-10 | 2009-02-16 | Genentech, Inc. | Nuevo polipeptido y acidos nucleicos que lo codifican. |
| AU5587799A (en) | 1998-08-27 | 2000-03-21 | Incyte Pharmaceuticals, Inc. | Protein transport-associated molecules |
| KR100468977B1 (ko) | 1998-12-16 | 2005-02-02 | 제넨테크, 인크. | 분비 및 막횡단 폴리펩티드, 및 이를 코딩하는 핵산 |
| DK1140175T3 (da) * | 1998-12-21 | 2006-08-14 | Ludwig Inst Cancer Res | Antistoffer mod trunkeret VEGF-D og anvendelser deraf |
| DK1484338T3 (da) | 1998-12-22 | 2007-06-11 | Genentech Inc | Fremgangsmåder og sammensætninger til inhibition af neoplastisk cellevækst |
| AU3514400A (en) | 1999-03-08 | 2000-09-28 | Genentech Inc. | Compositions and methods for the treatment of immune related diseases |
| PL207994B1 (pl) | 1999-03-11 | 2011-02-28 | Serono Lab | Polipeptyd, skierowane przeciw niemu przeciwciało i ich zastosowanie w medycynie oraz kodujące go poli- lub oligonukleotydy |
| US6642353B1 (en) | 1999-03-17 | 2003-11-04 | Chugai Seiyaku Kabushiki Kaisha | Peptide ligands for the erythropoietin receptor |
| AU2883900A (en) | 1999-07-07 | 2001-01-30 | Genentech Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| WO2001036102A1 (en) | 1999-11-02 | 2001-05-25 | Uliyanovsky Gosudarstvenny Tekhnichesky Universitet | Method for cleaning liquids of ferromagnetic particles and device for the implementation thereof |
| EP1234030A4 (en) | 1999-11-19 | 2003-05-07 | Human Genome Sciences Inc | 18 HUMAN SECRETED PROTEINS |
| CA2496312A1 (en) | 1999-12-01 | 2001-06-07 | Kevin P. Baker | Colon tumour marker pro4799 polypeptides and nucleic acids encoding the same |
| CA2412211A1 (en) | 2000-06-23 | 2002-01-03 | Genetech, Inc. | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
| EP1309685A2 (en) | 2000-07-20 | 2003-05-14 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis |
| AU2003258714A1 (en) | 2002-09-06 | 2004-03-29 | Cytos Biotechnology Ag | Immune modulatory compounds and methods |
| RU2232991C1 (ru) * | 2003-04-09 | 2004-07-20 | Государственное учреждение "Московский научно-исследовательский институт эпидемиологии и микробиологии им. Г.Н. Габричевского" | Способ определения функциональной активности фактора d комплемента человека |
| WO2006071856A2 (en) | 2004-12-23 | 2006-07-06 | Glycofi, Inc. | Immunoglobulins comprising predominantly a man5glcnac2 glycoform |
| NZ567483A (en) * | 2005-11-04 | 2012-04-27 | Genentech Inc | Use of complement pathway inhibitors to treat ocular diseases |
| US20070190057A1 (en) | 2006-01-23 | 2007-08-16 | Jian Wu | Methods for modulating mannose content of recombinant proteins |
| SI2907827T1 (sl) * | 2006-11-02 | 2019-02-28 | Genentech, Inc. | Humanizirana protitelesa proti faktorju D in njihova uporaba |
| AR066660A1 (es) * | 2007-05-23 | 2009-09-02 | Genentech Inc | Prevencion y tratamiento de condiciones del ojo asociadas con su complemento |
| JP4349447B2 (ja) | 2007-07-19 | 2009-10-21 | トヨタ自動車株式会社 | インバータ制御装置および車両 |
-
2008
- 2008-05-21 AR ARP080102150A patent/AR066660A1/es unknown
- 2008-05-22 AU AU2008256835A patent/AU2008256835B2/en not_active Ceased
- 2008-05-22 RS RS20150223A patent/RS53901B1/sr unknown
- 2008-05-22 BR BRPI0811142A patent/BRPI0811142A8/pt not_active Application Discontinuation
- 2008-05-22 DK DK08756130.4T patent/DK2152755T3/en active
- 2008-05-22 KR KR1020097026746A patent/KR101540126B1/ko not_active Expired - Fee Related
- 2008-05-22 ES ES08756130.4T patent/ES2533242T3/es active Active
- 2008-05-22 JP JP2010509554A patent/JP5416695B2/ja not_active Expired - Fee Related
- 2008-05-22 HR HRP20150281AT patent/HRP20150281T1/hr unknown
- 2008-05-22 PT PT87561304T patent/PT2152755E/pt unknown
- 2008-05-22 CN CN201610972614.5A patent/CN107096029B/zh not_active Expired - Fee Related
