JP2015523577A5 - - Google Patents

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JP2015523577A5
JP2015523577A5 JP2015524456A JP2015524456A JP2015523577A5 JP 2015523577 A5 JP2015523577 A5 JP 2015523577A5 JP 2015524456 A JP2015524456 A JP 2015524456A JP 2015524456 A JP2015524456 A JP 2015524456A JP 2015523577 A5 JP2015523577 A5 JP 2015523577A5
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JP6273276B2 (ja
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JP2015524456A 2012-07-25 2013-07-25 生物学的サンプルの画像分析および測定 Expired - Fee Related JP6273276B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201261675811P 2012-07-25 2012-07-25
US61/675,811 2012-07-25
US201261676178P 2012-07-26 2012-07-26
US61/676,178 2012-07-26
US201361766116P 2013-02-18 2013-02-18
US61/766,116 2013-02-18
US201361802194P 2013-03-15 2013-03-15
US61/802,194 2013-03-15
PCT/US2013/052141 WO2014018805A2 (en) 2012-07-25 2013-07-25 Image analysis and measurement of biological samples

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JP2017226894A Division JP2018031798A (ja) 2012-07-25 2017-11-27 生物学的サンプルの画像分析および測定

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JP2015523577A JP2015523577A (ja) 2015-08-13
JP2015523577A5 true JP2015523577A5 (OSRAM) 2016-08-18
JP6273276B2 JP6273276B2 (ja) 2018-01-31

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JP2015524456A Expired - Fee Related JP6273276B2 (ja) 2012-07-25 2013-07-25 生物学的サンプルの画像分析および測定
JP2017226894A Withdrawn JP2018031798A (ja) 2012-07-25 2017-11-27 生物学的サンプルの画像分析および測定
JP2019178947A Withdrawn JP2020020805A (ja) 2012-07-25 2019-09-30 生物学的サンプルの画像分析および測定
JP2021117901A Pending JP2021167840A (ja) 2012-07-25 2021-07-16 生物学的サンプルの画像分析および測定
JP2022141494A Pending JP2022188029A (ja) 2012-07-25 2022-09-06 生物学的サンプルの画像分析および測定

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JP2017226894A Withdrawn JP2018031798A (ja) 2012-07-25 2017-11-27 生物学的サンプルの画像分析および測定
JP2019178947A Withdrawn JP2020020805A (ja) 2012-07-25 2019-09-30 生物学的サンプルの画像分析および測定
JP2021117901A Pending JP2021167840A (ja) 2012-07-25 2021-07-16 生物学的サンプルの画像分析および測定
JP2022141494A Pending JP2022188029A (ja) 2012-07-25 2022-09-06 生物学的サンプルの画像分析および測定

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US (8) US9395302B2 (OSRAM)
EP (2) EP3495799B1 (OSRAM)
JP (5) JP6273276B2 (OSRAM)
KR (1) KR102090776B1 (OSRAM)
CN (2) CN104769415B (OSRAM)
AU (2) AU2013295679A1 (OSRAM)
BR (1) BR112015001592B1 (OSRAM)
CA (2) CA3198619A1 (OSRAM)
ES (1) ES2700498T3 (OSRAM)
IL (1) IL236819A0 (OSRAM)
MX (2) MX365089B (OSRAM)
SG (1) SG11201500347SA (OSRAM)
TW (2) TWI627393B (OSRAM)
WO (1) WO2014018805A2 (OSRAM)

Families Citing this family (118)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9619627B2 (en) 2011-09-25 2017-04-11 Theranos, Inc. Systems and methods for collecting and transmitting assay results
GB201210403D0 (en) * 2012-06-13 2012-07-25 Ffei Ltd Mircoscope colour chart
EP3495799B1 (en) 2012-07-25 2023-09-06 Labrador Diagnostics LLC A system for imaging a biological sample
US9513224B2 (en) 2013-02-18 2016-12-06 Theranos, Inc. Image analysis and measurement of biological samples
CA2901052C (en) * 2013-02-18 2023-10-03 Theranos, Inc. Image analysis and measurement of biological samples
US9562860B1 (en) 2013-06-19 2017-02-07 Theranos, Inc. Methods and devices for sample analysis
