JP2015517402A5 - - Google Patents
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- JP2015517402A5 JP2015517402A5 JP2015512799A JP2015512799A JP2015517402A5 JP 2015517402 A5 JP2015517402 A5 JP 2015517402A5 JP 2015512799 A JP2015512799 A JP 2015512799A JP 2015512799 A JP2015512799 A JP 2015512799A JP 2015517402 A5 JP2015517402 A5 JP 2015517402A5
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- Prior art keywords
- butyl
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- ethyl
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- 238000000034 method Methods 0.000 claims 24
- 125000000217 alkyl group Chemical group 0.000 claims 16
- 239000000463 material Substances 0.000 claims 12
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims 11
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 10
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 10
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 10
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 10
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 claims 10
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 9
- 230000005526 G1 to G0 transition Effects 0.000 claims 9
- 239000011148 porous material Substances 0.000 claims 9
- 235000013877 carbamide Nutrition 0.000 claims 7
- 239000011162 core material Substances 0.000 claims 7
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 6
- 150000001408 amides Chemical class 0.000 claims 6
- 125000003118 aryl group Chemical group 0.000 claims 6
- 125000000524 functional group Chemical group 0.000 claims 6
- 125000000623 heterocyclic group Chemical group 0.000 claims 6
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 claims 6
- 230000014759 maintenance of location Effects 0.000 claims 6
- 150000003568 thioethers Chemical class 0.000 claims 6
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 claims 6
- 150000003852 triazoles Chemical class 0.000 claims 6
- 150000002148 esters Chemical class 0.000 claims 5
- 125000001153 fluoro group Chemical group F* 0.000 claims 5
- 239000001257 hydrogen Substances 0.000 claims 5
- 229910052739 hydrogen Inorganic materials 0.000 claims 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 4
- 150000001412 amines Chemical class 0.000 claims 4
- 239000004202 carbamide Substances 0.000 claims 4
- 238000004587 chromatography analysis Methods 0.000 claims 4
- 150000002431 hydrogen Chemical class 0.000 claims 4
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 claims 3
- 238000010485 C−C bond formation reaction Methods 0.000 claims 3
- GNVMUORYQLCPJZ-UHFFFAOYSA-M Thiocarbamate Chemical compound NC([S-])=O GNVMUORYQLCPJZ-UHFFFAOYSA-M 0.000 claims 3
- 239000012491 analyte Substances 0.000 claims 3
- 150000004657 carbamic acid derivatives Chemical class 0.000 claims 3
- 150000004649 carbonic acid derivatives Chemical class 0.000 claims 3
- 150000002170 ethers Chemical class 0.000 claims 3
- 125000005842 heteroatom Chemical group 0.000 claims 3
- 150000003949 imides Chemical class 0.000 claims 3
- 125000003010 ionic group Chemical group 0.000 claims 3
- 239000002245 particle Substances 0.000 claims 3
- 125000000475 sulfinyl group Chemical group [*:2]S([*:1])=O 0.000 claims 3
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 claims 3
- 150000003462 sulfoxides Chemical class 0.000 claims 3
- 239000002344 surface layer Substances 0.000 claims 3
- 150000003672 ureas Chemical class 0.000 claims 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 2
- BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical compound [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 claims 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical group O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 2
- -1 cyano, hydroxyl Chemical group 0.000 claims 2
- FDYPWIDITZJTAI-UHFFFAOYSA-N n-ethyl-n-trimethoxysilylethanamine Chemical compound CCN(CC)[Si](OC)(OC)OC FDYPWIDITZJTAI-UHFFFAOYSA-N 0.000 claims 2
- 229910052757 nitrogen Inorganic materials 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- 239000001301 oxygen Substances 0.000 claims 2
- 229910000077 silane Inorganic materials 0.000 claims 2
- 229910052717 sulfur Inorganic materials 0.000 claims 2
- 239000011593 sulfur Substances 0.000 claims 2
- XVZMLSWFBPLMEA-UHFFFAOYSA-N trimethoxy(2-pyridin-2-ylethyl)silane Chemical compound CO[Si](OC)(OC)CCC1=CC=CC=N1 XVZMLSWFBPLMEA-UHFFFAOYSA-N 0.000 claims 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 150000001298 alcohols Chemical class 0.000 claims 1
- 229920001400 block copolymer Polymers 0.000 claims 1
- 229910002092 carbon dioxide Inorganic materials 0.000 claims 1
- 239000001569 carbon dioxide Substances 0.000 claims 1
- 238000013375 chromatographic separation Methods 0.000 claims 1
- 150000002009 diols Chemical class 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 229910010272 inorganic material Inorganic materials 0.000 claims 1
- 239000011147 inorganic material Substances 0.000 claims 1
