JP2015523577A5 - - Google Patents
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- JP2015523577A5 JP2015523577A5 JP2015524456A JP2015524456A JP2015523577A5 JP 2015523577 A5 JP2015523577 A5 JP 2015523577A5 JP 2015524456 A JP2015524456 A JP 2015524456A JP 2015524456 A JP2015524456 A JP 2015524456A JP 2015523577 A5 JP2015523577 A5 JP 2015523577A5
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- 238000004458 analytical method Methods 0.000 claims description 31
- 238000005286 illumination Methods 0.000 claims description 31
- 239000012780 transparent material Substances 0.000 claims description 16
- 239000000463 material Substances 0.000 claims description 12
- 230000003287 optical effect Effects 0.000 claims description 12
- 238000003384 imaging method Methods 0.000 claims description 10
- 239000012530 fluid Substances 0.000 claims description 6
- 230000003068 static effect Effects 0.000 claims description 4
- 210000004027 cell Anatomy 0.000 description 25
- 238000000034 method Methods 0.000 description 11
- 239000002245 particle Substances 0.000 description 6
- 239000000203 mixture Substances 0.000 description 5
- 239000002771 cell marker Substances 0.000 description 3
- 239000003550 marker Substances 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 101710160107 Outer membrane protein A Proteins 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 150000007523 nucleic acids Chemical class 0.000 description 2
- 102000039446 nucleic acids Human genes 0.000 description 2
- 108020004707 nucleic acids Proteins 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000004075 alteration Effects 0.000 description 1
- 238000000149 argon plasma sintering Methods 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 238000007431 microscopic evaluation Methods 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261675811P | 2012-07-25 | 2012-07-25 | |
| US61/675,811 | 2012-07-25 | ||
| US201261676178P | 2012-07-26 | 2012-07-26 | |
| US61/676,178 | 2012-07-26 | ||
| US201361766116P | 2013-02-18 | 2013-02-18 | |
| US61/766,116 | 2013-02-18 | ||
| US201361802194P | 2013-03-15 | 2013-03-15 | |
| US61/802,194 | 2013-03-15 | ||
| PCT/US2013/052141 WO2014018805A2 (en) | 2012-07-25 | 2013-07-25 | Image analysis and measurement of biological samples |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017226894A Division JP2018031798A (ja) | 2012-07-25 | 2017-11-27 | 生物学的サンプルの画像分析および測定 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015523577A JP2015523577A (ja) | 2015-08-13 |
| JP2015523577A5 true JP2015523577A5 (enExample) | 2016-08-18 |
| JP6273276B2 JP6273276B2 (ja) | 2018-01-31 |
Family
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Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015524456A Expired - Fee Related JP6273276B2 (ja) | 2012-07-25 | 2013-07-25 | 生物学的サンプルの画像分析および測定 |
| JP2017226894A Withdrawn JP2018031798A (ja) | 2012-07-25 | 2017-11-27 | 生物学的サンプルの画像分析および測定 |
| JP2019178947A Withdrawn JP2020020805A (ja) | 2012-07-25 | 2019-09-30 | 生物学的サンプルの画像分析および測定 |
| JP2021117901A Pending JP2021167840A (ja) | 2012-07-25 | 2021-07-16 | 生物学的サンプルの画像分析および測定 |
| JP2022141494A Pending JP2022188029A (ja) | 2012-07-25 | 2022-09-06 | 生物学的サンプルの画像分析および測定 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017226894A Withdrawn JP2018031798A (ja) | 2012-07-25 | 2017-11-27 | 生物学的サンプルの画像分析および測定 |
| JP2019178947A Withdrawn JP2020020805A (ja) | 2012-07-25 | 2019-09-30 | 生物学的サンプルの画像分析および測定 |
| JP2021117901A Pending JP2021167840A (ja) | 2012-07-25 | 2021-07-16 | 生物学的サンプルの画像分析および測定 |
| JP2022141494A Pending JP2022188029A (ja) | 2012-07-25 | 2022-09-06 | 生物学的サンプルの画像分析および測定 |
Country Status (14)
| Country | Link |
|---|---|
| US (8) | US9395302B2 (enExample) |
| EP (2) | EP2877834B1 (enExample) |
| JP (5) | JP6273276B2 (enExample) |
| KR (1) | KR102090776B1 (enExample) |
| CN (2) | CN112557301A (enExample) |
| AU (2) | AU2013295679A1 (enExample) |
| BR (1) | BR112015001592B1 (enExample) |
| CA (2) | CA2878957A1 (enExample) |
| ES (1) | ES2700498T3 (enExample) |
| IL (1) | IL236819A0 (enExample) |