DE102013216124A1 (de) * 2013-08-14 2015-02-19 Carl Zeiss Microscopy Gmbh Hochauflösende 3D-Fluoreszenzmikroskopie
BR112016004955B1 (pt) 2013-09-06 2021-10-26 Labrador Diagnostics Llc Dispositivos, sistemas, métodos e conjuntos para receber cotonete
US9352315B2 (en) 2013-09-27 2016-05-31 Taiwan Semiconductor Manufacturing Company, Ltd. Method to produce chemical pattern in micro-fluidic structure
US9784670B1 (en) 2014-01-22 2017-10-10 Theranos, Inc. Unified detection system for fluorometry, luminometry and spectrometry
WO2015120147A1 (en) 2014-02-06 2015-08-13 Scanogen Inc. Detection units and methods for detecting a target analyte
EP2986891A4 (en) * 2014-04-04 2017-06-14 Bio-rad Laboratories, Inc. Annular illumination structure
US10661268B2 (en) * 2014-06-30 2020-05-26 Beacon Technologies, LLC Pipette tip system, device and method of use
US9574989B2 (en) * 2014-08-08 2017-02-21 Omnivision Technologies, Inc. Lens-free imaging system and method for detecting particles in sample deposited on image sensor
GB201506992D0 (en) * 2014-11-14 2015-06-10 Nplex Pty Ltd A portable in-vitro diagnostic detector
WO2016086023A1 (en) 2014-11-24 2016-06-02 Massachusetts Institute Of Technology Systems, apparatus, and methods for analyzing blood cell dynamics
TWI566742B (zh) * 2015-02-26 2017-01-21 華邦電子股份有限公司 分析處理裝置
US10408759B2 (en) * 2015-05-26 2019-09-10 Becton, Dickinson And Company Methods and systems for high resolution fluorescence microscopy of polymeric dye-labeled samples using polarized light
US10458902B2 (en) * 2015-09-13 2019-10-29 Australian Sensing and Indentification Systems Pty. Ltd. Analysis instrument, associated systems and methods
EP3368220B1 (en) 2015-10-26 2020-07-22 IDEXX Laboratories, Inc. Hematology test slide
CN105284240B (zh) * 2015-10-30 2017-10-03 山东省农作物种质资源中心 种子籽粒颜色分辨台及分辨方法
ES2871049T3 (es) * 2015-12-18 2021-10-28 Abbott Lab Método para determinar la identidad de tinciones histológicas
WO2017117553A1 (en) * 2015-12-31 2017-07-06 Mec Dynamics Micro mechanical methods and systems for performing assays
TWI568464B (zh) * 2016-02-05 2017-02-01 Guo-Zhi Liao Drug release and detection device, method of operation of drug release and detection device, and method for detecting fluorescent substance
US11054365B2 (en) * 2016-02-23 2021-07-06 Shimadzu Corporation Microscopic analysis device
EP3423881B1 (en) * 2016-03-01 2022-07-13 Molecular Devices, LLC Imaging system and method with scattering to reduce source auto-fluorescence and improve uniformity
JP6913323B2 (ja) * 2016-03-11 2021-08-04 株式会社ニコン 評価装置、観察装置、及びプログラム
WO2017159011A1 (ja) * 2016-03-15 2017-09-21 ソニー株式会社 情報処理装置、情報処理方法、プログラム及び情報処理システム
US10768406B2 (en) 2016-06-20 2020-09-08 Scanogen Inc. Imaging system
CN109313119B (zh) * 2016-06-20 2021-11-02 普莱尔股份公司 用于检测和/或表征流体携带的颗粒的装置和方法
US20190323939A1 (en) * 2016-06-22 2019-10-24 Kyocera Corporation Fine particle counter
WO2018009384A1 (en) * 2016-07-06 2018-01-11 Advanced Instruments, Llc Cuvette and rotor system for blood plasma separation
US10768105B1 (en) 2016-07-29 2020-09-08 Labrador Diagnostics Llc Image analysis and measurement of biological samples
TWI595372B (zh) 2016-08-31 2017-08-11 義守大學 用以檢測蛋白特徵物之顯微影像檢測系統以及顯微影像檢測方法
CN109791277A (zh) * 2016-09-29 2019-05-21 奥林巴斯株式会社 观察装置
JP6951349B2 (ja) * 2016-09-30 2021-10-20 オリンパス株式会社 観察装置
CN108226043B (zh) * 2016-12-22 2024-07-02 赛默飞世尔（上海）仪器有限公司 用于水质监测的测量单元及测量系统
