|
US9506119B2
(en)
|
2008-11-07 |
2016-11-29 |
Adaptive Biotechnologies Corp. |
Method of sequence determination using sequence tags
|
|
US8748103B2
(en)
|
2008-11-07 |
2014-06-10 |
Sequenta, Inc. |
Monitoring health and disease status using clonotype profiles
|
|
US9528160B2
(en)
|
2008-11-07 |
2016-12-27 |
Adaptive Biotechnolgies Corp. |
Rare clonotypes and uses thereof
|
|
US8236503B2
(en)
|
2008-11-07 |
2012-08-07 |
Sequenta, Inc. |
Methods of monitoring conditions by sequence analysis
|
|
US8628927B2
(en)
|
2008-11-07 |
2014-01-14 |
Sequenta, Inc. |
Monitoring health and disease status using clonotype profiles
|
|
US9365901B2
(en)
|
2008-11-07 |
2016-06-14 |
Adaptive Biotechnologies Corp. |
Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia
|
|
US8685898B2
(en)
|
2009-01-15 |
2014-04-01 |
Imdaptive, Inc. |
Adaptive immunity profiling and methods for generation of monoclonal antibodies
|
|
CA2765949C
(en)
|
2009-06-25 |
2016-03-29 |
Fred Hutchinson Cancer Research Center |
Method of measuring adaptive immunity
|
|
US8835358B2
(en)
|
2009-12-15 |
2014-09-16 |
Cellular Research, Inc. |
Digital counting of individual molecules by stochastic attachment of diverse labels
|
|
EP3578205A1
(en)
|
2010-08-06 |
2019-12-11 |
ModernaTX, Inc. |
A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof
|
|
HUE069586T2
(hu)
|
2010-10-01 |
2025-03-28 |
Modernatx Inc |
Módosított nukleozidok, nukleotidok és nukleinsavak, valamint ezek felhasználása
|
|
JP2014511687A
(ja)
|
2011-03-31 |
2014-05-19 |
モデルナ セラピューティクス インコーポレイテッド |
工学操作された核酸の送達および製剤
|
|
HRP20230443T1
(hr)
|
2011-05-24 |
2023-09-15 |
BioNTech SE |
Individualizirana cjepiva protiv raka
|
|
US10385475B2
(en)
|
2011-09-12 |
2019-08-20 |
Adaptive Biotechnologies Corp. |
Random array sequencing of low-complexity libraries
|
|
WO2013059725A1
(en)
|
2011-10-21 |
2013-04-25 |
Adaptive Biotechnologies Corporation |
Quantification of adaptive immune cell genomes in a complex mixture of cells
|
|
EP3388535B1
(en)
|
2011-12-09 |
2021-03-24 |
Adaptive Biotechnologies Corporation |
Diagnosis of lymphoid malignancies and minimal residual disease detection
|
|
US9499865B2
(en)
|
2011-12-13 |
2016-11-22 |
Adaptive Biotechnologies Corp. |
Detection and measurement of tissue-infiltrating lymphocytes
|
|
HRP20220717T1
(hr)
|
2011-12-16 |
2022-07-22 |
Modernatx, Inc. |
Modificirani pripravci mrna
|
|
ES2663234T3
(es)
|
2012-02-27 |
2018-04-11 |
Cellular Research, Inc |
Composiciones y kits para recuento molecular
|
|
US10077478B2
(en)
|
2012-03-05 |
2018-09-18 |
Adaptive Biotechnologies Corp. |
Determining paired immune receptor chains from frequency matched subunits
|
|
US9572897B2
(en)
|
2012-04-02 |
2017-02-21 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
|
US10501512B2
(en)
|
2012-04-02 |
2019-12-10 |
Modernatx, Inc. |
Modified polynucleotides
|
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
|
JP6189415B2
(ja)
|
2012-04-02 |
2017-08-30 |
モデルナティエックス インコーポレイテッドＭｏｄｅｒｎａＴＸ，Ｉｎｃ． |
細胞質および細胞骨格タンパク質の産生のための修飾ポリヌクレオチド
|
|
MX354329B
(es)
|
2012-05-08 |
2018-02-27 |
Adaptive Biotechnologies Corp |
Composiciones y metodos para medir y calibrar el error de amplificacion en reacciones de pcr multiple.