| MX (2) | MX345757B (enExample) |
| SG (1) | SG11201500347SA (enExample) |
| TW (2) | TW201831881A (enExample) |
| WO (1) | WO2014018805A2 (enExample) |
Families Citing this family (118)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9619627B2 (en) | 2011-09-25 | 2017-04-11 | Theranos, Inc. | Systems and methods for collecting and transmitting assay results |
| GB201210403D0 (en) * | 2012-06-13 | 2012-07-25 | Ffei Ltd | Mircoscope colour chart |
| US9513224B2 (en) | 2013-02-18 | 2016-12-06 | Theranos, Inc. | Image analysis and measurement of biological samples |
| ES2700498T3 (es) | 2012-07-25 | 2019-02-18 | Theranos Ip Co Llc | Sistema para el análisis de una muestra |
| AU2014217946A1 (en) * | 2013-02-18 | 2015-08-20 | Theranos Ip Company, Llc | Image analysis and measurement of biological samples |
| US9562860B1 (en) | 2013-06-19 | 2017-02-07 | Theranos, Inc. | Methods and devices for sample analysis |
| DE102013216124A1 (de) * | 2013-08-14 | 2015-02-19 | Carl Zeiss Microscopy Gmbh | Hochauflösende 3D-Fluoreszenzmikroskopie |
| AU2014317986A1 (en) | 2013-09-06 | 2016-03-03 | Theranos Ip Company, Llc | Devices, systems, methods and kits for receiving a swab |
| US9352315B2 (en) | 2013-09-27 | 2016-05-31 | Taiwan Semiconductor Manufacturing Company, Ltd. | Method to produce chemical pattern in micro-fluidic structure |
| US9784670B1 (en) | 2014-01-22 | 2017-10-10 | Theranos, Inc. | Unified detection system for fluorometry, luminometry and spectrometry |
| CN105980854A (zh) | 2014-02-06 | 2016-09-28 | 思甘诺基公司 | 用于检测靶标分析物的检测单元和方法 |
| CN105531529A (zh) * | 2014-04-04 | 2016-04-27 | 生物辐射实验室股份有限公司 | 环状照明结构 |
| US10661268B2 (en) * | 2014-06-30 | 2020-05-26 | Beacon Technologies, LLC | Pipette tip system, device and method of use |
| US9574989B2 (en) * | 2014-08-08 | 2017-02-21 | Omnivision Technologies, Inc. | Lens-free imaging system and method for detecting particles in sample deposited on image sensor |
| GB201506992D0 (en) * | 2014-11-14 | 2015-06-10 | Nplex Pty Ltd | A portable in-vitro diagnostic detector |
| EP4129061A3 (en) | 2014-11-24 | 2023-04-19 | Massachusetts Institute of Technology | Systems, apparatus and methods for analyzing blood cell dynamics |
| TWI566742B (zh) * | 2015-02-26 | 2017-01-21 | 華邦電子股份有限公司 | 分析處理裝置 |
| WO2016191004A1 (en) * | 2015-05-26 | 2016-12-01 | Becton, Dickinson And Company | Methods and systems for high resolution fluorescence microscopy of polymeric dye-labeled samples using polarized light |
| CN108139318A (zh) * | 2015-09-13 | 2018-06-08 | 澳大利亚传感和识别系统私人有限公司 | 分析仪器、相关系统以及方法 |
| WO2017074815A1 (en) | 2015-10-26 | 2017-05-04 | Idexx Laboratories, Inc. | Hematology test slide |
| CN105284240B (zh) * | 2015-10-30 | 2017-10-03 | 山东省农作物种质资源中心 | 种子籽粒颜色分辨台及分辨方法 |
| EP3390963B1 (en) * | 2015-12-18 | 2021-02-17 | Abbott Laboratories | Method for determining the identity of histological stains |
| WO2017117553A1 (en) * | 2015-12-31 | 2017-07-06 | Mec Dynamics | Micro mechanical methods and systems for performing assays |
| TWI568464B (zh) * | 2016-02-05 | 2017-02-01 | Guo-Zhi Liao | Drug release and detection device, method of operation of drug release and detection device, and method for detecting fluorescent substance |
| US11054365B2 (en) * | 2016-02-23 | 2021-07-06 | Shimadzu Corporation | Microscopic analysis device |
| JP7008029B2 (ja) * | 2016-03-01 | 2022-01-25 | モレキュラー デバイシーズ, エルエルシー | 源自己蛍光を低減させ、均一性を改良するための散乱を伴う撮像システムおよび方法 |
| JP6913323B2 (ja) * | 2016-03-11 | 2021-08-04 | 株式会社ニコン | 評価装置、観察装置、及びプログラム |
| JPWO2017159011A1 (ja) * | 2016-03-15 | 2019-01-24 | ソニー株式会社 | 情報処理装置、情報処理方法、プログラム及び情報処理システム |
| WO2017220249A1 (en) * | 2016-06-20 | 2017-12-28 | Plair Sa | Device and method for detecting and/or characterizing fluid-borne particles |
| US10768406B2 (en) | 2016-06-20 | 2020-09-08 | Scanogen Inc. | Imaging system |
| US20190323939A1 (en) * | 2016-06-22 | 2019-10-24 | Kyocera Corporation | Fine particle counter |
| WO2018009384A1 (en) * | 2016-07-06 | 2018-01-11 | Advanced Instruments, Llc | Cuvette and rotor system for blood plasma separation |