CN106706643B (zh) * 2017-02-23 2019-07-02 马青山 一种肝癌对比切片检测方法
JP6938986B2 (ja) * 2017-03-15 2021-09-22 住友金属鉱山株式会社 粒子形状の評価方法
EP3612816B1 (en) 2017-04-20 2023-06-07 Biomerieux, Inc Method, apparatus, and computer program product for controlling components of a detection device
JP6911112B2 (ja) 2017-05-29 2021-07-28 オリンパス株式会社 観察装置
CA3079209A1 (en) 2017-10-16 2019-04-25 Massachusetts Institute Of Technology Systems, devices and methods for non-invasive hematological measurements
CN109697450B (zh) * 2017-10-20 2023-04-07 曦医生技股份有限公司 细胞分类方法
WO2019084513A1 (en) * 2017-10-26 2019-05-02 Essenlix Corporation QUICK MEASUREMENT OF PLATELETS
CN107976439B (zh) * 2017-12-06 2019-02-05 张哲� 一种检测血液和尿液样品的光学检测装置
JP6687656B2 (ja) 2018-03-19 2020-04-28 ファナック株式会社 検査装置およびその検査方法
CN112005277A (zh) * 2018-04-27 2020-11-27 惠普发展公司，有限责任合伙企业 三维体积成像
US11371986B2 (en) 2018-05-25 2022-06-28 Scanogen Inc. Detection units and methods for detecting a target analyte
NL2021377B1 (en) 2018-07-03 2020-01-08 Illumina Inc Interposer with first and second adhesive layers
US20200033260A1 (en) * 2018-07-25 2020-01-30 Pauleologos Cusulos Coagulation and aggregation refracted light indexing device and method
JP7166456B2 (ja) * 2018-08-01 2022-11-07 シーディーエックス・メディカル・アイピー・インコーポレイテッド 生体試料への拡張強化された合焦深度
SE542345C2 (en) 2018-08-03 2020-04-14 Redsense Medical Ab Device for measuring a property of a measurement object by luminescence
EP3611695A1 (en) * 2018-08-15 2020-02-19 Koninklijke Philips N.V. Generating annotation data of tissue images
JP7371098B2 (ja) 2018-08-17 2023-10-30 エンリッチ バイオシステムズ インコーポレイテッド 粒子および細胞を選択かつ単離するシステムおよび方法ならびにその使用
CN109084734B (zh) * 2018-08-17 2020-06-16 中国科学院自动化研究所 基于单目显微视觉的微球姿态测量装置及测量方法
CN109100352B (zh) * 2018-08-30 2024-07-23 天津港东科技股份有限公司 显微镜多功能液体测试装置
JP2022001889A (ja) * 2018-09-27 2022-01-06 富士フイルム株式会社 フォーカス位置評価装置、方法及びプログラム、並びに判別器
CN109583470A (zh) * 2018-10-17 2019-04-05 阿里巴巴集团控股有限公司 一种异常检测的解释特征确定方法和装置
CN115903205A (zh) * 2018-11-02 2023-04-04 豪洛捷公司 用于检视整个样本图像的系统
KR20210106024A (ko) 2019-01-22 2021-08-27 어플라이드 머티어리얼스, 인코포레이티드 확대된 이미지들의 캡처 및 저장
US10724956B1 (en) * 2019-02-01 2020-07-28 Essen Instruments, Inc. Spectral unmixing
KR102114135B1 (ko) 2019-02-28 2020-05-22 서강대학교산학협력단 현미경 장치 및 현미경 장치의 동작방법
CN110057730A (zh) * 2019-03-12 2019-07-26 天津大学 一种人体颗粒物主动吸入浓度测试方法
WO2020186029A1 (en) 2019-03-14 2020-09-17 Applied Materials, Inc. Identifying fiducial markers in microscope images
US11255785B2 (en) 2019-03-14 2022-02-22 Applied Materials, Inc. Identifying fiducial markers in fluorescence microscope images
EP3948226A4 (en) 2019-04-05 2023-09-06 Essenlix Corporation Assay accuracy and reliability improvement
JP7603050B2 (ja) * 2019-07-09 2024-12-19 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 自動迅速細胞診装置及び染色剤
CN114365024A (zh) * 2019-07-11 2022-04-15 感知力私人有限公司 基于机器学习的手机成像系统和分析方法
EP4003167B1 (en) 2019-07-24 2024-12-11 Massachusetts Institute of Technology Finger inserts for a nailfold imaging device
US11763920B2 (en) 2019-07-31 2023-09-19 Dig Labs Corporation Mucus analysis for animal health assessments
KR20220038698A (ko) * 2019-07-31 2022-03-29 디그 랩스 코퍼레이션 동물 건강 평가
CN110490882B (zh) * 2019-08-19 2022-12-27 腾讯科技（深圳）有限公司 细胞膜染色图像分析方法、装置及系统
MX2022003307A (es) * 2019-09-22 2022-04-12 Ecole Polytechnique Fed Lausanne Epfl Dispositivo y metodo para la valoracion del riesgo de nacimiento prematuro.