- 230000003993 interaction Effects 0.000 claims 1
- 230000001788 irregular Effects 0.000 claims 1
- 239000010410 layer Substances 0.000 claims 1
- 150000004706 metal oxides Chemical group 0.000 claims 1
- 230000000116 mitigating effect Effects 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- XIQGSQJCEPBGBB-UHFFFAOYSA-N nitrooxy-N-oxoboronamidic acid Chemical compound [N+](=O)([O-])OB(O)N=O XIQGSQJCEPBGBB-UHFFFAOYSA-N 0.000 claims 1
- 125000003107 substituted aryl group Chemical group 0.000 claims 1
- 238000004808 supercritical fluid chromatography Methods 0.000 claims 1
- 239000004753 textile Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261647303P | 2012-05-15 | 2012-05-15 | |
| US61/647,303 | 2012-05-15 | ||
| PCT/US2013/041207 WO2013173494A1 (en) | 2012-05-15 | 2013-05-15 | Chromatographic materials |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015517402A JP2015517402A (ja) | 2015-06-22 |
| JP2015517402A5 true JP2015517402A5 (enExample) | 2016-06-30 |
Family
ID=49584263
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015512799A Pending JP2015517402A (ja) | 2012-05-15 | 2013-05-15 | クロマトグラフィー材料 |
| JP2015512802A Expired - Fee Related JP6401151B2 (ja) | 2012-05-15 | 2013-05-15 | クロマトグラフィー材料 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015512802A Expired - Fee Related JP6401151B2 (ja) | 2012-05-15 | 2013-05-15 | クロマトグラフィー材料 |
Country Status (8)
| Country | Link |
|---|---|
| US (9) | US9925521B2 (enExample) |
| EP (1) | EP3113857B1 (enExample) |
| JP (2) | JP2015517402A (enExample) |
| CN (3) | CN107754776B (enExample) |
| DE (2) | DE112013002519T5 (enExample) |
| GB (3) | GB2515984A (enExample) |
| HK (1) | HK1211258A1 (enExample) |
| WO (3) | WO2013173494A1 (enExample) |
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| US10119944B2 (en) | 2013-12-24 | 2018-11-06 | Waters Technologies Corporation | Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides |
| JP6821435B2 (ja) * | 2014-03-01 | 2021-01-27 | ウオーターズ・テクノロジーズ・コーポレイシヨン | 不飽和分子を分離するためのクロマトグラフィー材料 |
| WO2016011427A1 (en) * | 2014-07-17 | 2016-01-21 | Azyp, Llc | High efficiency, ultra-stable, bonded hydrophilic interaction chromatography (hilic) matrix on superficially porous particles (spps) |
| US10246410B2 (en) | 2014-12-03 | 2019-04-02 | Life Technologies Corporation | Hydrazinyl and aminooxy compounds and their methods of use |
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| US20180057553A1 (en) * | 2015-03-05 | 2018-03-01 | The University Of Tokyo | Conjugate and use thereof |
| CN108136275A (zh) * | 2015-04-29 | 2018-06-08 | 沃特世科技公司 | 用于超临界流体色谱法的包含离子配对键合相的高纯度色谱材料 |
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| CN105727912B (zh) * | 2016-04-07 | 2018-08-17 | 湖北省农业科学院农业质量标准与检测技术研究所 | 一种新型胆固醇键合硅胶固定相及其制备方法和应用 |
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| EP3964287A1 (en) * | 2009-06-01 | 2022-03-09 | Waters Technologies Corporation | Hybrid material for chromatographic separations |
| IN2012DN00363A (enExample) * | 2009-08-04 | 2015-08-21 | Waters Technologies Corp | |
| GB2473814B (en) * | 2009-09-16 | 2014-06-11 | Spheritech Ltd | Hollow particulate support |
| EP2488544B1 (en) * | 2009-10-15 | 2015-03-18 | Monash University | Affinity ligands and methods for protein purification |
| US20130135610A1 (en) * | 2009-12-15 | 2013-05-30 | Waters Technologies Corporation | Device and methods for performing size exclusion chromatography |
| JP6199184B2 (ja) | 2010-07-26 | 2017-09-20 | ウオーターズ・テクノロジーズ・コーポレイシヨン | 粒度分布の狭い実質的に非多孔質のコアを含む表面多孔質材料、その製造方法及びクロマトグラフィー分離用としてのその使用 |
| AU2011285520A1 (en) | 2010-08-06 | 2013-03-07 | Molycorp Minerals Llc | Agglomeration of high surface area rare earths |
| WO2013173494A1 (en) * | 2012-05-15 | 2013-11-21 | Waters Technologies Corporation | Chromatographic materials |
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2013
- 2013-05-15 WO PCT/US2013/041207 patent/WO2013173494A1/en not_active Ceased
- 2013-05-15 DE DE112013002519.1T patent/DE112013002519T5/de not_active Ceased
- 2013-05-15 US US14/401,385 patent/US9925521B2/en active Active
- 2013-05-15 JP JP2015512799A patent/JP2015517402A/ja active Pending
- 2013-05-15 GB GB1420328.5A patent/GB2515984A/en not_active Withdrawn
- 2013-05-15 GB GB1718598.4A patent/GB2553727B/en active Active
- 2013-05-15 CN CN201711077635.1A patent/CN107754776B/zh active Active
- 2013-05-15 GB GB1420330.1A patent/GB2521524B/en active Active
- 2013-05-15 DE DE112013002532.9T patent/DE112013002532T5/de active Pending
- 2013-05-15 US US14/401,340 patent/US20150136700A1/en not_active Abandoned
- 2013-05-15 JP JP2015512802A patent/JP6401151B2/ja not_active Expired - Fee Related
- 2013-05-15 HK HK15112033.7A patent/HK1211258A1/xx unknown
- 2013-05-15 CN CN201380037761.8A patent/CN104428045B/zh active Active
- 2013-05-15 WO PCT/US2013/041221 patent/WO2013173501A2/en not_active Ceased
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2014
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