RU2690675C2 - Способы лечения или предотвращения астмы посредством введения антагониста il-4r - Google Patents

Способы лечения или предотвращения астмы посредством введения антагониста il-4r Download PDF

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RU2690675C2
RU2690675C2 RU2015109716A RU2015109716A RU2690675C2 RU 2690675 C2 RU2690675 C2 RU 2690675C2 RU 2015109716 A RU2015109716 A RU 2015109716A RU 2015109716 A RU2015109716 A RU 2015109716A RU 2690675 C2 RU2690675 C2 RU 2690675C2
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antigen
antibody
asthma
binding fragment
dose
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RU2015109716A
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Russian (ru)
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RU2015109716A (ru
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Мариус АРДЕЛЕАНУ
Намита ГАНДХИ
Нейл ГРЭХЕМ
Стефан К. КИРКЕССЕЛИ
Судип Кунду
Аллен РЕЙДИН
Росс Э. РОКЛИН
Стивен ВАЙНШТЕЙН
ХЭМИЛТОН Дженнифер ДЭВИДСОН
Джеффри МИНГ
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Санофи Байотекнолоджи
Ридженерон Фармасьютикалз Инк.
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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    • C07K16/244—Interleukins [IL]
    • C07K16/247—IL-4
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    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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RU2015109716A 2012-08-21 2013-08-20 Способы лечения или предотвращения астмы посредством введения антагониста il-4r RU2690675C2 (ru)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US201261691625P 2012-08-21 2012-08-21
US61/691,625 2012-08-21
US201361758097P 2013-01-29 2013-01-29
US61/758,097 2013-01-29
US201361761279P 2013-02-06 2013-02-06
US61/761,279 2013-02-06
US201361783796P 2013-03-14 2013-03-14
US61/783,796 2013-03-14
US201361805797P 2013-03-27 2013-03-27
US61/805,797 2013-03-27
FR1356994 2013-07-16
FR1356994 2013-07-16
PCT/US2013/055747 WO2014031610A1 (en) 2012-08-21 2013-08-20 Methods for treating or preventing asthma by administering an il-4r antagonist

Related Child Applications (1)

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RU2018128137A Division RU2801531C2 (ru) 2012-08-21 2013-08-20 Способы лечения или предотвращения астмы посредством введения антагониста il-4r

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RU2015109716A RU2015109716A (ru) 2016-10-10
RU2690675C2 true RU2690675C2 (ru) 2019-06-05

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US (3) US9574004B2 (enExample)
EP (4) EP4324479A3 (enExample)
JP (4) JP6306588B2 (enExample)
KR (6) KR102679182B1 (enExample)
CN (2) CN110624107A (enExample)
AR (1) AR092177A1 (enExample)
AU (4) AU2013305945B2 (enExample)
BR (1) BR112015003590A8 (enExample)
CA (1) CA2882416A1 (enExample)
DK (1) DK2888281T3 (enExample)
ES (3) ES2900342T3 (enExample)
HR (1) HRP20181963T1 (enExample)
HU (1) HUE064945T2 (enExample)
IL (3) IL312711A (enExample)
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LT (1) LT2888281T (enExample)
MX (1) MX371344B (enExample)
NZ (3) NZ783258A (enExample)
PL (3) PL3470432T3 (enExample)
PT (2) PT4011915T (enExample)
RS (1) RS58091B1 (enExample)
RU (1) RU2690675C2 (enExample)
SG (2) SG10201701331SA (enExample)
SI (1) SI2888281T1 (enExample)
TW (1) TWI656880B (enExample)
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WO (1) WO2014031610A1 (enExample)

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HUE042117T2 (hu) * 2012-08-21 2019-06-28 Sanofi Biotechnology Eljárások asztma kezelésére vagy megelõzésére IL-4R antagonista beadásával
PT4011915T (pt) 2012-08-21 2024-01-02 Regeneron Pharma Métodos para o tratamento ou prevenção da asma através da administração de um antagonista de il-4r
LT2892927T (lt) 2012-09-07 2018-09-10 Regeneron Pharmaceuticals, Inc. Atopinio dermatito gydymo būdai, skiriant il-4r antagonistą
TWI755763B (zh) 2013-06-04 2022-02-21 美商再生元醫藥公司 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法
SG10201710557QA (en) 2013-06-21 2018-01-30 Sanofi Biotechnology Methods for treating nasal polyposis by administering an il-4r antagonist
TWI634900B (zh) 2013-07-11 2018-09-11 再生元醫藥公司 藉由投與ｉｌ－４ｒ抑制劑治療嗜酸性食道炎的方法
AU2015213678C1 (en) 2014-02-10 2019-03-21 Respivant Sciences Gmbh Mast cell stabilizers treatment for systemic disorders
EP3725311A1 (en) 2014-02-10 2020-10-21 Respivant Sciences GmbH Methods for the treatment of lung diseases with mast cell stabilizers
IL247290B (en) * 2014-02-21 2021-06-30 Sanofi Biotechnology Methods of treating or preventing asthma by adding an il-4r antagonist
IL315136A (en) 2014-02-21 2024-10-01 Sanofi Biotechnology Methods for treating or preventing asthma by administering an il-4rantagonist
EP4353254A3 (en) 2014-02-28 2024-07-03 Regeneron Pharmaceuticals, Inc. Methods for treating skin infection by administering an il-4r antagonist
NO2785538T3 (enExample) * 2014-05-07 2018-08-04
TW201628647A (zh) 2014-06-27 2016-08-16 賽諾菲公司 抗－ｉｌ４－ｉｌ１３雙特異性抗體
MA40164A (fr) * 2014-06-27 2017-05-03 Sanofi Sa Anticorps bispécifiques anti-il4-il13
MX2017006286A (es) 2014-11-14 2018-01-23 Sanofi Biotechnology Metodos para tratar sinusitis cronica con polipos nasales por administracion de un antagonista de il-4r.
SMT202400313T1 (it) 2014-12-09 2024-09-16 Regeneron Pharma Animali non umani aventi un cluster umanizzato di un gene di differenziazione 274
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US10238625B2 (en) 2015-08-07 2019-03-26 Respivant Sciences Gmbh Methods for the treatment of mast cell related disorders with mast cell stabilizers
CN107474134B (zh) 2016-06-08 2021-07-27 苏州康乃德生物医药有限公司 用于结合白细胞介素4受体的抗体
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AU2020277207A1 (en) 2020-12-24
UY34984A (es) 2014-03-31
TWI656880B (zh) 2019-04-21
AU2018253544A1 (en) 2018-11-22
HK1211605A1 (en) 2016-05-27
EP2888281B1 (en) 2018-09-19
MX371344B (es) 2020-01-27
EP4011915B8 (en) 2023-11-15
TW201420116A (zh) 2014-06-01
IL293398A (en) 2022-07-01
IN2015KN00414A (enExample) 2015-07-17
JP2015527364A (ja) 2015-09-17

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