| US10768105B1 (en) * | 2016-07-29 | 2020-09-08 | Labrador Diagnostics Llc | Image analysis and measurement of biological samples |
| TWI595372B (zh) * | 2016-08-31 | 2017-08-11 | 義守大學 | 用以檢測蛋白特徵物之顯微影像檢測系統以及顯微影像檢測方法 |
| JP6514832B2 (ja) * | 2016-09-29 | 2019-05-15 | オリンパス株式会社 | 観察装置 |
| WO2018062215A1 (ja) | 2016-09-30 | 2018-04-05 | オリンパス株式会社 | 観察装置 |
| CN108226043B (zh) * | 2016-12-22 | 2024-07-02 | 赛默飞世尔(上海)仪器有限公司 | 用于水质监测的测量单元及测量系统 |
| CN106706643B (zh) * | 2017-02-23 | 2019-07-02 | 马青山 | 一种肝癌对比切片检测方法 |
| JP6938986B2 (ja) * | 2017-03-15 | 2021-09-22 | 住友金属鉱山株式会社 | 粒子形状の評価方法 |
| WO2018195513A1 (en) * | 2017-04-20 | 2018-10-25 | Biomerieux, Inc. | Optical test platform |
| JP6911112B2 (ja) | 2017-05-29 | 2021-07-28 | オリンパス株式会社 | 観察装置 |
| EP4292520A3 (en) | 2017-10-16 | 2024-07-10 | Massachusetts Institute of Technology | Systems, devices and methods for non-invasive hematological measurements |
| CN109697450B (zh) * | 2017-10-20 | 2023-04-07 | 曦医生技股份有限公司 | 细胞分类方法 |
| EP3700419A4 (en) * | 2017-10-26 | 2021-11-10 | Essenlix Corporation | RAPID TEST OF BLOOD PLATES |
| CN107976439B (zh) * | 2017-12-06 | 2019-02-05 | 张哲� | 一种检测血液和尿液样品的光学检测装置 |
| JP6687656B2 (ja) | 2018-03-19 | 2020-04-28 | ファナック株式会社 | 検査装置およびその検査方法 |
| WO2019209345A1 (en) * | 2018-04-27 | 2019-10-31 | Hewlett-Packard Development Company, L.P. | Three-dimensional volume imaging |
| US11371986B2 (en) | 2018-05-25 | 2022-06-28 | Scanogen Inc. | Detection units and methods for detecting a target analyte |
| NL2021377B1 (en) | 2018-07-03 | 2020-01-08 | Illumina Inc | Interposer with first and second adhesive layers |
| US20200033260A1 (en) * | 2018-07-25 | 2020-01-30 | Pauleologos Cusulos | Coagulation and aggregation refracted light indexing device and method |
| BR112021001864B1 (pt) * | 2018-08-01 | 2022-08-23 | Cdx Medical Ip, Inc | Sistema para geração de uma imagem digital composta de uma amostra biológica |
| SE542345C2 (en) * | 2018-08-03 | 2020-04-14 | Redsense Medical Ab | Device for measuring a property of a measurement object by luminescence |
| EP3611695A1 (en) * | 2018-08-15 | 2020-02-19 | Koninklijke Philips N.V. | Generating annotation data of tissue images |
| WO2020037176A1 (en) | 2018-08-17 | 2020-02-20 | Enrich Therapeutics Inc. | A system and method to select and isolate particles and cells and uses thereof |
| CN109084734B (zh) * | 2018-08-17 | 2020-06-16 | 中国科学院自动化研究所 | 基于单目显微视觉的微球姿态测量装置及测量方法 |
| CN109100352B (zh) * | 2018-08-30 | 2024-07-23 | 天津港东科技股份有限公司 | 显微镜多功能液体测试装置 |
| JP2022001889A (ja) * | 2018-09-27 | 2022-01-06 | 富士フイルム株式会社 | フォーカス位置評価装置、方法及びプログラム、並びに判別器 |
| CN109583470A (zh) * | 2018-10-17 | 2019-04-05 | 阿里巴巴集团控股有限公司 | 一种异常检测的解释特征确定方法和装置 |
| AU2019370154B2 (en) | 2018-11-02 | 2025-02-27 | Hologic, Inc. | Digital imaging system and method |
| US11232561B2 (en) | 2019-01-22 | 2022-01-25 | Applied Materials, Inc. | Capture and storage of magnified images |
| US10724956B1 (en) * | 2019-02-01 | 2020-07-28 | Essen Instruments, Inc. | Spectral unmixing |
| KR102114135B1 (ko) * | 2019-02-28 | 2020-05-22 | 서강대학교산학협력단 | 현미경 장치 및 현미경 장치의 동작방법 |
| CN110057730A (zh) * | 2019-03-12 | 2019-07-26 | 天津大学 | 一种人体颗粒物主动吸入浓度测试方法 |
| US11255785B2 (en) | 2019-03-14 | 2022-02-22 | Applied Materials, Inc. | Identifying fiducial markers in fluorescence microscope images |
| US11469075B2 (en) | 2019-03-14 | 2022-10-11 | Applied Materials, Inc. | Identifying fiducial markers in microscope images |
| CN120801199A (zh) | 2019-04-05 | 2025-10-17 | 上海宜晟生物科技有限公司 | 测定准确度以及可靠性提高 |
| EP3997434A4 (en) * | 2019-07-09 | 2023-07-26 | The Regents of the University of California | Automated rapid on-site evaluation machine and stain |
| AU2020309098A1 (en) * | 2019-07-11 | 2022-03-10 | Sensibility Pty Ltd | Machine learning based phone imaging system and analysis method |
| WO2021015843A1 (en) | 2019-07-24 | 2021-01-28 | Massachusetts Institute Of Technology | Finger inserts for a nailfold imaging device |
| CN114175178A (zh) * | 2019-07-31 | 2022-03-11 | 迪格实验室公司 | 动物健康评估 |
