JP2021520195A5 - - Google Patents

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Publication number
JP2021520195A5
JP2021520195A5 JP2020554097A JP2020554097A JP2021520195A5 JP 2021520195 A5 JP2021520195 A5 JP 2021520195A5 JP 2020554097 A JP2020554097 A JP 2020554097A JP 2020554097 A JP2020554097 A JP 2020554097A JP 2021520195 A5 JP2021520195 A5 JP 2021520195A5
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JP
Japan
Prior art keywords
seq
amino acid
acid sequence
sequence described
cdr2
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020554097A
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English (en)
Japanese (ja)
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JP2021520195A (ja
JP7477457B2 (ja
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Priority claimed from PCT/US2019/025123 external-priority patent/WO2019195136A1/en
Publication of JP2021520195A publication Critical patent/JP2021520195A/ja
Publication of JP2021520195A5 publication Critical patent/JP2021520195A5/ja
Priority to JP2024019502A priority Critical patent/JP2024056851A/ja
Application granted granted Critical
Publication of JP7477457B2 publication Critical patent/JP7477457B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020554097A 2018-04-03 2019-04-01 C3結合薬及びその使用方法 Active JP7477457B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024019502A JP2024056851A (ja) 2018-04-03 2024-02-13 C3結合薬及びその使用方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862652253P 2018-04-03 2018-04-03
US62/652,253 2018-04-03
PCT/US2019/025123 WO2019195136A1 (en) 2018-04-03 2019-04-01 C3-binding agents and methods of use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024019502A Division JP2024056851A (ja) 2018-04-03 2024-02-13 C3結合薬及びその使用方法

Publications (3)

Publication Number Publication Date
JP2021520195A JP2021520195A (ja) 2021-08-19
JP2021520195A5 true JP2021520195A5 (enExample) 2022-04-08
JP7477457B2 JP7477457B2 (ja) 2024-05-01

Family

ID=66630340

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020554097A Active JP7477457B2 (ja) 2018-04-03 2019-04-01 C3結合薬及びその使用方法
JP2024019502A Pending JP2024056851A (ja) 2018-04-03 2024-02-13 C3結合薬及びその使用方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024019502A Pending JP2024056851A (ja) 2018-04-03 2024-02-13 C3結合薬及びその使用方法

Country Status (18)

Country Link
US (3) US11136381B2 (enExample)
EP (1) EP3790897A1 (enExample)
JP (2) JP7477457B2 (enExample)
KR (1) KR20200138290A (enExample)
CN (1) CN112105638A (enExample)
AR (1) AR117565A1 (enExample)
AU (1) AU2019248557A1 (enExample)
BR (1) BR112020019907A2 (enExample)
CA (1) CA3093356A1 (enExample)
CL (2) CL2020002522A1 (enExample)
CO (1) CO2020013468A2 (enExample)
IL (1) IL277404A (enExample)
MX (1) MX2020010323A (enExample)
PE (1) PE20212132A1 (enExample)
PH (1) PH12020500664A1 (enExample)
SG (1) SG11202008897SA (enExample)
TW (1) TWI833742B (enExample)
WO (1) WO2019195136A1 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11136381B2 (en) 2018-04-03 2021-10-05 Ngm Biopharmaceuticals, Inc. Anti-C3 antibodies
WO2021226442A2 (en) 2020-05-08 2021-11-11 Ngm Biopharmaceuticals, Inc. Therapeutic uses of c3-binding agents
EP4213808A4 (en) * 2020-09-21 2024-05-22 Apellis Pharmaceuticals, Inc. Methods of treating eye disorders
US20220259296A1 (en) * 2021-02-12 2022-08-18 Boehringer Ingelheim International Gmbh Complement c3 antigen binding proteins
PE20250390A1 (es) * 2021-12-22 2025-02-11 Boehringer Ingelheim Int Anticuerpos anti-c3 y fragmentos de union al antigeno de estos y sus usos para tratar enfermedades oftalmicas u oculares
WO2024086555A1 (en) * 2022-10-17 2024-04-25 Ngm Biopharmaceuticals, Inc. Uses of anti-c3 antibodies
CN117447601B (zh) * 2023-12-22 2024-03-08 北京索莱宝科技有限公司 猪IgM的抗体、抗体组合物及其应用
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof

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JP2002524533A (ja) * 1998-09-10 2002-08-06 ザ ユニヴァーシティー オブ ヴァージニア パテント ファウンデーション 癌細胞に診断薬及び治療薬をデリバリーするためのC3b(i)に対する抗体
AU2003271681A1 (en) 2002-10-04 2004-04-23 Sanquin Blood Supply Foundation Amsterdam Monoclonal antibody anti-c3-2 directed against the third component of complement (c3) and its use in methods to inhibit complement activation
US7816497B2 (en) 2002-10-30 2010-10-19 University Of Kentucky Compositions and methods for inhibiting drusen complement components C3a and C5a for the treatment of age-related macular degeneration
EP1558645B1 (en) * 2002-11-08 2011-07-27 Ablynx N.V. Stabilized single domain antibodies in pharmaceutical composition adapted for inhalation
US20090004183A1 (en) 2004-07-23 2009-01-01 Taylor Ronald P Compositions and Methods for Regulating the Alternative Pathway of Complement
CA2593846A1 (en) 2005-01-14 2006-08-10 The Regents Of The University Of California Compositions and methods for inhibiting drusen formation and for diagnosing or treating drusen-related disorders
US8168584B2 (en) 2005-10-08 2012-05-01 Potentia Pharmaceuticals, Inc. Methods of treating age-related macular degeneration by compstatin and analogs thereof
DK2500030T4 (en) 2005-11-04 2018-10-29 Genentech Inc Use of complement pathway inhibitors for the treatment of eye diseases
EP2148691B1 (en) 2007-02-05 2015-05-20 Apellis Pharmaceuticals, Inc. Compstatin analogues for use in the treatment of inflammatory conditions of the respiratory system
US9745367B2 (en) 2007-03-23 2017-08-29 Novelmed Theraputics, Inc. Alternative pathway specific antibodies for treating arthritis
US8192742B2 (en) 2007-03-23 2012-06-05 NovelMed Therapeutics Method of inhibiting complement activation with human anti-factor C3 antibodies and use thereof
AU2008262048B2 (en) 2007-06-07 2013-09-26 Genentech, Inc. C3b antibodies and methods for the prevention and treatment of complement- associated disorders
US20100291106A1 (en) * 2009-05-06 2010-11-18 Novartis Ag Compositions and methods for antibodies targeting complement protein c3b
AU2010250452B2 (en) 2009-05-20 2014-06-05 Toray Industries, Inc. Cell membrane-permeable peptides
US9291622B2 (en) 2009-05-21 2016-03-22 Apellis Pharmaceuticals, Inc. Complement assays and uses thereof
US20130177567A1 (en) 2010-05-18 2013-07-11 Sydansk Universitet Novel c3c epitope, antibodies binding thereto, and use thereof
BR112012033119A2 (pt) 2010-06-22 2016-10-25 Univ Colorado Regents anticorpos para o fragamento c3d do componente do complemento 3.
AU2013243574B2 (en) * 2012-04-03 2017-12-07 Novelmed Therapeutics, Inc Humanized and chimeric anti-factor C3 antibodies and uses thereof
EP3086809A4 (en) 2013-12-24 2017-11-29 NovelMed Therapeutics, Inc. Compositions and methods of treating ocular diseases
MX2016014504A (es) 2014-05-05 2017-05-23 Regeneron Pharma Animales c5 y c3 humanizados.
US10815276B2 (en) 2014-05-21 2020-10-27 Entrada Therapeutics, Inc. Cell penetrating peptides and methods of making and using thereof
WO2016094679A1 (en) * 2014-12-10 2016-06-16 Regents Of The University Of Minnesota Genetically modified cells, tissues, and organs for treating disease
US20180346531A1 (en) 2015-09-15 2018-12-06 Regents Of The University Of California Compositions and methods for delivering biotherapeutics
KR20180090785A (ko) 2015-10-07 2018-08-13 아펠리스 파마슈티컬스 인코포레이티드 투여 요법
RU2630647C1 (ru) * 2016-05-27 2017-09-11 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт особо чистых биопрепаратов" Федерального медико-биологического агентства ГУМАНИЗИРОВАННОЕ АНТИТЕЛО К КОНФОРМАЦИОННОМУ ЭПИТОПУ С3 КОМПОНЕНТА КОМПЛЕМЕНТА ЧЕЛОВЕКА, ПОСЛЕДОВАТЕЛЬНОСТЬ ДНК (ВАРИАНТЫ), ЭКСПРЕССИОННЫЙ ВЕКТОР, СОДЕРЖАЩИЙ ПОСЛЕДОВАТЕЛЬНОСТЬ ДНК (ВАРИАНТЫ), И ШТАММ КЛЕТОК ЯИЧНИКОВ КИТАЙСКОГО ХОМЯЧКА CHO-humC34-ПРОДУЦЕНТ ДАННОГО ГУМАНИЗИРОВАННОГО АНТИТЕЛА
US10905770B2 (en) 2017-07-17 2021-02-02 Macregen, Inc. Topical delivery of therapeutic agents using cell-penetrating peptides for the treatment of age-related macular degeneration and other eye diseases
US11136381B2 (en) 2018-04-03 2021-10-05 Ngm Biopharmaceuticals, Inc. Anti-C3 antibodies

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