|
|
AU2013289939B2
(en)
*
|
2012-07-12 |
2018-08-09 |
Persimmune, Inc. |
Personalized cancer vaccines and adoptive immune cell therapies
|
|
WO2014028429A2
(en)
|
2012-08-14 |
2014-02-20 |
Moderna Therapeutics, Inc. |
Enzymes and polymerases for the synthesis of rna
|
|
ES2737757T3
(es)
|
2012-09-28 |
2020-01-15 |
Univ Connecticut |
Identificación de epítopos protectores contra tumores para el tratamiento de cánceres
|
|
ES2749118T3
(es)
|
2012-10-01 |
2020-03-19 |
Adaptive Biotechnologies Corp |
Evaluación de la inmunocompetencia por la diversidad de los receptores de inmunidad adaptativa y caracterización de la clonalidad
|
|
WO2015160439A2
(en)
|
2014-04-17 |
2015-10-22 |
Adaptive Biotechnologies Corporation |
Quantification of adaptive immune cell genomes in a complex mixture of cells
|
|
EP2922554B1
(en)
|
2012-11-26 |
2022-02-23 |
ModernaTX, Inc. |
Terminally modified rna
|
|
AU2013351542B2
(en)
*
|
2012-11-28 |
2018-08-09 |
BioNTech SE |
Individualized vaccines for cancer
|
|
WO2014093186A1
(en)
*
|
2012-12-12 |
2014-06-19 |
Garvin Alex M |
Non-invasive detection of colorectal neoplasia using circular consensus sequencing
|
|
US9128861B2
(en)
|
2013-01-17 |
2015-09-08 |
Personalis, Inc. |
Methods and systems for genetic analysis
|
|
US20160024181A1
(en)
|
2013-03-13 |
2016-01-28 |
Moderna Therapeutics, Inc. |
Long-lived polynucleotide molecules
|
|
EP2971010B1
(en)
|
2013-03-14 |
2020-06-10 |
ModernaTX, Inc. |
Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions
|
|
SG10201707394PA
(en)
*
|
2013-03-15 |
2017-10-30 |
Adaptive Biotechnologies Corp |
Uniquely tagged rearranged adaptive immune receptor genes in a complex gene set
|
|
KR102858313B1
(ko)
*
|
2013-04-07 |
2025-09-10 |
더 브로드 인스티튜트, 인코퍼레이티드 |
개인맞춤화 신생물 백신을 위한 조성물 및 방법
|
|
WO2014180490A1
(en)
*
|
2013-05-10 |
2014-11-13 |
Biontech Ag |
Predicting immunogenicity of t cell epitopes
|
|
US9708657B2
(en)
|
2013-07-01 |
2017-07-18 |
Adaptive Biotechnologies Corp. |
Method for generating clonotype profiles using sequence tags
|
|
US20160186260A1
(en)
*
|
2013-07-26 |
2016-06-30 |
Sequenta, Llc |
Cancer vaccination with antigen evolution
|
|
EP3480321B8
(en)
|
2013-08-28 |
2021-03-10 |
Becton, Dickinson and Company |
Massively parallel single cell analysis
|
|
WO2015031689A1
(en)
|
2013-08-30 |
2015-03-05 |
Personalis, Inc. |
Methods and systems for genomic analysis
|
|
EP3052106A4
(en)
|
2013-09-30 |
2017-07-19 |
ModernaTX, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
|
WO2015051275A1
(en)
|
2013-10-03 |
2015-04-09 |
Personalis, Inc. |
Methods for analyzing genotypes
|
|
CN105745528A
(zh)
|
2013-10-07 |
2016-07-06 |
赛卢拉研究公司 |
用于以数字方式对阵列上的特征进行计数的方法和系统
|
|
US10801070B2
(en)
|
2013-11-25 |
2020-10-13 |
The Broad Institute, Inc. |
Compositions and methods for diagnosing, evaluating and treating cancer
|
|
ES2693217T3
(es)
*
|
2013-12-02 |
2018-12-10 |
Personal Genome Diagnostics Inc. |