| US11763920B2 (en) | 2019-07-31 | 2023-09-19 | Dig Labs Corporation | Mucus analysis for animal health assessments |
| CN110490882B (zh) * | 2019-08-19 | 2022-12-27 | 腾讯科技(深圳)有限公司 | 细胞膜染色图像分析方法、装置及系统 |
| CA3150506A1 (en) * | 2019-09-22 | 2021-03-25 | Erick GARCIA CORDERO | DEVICE AND METHOD FOR ASSESSING RISK OF PREMATURE BIRTH |
| CN114556413A (zh) | 2019-09-24 | 2022-05-27 | 应用材料公司 | 用于组织分割的机器学习模型的交互式训练 |
| CN112630197B (zh) * | 2019-10-10 | 2021-10-19 | 东北农业大学 | 一种判定蛋白质能否发生液-液相分离的方法 |
| WO2021077075A1 (en) * | 2019-10-19 | 2021-04-22 | SequLITE Genomics US, Inc. | Virtual fiducials |
| GB2588627B (en) * | 2019-10-29 | 2023-03-29 | Oxford Nanoimaging Ltd | An optical imaging system |
| EP3836020B1 (en) * | 2019-12-12 | 2024-08-28 | National Cheng Kung University | A method for determining cellular nuclear-to-cytoplasmic ratio |
| US20210182531A1 (en) | 2019-12-17 | 2021-06-17 | Applied Materials, Inc. | Registration techniques for multiplexed fluorescence in-situ hybridization images |
| US10823662B1 (en) * | 2020-02-18 | 2020-11-03 | Horiba Instruments, Incorporated | Special purpose cuvette assembly and method for optical microscopy of nanoparticle colloids |
| US12480941B2 (en) * | 2020-03-13 | 2025-11-25 | Advanced Animal Diagnostics, Inc. | Rapid mobile screening and triage for infections and infection severity |
| JP2022523216A (ja) * | 2020-03-27 | 2022-04-21 | 肯維捷斯(武漢)科技有限公司 | 顕微結像暗視野照明装置 |
| EP4134725B1 (en) * | 2020-04-08 | 2025-02-26 | BGI Shenzhen | Lens-free microscopic imaging system and method, and biochemical substance detection system and method |
| GB202006259D0 (en) * | 2020-04-28 | 2020-06-10 | Leeds Teaching Hospitals Nhs Trust | Stain Assessment |
| US11925456B2 (en) | 2020-04-29 | 2024-03-12 | Hyperspectral Corp. | Systems and methods for screening asymptomatic virus emitters |
| CA3185035A1 (en) | 2020-05-28 | 2021-12-02 | Leuko Labs, Inc. | METHOD FOR DETECTING WHITE BLOOD BLOOD BLOOD CELLS AND/OR WHITE BLOOD BLOOD SUBTYPES FROM NON-INVASIVE CAPILLARY VIDEOS |
| US12144619B2 (en) | 2020-07-06 | 2024-11-19 | Look Tec Co., Ltd | Blood measurement device |
| KR102331711B1 (ko) * | 2020-08-21 | 2021-12-01 | 동아대학교 산학협력단 | 현장진료를 위한 미세유체칩 다중 채널 형광측정 장치 |
| US12111257B2 (en) * | 2020-08-26 | 2024-10-08 | Honeywell International Inc. | Fluid composition sensor device and method of using the same |
| JP7568212B2 (ja) * | 2020-08-27 | 2024-10-16 | リプロバイオ株式会社 | 精子運動性能評価システム及び精子運動性能評価方法 |
| EP3961287B1 (de) * | 2020-09-01 | 2025-02-12 | BMG Labtech GmbH | Autofokussystem für eine optische mess- oder mikroskopievorrichtung, verfahren zur fokuseinstellung bei einer optischen mess- oder mikroskopievorrichtung sowie optische mess- oder mikroskopievorrichtung |
| CN116783660A (zh) * | 2020-10-08 | 2023-09-19 | Essenlix 公司 | 减少测定错误 |
| US12209964B2 (en) | 2020-10-15 | 2025-01-28 | Visera Technologies Company Limited | Bio-chip, bio-detection system and bio-detection method |
| TWI767415B (zh) * | 2020-11-18 | 2022-06-11 | 中國醫藥大學 | 自動化血液分析系統及自動化血液分析方法 |
| CN112419295B (zh) * | 2020-12-03 | 2024-08-23 | 腾讯科技(深圳)有限公司 | 医学图像处理方法、装置、计算机设备和存储介质 |
| KR102501486B1 (ko) * | 2020-12-10 | 2023-02-17 | 한국화학연구원 | 나노 입자 또는 나노 구조체에서 발생된 분광 신호 분석 시스템 및 분석 방법 |
| CN214895849U (zh) | 2021-01-28 | 2021-11-26 | 贝克曼库尔特生物科技(苏州)有限公司 | 气泡检测装置和样本处理仪 |
| US20250270662A1 (en) * | 2021-05-20 | 2025-08-28 | Jason P. Gleghorn | Method for enumeration and physical characterization of nanoparticles |
| JP2024530213A (ja) | 2021-08-10 | 2024-08-16 | ルニット・インコーポレイテッド | 病理スライド画像に関する情報を出力する方法及び装置 |
| CN113790671B (zh) * | 2021-09-03 | 2022-05-17 | 苏州天准科技股份有限公司 | 一种口径可调的落射光源及影像测量仪 |
| EP4453628A1 (en) * | 2021-12-23 | 2024-10-30 | Radiometer Medical ApS | Biological fluid analyser with adaptive light source assembly |
| CN118715549A (zh) * | 2021-12-23 | 2024-09-27 | 雷迪奥米特医学公司 | 具有基于光设置的细胞分类的生物流体分析仪 |
| TWI813145B (zh) * | 2022-01-25 | 2023-08-21 | 佛教慈濟醫療財團法人 | 多重螢光組織影像分析方法及其系統 |
| US20250216394A1 (en) * | 2022-01-28 | 2025-07-03 | University Of Southern California | Liquid biopsy analytes to define cancer stages |
| CN116698707A (zh) * | 2022-02-24 | 2023-09-05 | 杭州迅数科技有限公司 | 一种双光路双波长的光染色菌落成像装置 |
