JP2015521593A5 - - Google Patents

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JP2015521593A5
JP2015521593A5 JP2015516723A JP2015516723A JP2015521593A5 JP 2015521593 A5 JP2015521593 A5 JP 2015521593A5 JP 2015516723 A JP2015516723 A JP 2015516723A JP 2015516723 A JP2015516723 A JP 2015516723A JP 2015521593 A5 JP2015521593 A5 JP 2015521593A5
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aqueous composition
cdr2
cdr3
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JP2015516723A
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Japanese (ja)
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JP2015521593A (ja
JP6265978B2 (ja
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Priority claimed from PCT/IB2013/054777 external-priority patent/WO2013186700A1/en
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Publication of JP2015521593A5 publication Critical patent/JP2015521593A5/ja
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JP2015516723A 2012-06-12 2013-06-11 抗体製剤 Active JP6265978B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261658472P 2012-06-12 2012-06-12
US61/658,472 2012-06-12
PCT/IB2013/054777 WO2013186700A1 (en) 2012-06-12 2013-06-11 Antibody formulation

Publications (3)

Publication Number Publication Date
JP2015521593A JP2015521593A (ja) 2015-07-30
JP2015521593A5 true JP2015521593A5 (enExample) 2016-06-16
JP6265978B2 JP6265978B2 (ja) 2018-01-24

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JP2015516723A Active JP6265978B2 (ja) 2012-06-12 2013-06-11 抗体製剤