Método para evaluar variantes minoritarias en una muestra
|
|
WO2015085147A1
(en)
|
2013-12-05 |
2015-06-11 |
The Broad Institute Inc. |
Polymorphic gene typing and somatic change detection using sequencing data
|
|
KR102429859B1
(ko)
*
|
2013-12-06 |
2022-08-04 |
더 브로드 인스티튜트, 인코퍼레이티드 |
신생물 백신을 위한 제형
|
|
KR20230076867A
(ko)
*
|
2013-12-20 |
2023-05-31 |
더 브로드 인스티튜트, 인코퍼레이티드 |
신생항원 백신과의 병용 요법
|
|
WO2015134787A2
(en)
|
2014-03-05 |
2015-09-11 |
Adaptive Biotechnologies Corporation |
Methods using randomer-containing synthetic molecules
|
|
US10066265B2
(en)
|
2014-04-01 |
2018-09-04 |
Adaptive Biotechnologies Corp. |
Determining antigen-specific t-cells
|
|
HUE069802T2
(hu)
|
2014-04-23 |
2025-04-28 |
Modernatx Inc |
Nukleinsav vakcinák
|
|
US10017759B2
(en)
*
|
2014-06-26 |
2018-07-10 |
Illumina, Inc. |
Library preparation of tagged nucleic acid
|
|
US11338026B2
(en)
|
2014-09-10 |
2022-05-24 |
The University Of Connecticut |
Identification of immunologically protective neo-epitopes for the treatment of cancers
|
|
JP7044551B2
(ja)
|
2014-09-10 |
2022-03-30 |
ジェネンテック， インコーポレイテッド |
免疫原性変異体ペプチドスクリーニングプラットフォーム
|
|
WO2016053339A1
(en)
|
2014-10-02 |
2016-04-07 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods of isolating t cells having antigenic specificity for a cancer-specific mutation
|
|
ES2784343T3
(es)
|
2014-10-29 |
2020-09-24 |
Adaptive Biotechnologies Corp |
Detección simultánea altamente multiplexada de ácidos nucleicos que codifican heterodímeros de receptores inmunes adaptativos emparejados de muchas muestras
|
|
WO2016070131A1
(en)
|
2014-10-30 |
2016-05-06 |
Personalis, Inc. |
Methods for using mosaicism in nucleic acids sampled distal to their origin
|
|
US10246701B2
(en)
|
2014-11-14 |
2019-04-02 |
Adaptive Biotechnologies Corp. |
Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture
|
|
AU2015353581A1
(en)
|
2014-11-25 |
2017-06-15 |
Adaptive Biotechnologies Corporation |
Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing
|
|
WO2016100977A1
(en)
|
2014-12-19 |
2016-06-23 |
The Broad Institute Inc. |
Methods for profiling the t-cel- receptor repertoire
|
|
US10975442B2
(en)
|
2014-12-19 |
2021-04-13 |
Massachusetts Institute Of Technology |
Molecular biomarkers for cancer immunotherapy
|
|
WO2016128060A1
(en)
*
|
2015-02-12 |
2016-08-18 |
Biontech Ag |
Predicting t cell epitopes useful for vaccination
|
|
US10697010B2
(en)
*
|
2015-02-19 |
2020-06-30 |
Becton, Dickinson And Company |
High-throughput single-cell analysis combining proteomic and genomic information
|
|
US11047008B2
(en)
|
2015-02-24 |
2021-06-29 |
Adaptive Biotechnologies Corporation |
Methods for diagnosing infectious disease and determining HLA status using immune repertoire sequencing
|
|
MX2017010944A
(es)
|
2015-02-26 |
2018-07-06 |
Sio2 Medical Products Inc |
Recipiente de polimero de cicloolefina con un revestimiento resistente a arañazos y antiestatico.
