HK1211258A1 - Chromatographic materials - Google Patents

Chromatographic materials

Info

Publication number
HK1211258A1
HK1211258A1 HK15112033.7A HK15112033A HK1211258A1 HK 1211258 A1 HK1211258 A1 HK 1211258A1 HK 15112033 A HK15112033 A HK 15112033A HK 1211258 A1 HK1211258 A1 HK 1211258A1
Authority
HK
Hong Kong
Prior art keywords
chromatographic materials
chromatographic
materials
Prior art date
Application number
HK15112033.7A
Other languages
English (en)
Chinese (zh)
Inventor
Kevin D Wyndham
Michael F Morris
Darryl W Brousmiche
Jason F Hill
Jacob Nathan Fairchild
Original Assignee
Waters Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Waters Technologies Corp filed Critical Waters Technologies Corp
Publication of HK1211258A1 publication Critical patent/HK1211258A1/xx

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    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
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    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282Porous sorbents
    • B01J20/283Porous sorbents based on silica
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Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111644164B (zh) * 2012-05-15 2024-03-08 沃特世科技公司 用于分离不饱和分子的色谱材料
WO2013173494A1 (en) 2012-05-15 2013-11-21 Waters Technologies Corporation Chromatographic materials
US9719970B2 (en) * 2012-11-30 2017-08-01 Waters Technologies Corporation Methods and apparatus for the analysis of vitamin D metabolites
EP3007792A4 (en) 2013-06-11 2017-05-03 Waters Technologies Corporation Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography
US9518960B2 (en) * 2013-10-02 2016-12-13 Waters Technologies Corporation System and method for rapid analysis of polycyclic aromatic hydrocarbons
US11092574B2 (en) 2013-12-24 2021-08-17 Waters Technologies Corporation Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides
US10119944B2 (en) 2013-12-24 2018-11-06 Waters Technologies Corporation Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides
JP6821435B2 (ja) * 2014-03-01 2021-01-27 ウオーターズ・テクノロジーズ・コーポレイシヨン 不飽和分子を分離するためのクロマトグラフィー材料
WO2016011427A1 (en) * 2014-07-17 2016-01-21 Azyp, Llc High efficiency, ultra-stable, bonded hydrophilic interaction chromatography (hilic) matrix on superficially porous particles (spps)
EP3227264B1 (en) 2014-12-03 2020-10-21 Life Technologies Corporation Hydrazinyl and aminooxy compounds and their methods of use
US10309959B2 (en) 2014-12-03 2019-06-04 Life Technologies Corporation Charged reactive oligomers
US20180057553A1 (en) * 2015-03-05 2018-03-01 The University Of Tokyo Conjugate and use thereof
CN108136275A (zh) * 2015-04-29 2018-06-08 沃特世科技公司 用于超临界流体色谱法的包含离子配对键合相的高纯度色谱材料
CN105536747B (zh) * 2016-01-14 2018-02-02 重庆大学 一种智能响应液相色谱填料及其制备方法
WO2017155870A1 (en) 2016-03-06 2017-09-14 Waters Technologies Corporation Superficially porous materials comprising a coated core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations
JP6813247B2 (ja) * 2016-03-23 2021-01-13 株式会社ダイセル クロマトグラフィー用の固定相
CN105727912B (zh) * 2016-04-07 2018-08-17 湖北省农业科学院农业质量标准与检测技术研究所 一种新型胆固醇键合硅胶固定相及其制备方法和应用
CN109154604B (zh) * 2016-04-24 2023-07-21 沃特世科技公司 用于对用两亲强碱性部分改性的聚糖进行分析的带电表面反相色谱材料方法
WO2018023005A1 (en) * 2016-07-28 2018-02-01 Waters Technologies Corporation Encapsulated pre-analytic workflows for flow-through devices, liquid chromatography and mass spectrometric analysis
RU2638660C1 (ru) * 2016-12-19 2017-12-15 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Сорбент для определения соединений ионной и гидрофильной природы
CN110383060A (zh) 2017-03-08 2019-10-25 沃特世科技公司 使用色谱法确定极性农药
CN116651422A (zh) * 2017-03-16 2023-08-29 沃特世科技公司 色谱组合物
CN110709696B (zh) * 2017-06-22 2022-01-04 昭和电工株式会社 寡核苷酸的混合物的分离分析方法
US11709156B2 (en) 2017-09-18 2023-07-25 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved analytical analysis
US11709155B2 (en) 2017-09-18 2023-07-25 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes
US20190092800A1 (en) 2017-09-26 2019-03-28 Waters Technologies Corporation Liquid chromatographic separation of carbohydrate tautomers
CN108061773B (zh) * 2018-02-02 2019-04-12 湖南山水检测有限公司 高效液相色谱技术测定维生素a的方法
CN110412139A (zh) 2018-04-27 2019-11-05 株式会社岛津制作所 一种分析系统
US11173418B2 (en) 2018-07-11 2021-11-16 Waters Technologies Corporation Materials and methods for trap-elute mixed mode chromatography
CN109692501B (zh) * 2018-12-29 2021-02-09 武汉谱立科技有限公司 一种色谱柱及其制备方法和应用
US11994499B2 (en) * 2019-02-27 2024-05-28 Waters Technologies Corporation Coated flow path components for chromatographic effects
JP7156146B2 (ja) * 2019-04-10 2022-10-19 株式会社島津製作所 親水性材料の疎水化方法
EP3744683A1 (en) * 2019-05-29 2020-12-02 Nouryon Chemicals International B.V. Porous silica particles
EP3744684A1 (en) 2019-05-29 2020-12-02 Nouryon Chemicals International B.V. Porous silica particles
WO2020242751A1 (en) 2019-05-30 2020-12-03 Restek Corporation Hybrid ligand and liquid chromatography stationary phase including hybrid ligand
CN111250064A (zh) * 2019-10-10 2020-06-09 浙江海洋大学 一种支化聚乙烯亚胺修饰贻贝壳粉的制备方法及应用
CN110938458B (zh) * 2019-11-19 2021-11-23 中海油天津化工研究设计院有限公司 一种生产高品质工业白油的方法
CN110938459B (zh) * 2019-11-19 2021-09-28 中海油天津化工研究设计院有限公司 一种石脑油生产石油醚及轻质白油的方法
CN111013557B (zh) * 2019-12-27 2023-04-07 纳谱分析技术(苏州)有限公司 一种疏水层析介质及其制备方法和应用
US20210255196A1 (en) * 2020-01-17 2021-08-19 Waters Technologies Corporation Low binding surfaces for peptide mapping
US11918936B2 (en) 2020-01-17 2024-03-05 Waters Technologies Corporation Performance and dynamic range for oligonucleotide bioanalysis through reduction of non specific binding
CN112147249B (zh) * 2020-09-25 2022-04-12 安徽瑞思威尔科技有限公司 一种杨梅酒中31种有效成分的UPC2-PDA-Q-Tof/MS检测方法
CN112755985B (zh) * 2020-12-28 2023-08-25 纳谱分析技术(苏州)有限公司 一种液相色谱分离介质及其制备方法和应用
GB202108373D0 (en) * 2021-06-11 2021-07-28 Johnson Matthey Plc Separation of base metals
CN114377566B (zh) * 2021-12-25 2022-09-20 广东台泉环保科技有限公司 一种盐湖提锂用纳滤膜及其制备方法
CN117269375B (zh) * 2023-11-22 2024-02-13 湖南科锐斯医药科技有限公司 一种测定维生素a醋酸酯粉中有关物质的方法

