JP2021520195A5 - - Google Patents

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Publication number
JP2021520195A5
JP2021520195A5 JP2020554097A JP2020554097A JP2021520195A5 JP 2021520195 A5 JP2021520195 A5 JP 2021520195A5 JP 2020554097 A JP2020554097 A JP 2020554097A JP 2020554097 A JP2020554097 A JP 2020554097A JP 2021520195 A5 JP2021520195 A5 JP 2021520195A5
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JP
Japan
Prior art keywords
seq
amino acid
acid sequence
sequence described
cdr2
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JP2020554097A
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English (en)
Japanese (ja)
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JP7477457B2 (ja
JP2021520195A (ja
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Priority claimed from PCT/US2019/025123 external-priority patent/WO2019195136A1/en
Publication of JP2021520195A publication Critical patent/JP2021520195A/ja
Publication of JP2021520195A5 publication Critical patent/JP2021520195A5/ja
Priority to JP2024019502A priority Critical patent/JP2024056851A/ja
Application granted granted Critical
Publication of JP7477457B2 publication Critical patent/JP7477457B2/ja
Active legal-status Critical Current
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JP2020554097A 2018-04-03 2019-04-01 C3結合薬及びその使用方法 Active JP7477457B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024019502A JP2024056851A (ja) 2018-04-03 2024-02-13 C3結合薬及びその使用方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862652253P 2018-04-03 2018-04-03
US62/652,253 2018-04-03
PCT/US2019/025123 WO2019195136A1 (en) 2018-04-03 2019-04-01 C3-binding agents and methods of use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024019502A Division JP2024056851A (ja) 2018-04-03 2024-02-13 C3結合薬及びその使用方法

Publications (3)

Publication Number Publication Date
JP2021520195A JP2021520195A (ja) 2021-08-19
JP2021520195A5 true JP2021520195A5 (enExample) 2022-04-08
JP7477457B2 JP7477457B2 (ja) 2024-05-01

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ID=66630340

Family Applications (2)

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JP2020554097A Active JP7477457B2 (ja) 2018-04-03 2019-04-01 C3結合薬及びその使用方法
JP2024019502A Pending JP2024056851A (ja) 2018-04-03 2024-02-13 C3結合薬及びその使用方法

Family Applications After (1)

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JP2024019502A Pending JP2024056851A (ja) 2018-04-03 2024-02-13 C3結合薬及びその使用方法

Country Status (18)

Country Link
US (3) US11136381B2 (enExample)
EP (1) EP3790897A1 (enExample)
JP (2) JP7477457B2 (enExample)
KR (1) KR20200138290A (enExample)
CN (1) CN112105638A (enExample)
AR (1) AR117565A1 (enExample)
AU (1) AU2019248557A1 (enExample)
BR (1) BR112020019907A2 (enExample)
CA (1) CA3093356A1 (enExample)
CL (2) CL2020002522A1 (enExample)
CO (1) CO2020013468A2 (enExample)
IL (1) IL277404A (enExample)
MX (1) MX2020010323A (enExample)
PE (1) PE20212132A1 (enExample)
PH (1) PH12020500664A1 (enExample)
SG (1) SG11202008897SA (enExample)
TW (1) TWI833742B (enExample)
WO (1) WO2019195136A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7477457B2 (ja) 2018-04-03 2024-05-01 エヌジーエム バイオファーマシューティカルス,インコーポレーテッド C3結合薬及びその使用方法
WO2021226442A2 (en) 2020-05-08 2021-11-11 Ngm Biopharmaceuticals, Inc. Therapeutic uses of c3-binding agents
EP4213808A4 (en) * 2020-09-21 2024-05-22 Apellis Pharmaceuticals, Inc. Methods of treating eye disorders
WO2022171771A1 (en) * 2021-02-12 2022-08-18 Boehringer Ingelheim International Gmbh Complement c3 antigen binding proteins
CR20240265A (es) 2021-12-22 2024-10-16 Boehringer Ingelheim Int Anticuerpos anti-c3 y fragmentos de unión al antígeno de estos y sus usos para tratar enfermedades oftálmicas u oculares
WO2024086555A1 (en) * 2022-10-17 2024-04-25 Ngm Biopharmaceuticals, Inc. Uses of anti-c3 antibodies
CN117447601B (zh) * 2023-12-22 2024-03-08 北京索莱宝科技有限公司 猪IgM的抗体、抗体组合物及其应用
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof

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MXPA01002580A (es) * 1998-09-10 2002-04-08 Univ Virginia Anticuerpos para c3b(1) para el suministro de agentes de diagnostico y terapeuticos para celulas cancerosas.
WO2004031240A1 (en) * 2002-10-04 2004-04-15 Stichting Sanquin Bloedvoorziening Monoclonal antibody anti-c3-2 directed against the third component of complement (c3) and its use in methods to inhibit complement activation
US7816497B2 (en) 2002-10-30 2010-10-19 University Of Kentucky Compositions and methods for inhibiting drusen complement components C3a and C5a for the treatment of age-related macular degeneration
EP1558645B1 (en) * 2002-11-08 2011-07-27 Ablynx N.V. Stabilized single domain antibodies in pharmaceutical composition adapted for inhalation
US20090004183A1 (en) 2004-07-23 2009-01-01 Taylor Ronald P Compositions and Methods for Regulating the Alternative Pathway of Complement
CA2593846A1 (en) 2005-01-14 2006-08-10 The Regents Of The University Of California Compositions and methods for inhibiting drusen formation and for diagnosing or treating drusen-related disorders
US8168584B2 (en) 2005-10-08 2012-05-01 Potentia Pharmaceuticals, Inc. Methods of treating age-related macular degeneration by compstatin and analogs thereof
SG10201804008UA (en) 2005-11-04 2018-06-28 Genentech Inc Use of complement pathway inhibitors to treat ocular diseases
HUE026001T2 (en) 2007-02-05 2016-04-28 Apellis Pharmaceuticals Inc Compstatin analogues for use in the treatment of the inflammatory condition of the respiratory system
US8192742B2 (en) 2007-03-23 2012-06-05 NovelMed Therapeutics Method of inhibiting complement activation with human anti-factor C3 antibodies and use thereof
US9745367B2 (en) 2007-03-23 2017-08-29 Novelmed Theraputics, Inc. Alternative pathway specific antibodies for treating arthritis
RU2473563C2 (ru) 2007-06-07 2013-01-27 Дженентек, Инк. АНТИТЕЛА ПРОТИВ C3b И СПОСОБЫ ПРОФИЛАКТИКИ И ЛЕЧЕНИЯ СВЯЗАННЫХ С КОМПЛЕМЕНТОМ НАРУШЕНИЙ
US20100291106A1 (en) * 2009-05-06 2010-11-18 Novartis Ag Compositions and methods for antibodies targeting complement protein c3b
RU2548807C2 (ru) 2009-05-20 2015-04-20 Торэй Индастриз, Инк. Пептиды, проникающие в клетку
WO2010135717A2 (en) 2009-05-21 2010-11-25 Potentia Pharmaceuticals, Inc. Complement assays and uses thereof
US20130177567A1 (en) 2010-05-18 2013-07-11 Sydansk Universitet Novel c3c epitope, antibodies binding thereto, and use thereof
SG186397A1 (en) 2010-06-22 2013-01-30 Univ Colorado Regents Antibodies to the c3d fragment of complement component 3
CA2869477C (en) * 2012-04-03 2020-06-09 Novelmed Therapeutics, Inc. Humanized and chimeric anti-factor c3 antibodies and uses thereof
AU2014370404A1 (en) 2013-12-24 2016-07-07 Novelmed Therapeutics, Inc. Compositions and methods of treating ocular diseases
EP3636073B1 (en) 2014-05-05 2023-11-15 Regeneron Pharmaceuticals, Inc. Humanized c5 and c3 animals
US10815276B2 (en) 2014-05-21 2020-10-27 Entrada Therapeutics, Inc. Cell penetrating peptides and methods of making and using thereof
CN116059378A (zh) * 2014-12-10 2023-05-05 明尼苏达大学董事会 用于治疗疾病的遗传修饰的细胞、组织和器官
WO2017048466A1 (en) 2015-09-15 2017-03-23 The Regents Of The University Of California Compositions and methods for delivering biotherapeutics
US11903994B2 (en) 2015-10-07 2024-02-20 Apellis Pharmaceuticals, Inc. Dosing regimens
RU2630647C1 (ru) * 2016-05-27 2017-09-11 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт особо чистых биопрепаратов" Федерального медико-биологического агентства ГУМАНИЗИРОВАННОЕ АНТИТЕЛО К КОНФОРМАЦИОННОМУ ЭПИТОПУ С3 КОМПОНЕНТА КОМПЛЕМЕНТА ЧЕЛОВЕКА, ПОСЛЕДОВАТЕЛЬНОСТЬ ДНК (ВАРИАНТЫ), ЭКСПРЕССИОННЫЙ ВЕКТОР, СОДЕРЖАЩИЙ ПОСЛЕДОВАТЕЛЬНОСТЬ ДНК (ВАРИАНТЫ), И ШТАММ КЛЕТОК ЯИЧНИКОВ КИТАЙСКОГО ХОМЯЧКА CHO-humC34-ПРОДУЦЕНТ ДАННОГО ГУМАНИЗИРОВАННОГО АНТИТЕЛА
JP2020528082A (ja) 2017-07-17 2020-09-17 ロイズマン,キース 加齢黄斑変性と他の眼疾患の治療用の細胞透過性ペプチドを使用する治療薬の局所送達
JP7477457B2 (ja) 2018-04-03 2024-05-01 エヌジーエム バイオファーマシューティカルス,インコーポレーテッド C3結合薬及びその使用方法

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