EP4035127A4 (en) 2019-09-24 2023-10-18 Applied Materials, Inc. INTERACTIVE TRAINING OF A MACHINE LEARNING MODEL FOR TISSUE SEGMENTATION
CN112630197B (zh) * 2019-10-10 2021-10-19 东北农业大学 一种判定蛋白质能否发生液-液相分离的方法
AU2020366521B2 (en) * 2019-10-19 2024-03-07 SequLITE Genomics US, Inc. Virtual fiducials
GB2588627B (en) * 2019-10-29 2023-03-29 Oxford Nanoimaging Ltd An optical imaging system
EP3836020B1 (en) * 2019-12-12 2024-08-28 National Cheng Kung University A method for determining cellular nuclear-to-cytoplasmic ratio
US20210182531A1 (en) 2019-12-17 2021-06-17 Applied Materials, Inc. Registration techniques for multiplexed fluorescence in-situ hybridization images
US10823662B1 (en) * 2020-02-18 2020-11-03 Horiba Instruments, Incorporated Special purpose cuvette assembly and method for optical microscopy of nanoparticle colloids
BR112022018102A2 (pt) * 2020-03-13 2022-11-22 Advanced Animal Diagnostics Inc Exibição móvel rápida e triagem para infecções e gravidade de infecção
WO2021190079A1 (zh) * 2020-03-27 2021-09-30 肯维捷斯（武汉）科技有限公司 一种显微成像的暗场照明器
EP4134725B1 (en) * 2020-04-08 2025-02-26 BGI Shenzhen Lens-free microscopic imaging system and method, and biochemical substance detection system and method
GB202006259D0 (en) * 2020-04-28 2020-06-10 Leeds Teaching Hospitals Nhs Trust Stain Assessment
US11925456B2 (en) 2020-04-29 2024-03-12 Hyperspectral Corp. Systems and methods for screening asymptomatic virus emitters
CN115699108A (zh) 2020-05-28 2023-02-03 露科实验室股份有限公司 一种从无创性毛细血管视频中检测白细胞和/或白细胞亚型的方法
WO2022009577A1 (ja) * 2020-07-06 2022-01-13 Ｌｏｏｋ Ｔｅｃ株式会社 血液測定装置
KR102331711B1 (ko) * 2020-08-21 2021-12-01 동아대학교 산학협력단 현장진료를 위한 미세유체칩 다중 채널 형광측정 장치
US12111257B2 (en) * 2020-08-26 2024-10-08 Honeywell International Inc. Fluid composition sensor device and method of using the same
JP7568212B2 (ja) * 2020-08-27 2024-10-16 リプロバイオ株式会社 精子運動性能評価システム及び精子運動性能評価方法
EP4528353A3 (de) * 2020-09-01 2025-09-17 BMG Labtech GmbH Autofokussystem für eine optische mess- oder mikroskopievorrichtung, verfahren zur fokuseinstellung bei einer optischen mess- oder mikroskopievorrichtung sowie optische mess- oder mikroskopievorrichtung
CN116783660A (zh) * 2020-10-08 2023-09-19 Essenlix 公司 减少测定错误
US12209964B2 (en) 2020-10-15 2025-01-28 Visera Technologies Company Limited Bio-chip, bio-detection system and bio-detection method
TWI767415B (zh) * 2020-11-18 2022-06-11 中國醫藥大學 自動化血液分析系統及自動化血液分析方法
CN112419295B (zh) * 2020-12-03 2024-08-23 腾讯科技（深圳）有限公司 医学图像处理方法、装置、计算机设备和存储介质
KR102501486B1 (ko) * 2020-12-10 2023-02-17 한국화학연구원 나노 입자 또는 나노 구조체에서 발생된 분광 신호 분석 시스템 및 분석 방법
CN214895849U (zh) 2021-01-28 2021-11-26 贝克曼库尔特生物科技（苏州）有限公司 气泡检测装置和样本处理仪
US20250270662A1 (en) * 2021-05-20 2025-08-28 Jason P. Gleghorn Method for enumeration and physical characterization of nanoparticles
EP4369297A4 (en) * 2021-08-10 2024-11-13 Lunit Inc. METHOD AND DEVICE FOR PRODUCING INFORMATION RELATING TO A PATHOLOGICAL SLIDE IMAGE
CN113790671B (zh) * 2021-09-03 2022-05-17 苏州天准科技股份有限公司 一种口径可调的落射光源及影像测量仪
CN118843819A (zh) * 2021-12-23 2024-10-25 雷迪奥米特医学公司 具有自适应光源组件的生物流体分析仪
JP2025502722A (ja) * 2021-12-23 2025-01-28 ラジオメーター・メディカル・アー・ペー・エス 光設定に基づく細胞分類による生体液分析器
TWI813145B (zh) * 2022-01-25 2023-08-21 佛教慈濟醫療財團法人 多重螢光組織影像分析方法及其系統
CA3243308A1 (en) * 2022-01-28 2023-08-03 University Of Southern California LIQUID BIOPSY ANALYTES TO DEFINE CANCER STAGES
CN116698707A (zh) * 2022-02-24 2023-09-05 杭州迅数科技有限公司 一种双光路双波长的光染色菌落成像装置
WO2023166655A1 (ja) * 2022-03-03 2023-09-07 オリンパス株式会社 照明ユニットおよび撮影システム
BR102023003038A2 (pt) * 2022-03-17 2024-01-02 Sysmex Corporation Método para classificar glóbulos brancos em subpopulações