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US (4) US9216219B2 (enExample)
EP (2) EP3593814B1 (enExample)
JP (1) JP6265978B2 (enExample)
KR (1) KR102124820B1 (enExample)
CN (1) CN104363920B (enExample)
AR (1) AR091413A1 (enExample)
AU (1) AU2013276112B2 (enExample)
BR (1) BR112014030820B1 (enExample)
CA (1) CA2875386C (enExample)
CL (1) CL2014003370A1 (enExample)
CO (1) CO7151487A2 (enExample)
CY (1) CY1122181T1 (enExample)
DK (1) DK2858671T3 (enExample)
EA (1) EA033373B1 (enExample)
EC (1) ECSP15017314A (enExample)
ES (1) ES2751659T3 (enExample)
GT (1) GT201400285A (enExample)
HR (1) HRP20191827T1 (enExample)
HU (1) HUE045523T2 (enExample)
IL (1) IL235966B (enExample)
LT (1) LT2858671T (enExample)
MA (1) MA37616A1 (enExample)
MX (1) MX363380B (enExample)
MY (1) MY179818A (enExample)
NZ (1) NZ630885A (enExample)
PE (1) PE20150200A1 (enExample)
PH (1) PH12014502778A1 (enExample)
PL (1) PL2858671T3 (enExample)
PT (1) PT2858671T (enExample)
SG (1) SG11201408174UA (enExample)
SI (1) SI2858671T1 (enExample)
TN (1) TN2014000488A1 (enExample)
TW (1) TWI653983B (enExample)
WO (1) WO2013186700A1 (enExample)
ZA (1) ZA201408547B (enExample)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS62853B1 (sr) 2010-01-06 2022-02-28 Takeda Pharmaceuticals Co Proteini koji vezuju kalikrein plazme
US9458240B2 (en) 2010-12-10 2016-10-04 Novartis Pharma Ag Anti-BAFFR antibody formulations
AU2012204202A1 (en) 2011-01-06 2013-07-11 Dyax Corp. Plasma kallikrein binding proteins
US9216219B2 (en) 2012-06-12 2015-12-22 Novartis Ag Anti-BAFFR antibody formulation
TWI660972B (zh) 2012-09-10 2019-06-01 愛爾蘭商尼歐托普生物科學公司 抗ｍｃａｍ抗體及相關使用方法
CA3208188A1 (en) 2013-03-15 2014-09-25 Takeda Pharmaceutical Company Limited Anti-plasma kallikrein antibodies
US10513555B2 (en) * 2013-07-04 2019-12-24 Prothena Biosciences Limited Antibody formulations and methods
CN104730237A (zh) * 2013-12-23 2015-06-24 国家纳米科学中心 试纸及其应用以及检测甲胎蛋白抗原、乙肝表面抗原或HIV的gp41抗体的方法
PT3096798T (pt) 2014-01-21 2021-02-25 Dyax Corp Proteínas de ligação à calicreína plasmática e seus usos no tratamento de angioedema hereditário
CA2938933A1 (en) 2014-03-12 2015-09-17 Prothena Biosciences Limited Anti-laminin4 antibodies specific for lg4-5
JP6728053B2 (ja) 2014-03-12 2020-07-22 プロセナ バイオサイエンシーズ リミテッド 抗ｍｃａｍ抗体及び関連する使用方法
AU2015235967B2 (en) 2014-03-27 2020-10-22 Takeda Pharmaceutical Company Limited Compositions and methods for treatment of diabetic macular edema
KR101597037B1 (ko) 2014-06-26 2016-02-24 엘지디스플레이 주식회사 구동소자의 전기적 특성 편차를 보상할 수 있는 유기발광 표시장치
TWI761959B (zh) 2014-11-07 2022-04-21 瑞士商諾華公司 治療眼部疾病之方法
US10464999B2 (en) 2015-01-28 2019-11-05 Prothena Biosciences Limited Anti-transthyretin antibodies
IL305207A (en) * 2015-03-30 2023-10-01 Takeda Pharmaceuticals Co Plasma kallikrein inhibitors and their uses to prevent the outbreak of hereditary angioedema
WO2017046776A2 (en) * 2015-09-16 2017-03-23 Prothena Biosciences Limited Use of anti-mcam antibodies for treatment or prophylaxis of giant cell arteritis, polymyalgia rheumatica or takayasu's arteritis
DK3386541T3 (da) * 2015-12-07 2020-09-28 Merck Patent Gmbh Vandig farmaceutisk formulering omfattende anti-pd-1-antistof avelumab
CN116077648A (zh) 2015-12-11 2023-05-09 武田药品工业株式会社 血浆激肽释放酶抑制剂及其治疗遗传性血管性水肿发作的用途
MX2018007520A (es) * 2015-12-18 2018-08-01 Astellas Pharma Inc Composicion farmaceutica que comprende un anticuerpo receptor de linfopoyetina estromal timica antihumano.
MX392862B (es) * 2016-06-16 2025-03-24 Janssen Vaccines & Prevention Bv Formulación de vacuna contra el vih.
KR102617264B1 (ko) 2016-10-19 2023-12-29 인벤라 인코포레이티드 항체 구조물
JP7681879B2 (ja) 2016-12-22 2025-05-23 ウニヴェルシタ・デリ・ストゥディ・マニャ・グレチア・カタンツァーロ Ｃｄ４３の固有のシアログリコシル化がん関連エピトープを標的化するモノクローナル抗体
CN110366429B (zh) * 2017-03-01 2024-10-11 免疫医疗有限公司 单克隆抗体的配制品
WO2018162446A1 (en) * 2017-03-06 2018-09-13 Merck Patent Gmbh Aqueous anti-pd-l1 antibody formulation
US11639391B2 (en) * 2017-04-18 2023-05-02 Dr. Reddy's Laboratories Limited Stable liquid pharmaceutical composition
JOP20190260A1 (ar) * 2017-05-02 2019-10-31 Merck Sharp & Dohme صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
KR20230066126A (ko) * 2017-07-27 2023-05-12 알렉시온 파마슈티칼스, 인코포레이티드 고농도 항-c5 항체 제형
EP4233901A3 (en) * 2017-08-22 2023-09-06 Biogen MA Inc. Pharmaceutical compositions containing anti-beta amyloid antibodies
WO2019071206A1 (en) 2017-10-06 2019-04-11 Prothena Biosciences Limited METHODS OF DETECTING TRANSTHYRETIN
MX2020005433A (es) * 2017-11-29 2020-08-27 Prothena Biosciences Ltd Formulacion liofilizada de un anticuerpo monoclonal contra la transtirretina.
CA3102349A1 (en) 2018-06-05 2019-12-12 King's College London Btnl3/8 targeting constructs for delivery of payloads to the gastrointestinal system
WO2020006266A1 (en) 2018-06-28 2020-01-02 Alexion Pharmaceuticals, Inc. Methods of producing anti-c5 antibodies
MX2021007393A (es) * 2018-12-18 2021-09-23 Novartis Ag Formulacion de solucion de proteinas que contiene una alta concentracion de un anticuerpo anti-vegf.
SG11202108627SA (en) 2019-02-18 2021-09-29 Lilly Co Eli Therapeutic antibody formulation
EP3932426A4 (en) * 2019-02-26 2022-12-14 Innovent Biologics (Suzhou) Co., Ltd. PREPARATIONS CONTAINING AN ANTI-CD47 ANTIBODY, METHOD FOR THE PREPARATION AND USE THEREOF
EP4055047A1 (en) 2019-11-06 2022-09-14 Novartis AG Treatment for sjögren's syndrome
WO2021136274A1 (zh) * 2019-12-30 2021-07-08 百奥泰生物制药股份有限公司 含抗Trop2抗体-药物偶联物的制剂及其制备方法和应用
MX2022008649A (es) 2020-01-13 2022-09-23 Takeda Pharmaceuticals Co Inhibidores de calicreina plasmatica y sus usos para tratar episodios de angioedema hereditario pediatrico.
EP4094777A4 (en) * 2020-01-21 2024-01-24 Innovent Biologics (Suzhou) Co., Ltd. RECOMBINANT FULLY HUMAN MONOCLONAL ANTI-TIGITE ANTIBODIES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF
CN116096414A (zh) * 2020-08-04 2023-05-09 诺华股份有限公司 Cll的治疗
WO2022031567A1 (en) 2020-08-04 2022-02-10 Novartis Ag Treatment of b cell malignancies
CA3204307A1 (en) * 2020-12-17 2022-06-23 Astrazeneca Ab Anti-il5r antibody formulations
CN115073598B (zh) * 2021-03-15 2024-02-20 盛禾(中国)生物制药有限公司 一种抗baffr抗体及其应用
EP4334351A1 (en) 2021-05-04 2024-03-13 Novartis AG Treatment for systemic lupus erythematosus using anti-baffr antibodies
CN117203240A (zh) 2021-05-04 2023-12-08 诺华股份有限公司 使用抗baffr抗体治疗狼疮肾炎
CA3233246A1 (en) * 2021-09-29 2023-04-06 Dragonfly Therapeutics, Inc. Antibodies targeting baff-r and use thereof
CN120548195A (zh) 2022-11-07 2025-08-26 上游生物公司 包含抗人类tslp受体抗体的药物组合物和其使用方法
CN118681009A (zh) * 2023-03-21 2024-09-24 百奥泰生物制药股份有限公司 一种复方制剂及其应用
CN116712390B (zh) * 2023-08-04 2023-11-14 上海览屹医药科技有限公司 一种高浓度高稳定性的抗体制剂及其制备方法
WO2025257781A1 (en) * 2024-06-14 2025-12-18 Novartis Ag Treatment of systemic sclerosis using anti-baff-r antibodies
WO2025263459A1 (ja) * 2024-06-17 2025-12-26 学校法人神戸薬科大学 バイオ医薬品組成物

