JP2015527364A5 - - Google Patents
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- JP2015527364A5 JP2015527364A5 JP2015528576A JP2015528576A JP2015527364A5 JP 2015527364 A5 JP2015527364 A5 JP 2015527364A5 JP 2015528576 A JP2015528576 A JP 2015528576A JP 2015528576 A JP2015528576 A JP 2015528576A JP 2015527364 A5 JP2015527364 A5 JP 2015527364A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- antibody
- antigen
- binding fragment
- asthma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261691625P | 2012-08-21 | 2012-08-21 | |
| US61/691,625 | 2012-08-21 | ||
| US201361758097P | 2013-01-29 | 2013-01-29 | |
| US61/758,097 | 2013-01-29 | ||
| US201361761279P | 2013-02-06 | 2013-02-06 | |
| US61/761,279 | 2013-02-06 | ||
| US201361783796P | 2013-03-14 | 2013-03-14 | |
| US61/783,796 | 2013-03-14 | ||
| US201361805797P | 2013-03-27 | 2013-03-27 | |
| US61/805,797 | 2013-03-27 | ||
| FR1356994 | 2013-07-16 | ||
| FR1356994 | 2013-07-16 | ||
| PCT/US2013/055747 WO2014031610A1 (en) | 2012-08-21 | 2013-08-20 | Methods for treating or preventing asthma by administering an il-4r antagonist |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018040279A Division JP2018109056A (ja) | 2012-08-21 | 2018-03-07 | Ｉｌ−４ｒアンタゴニストを投与することにより喘息を処置又は予防するための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015527364A JP2015527364A (ja) | 2015-09-17 |
| JP2015527364A5 true JP2015527364A5 (enExample) | 2016-09-29 |
| JP6306588B2 JP6306588B2 (ja) | 2018-04-04 |
Family
ID=50148186
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015528576A Active JP6306588B2 (ja) | 2012-08-21 | 2013-08-20 | Ｉｌ−４ｒアンタゴニストを投与することにより喘息を処置又は予防するための方法 |
| JP2018040279A Pending JP2018109056A (ja) | 2012-08-21 | 2018-03-07 | Ｉｌ−４ｒアンタゴニストを投与することにより喘息を処置又は予防するための方法 |
| JP2023005561A Active JP7609901B2 (ja) | 2012-08-21 | 2023-01-18 | Ｉｌ－４ｒアンタゴニストを投与することにより喘息を処置又は予防するための方法 |
| JP2024221236A Pending JP2025038127A (ja) | 2012-08-21 | 2024-12-18 | Ｉｌ－４ｒアンタゴニストを投与することにより喘息を処置又は予防するための方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018040279A Pending JP2018109056A (ja) | 2012-08-21 | 2018-03-07 | Ｉｌ−４ｒアンタゴニストを投与することにより喘息を処置又は予防するための方法 |
| JP2023005561A Active JP7609901B2 (ja) | 2012-08-21 | 2023-01-18 | Ｉｌ－４ｒアンタゴニストを投与することにより喘息を処置又は予防するための方法 |
| JP2024221236A Pending JP2025038127A (ja) | 2012-08-21 | 2024-12-18 | Ｉｌ－４ｒアンタゴニストを投与することにより喘息を処置又は予防するための方法 |
Country Status (28)
| Country | Link |
|---|---|
| US (4) | US9574004B2 (enExample) |
| EP (4) | EP4324479A3 (enExample) |
| JP (4) | JP6306588B2 (enExample) |
| KR (6) | KR102502640B1 (enExample) |
| CN (2) | CN104755495A (enExample) |
| AR (1) | AR092177A1 (enExample) |
| AU (4) | AU2013305945B2 (enExample) |
| BR (1) | BR112015003590A8 (enExample) |
| CA (1) | CA2882416A1 (enExample) |
| DK (1) | DK2888281T3 (enExample) |
| ES (3) | ES2900342T3 (enExample) |
| HR (1) | HRP20181963T1 (enExample) |
| HU (1) | HUE064945T2 (enExample) |
| IL (3) | IL312711A (enExample) |
| IN (1) | IN2015KN00414A (enExample) |
| LT (1) | LT2888281T (enExample) |
| MX (1) | MX371344B (enExample) |
| NZ (3) | NZ631562A (enExample) |
| PL (3) | PL3470432T3 (enExample) |
| PT (2) | PT4011915T (enExample) |
| PY (1) | PY1337526A (enExample) |
| RS (1) | RS58091B1 (enExample) |
| RU (1) | RU2690675C2 (enExample) |
| SG (2) | SG11201500889TA (enExample) |
| SI (1) | SI2888281T1 (enExample) |
| TW (1) | TWI656880B (enExample) |
| UY (1) | UY34984A (enExample) |