CN114895449B (zh) * 2022-03-17 2023-06-23 华东师范大学 一种基于压缩感知的四维高速荧光显微成像装置
TWI798041B (zh) * 2022-03-31 2023-04-01 中原大學 用於執行全內反射散射量測的裝置與方法
KR102537348B1 (ko) * 2022-08-04 2023-05-30 한국기계연구원 디지털 pcr 분석용 기판 및 이의 제작방법
TWI866690B (zh) * 2023-02-07 2024-12-11 邦睿生技股份有限公司 生物樣品檢測裝置
TWI876356B (zh) * 2023-05-30 2025-03-11 天亮醫療器材股份有限公司 檢測管、檢測系統及待測體參數的光學檢測方法
TWI860738B (zh) * 2023-06-05 2024-11-01 崑山科技大學 染色輔助螢光影像偵測現地環境氯苯之方法
CN119394870A (zh) * 2023-07-21 2025-02-07 上海浚真生命科学有限公司 光学成像传感器和生物反应系统
WO2025128682A1 (en) * 2023-12-15 2025-06-19 Idexx Laboratories, Inc. Process and systems for autofocusing and measuring tilt of sample plane
WO2025137530A1 (en) * 2023-12-22 2025-06-26 Idexx Laboratories, Inc. Systems and methods for uniform oblique illumination for optical imaging
WO2025145095A1 (en) * 2023-12-29 2025-07-03 Beckman Coulter, Inc. Customized sample handling in biological analysis
KR102832369B1 (ko) * 2025-05-19 2025-07-14 (주)디로펫 정량적 위상 이미징 장치와 이를 이용한 비브리오패혈증 모니터링 방법

Family Cites Families (122)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4066362A (en) * 1968-08-16 1978-01-03 E. I. Du Pont De Nemours And Company Apparatus and method for performing photometric analysis
GB1382081A (en) * 1972-03-14 1975-01-29 Ici Ltd Transmission spectra
US3849654A (en) 1973-10-19 1974-11-19 H Malvin Fluorescence cuvette
US4305816A (en) * 1980-02-11 1981-12-15 Borden, Inc. Apparatus and method for inspecting containers
US5109429A (en) * 1985-11-04 1992-04-28 Cell Analysis Systems,Inc. Apparatus and method for analyses of biological specimens
US4868126A (en) 1985-12-11 1989-09-19 Flow Cytometry Standards Corporation Method of calibrating a fluorescent microscope using fluorescent calibration microbeads simulating stained cells
US4896966A (en) 1986-08-15 1990-01-30 Hamilton-Thorn Research Motility scanner and method
US5289255A (en) * 1991-03-28 1994-02-22 Minnesota Mining And Manufacturing Co. Cuvette for use in making a measurement of a blood parameter and assembly utilizing the same
JPH05240774A (ja) * 1992-03-02 1993-09-17 Hitachi Ltd 光学セル及び光学検出装置とこれを用いる試料分離検出装置
US5292484A (en) * 1992-07-16 1994-03-08 Spectrum Systems, Inc. Cuvette and cuvette cartridge for a chemical analyzer
US5585246A (en) * 1993-02-17 1996-12-17 Biometric Imaging, Inc. Method for preparing a sample in a scan capillary for immunofluorescent interrogation
EP0731951B1 (en) 1993-02-26 2000-07-05 E-Y Laboratories, Inc. Optical specimen analysis system and method
US5374531A (en) * 1993-03-22 1994-12-20 Zynaxis, Inc. Immunoassay for determination of cells
US5534416A (en) * 1993-04-13 1996-07-09 Molecular Probes, Inc. Fluorescent viability assay using cyclic-substituted unsymmetrical cyanine dyes
US5407638A (en) 1993-04-28 1995-04-18 Shell Oil Company Detector-cell adapted for continuous-flow absorption detection
WO1994028396A1 (en) 1993-05-28 1994-12-08 Fisons Plc Analytical apparatus
US5510621A (en) * 1994-10-03 1996-04-23 Optical Solutions, Inc. Apparatus and method for measuring components in a bag
US5869689A (en) * 1995-10-17 1999-02-09 Molecular Probes, Inc Stains for acidic organelles
AU2139597A (en) * 1996-05-13 1997-12-05 Dhc Analysis, Inc. Sampling device for spectrometric measurements
JP3322579B2 (ja) 1996-10-17 2002-09-09 株式会社エンプラス サイドライト型面光源装置
US7117098B1 (en) 1997-02-27 2006-10-03 Cellomics, Inc. Machine-readable storage medium for analyzing distribution of macromolecules between the cell membrane and the cell cytoplasm
JP4294740B2 (ja) * 1997-05-23 2009-07-15 ソレクサ・インコーポレイテッド 分析物の系列的プロセシングのためのシステムおよび装置