| WO2023166655A1 (ja) * | 2022-03-03 | 2023-09-07 | オリンパス株式会社 | 照明ユニットおよび撮影システム |
| BR102023003038A2 (pt) * | 2022-03-17 | 2024-01-02 | Sysmex Corporation | Método para classificar glóbulos brancos em subpopulações |
| CN114895449B (zh) * | 2022-03-17 | 2023-06-23 | 华东师范大学 | 一种基于压缩感知的四维高速荧光显微成像装置 |
| TWI798041B (zh) * | 2022-03-31 | 2023-04-01 | 中原大學 | 用於執行全內反射散射量測的裝置與方法 |
| KR102537348B1 (ko) * | 2022-08-04 | 2023-05-30 | 한국기계연구원 | 디지털 pcr 분석용 기판 및 이의 제작방법 |
| TWI866690B (zh) * | 2023-02-07 | 2024-12-11 | 邦睿生技股份有限公司 | 生物樣品檢測裝置 |
| TWI876356B (zh) * | 2023-05-30 | 2025-03-11 | 天亮醫療器材股份有限公司 | 檢測管、檢測系統及待測體參數的光學檢測方法 |
| TWI860738B (zh) * | 2023-06-05 | 2024-11-01 | 崑山科技大學 | 染色輔助螢光影像偵測現地環境氯苯之方法 |
| CN119394870A (zh) * | 2023-07-21 | 2025-02-07 | 上海浚真生命科学有限公司 | 光学成像传感器和生物反应系统 |
| WO2025128682A1 (en) * | 2023-12-15 | 2025-06-19 | Idexx Laboratories, Inc. | Process and systems for autofocusing and measuring tilt of sample plane |
| WO2025137530A1 (en) * | 2023-12-22 | 2025-06-26 | Idexx Laboratories, Inc. | Systems and methods for uniform oblique illumination for optical imaging |
| WO2025145095A1 (en) * | 2023-12-29 | 2025-07-03 | Beckman Coulter, Inc. | Customized sample handling in biological analysis |
| KR102832369B1 (ko) * | 2025-05-19 | 2025-07-14 | (주)디로펫 | 정량적 위상 이미징 장치와 이를 이용한 비브리오패혈증 모니터링 방법 |
Family Cites Families (122)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4066362A (en) * | 1968-08-16 | 1978-01-03 | E. I. Du Pont De Nemours And Company | Apparatus and method for performing photometric analysis |
| GB1382081A (en) | 1972-03-14 | 1975-01-29 | Ici Ltd | Transmission spectra |
| US3849654A (en) | 1973-10-19 | 1974-11-19 | H Malvin | Fluorescence cuvette |
| US4305816A (en) * | 1980-02-11 | 1981-12-15 | Borden, Inc. | Apparatus and method for inspecting containers |
| US5109429A (en) * | 1985-11-04 | 1992-04-28 | Cell Analysis Systems,Inc. | Apparatus and method for analyses of biological specimens |
| US4868126A (en) | 1985-12-11 | 1989-09-19 | Flow Cytometry Standards Corporation | Method of calibrating a fluorescent microscope using fluorescent calibration microbeads simulating stained cells |
| US4896966A (en) | 1986-08-15 | 1990-01-30 | Hamilton-Thorn Research | Motility scanner and method |
| US5289255A (en) * | 1991-03-28 | 1994-02-22 | Minnesota Mining And Manufacturing Co. | Cuvette for use in making a measurement of a blood parameter and assembly utilizing the same |
| JPH05240774A (ja) * | 1992-03-02 | 1993-09-17 | Hitachi Ltd | 光学セル及び光学検出装置とこれを用いる試料分離検出装置 |
| US5292484A (en) * | 1992-07-16 | 1994-03-08 | Spectrum Systems, Inc. | Cuvette and cuvette cartridge for a chemical analyzer |
| US5585246A (en) * | 1993-02-17 | 1996-12-17 | Biometric Imaging, Inc. | Method for preparing a sample in a scan capillary for immunofluorescent interrogation |
| ES2150985T3 (es) | 1993-02-26 | 2000-12-16 | E Y Lab Inc | Procedimiento y sistema de analisis optico de muestras. |
| US5374531A (en) * | 1993-03-22 | 1994-12-20 | Zynaxis, Inc. | Immunoassay for determination of cells |
| US5534416A (en) * | 1993-04-13 | 1996-07-09 | Molecular Probes, Inc. | Fluorescent viability assay using cyclic-substituted unsymmetrical cyanine dyes |
| US5407638A (en) | 1993-04-28 | 1995-04-18 | Shell Oil Company | Detector-cell adapted for continuous-flow absorption detection |
| DE69404652T2 (de) | 1993-05-28 | 1998-01-15 | Fisons Plc | Analysegerät |
| US5510621A (en) * | 1994-10-03 | 1996-04-23 | Optical Solutions, Inc. | Apparatus and method for measuring components in a bag |
| US5869689A (en) * | 1995-10-17 | 1999-02-09 | Molecular Probes, Inc | Stains for acidic organelles |
| AU2139597A (en) * | 1996-05-13 | 1997-12-05 | Dhc Analysis, Inc. | Sampling device for spectrometric measurements |
| JP3322579B2 (ja) | 1996-10-17 | 2002-09-09 | 株式会社エンプラス | サイドライト型面光源装置 |
| US7117098B1 (en) | 1997-02-27 | 2006-10-03 | Cellomics, Inc. | Machine-readable storage medium for analyzing distribution of macromolecules between the cell membrane and the cell cytoplasm |