| WO (1) | WO2014031610A1 (enExample) |
Families Citing this family (56)
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|---|---|---|---|---|
| US7608693B2 (en) | 2006-10-02 | 2009-10-27 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human IL-4 receptor |
| PL2624865T3 (pl) | 2010-10-06 | 2018-11-30 | Regeneron Pharmaceuticals, Inc. | Stabilizowane preparaty zawierające przeciwciała przeciwko receptorowi interleukiny-4 (IL-4R) |
| TR201819492T4 (tr) * | 2012-08-21 | 2019-01-21 | Regeneron Pharma | Bir ıl-4r antagonisti uygulayarak astımı tedavi etmek veya önlemek için yöntemler. |
| WO2014031610A1 (en) | 2012-08-21 | 2014-02-27 | Sanofi | Methods for treating or preventing asthma by administering an il-4r antagonist |
| HRP20181227T1 (hr) | 2012-09-07 | 2018-10-05 | Regeneron Pharmaceuticals, Inc. | Metode za liječenje atopijskog dermatitisa primjenom antagonista il-4r |
| TWI755763B (zh) | 2013-06-04 | 2022-02-21 | 美商再生元醫藥公司 | 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法 |
| TWI634900B (zh) | 2013-07-11 | 2018-09-11 | 再生元醫藥公司 | 藉由投與ｉｌ－４ｒ抑制劑治療嗜酸性食道炎的方法 |
| EP3725311A1 (en) | 2014-02-10 | 2020-10-21 | Respivant Sciences GmbH | Methods for the treatment of lung diseases with mast cell stabilizers |
| EP3653207A1 (en) | 2014-02-10 | 2020-05-20 | Respivant Sciences GmbH | Mast cell stabilizers treatment for systemic disorders |
| IL247290B (en) * | 2014-02-21 | 2021-06-30 | Sanofi Biotechnology | Methods of treating or preventing asthma by adding an il-4r antagonist |
| IL315136A (en) * | 2014-02-21 | 2024-10-01 | Sanofi Biotechnology | Methods for treating or preventing asthma by administering an il-4rantagonist |
| RU2704999C2 (ru) | 2014-02-28 | 2019-11-01 | Ридженерон Фармасьютикалз, Инк. | Способ лечения кожной инфекции путем введения антагониста il-4r |
| PT3613432T (pt) | 2014-05-07 | 2025-10-29 | Regeneron Pharma | Métodos para tratar a polipose nasal através da administração de um antagonista de il-4r |
| NO2785538T3 (enExample) * | 2014-05-07 | 2018-08-04 | ||
| TWI745962B (zh) * | 2014-06-27 | 2021-11-11 | 法商賽諾菲公司 | 測定投予至人類個體之包括雙-v-區類抗體蛋白或其片段的劑量是否在人類個體中與il-4或il-13特異性結合之方法 |
| MA40164A (fr) * | 2014-06-27 | 2017-05-03 | Sanofi Sa | Anticorps bispécifiques anti-il4-il13 |
| US10066017B2 (en) | 2014-11-14 | 2018-09-04 | Sanofi Biotechnology | Methods for treating chronic sinusitis with nasal polyps by administering an IL-4R antagonist |
| NZ731954A (en) | 2014-12-09 | 2024-11-29 | Regeneron Pharma | Non-human animals having a humanized cluster of differentiation 274 gene |
| EP3331522A1 (en) | 2015-08-07 | 2018-06-13 | Patara Pharma LLC | Methods for the treatment of mast cell related disorders with mast cell stabilizers |
| US10265296B2 (en) | 2015-08-07 | 2019-04-23 | Respivant Sciences Gmbh | Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders |
| CN107474134B (zh) | 2016-06-08 | 2021-07-27 | 苏州康乃德生物医药有限公司 | 用于结合白细胞介素4受体的抗体 |
| CN110139646A (zh) | 2016-08-31 | 2019-08-16 | 瑞思皮万特科学有限责任公司 | 用于治疗由特发性肺纤维化引起的慢性咳嗽的色甘酸组合物 |
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| CN109789196B (zh) * | 2016-09-01 | 2024-03-19 | 瑞泽恩制药公司 | 用于通过施用il-4r拮抗剂来预防或治疗变态反应的方法 |
| WO2018067341A1 (en) | 2016-10-07 | 2018-04-12 | Patara Pharma, LLC | Cromolyn compositions for treatment of pulmonary fibrosis |
| CN110062765A (zh) * | 2016-10-31 | 2019-07-26 | 维克特拉有限公司 | 包括il-13抗体的可吸入粉末组合物 |
| TWI857389B (zh) * | 2016-12-01 | 2024-10-01 | 美商再生元醫藥公司 | 治療發炎症狀的方法 |