GB2326229A (en) * 1997-06-13 1998-12-16 Robert Jeffrey Geddes Carr Detecting and analysing submicron particles
DE19735119C2 (de) 1997-08-13 2000-05-18 Deutsches Krebsforsch Verfahren zur Fluoreszenzkorrelationsspektroskopie, insbesbesondere zur Mehrfarben-Fluoreszenzkorrelationsspektroskopie und Vorrichtung zur Durchführung des Verfahrens
US20030205681A1 (en) 1998-07-22 2003-11-06 Ljl Biosystems, Inc. Evanescent field illumination devices and methods
DE19801139B4 (de) 1998-01-14 2016-05-12 Till Photonics Gmbh Punktabtastendes Luminiszenz-Mikroskop
US6529835B1 (en) * 1998-06-25 2003-03-04 Caliper Technologies Corp. High throughput methods, systems and apparatus for performing cell based screening assays
SE9802558D0 (sv) 1998-07-16 1998-07-16 Hanning Instr Ab Device for detection of fluorescent
EP1123499A2 (en) * 1998-09-22 2001-08-16 Cellomics, Inc. Miniaturized cell array methods and apparatus for cell-based screening
US7450229B2 (en) 1999-01-25 2008-11-11 Amnis Corporation Methods for analyzing inter-cellular phenomena
US20020019062A1 (en) 1999-06-18 2002-02-14 Peter Lea Assay devices
JP3820806B2 (ja) 1999-07-21 2006-09-13 三菱電機株式会社 レーザ検査装置
WO2001008552A1 (en) 1999-08-03 2001-02-08 Biophysica, Llc Spectroscopic systems and methods for detecting tissue properties
IL131282A (en) 1999-08-05 2009-02-11 Orbotech Ltd Apparatus and methods for inspection of objects
DE10017823B4 (de) * 2000-04-10 2004-08-26 Till I.D. Gmbh Mikroskopische Beleuchtungsvorrichtung
US20030104494A1 (en) 2001-10-26 2003-06-05 Ilya Ravkin Assay systems with adjustable fluid communication
US20020192763A1 (en) * 2000-04-17 2002-12-19 Jiangchun Xu Compositions and methods for the therapy and diagnosis of prostate cancer
DE10029946A1 (de) 2000-06-17 2001-12-20 Merck Patent Gmbh Integrierte optische Wellenleiter für mikrofluidische Analysensysteme
US6599475B1 (en) 2000-09-27 2003-07-29 Becton, Dickinson And Company Apparatus for producing thin liquid samples for microscopic analysis
DE10124055A1 (de) 2001-05-16 2002-11-21 Fisher Rosemount Mfg Gmbh & Co Gerät zur optischen Untersuchung von Gasen
JP2003139687A (ja) * 2001-11-06 2003-05-14 Fuji Photo Film Co Ltd 測定チップ集合体および測定チップ取出し装置
JP3801914B2 (ja) * 2001-12-25 2006-07-26 富士写真フイルム株式会社 測定チップの再使用方法
US7756305B2 (en) * 2002-01-23 2010-07-13 The Regents Of The University Of California Fast 3D cytometry for information in tissue engineering
US20050153435A1 (en) 2002-02-14 2005-07-14 Solus Biosystems, Inc. Multiple sample screening using a silicon substrate
DK1493019T3 (da) * 2002-04-03 2006-12-18 Univ Jw Goethe Frankfurt Main Infraröd måleindretning, især til spektrometriske vandholdige systemer, fortrinsvis af flerkomponentsystemer
US6723288B2 (en) 2002-04-29 2004-04-20 Dade Behring Inc. Method of providing assay processing in a multi-analyzer system
US7354389B2 (en) * 2002-05-28 2008-04-08 Autogenomics, Inc. Microarray detector and methods
GB0216934D0 (en) * 2002-07-20 2002-08-28 Council Cent Lab Res Councils Optical apparatus
US7122384B2 (en) 2002-11-06 2006-10-17 E. I. Du Pont De Nemours And Company Resonant light scattering microparticle methods
JP2006507504A (ja) * 2002-11-22 2006-03-02 ソルス バイオシステムズ インコーポレーテッド 並列振動分光法による高スループットのスクリーニング
US20110259744A1 (en) * 2003-04-30 2011-10-27 Moyle William R Sensors for biomolecular detection and cell classification
EP1636017A2 (en) * 2003-05-20 2006-03-22 Fluidigm Corporation Method and system for microfluidic device and imaging thereof
US7545496B2 (en) 2003-06-25 2009-06-09 Koninklijke Philips Electronics N.V. Support with a surface structure for sensitive evanescent-field detection