| EP0985142A4 (en) * | 1997-05-23 | 2006-09-13 | Lynx Therapeutics Inc | SYSTEM AND APPARATUS FOR THE SEQUENTIAL TREATMENT OF ANALYTES |
| GB2326229A (en) * | 1997-06-13 | 1998-12-16 | Robert Jeffrey Geddes Carr | Detecting and analysing submicron particles |
| DE19735119C2 (de) | 1997-08-13 | 2000-05-18 | Deutsches Krebsforsch | Verfahren zur Fluoreszenzkorrelationsspektroskopie, insbesbesondere zur Mehrfarben-Fluoreszenzkorrelationsspektroskopie und Vorrichtung zur Durchführung des Verfahrens |
| US20030205681A1 (en) | 1998-07-22 | 2003-11-06 | Ljl Biosystems, Inc. | Evanescent field illumination devices and methods |
| DE19801139B4 (de) | 1998-01-14 | 2016-05-12 | Till Photonics Gmbh | Punktabtastendes Luminiszenz-Mikroskop |
| US6529835B1 (en) * | 1998-06-25 | 2003-03-04 | Caliper Technologies Corp. | High throughput methods, systems and apparatus for performing cell based screening assays |
| SE9802558D0 (sv) | 1998-07-16 | 1998-07-16 | Hanning Instr Ab | Device for detection of fluorescent |
| WO2000017624A2 (en) * | 1998-09-22 | 2000-03-30 | Cellomics, Inc. | Miniaturized cell array methods and apparatus for cell-based screening |
| US7450229B2 (en) | 1999-01-25 | 2008-11-11 | Amnis Corporation | Methods for analyzing inter-cellular phenomena |
| US20020019062A1 (en) | 1999-06-18 | 2002-02-14 | Peter Lea | Assay devices |
| JP3820806B2 (ja) | 1999-07-21 | 2006-09-13 | 三菱電機株式会社 | レーザ検査装置 |
| AU6754900A (en) | 1999-08-03 | 2001-02-19 | Biophysica, Llc | Spectroscopic systems and methods for detecting tissue properties |
| IL131282A (en) | 1999-08-05 | 2009-02-11 | Orbotech Ltd | Apparatus and methods for inspection of objects |
| DE10017823B4 (de) | 2000-04-10 | 2004-08-26 | Till I.D. Gmbh | Mikroskopische Beleuchtungsvorrichtung |
| US20020192763A1 (en) * | 2000-04-17 | 2002-12-19 | Jiangchun Xu | Compositions and methods for the therapy and diagnosis of prostate cancer |
| DE10029946A1 (de) | 2000-06-17 | 2001-12-20 | Merck Patent Gmbh | Integrierte optische Wellenleiter für mikrofluidische Analysensysteme |
| US6599475B1 (en) | 2000-09-27 | 2003-07-29 | Becton, Dickinson And Company | Apparatus for producing thin liquid samples for microscopic analysis |
| DE10124055A1 (de) | 2001-05-16 | 2002-11-21 | Fisher Rosemount Mfg Gmbh & Co | Gerät zur optischen Untersuchung von Gasen |
| AU2002363076A1 (en) * | 2001-10-26 | 2003-05-06 | Virtual Arrays, Inc. | Assay systems with adjustable fluid communication |
| JP2003139687A (ja) * | 2001-11-06 | 2003-05-14 | Fuji Photo Film Co Ltd | 測定チップ集合体および測定チップ取出し装置 |
| JP3801914B2 (ja) * | 2001-12-25 | 2006-07-26 | 富士写真フイルム株式会社 | 測定チップの再使用方法 |
| US7756305B2 (en) * | 2002-01-23 | 2010-07-13 | The Regents Of The University Of California | Fast 3D cytometry for information in tissue engineering |
| US20050153435A1 (en) | 2002-02-14 | 2005-07-14 | Solus Biosystems, Inc. | Multiple sample screening using a silicon substrate |
| ATE336718T1 (de) * | 2002-04-03 | 2006-09-15 | Univ Jw Goethe Frankfurt Main | Infrarotmessvorrichtung für die spektrometrie wässriger und nicht wässriger systeme |
| US6723288B2 (en) | 2002-04-29 | 2004-04-20 | Dade Behring Inc. | Method of providing assay processing in a multi-analyzer system |
| US7354389B2 (en) * | 2002-05-28 | 2008-04-08 | Autogenomics, Inc. | Microarray detector and methods |
| GB0216934D0 (en) * | 2002-07-20 | 2002-08-28 | Council Cent Lab Res Councils | Optical apparatus |
| US7122384B2 (en) | 2002-11-06 | 2006-10-17 | E. I. Du Pont De Nemours And Company | Resonant light scattering microparticle methods |
| EP1565726A2 (en) * | 2002-11-22 | 2005-08-24 | Solus Biosystems, Inc. | High throughput screening with parallel vibrational spectroscopy |
| US20110259744A1 (en) * | 2003-04-30 | 2011-10-27 | Moyle William R | Sensors for biomolecular detection and cell classification |
| JP4838135B2 (ja) * | 2003-05-20 | 2011-12-14 | フルイディグム コーポレイション | マイクロ流体素子およびこれを撮像するための方法および装置 |
| CN1813183A (zh) * | 2003-06-25 | 2006-08-02 | 皇家飞利浦电子股份有限公司 | 用于灵敏检测渐逝场的具表面构造的载体 |
