KR20250099415A - Il-4r 길항제의 투여에 의한 천식의 치료 또는 예방 방법 - Google Patents
Il-4r 길항제의 투여에 의한 천식의 치료 또는 예방 방법 Download PDFInfo
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- KR20250099415A KR20250099415A KR1020257021022A KR20257021022A KR20250099415A KR 20250099415 A KR20250099415 A KR 20250099415A KR 1020257021022 A KR1020257021022 A KR 1020257021022A KR 20257021022 A KR20257021022 A KR 20257021022A KR 20250099415 A KR20250099415 A KR 20250099415A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/247—IL-4
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- A—HUMAN NECESSITIES
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
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- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Mycology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
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Applications Claiming Priority (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261691625P | 2012-08-21 | 2012-08-21 | |
| US61/691,625 | 2012-08-21 | ||
| US201361758097P | 2013-01-29 | 2013-01-29 | |
| US61/758,097 | 2013-01-29 | ||
| US201361761279P | 2013-02-06 | 2013-02-06 | |
| US61/761,279 | 2013-02-06 | ||
| US201361783796P | 2013-03-14 | 2013-03-14 | |
| US61/783,796 | 2013-03-14 | ||
| US201361805797P | 2013-03-27 | 2013-03-27 | |
| US61/805,797 | 2013-03-27 | ||
| FR1356994 | 2013-07-16 | ||
| FR1356994 | 2013-07-16 | ||
| KR1020247021031A KR20240101727A (ko) | 2012-08-21 | 2013-08-20 | Il-4r 길항제의 투여에 의한 천식의 치료 또는 예방 방법 |
| PCT/US2013/055747 WO2014031610A1 (en) | 2012-08-21 | 2013-08-20 | Methods for treating or preventing asthma by administering an il-4r antagonist |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020247021031A Division KR20240101727A (ko) | 2012-08-21 | 2013-08-20 | Il-4r 길항제의 투여에 의한 천식의 치료 또는 예방 방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20250099415A true KR20250099415A (ko) | 2025-07-01 |
Family
ID=50148186
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020257021022A Pending KR20250099415A (ko) | 2012-08-21 | 2013-08-20 | Il-4r 길항제의 투여에 의한 천식의 치료 또는 예방 방법 |
| KR1020217030423A Active KR102386304B1 (ko) | 2012-08-21 | 2013-08-20 | Il-4r 길항제의 투여에 의한 천식의 치료 또는 예방 방법 |
| KR1020247021031A Ceased KR20240101727A (ko) | 2012-08-21 | 2013-08-20 | Il-4r 길항제의 투여에 의한 천식의 치료 또는 예방 방법 |
| KR1020157005821A Active KR102307248B1 (ko) | 2012-08-21 | 2013-08-20 | Il-4r 길항제의 투여에 의한 천식의 치료 또는 예방 방법 |
| KR1020237005762A Active KR102679182B1 (ko) | 2012-08-21 | 2013-08-20 | Il-4r 길항제의 투여에 의한 천식의 치료 또는 예방 방법 |
| KR1020227011842A Active KR102502640B1 (ko) | 2012-08-21 | 2013-08-20 | Il-4r 길항제의 투여에 의한 천식의 치료 또는 예방 방법 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020217030423A Active KR102386304B1 (ko) | 2012-08-21 | 2013-08-20 | Il-4r 길항제의 투여에 의한 천식의 치료 또는 예방 방법 |
| KR1020247021031A Ceased KR20240101727A (ko) | 2012-08-21 | 2013-08-20 | Il-4r 길항제의 투여에 의한 천식의 치료 또는 예방 방법 |
| KR1020157005821A Active KR102307248B1 (ko) | 2012-08-21 | 2013-08-20 | Il-4r 길항제의 투여에 의한 천식의 치료 또는 예방 방법 |
| KR1020237005762A Active KR102679182B1 (ko) | 2012-08-21 | 2013-08-20 | Il-4r 길항제의 투여에 의한 천식의 치료 또는 예방 방법 |
| KR1020227011842A Active KR102502640B1 (ko) | 2012-08-21 | 2013-08-20 | Il-4r 길항제의 투여에 의한 천식의 치료 또는 예방 방법 |
Country Status (27)
| Country | Link |
|---|---|
| US (3) | US9574004B2 (enExample) |
| EP (4) | EP4011915B8 (enExample) |
| JP (4) | JP6306588B2 (enExample) |
| KR (6) | KR20250099415A (enExample) |
| CN (2) | CN104755495A (enExample) |
| AR (1) | AR092177A1 (enExample) |
| AU (4) | AU2013305945B2 (enExample) |
| BR (1) | BR112015003590A8 (enExample) |
| CA (1) | CA2882416A1 (enExample) |
| DK (1) | DK2888281T3 (enExample) |
| ES (3) | ES2971088T3 (enExample) |
| HR (1) | HRP20181963T1 (enExample) |
| HU (1) | HUE064945T2 (enExample) |
| IL (3) | IL293398B2 (enExample) |
| IN (1) | IN2015KN00414A (enExample) |
| LT (1) | LT2888281T (enExample) |
| MX (1) | MX371344B (enExample) |
| NZ (3) | NZ744109A (enExample) |
| PL (3) | PL3470432T3 (enExample) |
| PT (2) | PT3470432T (enExample) |
| RS (1) | RS58091B1 (enExample) |
| RU (1) | RU2690675C2 (enExample) |
| SG (2) | SG11201500889TA (enExample) |
| SI (1) | SI2888281T1 (enExample) |
| TW (1) | TWI656880B (enExample) |
| UY (1) | UY34984A (enExample) |
| WO (1) | WO2014031610A1 (enExample) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7608693B2 (en) * | 2006-10-02 | 2009-10-27 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human IL-4 receptor |
| EP3354280B1 (en) | 2010-10-06 | 2020-07-29 | Regeneron Pharmaceuticals, Inc. | Stabilized formulations containing anti-interleukin-4 receptor (il-4r) antibodies |
| WO2014031610A1 (en) | 2012-08-21 | 2014-02-27 | Sanofi | Methods for treating or preventing asthma by administering an il-4r antagonist |
| TWI739625B (zh) * | 2012-08-21 | 2021-09-11 | 法商賽諾菲生物技術公司 | 投與il-4r拮抗劑以治療或預防氣喘之方法 |
| ES2981062T3 (es) | 2012-09-07 | 2024-10-07 | Regeneron Pharma | Métodos para el tratamiento de la dermatitis atópica administrando un antagonista de IL-4R |
| TWI633891B (zh) | 2013-06-04 | 2018-09-01 | 再生元醫藥公司 | 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法 |
| SI3010539T1 (sl) | 2013-06-21 | 2019-11-29 | Regeneron Pharma | Postopki za zdravljenje nazalne polipoze z administriranjem antagonista IL-4R |
| TWI634900B (zh) | 2013-07-11 | 2018-09-11 | 再生元醫藥公司 | 藉由投與il-4r抑制劑治療嗜酸性食道炎的方法 |
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