|
|
ES2836802T3
(es)
|
2015-02-27 |
2021-06-28 |
Becton Dickinson Co |
Códigos de barras moleculares espacialmente direccionables
|
|
EP4180535A1
(en)
|
2015-03-30 |
2023-05-17 |
Becton, Dickinson and Company |
Methods and compositions for combinatorial barcoding
|
|
EP3277294B1
(en)
|
2015-04-01 |
2024-05-15 |
Adaptive Biotechnologies Corp. |
Method of identifying human compatible t cell receptors specific for an antigenic target
|
|
CN107580632B
(zh)
|
2015-04-23 |
2021-12-28 |
贝克顿迪金森公司 |
用于全转录组扩增的方法和组合物
|
|
RU2770447C2
(ru)
*
|
2015-04-27 |
2022-04-18 |
Кэнсэр Ресерч Текнолоджи Лимитед |
Способ лечения рака
|
|
WO2016180467A1
(en)
|
2015-05-11 |
2016-11-17 |
Biontech Cell & Gene Therapies Gmbh |
Enhancing the effect of car-engineered t cells by means of nucleic acid vaccination
|
|
SG10201912485PA
(en)
*
|
2015-05-13 |
2020-02-27 |
Agenus Inc |
Vaccines for treatment and prevention of cancer
|
|
WO2016187508A2
(en)
|
2015-05-20 |
2016-11-24 |
The Broad Institute Inc. |
Shared neoantigens
|
|
US11124823B2
(en)
|
2015-06-01 |
2021-09-21 |
Becton, Dickinson And Company |
Methods for RNA quantification
|
|
TW202241500A
(zh)
*
|
2015-06-09 |
2022-11-01 |
美商博德研究所有限公司 |
用於贅瘤疫苗之調配物及其製備方法
|
|
EP3328394A4
(en)
*
|
2015-07-30 |
2019-03-13 |
ModernaTX, Inc. |
CONCATEMEE peptide epitope RNAs
|
|
GB201516047D0
(en)
|
2015-09-10 |
2015-10-28 |
Cancer Rec Tech Ltd |
Method
|
|
WO2017044574A1
(en)
|
2015-09-11 |
2017-03-16 |
Cellular Research, Inc. |
Methods and compositions for nucleic acid library normalization
|
|
JP6990176B2
(ja)
|
2015-10-05 |
2022-02-03 |
モデルナティエックス インコーポレイテッド |
メッセンジャーリボ核酸薬物の治療投与のための方法
|
|
WO2017059902A1
(en)
*
|
2015-10-07 |
2017-04-13 |
Biontech Rna Pharmaceuticals Gmbh |
3' utr sequences for stabilization of rna
|
|
US11623001B2
(en)
|
2015-10-12 |
2023-04-11 |
Nantomics, Llc |
Compositions and methods for viral cancer neoepitopes
|
|
CN108604257B
(zh)
*
|
2015-10-12 |
2022-12-13 |
南托米克斯有限责任公司 |
产生特异性免疫治疗组合物及其相关核酸构建体的方法
|
|
CA3003090A1
(en)
*
|
2015-10-22 |
2017-04-27 |
Modernatx, Inc. |
Cancer vaccines
|
|
TWI765875B
(zh)
|
2015-12-16 |
2022-06-01 |
美商磨石生物公司 |
新抗原辨識、製造及用途
|
|
CN105349533A
(zh)
*
|
2015-12-21 |
2016-02-24 |
生工生物工程（上海）股份有限公司 |
构建链特异性转录组文库的方法
|
|
CA3008437A1
(en)
*
|
2016-01-08 |
2017-07-13 |
Vaccibody As |
Therapeutic anticancer neoepitope vaccine
|
|
US20190015491A1
(en)
*
|
2016-01-08 |
2019-01-17 |
Vaccibody As |
Neoepitope rna cancer vaccine
|
|
EP3475434A4
(en)
|
2016-03-24 |
2020-07-29 |
Nantcell, Inc. |
SEQUENCES AND SEQUENCES ARRANGEMENTS FOR PRESENTATION OF NEO-EPITOPIA
|
|
PT3436048T
(pt)
|
2016-03-31 |
2025-08-06 |
Biontech Us Inc |
Neoantigénios e métodos da sua utilização
|
|
WO2017184590A1
(en)
|
2016-04-18 |
2017-10-26 |
The Broad Institute Inc. |
Improved hla epitope prediction
|
|
EP3445392A1
(en)
*
|
2016-04-22 |
2019-02-27 |
CureVac AG |
Rna encoding a tumor antigen
|
|
WO2017192387A1
(en)
|
2016-05-02 |