EP1494007B8 (de) 2003-06-30 2014-09-24 Tecan Trading AG Vorrichtung und Verfahren zum Analysieren von Proben
AU2003904237A0 (en) * 2003-08-08 2003-08-21 Garvan Institute Of Medical Research Novel translocation assay
JP3879001B2 (ja) 2003-11-06 2007-02-07 独立行政法人情報通信研究機構 生物試料を高精度に測定する方法
KR20070004821A (ko) * 2004-03-11 2007-01-09 더 제너럴 하스피탈 코포레이션 형광 단백질을 사용하는 단층 촬영 영상을 위한 방법 및시스템
WO2005090945A1 (en) * 2004-03-16 2005-09-29 Amnis Corporation Method for imaging and differential analysis of cells
JP2005316383A (ja) * 2004-03-29 2005-11-10 Nikon Corp 蛍光顕微鏡
CN101069115B (zh) 2004-04-16 2010-05-12 奥本大学 显微镜照明装置及其适配器
EP2752874A1 (en) 2004-06-07 2014-07-09 Fluidigm Corporation Method and apparatus for imaging a device under temperature control
US8313713B2 (en) * 2004-06-17 2012-11-20 Ortho-Clinical Diagnostics, Inc. Stabilizing a cuvette during measurement
JP4363649B2 (ja) 2004-09-30 2009-11-11 富士フイルム株式会社 全反射減衰を利用した測定装置及び方法
JP2006162427A (ja) * 2004-12-07 2006-06-22 Toshiba Corp Ｌｅｄチップの検査方法及びｌｅｄチップの検査装置
US20060184040A1 (en) 2004-12-09 2006-08-17 Keller Kurtis P Apparatus, system and method for optically analyzing a substrate
US20060166305A1 (en) 2005-01-27 2006-07-27 Genetix Limited Animal cell confluence detection method and apparatus
KR20070107743A (ko) * 2005-01-31 2007-11-07 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 투과성 있는 혼탁한 매질 내의 입자들을 특성화하는 방법및 그 장치
US7344273B2 (en) 2005-03-22 2008-03-18 Binary Works, Inc. Ring light with user manipulable control
CA2610294C (en) 2005-05-09 2023-10-03 Theranos, Inc. Point-of-care fluidic systems and uses thereof
US7817273B2 (en) * 2005-06-30 2010-10-19 Life Technologies Corporation Two-dimensional spectral imaging system
JP2007127449A (ja) 2005-11-01 2007-05-24 Olympus Corp 測定容器
DE102005062439B3 (de) 2005-12-23 2007-05-10 JOMESA Meßsysteme GmbH Verfahren für die Partikelanalyse und Partikelanalysesystem
US8101368B2 (en) * 2006-02-13 2012-01-24 Dvs Sciences Inc. Quantitation of cellular DNA and cell numbers using element labeling
JP2007271360A (ja) * 2006-03-30 2007-10-18 Fujifilm Corp 測定装置及びセンサユニットの保持方法
US8007999B2 (en) 2006-05-10 2011-08-30 Theranos, Inc. Real-time detection of influenza virus
JP2007333497A (ja) * 2006-06-14 2007-12-27 Hitachi High-Technologies Corp 蛍光検出デバイスおよび装置
US8501099B2 (en) 2006-07-11 2013-08-06 The Curators Of The University Of Missouri Photo-acoustic detection device and method
CN101622522A (zh) * 2007-01-26 2010-01-06 贝克顿·迪金森公司 用于细胞计数和分析的方法、系统和组合物
US7936463B2 (en) 2007-02-05 2011-05-03 Palo Alto Research Center Incorporated Containing analyte in optical cavity structures
JP5286774B2 (ja) 2007-04-11 2013-09-11 株式会社ニコン 顕微鏡装置と、これに用いられる蛍光キューブ
US7808641B2 (en) * 2007-04-13 2010-10-05 C Technologies Inc. Interactive variable pathlength device
EP2012110A1 (en) * 2007-07-06 2009-01-07 Bp Oil International Limited Optical cell
US8158430B1 (en) 2007-08-06 2012-04-17 Theranos, Inc. Systems and methods of fluidic sample processing
US7952705B2 (en) * 2007-08-24 2011-05-31 Dynamic Throughput Inc. Integrated microfluidic optical device for sub-micro liter liquid sample microspectroscopy
JP5057377B2 (ja) * 2007-08-30 2012-10-24 国立大学法人埼玉大学 生体成分又はその機能の測定方法及び装置
KR101670621B1 (ko) 2007-10-02 2016-10-28 테라노스, 인코포레이티드 모듈러 현장 진료 장치 및 이의 용도
JP2011503536A (ja) * 2007-11-05 2011-01-27 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ マイクロエレクトロニクスセンサ
CN201156031Y (zh) 2008-02-02 2008-11-26 施慧勇 生化分析仪比色杯