| EP1494007B8 (de) * | 2003-06-30 | 2014-09-24 | Tecan Trading AG | Vorrichtung und Verfahren zum Analysieren von Proben |
| AU2003904237A0 (en) * | 2003-08-08 | 2003-08-21 | Garvan Institute Of Medical Research | Novel translocation assay |
| JP3879001B2 (ja) | 2003-11-06 | 2007-02-07 | 独立行政法人情報通信研究機構 | 生物試料を高精度に測定する方法 |
| US7804075B2 (en) * | 2004-03-11 | 2010-09-28 | The General Hospital Corporation | Method and system for tomographic imaging using fluorescent proteins |
| US8103080B2 (en) * | 2004-03-16 | 2012-01-24 | Amnis Corporation | Method for imaging and differential analysis of cells |
| JP2005316383A (ja) * | 2004-03-29 | 2005-11-10 | Nikon Corp | 蛍光顕微鏡 |
| DE602005023141D1 (de) | 2004-04-16 | 2010-10-07 | Univ Auburn | Mikroskopbeleuchtungsvorrichtung und adapter dafür |
| JP4911722B2 (ja) | 2004-06-07 | 2012-04-04 | フルイディグム コーポレイション | 微小流体素子のための光学レンズシステムおよび方法 |
| US8313713B2 (en) * | 2004-06-17 | 2012-11-20 | Ortho-Clinical Diagnostics, Inc. | Stabilizing a cuvette during measurement |
| JP4363649B2 (ja) | 2004-09-30 | 2009-11-11 | 富士フイルム株式会社 | 全反射減衰を利用した測定装置及び方法 |
| JP2006162427A (ja) * | 2004-12-07 | 2006-06-22 | Toshiba Corp | Ledチップの検査方法及びledチップの検査装置 |
| WO2006062987A2 (en) | 2004-12-09 | 2006-06-15 | Inneroptic Technology, Inc. | Apparatus, system and method for optically analyzing substrate |
| US20060166305A1 (en) | 2005-01-27 | 2006-07-27 | Genetix Limited | Animal cell confluence detection method and apparatus |
| WO2006084283A2 (en) * | 2005-01-31 | 2006-08-10 | The Board Of Trustees Of The University Of Illinois | Methods and devices for characterizing particles in clear and turbid media |
| US7344273B2 (en) * | 2005-03-22 | 2008-03-18 | Binary Works, Inc. | Ring light with user manipulable control |
| ES2820430T3 (es) | 2005-05-09 | 2021-04-21 | Labrador Diagnostics Llc | Sistemas de fluidos para centros de atención y usos de los mismos |
| US7817273B2 (en) * | 2005-06-30 | 2010-10-19 | Life Technologies Corporation | Two-dimensional spectral imaging system |
| JP2007127449A (ja) | 2005-11-01 | 2007-05-24 | Olympus Corp | 測定容器 |
| DE102005062439B3 (de) | 2005-12-23 | 2007-05-10 | JOMESA Meßsysteme GmbH | Verfahren für die Partikelanalyse und Partikelanalysesystem |
| US8101368B2 (en) * | 2006-02-13 | 2012-01-24 | Dvs Sciences Inc. | Quantitation of cellular DNA and cell numbers using element labeling |
| JP2007271360A (ja) * | 2006-03-30 | 2007-10-18 | Fujifilm Corp | 測定装置及びセンサユニットの保持方法 |
| US8007999B2 (en) | 2006-05-10 | 2011-08-30 | Theranos, Inc. | Real-time detection of influenza virus |
| JP2007333497A (ja) * | 2006-06-14 | 2007-12-27 | Hitachi High-Technologies Corp | 蛍光検出デバイスおよび装置 |
| US8501099B2 (en) | 2006-07-11 | 2013-08-06 | The Curators Of The University Of Missouri | Photo-acoustic detection device and method |
| CN101622522A (zh) * | 2007-01-26 | 2010-01-06 | 贝克顿·迪金森公司 | 用于细胞计数和分析的方法、系统和组合物 |
| US7936463B2 (en) | 2007-02-05 | 2011-05-03 | Palo Alto Research Center Incorporated | Containing analyte in optical cavity structures |
| JP5286774B2 (ja) * | 2007-04-11 | 2013-09-11 | 株式会社ニコン | 顕微鏡装置と、これに用いられる蛍光キューブ |
| US7808641B2 (en) * | 2007-04-13 | 2010-10-05 | C Technologies Inc. | Interactive variable pathlength device |
| EP2012110A1 (en) | 2007-07-06 | 2009-01-07 | Bp Oil International Limited | Optical cell |
| US8158430B1 (en) | 2007-08-06 | 2012-04-17 | Theranos, Inc. | Systems and methods of fluidic sample processing |
| US7952705B2 (en) * | 2007-08-24 | 2011-05-31 | Dynamic Throughput Inc. | Integrated microfluidic optical device for sub-micro liter liquid sample microspectroscopy |
| JP5057377B2 (ja) * | 2007-08-30 | 2012-10-24 | 国立大学法人埼玉大学 | 生体成分又はその機能の測定方法及び装置 |
| CN104297507B (zh) | 2007-10-02 | 2017-10-10 | 赛拉诺斯股份有限公司 | 模块化现场护理装置及其应用 |
| EP2208053A2 (en) * | 2007-11-05 | 2010-07-21 | Koninklijke Philips Electronics N.V. | Microelectronic optical evanescent field sensor |
| CN201156031Y (zh) | 2008-02-02 | 2008-11-26 | 施慧勇 | 生化分析仪比色杯 |
| CN102084241B (zh) * | 2008-03-21 | 2015-02-18 | 艾博特健康公司 | 使用荧光淬灭和/或漂白分析个体细胞或微粒的方法及设备 |