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0154316B1 (en) 1984-03-06 1989-09-13 Takeda Chemical Industries, Ltd. Chemically modified lymphokine and production thereof
JP2989002B2 (ja) 1988-12-22 1999-12-13 キリン―アムジエン・インコーポレーテツド 化学修飾顆粒球コロニー刺激因子
US20020077461A1 (en) * 1996-04-24 2002-06-20 Soren Bjorn Pharmaceutical formulation
US6171586B1 (en) 1997-06-13 2001-01-09 Genentech, Inc. Antibody formulation
ES2434961T5 (es) 1998-04-20 2018-01-18 Roche Glycart Ag Ingeniería de glicosilación de anticuerpos para mejorar la citotoxicidad celular dependiente del anticuerpo
EP1176195B1 (en) 1999-04-09 2013-05-22 Kyowa Hakko Kirin Co., Ltd. Method for controlling the activity of immunologically functional molecule
CA2375527A1 (en) 1999-06-23 2000-12-28 Oregon Health And Science University Method for enhancing hematopoiesis
AU2001276842B2 (en) 2000-06-28 2007-04-26 Glycofi, Inc. Methods for producing modified glycoproteins
US20030157108A1 (en) 2001-10-25 2003-08-21 Genentech, Inc. Glycoprotein compositions
IL161677A0 (en) 2001-11-08 2004-09-27 Protein Design Labs Stable liquid pharmaceutical formulation of igg antibodies
EP3210624A1 (en) 2002-02-27 2017-08-30 Immunex Corporation Stabilized tnfr-fc composition comprising arginine
AU2003293543A1 (en) 2002-12-13 2004-07-09 Abgenix, Inc. System and method for stabilizing antibodies with histidine
JO3000B1 (ar) 2004-10-20 2016-09-05 Genentech Inc مركبات أجسام مضادة .
CN101120021A (zh) * 2004-12-31 2008-02-06 基因技术公司 结合br3的多肽及其用途
MX2011000616A (es) * 2008-07-17 2011-02-24 Novartis Ag Composiciones y metodos de uso para anticuerpos terapeuticos.
KR101614983B1 (ko) * 2009-11-17 2016-04-22 입센 파마 에스.에이.에스 Ｈｇｈ 및 ｒｈｉｇｆ―１의 조합물을 위한 제제
US9458240B2 (en) * 2010-12-10 2016-10-04 Novartis Pharma Ag Anti-BAFFR antibody formulations
US20140335084A1 (en) 2011-12-06 2014-11-13 Hoffmann-La Roche Inc. Antibody formulation
US9216219B2 (en) 2012-06-12 2015-12-22 Novartis Ag Anti-BAFFR antibody formulation

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