2017-11-09 |
Cellular Research, Inc. |
Accurate molecular barcoding
|
|
AU2017260610B2
(en)
|
2016-05-04 |
2022-10-27 |
Immunovaccine Technologies Inc. |
Vaccine compositions comprising an amphipathic compound, a neoantigen and a hydrophobic carrier, and methods of use thereof
|
|
WO2017194170A1
(en)
|
2016-05-13 |
2017-11-16 |
Biontech Rna Pharmaceuticals Gmbh |
Methods for predicting the usefulness of proteins or protein fragments for immunotherapy
|
|
US10301677B2
(en)
|
2016-05-25 |
2019-05-28 |
Cellular Research, Inc. |
Normalization of nucleic acid libraries
|
|
US11397882B2
(en)
|
2016-05-26 |
2022-07-26 |
Becton, Dickinson And Company |
Molecular label counting adjustment methods
|
|
MX2018014602A
(es)
*
|
2016-05-27 |
2019-06-10 |
Etubics Corp |
Composiciones de vacunas neoepitopos y metodos de uso de las mismas.
|
|
US11299783B2
(en)
|
2016-05-27 |
2022-04-12 |
Personalis, Inc. |
Methods and systems for genetic analysis
|
|
US10640763B2
(en)
|
2016-05-31 |
2020-05-05 |
Cellular Research, Inc. |
Molecular indexing of internal sequences
|
|
US10202641B2
(en)
|
2016-05-31 |
2019-02-12 |
Cellular Research, Inc. |
Error correction in amplification of samples
|
|
KR20190027834A
(ko)
*
|
2016-07-13 |
2019-03-15 |
백심 아게 |
암 면역요법용 dna 백신을 제조하기 위한 방법
|
|
WO2018015433A2
(en)
*
|
2016-07-20 |
2018-01-25 |
Biontech Rna Pharmaceuticals Gmbh |
Selecting neoepitopes as disease-specific targets for therapy with enhanced efficacy
|
|
US10428325B1
(en)
|
2016-09-21 |
2019-10-01 |
Adaptive Biotechnologies Corporation |
Identification of antigen-specific B cell receptors
|
|
EP3516400B1
(en)
|
2016-09-26 |
2023-08-16 |
Becton, Dickinson and Company |
Measurement of protein expression using reagents with barcoded oligonucleotide sequences
|
|
EP4628595A3
(en)
|
2016-11-08 |
2025-11-05 |
Becton, Dickinson and Company |
Methods for cell label classification
|
|
CN109952612B
(zh)
|
2016-11-08 |
2023-12-01 |
贝克顿迪金森公司 |
用于表达谱分类的方法
|
|
US20190321481A1
(en)
|
2016-11-11 |
2019-10-24 |
Nantbio, Inc. |
Immunomodulatory compositions, processes for making the same, and methods for inhibiting cytokine storms
|
|
CN108090325B
(zh)
*
|
2016-11-23 |
2022-01-25 |
中国科学院昆明动物研究所 |
一种应用β-稳定性分析单细胞测序数据的方法
|
|
ES2961580T3
(es)
|
2017-01-13 |
2024-03-12 |
Cellular Res Inc |
Revestimiento hidrófilo de canales de fluidos
|
|
US20190369096A1
(en)
*
|
2017-01-13 |
2019-12-05 |
Nantbio, Inc. |
Validation of neoepitope-based treatment
|
|
CA3050109A1
(en)
*
|
2017-01-18 |
2018-07-26 |
Ichan School Of Medicine At Mount Sinai |
Neoantigens and uses thereof for treating cancer
|
|
EP3574116A1
(en)
|
2017-01-24 |
2019-12-04 |
The Broad Institute, Inc. |
Compositions and methods for detecting a mutant variant of a polynucleotide
|
|
MX2019009070A
(es)
*
|
2017-02-01 |
2019-10-30 |
Modernatx Inc |
Composiciones de arnm terapeuticas inmunomoduladoras que codifican peptidos de mutacion de oncogenes de activacion.