| WO2009117682A1 (en) * | 2008-03-21 | 2009-09-24 | Abbott Point Of Care, Inc. | Method and apparatus for detecting and counting platelets individually and in aggregate clumps |
| WO2009142312A1 (ja) * | 2008-05-20 | 2009-11-26 | 株式会社ニコン | 顕微鏡装置 |
| JP2010060854A (ja) * | 2008-09-04 | 2010-03-18 | Nikon Corp | 顕微鏡装置 |
| JP2010091679A (ja) * | 2008-10-06 | 2010-04-22 | Nikon Corp | 顕微鏡装置とこれに用いられる蛍光キューブ |
| JP2010091809A (ja) * | 2008-10-08 | 2010-04-22 | Nikon Corp | 顕微鏡装置 |
| EP2361375B1 (de) | 2008-11-19 | 2018-10-10 | Postnova Analytics GmbH | Zellaufbau für lichtstreudetektoren mit selbstfokussierenden eigenschaften |
| US8329117B2 (en) | 2009-05-14 | 2012-12-11 | Canon U.S. Life Sciences, Inc. | Microfluidic chip features for optical and thermal isolation |
| US8891086B2 (en) * | 2009-06-15 | 2014-11-18 | Thermo Scientific Portable Analytical Instruments Inc. | Optical scanning systems and methods for measuring a sealed container with a layer for reducing diffusive scattering |
| JP2011118264A (ja) * | 2009-12-07 | 2011-06-16 | Nikon Corp | 顕微鏡装置 |
| WO2011072401A1 (en) | 2009-12-18 | 2011-06-23 | University Health Network | System and method for sub-surface fluorescence imaging |
| EP2339327A1 (en) * | 2009-12-23 | 2011-06-29 | F. Hoffmann-La Roche AG | Automatic test for imaging units |
| JP5344629B2 (ja) * | 2010-04-30 | 2013-11-20 | レーザーテック株式会社 | 検査装置及び検査方法 |
| EP2586041A1 (en) * | 2010-06-22 | 2013-05-01 | Koninklijke Philips Electronics N.V. | Detection of magnetic particles and their clustering |
| JP5703609B2 (ja) | 2010-07-02 | 2015-04-22 | ソニー株式会社 | 顕微鏡及び領域判定方法 |
| TW201224425A (en) * | 2010-12-03 | 2012-06-16 | Microtek Int Inc | Carrying device and method of containing specimen within the carrying device |
| KR20120080056A (ko) * | 2011-01-06 | 2012-07-16 | 삼성전자주식회사 | 디스크 및 이를 이용한 검사장치의 보정방법 |
| EP2666008B1 (en) | 2011-01-21 | 2021-08-11 | Labrador Diagnostics LLC | Systems and methods for sample use maximization |
| CA2828487C (en) | 2011-03-07 | 2022-11-08 | James Stewart Aitchison | Method and system for portable cell detection and analysis using microfluidic technology |
| KR101167649B1 (ko) * | 2011-04-20 | 2012-07-20 | 한국과학기술원 | 세포 환경 내에서의 단일 분자 수준의 단백질-단백질 상호작용 분석 장치 |
| US8934698B2 (en) | 2011-06-22 | 2015-01-13 | The Johns Hopkins University | System and device for characterizing cells |
| US8380541B1 (en) | 2011-09-25 | 2013-02-19 | Theranos, Inc. | Systems and methods for collecting and transmitting assay results |
| CN202514348U (zh) | 2011-12-23 | 2012-11-07 | 鹤山健豪灯饰企业有限公司 | 具观赏生命成长过程的组合式小夜灯 |
| US9513224B2 (en) | 2013-02-18 | 2016-12-06 | Theranos, Inc. | Image analysis and measurement of biological samples |
| US20140193892A1 (en) | 2012-07-25 | 2014-07-10 | Theranos, Inc. | Image analysis and measurement of biological samples |
| ES2700498T3 (es) | 2012-07-25 | 2019-02-18 | Theranos Ip Co Llc | Sistema para el análisis de una muestra |
| AU2014217946A1 (en) | 2013-02-18 | 2015-08-20 | Theranos Ip Company, Llc | Image analysis and measurement of biological samples |
| US20150071541A1 (en) | 2013-08-14 | 2015-03-12 | Rice University | Automated method for measuring, classifying, and matching the dynamics and information passing of single objects within one or more images |
| CA2921372A1 (en) | 2013-08-22 | 2015-02-26 | California Institute Of Technology | Variable-illumination fourier ptychographic imaging devices, systems, and methods |
| TWI496112B (zh) | 2013-09-13 | 2015-08-11 | Univ Nat Cheng Kung | 細胞影像分割方法以及核質比評估方法 |
| EP3396428A4 (en) | 2015-12-22 | 2019-08-28 | Olympus Corporation | MICROSCOPE SYSTEM |
| US9930243B2 (en) | 2016-05-02 | 2018-03-27 | Mitutoyo Corporation | Variable focal length imaging system |
| US10768406B2 (en) | 2016-06-20 | 2020-09-08 | Scanogen Inc. | Imaging system |
| US10768105B1 (en) * | 2016-07-29 | 2020-09-08 | Labrador Diagnostics Llc | Image analysis and measurement of biological samples |
-
2013
- 2013-07-25 ES ES13747735T patent/ES2700498T3/es active Active
- 2013-07-25 CA CA2878957A patent/CA2878957A1/en active Pending
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