CA2719012C (en) * 2008-03-21 2013-07-09 Abbott Point Of Care, Inc. Method and apparatus for detecting and counting platelets individually and in aggregate clumps
JP2011516833A (ja) * 2008-03-21 2011-05-26 アボット・ポイント・オブ・ケア 蛍光消光及び／又は蛍光退色を用いて個々の細胞又は粒状物質を分析するための方法及び装置
JPWO2009142312A1 (ja) * 2008-05-20 2011-09-29 株式会社ニコン 顕微鏡装置
JP2010060854A (ja) * 2008-09-04 2010-03-18 Nikon Corp 顕微鏡装置
JP2010091679A (ja) * 2008-10-06 2010-04-22 Nikon Corp 顕微鏡装置とこれに用いられる蛍光キューブ
JP2010091809A (ja) * 2008-10-08 2010-04-22 Nikon Corp 顕微鏡装置
US8576396B2 (en) 2008-11-19 2013-11-05 Postnova Analytics Gmbh Cell construction for light scatter detectors having self-focusing properties
US8329117B2 (en) 2009-05-14 2012-12-11 Canon U.S. Life Sciences, Inc. Microfluidic chip features for optical and thermal isolation
US8891086B2 (en) * 2009-06-15 2014-11-18 Thermo Scientific Portable Analytical Instruments Inc. Optical scanning systems and methods for measuring a sealed container with a layer for reducing diffusive scattering
JP2011118264A (ja) * 2009-12-07 2011-06-16 Nikon Corp 顕微鏡装置
US9134243B2 (en) 2009-12-18 2015-09-15 University Health Network System and method for sub-surface fluorescence imaging
EP2339327A1 (en) * 2009-12-23 2011-06-29 F. Hoffmann-La Roche AG Automatic test for imaging units
JP5344629B2 (ja) * 2010-04-30 2013-11-20 レーザーテック株式会社 検査装置及び検査方法
US20130088221A1 (en) * 2010-06-22 2013-04-11 Koninklijke Philips Electronics N.V. Detection of magnetic particles and their clustering
JP5703609B2 (ja) 2010-07-02 2015-04-22 ソニー株式会社 顕微鏡及び領域判定方法
TW201224425A (en) * 2010-12-03 2012-06-16 Microtek Int Inc Carrying device and method of containing specimen within the carrying device
KR20120080056A (ko) * 2011-01-06 2012-07-16 삼성전자주식회사 디스크 및 이를 이용한 검사장치의 보정방법
AR085087A1 (es) 2011-01-21 2013-09-11 Theranos Inc Sistemas y metodos para maximizar el uso de muestras
KR20220023960A (ko) 2011-03-07 2022-03-03 더 거버닝 카운실 오브 더 유니버시티 오브 토론토 미세유체기술을 이용한 휴대용 세포 검출 및 분석 방법 및 시스템
KR101158362B1 (ko) 2011-04-20 2012-06-22 한국과학기술원 세포 환경 내에서의 단일 분자 수준의 단백질-단백질 상호작용 분석 방법
US8934698B2 (en) 2011-06-22 2015-01-13 The Johns Hopkins University System and device for characterizing cells
US8380541B1 (en) 2011-09-25 2013-02-19 Theranos, Inc. Systems and methods for collecting and transmitting assay results
CN202514348U (zh) 2011-12-23 2012-11-07 鹤山健豪灯饰企业有限公司 具观赏生命成长过程的组合式小夜灯
US20140193892A1 (en) 2012-07-25 2014-07-10 Theranos, Inc. Image analysis and measurement of biological samples
US9513224B2 (en) 2013-02-18 2016-12-06 Theranos, Inc. Image analysis and measurement of biological samples
EP3495799B1 (en) 2012-07-25 2023-09-06 Labrador Diagnostics LLC A system for imaging a biological sample
US9497379B2 (en) 2013-08-22 2016-11-15 California Institute Of Technology Variable-illumination fourier ptychographic imaging devices, systems, and methods
CA2901052C (en) 2013-02-18 2023-10-03 Theranos, Inc. Image analysis and measurement of biological samples
US20150071541A1 (en) 2013-08-14 2015-03-12 Rice University Automated method for measuring, classifying, and matching the dynamics and information passing of single objects within one or more images
TWI496112B (zh) 2013-09-13 2015-08-11 Univ Nat Cheng Kung 細胞影像分割方法以及核質比評估方法
JP7118369B2 (ja) 2015-12-22 2022-08-16 株式会社エビデント 顕微鏡システム
US9930243B2 (en) 2016-05-02 2018-03-27 Mitutoyo Corporation Variable focal length imaging system
US10768406B2 (en) 2016-06-20 2020-09-08 Scanogen Inc. Imaging system
US10768105B1 (en) * 2016-07-29 2020-09-08 Labrador Diagnostics Llc Image analysis and measurement of biological samples

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