- 2008-05-22 US US12/154,466 patent/US8007791B2/en not_active Expired - Fee Related
- 2008-05-22 EP EP08756130.4A patent/EP2152755B1/en active Active
- 2008-05-22 CN CN200880100137.7A patent/CN101754980B/zh not_active Expired - Fee Related
- 2008-05-22 PL PL08756130T patent/PL2152755T3/pl unknown
- 2008-05-22 CA CA002683498A patent/CA2683498A1/en not_active Abandoned
- 2008-05-22 WO PCT/US2008/064526 patent/WO2008147883A1/en not_active Ceased
- 2008-05-22 MX MX2009012422A patent/MX2009012422A/es active IP Right Grant
- 2008-05-22 SG SG10201401404RA patent/SG10201401404RA/en unknown
- 2008-05-22 CN CN201410486706.3A patent/CN104367999A/zh active Pending
- 2008-05-22 RU RU2009147744/10A patent/RU2522976C2/ru not_active IP Right Cessation
- 2008-05-22 SI SI200831405T patent/SI2152755T1/sl unknown
- 2008-05-23 TW TW097119194A patent/TWI419704B/zh not_active IP Right Cessation
- 2008-05-23 TW TW102134844A patent/TW201417829A/zh unknown
- 2008-05-23 CL CL2008001498A patent/CL2008001498A1/es unknown
- 2008-05-23 PE PE2008000887A patent/PE20090294A1/es not_active Application Discontinuation
-
2009
- 2009-10-08 ZA ZA2009/07028A patent/ZA200907028B/en unknown
- 2009-10-13 IL IL201476A patent/IL201476A/en active IP Right Grant
-
2011
- 2011-07-22 US US13/189,301 patent/US8268310B2/en not_active Expired - Fee Related
-
2012
- 2012-07-20 US US13/554,787 patent/US8497094B2/en not_active Expired - Fee Related
-
2013
- 2013-05-16 PH PH12013500992A patent/PH12013500992B1/en unknown
- 2013-06-27 US US13/929,167 patent/US20130302333A1/en not_active Abandoned
- 2013-11-15 JP JP2013236445A patent/JP2014087346A/ja not_active Withdrawn
-
2014
- 2014-04-03 RU RU2014113046/10A patent/RU2014113046A/ru not_active Application Discontinuation
-
2015
- 2015-02-27 CY CY20151100205T patent/CY1116062T1/el unknown
- 2015-08-14 HK HK15107851.6A patent/HK1207327A1/xx unknown
-
2016
- 2016-01-29 JP JP2016015288A patent/JP2016145205A/ja not_active Withdrawn
- 2016-02-03 US US15/014,886 patent/US20160272726A1/en not_active Abandoned
- 2016-10-27 IL IL248552A patent/IL248552A0/en unknown
-
2017
- 2017-07-28 JP JP2017146477A patent/JP2017197577A/ja active Pending
- 2017-11-29 US US15/826,016 patent/US20180079826A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010528047A5 (enExample) | ||
| RU2014113046A (ru) | Профилактика и лечение патологических состояний глаз, вызванных комплементом | |
| JP7695187B2 (ja) | ＨＰＴＰ－β（ＶＥ－ＰＴＰ）およびＶＥＧＦを標的にする多特異性抗体 | |
| AU2025271125A1 (en) | Methods for treating or preventing ophthalmological conditions | |
| WO2008154251A4 (en) | C3b antibodies and methods for the prevention and treatment of complement- associated disorders | |
| JP2011504872A5 (enExample) | ||
| JP5990511B2 (ja) | 血管新生に基づく眼障害の処置のための抗ｃｄ１６０特異的抗体 | |
| JP2016504416A5 (enExample) | ||
| US20220162296A1 (en) | Personalized treatment of ophthalmologic diseases | |
| JP2020535184A5 (enExample) | ||
| RU2008144802A (ru) | Применение антител против ил-1 для лечения глазных расстройств | |
| RU2015121755A (ru) | Антагонисты ил-6 и их применение | |
| JP2017535285A5 (enExample) | ||
| JP2015503909A5 (enExample) | ||
| EP2200699A1 (en) | Antigen binding proteins | |
| JP2011503094A5 (enExample) | ||
| JP2017502023A (ja) | 眼疾患を治療する組成物および方法 | |
| JP2018530574A5 (enExample) | ||
| RU2018103960A (ru) | Антитела против ang-2, содержащие только тяжелую цепь | |
| JP2018527327A5 (enExample) | ||
| JP2025114621A (ja) | 神経変性疾患を治療するための改変抗ｐｄ－ｌ１抗体および治療方法および使用 | |
| WO2023001288A1 (zh) | 整合素GPIIb/IIIa拮抗剂及其和抗VEGF抗体联合用药的应用 | |
| JP2018523673A5 (enExample) | ||
| JP7382343B2 (ja) | Ｍｆａｐ４に対する抗体 | |
| JP2021513360A5 (enExample) |