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| BR112019021812A2 (pt) * | 2017-04-21 | 2020-05-26 | Kindred Biosciences, Inc. | Molécula receptora de il4/il13 para uso veterinário |
| WO2019028367A1 (en) | 2017-08-04 | 2019-02-07 | Regeneron Pharmaceuticals, Inc. | METHODS OF TREATING ESOPHAGITIS WITH ACTIVE EOSINOPHILES |
| PT3515465T (pt) | 2017-08-18 | 2024-03-04 | Regeneron Pharma | Métodos para o tratamento de uma dermatite atópica grave mediante a administração de um inibidor de il-4r |
| PL3703818T3 (pl) * | 2017-10-30 | 2024-03-25 | Sanofi Biotechnology | Antagonista IL-4R do zastosowania w sposobie leczenia lub zapobiegania astmie |
| WO2019097534A1 (en) * | 2017-11-15 | 2019-05-23 | Venkata Satya Suresh Attili | A device and method to determine the mean/average control of asthma/copd over time and compliance to treatment |
| EP3793597A1 (en) | 2018-05-13 | 2021-03-24 | Regeneron Pharmaceuticals, Inc. | Methods for treating atopic dermatitis by administering an il-4r inhibitor |
| BR112021002989A2 (pt) | 2018-08-24 | 2021-05-11 | Jiangsu Hengrui Medicine Co., Ltd. | anticorpo para ligação de il-4r de humano, fragmento para ligação de antígeno e uso médico do mesmo |
| CN110872349A (zh) | 2018-09-04 | 2020-03-10 | 三生国健药业（上海）股份有限公司 | 结合人il-4r的抗体、其制备方法和用途 |
| WO2020074005A1 (en) | 2018-10-12 | 2020-04-16 | Beijing Biocytogen Co., Ltd | Genetically modified non-human animal with human or chimeric genes |
| WO2020086886A1 (en) | 2018-10-25 | 2020-04-30 | Kindred Biosciences, Inc. | Il4/il13 receptor molecule for veterinary use |
| CN111494625B (zh) | 2018-12-25 | 2022-06-21 | 江苏荃信生物医药股份有限公司 | 用于治疗il-4和/或il-13介导的信号转导相关的疾病的药物组合物 |
| CN111647082B (zh) * | 2018-12-27 | 2023-02-17 | 中山康方生物医药有限公司 | 抗人il-4ra的抗体及其用途 |
| SG11202109003QA (en) * | 2019-03-06 | 2021-09-29 | Regeneron Pharma | Il-4/il-13 pathway inhibitors for enhanced efficacy in treating cancer |
| MA55372A (fr) | 2019-03-21 | 2022-01-26 | Regeneron Pharma | Combinaison d'inhibiteurs de la voie il-4/il-13 et d'ablation de plasmocytes pour traiter une allergie |
| BR112021021195A2 (pt) * | 2019-05-01 | 2022-03-03 | Regeneron Pharma | Métodos para tratamento ou prevenção da asma pela administração de um antagonista de il-33 |
| CN112010977B (zh) | 2019-05-29 | 2022-04-26 | 山东博安生物技术股份有限公司 | 抗白介素4受体(il-4r)的抗体及其应用 |
| JP7592064B2 (ja) | 2019-07-16 | 2024-11-29 | サノフィ・バイオテクノロジー | Ｉｌ－４ｒアンタゴニストを投与することにより喘息を治療するまたは予防するための方法 |
| AU2020326713A1 (en) | 2019-08-05 | 2022-02-17 | Regeneron Pharmaceuticals, Inc. | Methods for treating atopic dermatitis by administering an il-4r antagonist |
| CN114173819A (zh) | 2019-08-05 | 2022-03-11 | 瑞泽恩制药公司 | 通过施用il-4r拮抗剂治疗过敏和增强过敏原特异性免疫疗法的方法 |
| EP3992974A1 (en) | 2020-11-02 | 2022-05-04 | Sanofi Biotechnology | Methods for treating digitally-identified il-4/il-13 related disorders |
| EP4073810A1 (en) | 2019-12-09 | 2022-10-19 | Sanofi Biotechnology | Methods for treating digitally-identified il-4/il-13 related disorders |
| AU2021223128A1 (en) | 2020-02-21 | 2022-09-08 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | Pharmaceutical composition containing anti-IL-4R antibody and use thereof |
| CN113527485B (zh) * | 2020-04-17 | 2024-11-15 | 湖南麦济生物技术股份有限公司 | 抗人白细胞介素-4受体α抗体及其制备方法和应用 |
| CN111690066B (zh) * | 2020-06-22 | 2022-07-22 | 南京融捷康生物科技有限公司 | 抗IL-4Rα的单域抗体以及应用和药物 |
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