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2357184A1 (de) 1973-11-16 1975-05-22 Merck Patent Gmbh Verfahren zur herstellung von organisch modifizierten siliciumdioxiden
ZA814216B (en) * 1980-06-27 1982-07-28 Akzo Nv Porous inorganic support material coated with an organic stationary phase for use in chromatography and process for its preparation
JP2504005B2 (ja) * 1986-11-17 1996-06-05 東ソー株式会社 充填剤およびその製法
US4767670A (en) 1987-01-21 1988-08-30 E. I. Du Pont De Nemours And Company Chromatographic supports for separation of oligonucleotides
US5374755A (en) 1992-07-17 1994-12-20 Millipore Corporation Liquid chromatography stationary phases with reduced silanol interactions
EP1733786B1 (en) * 1999-02-05 2010-04-14 Waters Technologies Corporation Porous hybrid particles for chromatographic separations
US6686035B2 (en) 1999-02-05 2004-02-03 Waters Investments Limited Porous inorganic/organic hybrid particles for chromatographic separations and process for their preparation
SE0004932D0 (sv) 2000-12-31 2000-12-31 Apbiotech Ab A method for mixed mode adsorption and mixed mode adsorbents
US6528167B2 (en) 2001-01-31 2003-03-04 Waters Investments Limited Porous hybrid particles with organic groups removed from the surface
US7250214B2 (en) 2001-08-09 2007-07-31 Waters Investments Limited Porous inorganic/organic hybrid monolith materials for chromatographic separations and process for their preparation
GB2414993B (en) 2002-10-30 2007-07-11 Waters Investments Ltd Porous inorganic/organic homogenous copolymeric hybrid materials for chromatographic separations and process for the preparation thereof
WO2004071615A2 (en) 2003-02-07 2004-08-26 Waters Investments Limited Polymeric solid supports for chromatography nanocolumns
JP5459933B2 (ja) 2003-05-28 2014-04-02 ウオーターズ・テクノロジーズ・コーポレイシヨン 新規ナノコンポジットとモノリスカラムとしてのそれらの利用
US20040251188A1 (en) 2003-06-10 2004-12-16 Skinner Charles E. Immoblized alkylated amine functional macromolecules, alkylated ammonium salt functional macromolecules, and alkylated quaternary ammonium salt functional macromolecules, process for their preparation and methods for their use
US7074491B2 (en) 2003-11-04 2006-07-11 Dionex Corporation Polar silanes for binding to substrates and use of the bound substrates
US7125488B2 (en) 2004-02-12 2006-10-24 Varian, Inc. Polar-modified bonded phase materials for chromatographic separations
WO2005079427A2 (en) 2004-02-17 2005-09-01 Waters Investments Limited Porous hybrid monolith materials with organic groups removed from the surface
US20050242038A1 (en) 2004-04-30 2005-11-03 Wu Chen Novel stationary phases for use in high-performance liquid chromatography
WO2006023524A1 (en) * 2004-08-19 2006-03-02 Waters Investments Limited Device, method and apparatus for performing separations
US7402243B2 (en) * 2004-09-10 2008-07-22 Dionex Corporation Organosilanes and substrate bonded with same
US20070090052A1 (en) * 2005-10-20 2007-04-26 Broske Alan D Chromatographic stationary phase
US20070189944A1 (en) 2006-02-13 2007-08-16 Advanced Materials Technology, Inc. Porous microparticles with solid cores
WO2007109157A2 (en) * 2006-03-17 2007-09-27 Waters Investments Limited Solvent delivery system for liquid chromatography that maintains fluid integrity and pre-forms gradients
CN101152624B (zh) * 2006-10-01 2010-09-29 中国科学院大连化学物理研究所 一种醇羟基亲水色谱固定相及其制备方法
CN101657325B (zh) 2007-02-21 2013-11-20 沃特世科技公司 用于色谱分离的具有高有机质含量和增进的孔几何特征的多孔无机/有机混合颗粒
US7651762B2 (en) * 2007-03-13 2010-01-26 Varian, Inc. Methods and devices using a shrinkable support for porous monolithic materials
US7557232B2 (en) * 2007-05-25 2009-07-07 Dionex Corporation Compositions useful as chromatography stationary phases
CN101249426B (zh) * 2007-11-26 2011-04-06 福州大学 一种反相阴离子交换电色谱整体柱的原料配方及制备方法
US9248383B2 (en) * 2008-04-08 2016-02-02 Waters Technologies Corporation Composite materials containing nanoparticles and their use in chromatography
DE102008032687B4 (de) 2008-07-02 2021-05-06 Hansgrohe Se Befestigungsanordnung für wasserdurchflossene Sanitärbauteile
US20100061367A1 (en) 2008-09-11 2010-03-11 Pradeep Sindhu Methods and apparatus related to lossless operation within a data center
EP2365997B1 (en) 2008-11-26 2019-03-20 University College Cork - National University of Ireland, Cork A process for preparing silica microparticles
EP3964287A1 (en) * 2009-06-01 2022-03-09 Waters Technologies Corporation Hybrid material for chromatographic separations
IN2012DN00363A (xx) 2009-08-04 2015-08-21 Waters Technologies Corp
GB2473814B (en) * 2009-09-16 2014-06-11 Spheritech Ltd Hollow particulate support
EP2488544B1 (en) * 2009-10-15 2015-03-18 Monash University Affinity ligands and methods for protein purification
CN109078626A (zh) * 2009-12-15 2018-12-25 沃特世科技公司 实施体积排阻色谱的设备和方法
WO2012018598A1 (en) 2010-07-26 2012-02-09 Waters Technologies Corporation Superficially porous materials comprising a substantially nonporous core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations
CN103201008A (zh) 2010-08-06 2013-07-10 莫利康普矿物有限责任公司 高表面积稀土的附聚
WO2013173494A1 (en) * 2012-05-15 2013-11-21 Waters Technologies Corporation Chromatographic materials

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US20180345248A1 (en) 2018-12-06
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US11059026B2 (en) 2021-07-13
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