|
|
EP3576751A4
(en)
*
|
2017-02-01 |
2021-08-04 |
ModernaTX, Inc. |
RNA ANTI-CANCER VACCINES
|
|
US11319583B2
(en)
|
2017-02-01 |
2022-05-03 |
Becton, Dickinson And Company |
Selective amplification using blocking oligonucleotides
|
|
EP3580561B1
(en)
*
|
2017-02-12 |
2023-11-01 |
BioNTech US Inc. |
Hla-based methods and compositions and uses thereof
|
|
JP7249287B2
(ja)
|
2017-03-31 |
2023-03-30 |
ザ・ボード・オブ・トラスティーズ・オブ・ザ・リーランド・スタンフォード・ジュニア・ユニバーシティ |
Ｔ細胞受容体シグナル伝達を阻害または調節することによって、ｔ細胞枯渇を処置する方法
|
|
US12303561B2
(en)
|
2017-04-03 |
2025-05-20 |
Biontech Us Inc. |
Protein antigens and uses thereof
|
|
US11905525B2
(en)
|
2017-04-05 |
2024-02-20 |
Modernatx, Inc. |
Reduction of elimination of immune responses to non-intravenous, e.g., subcutaneously administered therapeutic proteins
|
|
IL270132B2
(en)
|
2017-04-24 |
2024-12-01 |
Nantcell Inc |
Neoepitope vectors and methods for them
|
|
WO2018208856A1
(en)
|
2017-05-08 |
2018-11-15 |
Gritstone Oncology, Inc. |
Alphavirus neoantigen vectors
|
|
EP3621629B1
(en)
|
2017-05-11 |
2025-12-24 |
Theralase Technologies Inc. |
Vaccine containing cancer cells inactivated by photodynamic treatment with metal-based coordination complexes, and immunotherapy method using same
|
|
US12072337B2
(en)
|
2017-05-30 |
2024-08-27 |
Nant Holdings Ip, Llc |
Circulating tumor cell enrichment using neoepitopes
|
|
CN110719959B
(zh)
|
2017-06-05 |
2021-08-06 |
贝克顿迪金森公司 |
针对单细胞的样品索引
|
|
WO2018224166A1
(en)
|
2017-06-09 |
2018-12-13 |
Biontech Rna Pharmaceuticals Gmbh |
Methods for predicting the usefulness of disease specific amino acid modifications for immunotherapy
|
|
JP7334124B2
(ja)
|
2017-06-21 |
2023-08-28 |
トランジェーヌ |
個別化ワクチン
|
|
WO2019005764A1
(en)
|
2017-06-27 |
2019-01-03 |
Institute For Cancer Research D/B/A The Research Institute Of Fox Chase Cancer Center |
MHC-I GENOTYPE LIMITING THE ONCOGEN MUTATIONAL LANDSCAPE
|
|
MX2020000414A
(es)
*
|
2017-07-12 |
2020-09-28 |
Nouscom Ag |
Composicion de vacuna de neoantigeno para el tratamiento del cancer.
|
|
US10636512B2
(en)
|
2017-07-14 |
2020-04-28 |
Cofactor Genomics, Inc. |
Immuno-oncology applications using next generation sequencing
|
|
US12504380B2
(en)
|
2017-09-25 |
2025-12-23 |
University Of Florida Research Foundation, Incorporated |
Immunoassays for detection of ran proteins
|
|
WO2019075112A1
(en)
|
2017-10-10 |
2019-04-18 |
Gritstone Oncology, Inc. |
IDENTIFICATION OF NEO-ANTIGENS USING HOT POINTS
|
|
AU2018373154B2
(en)
|
2017-11-22 |
2025-08-07 |
Seattle Project Corp. |
Reducing junction epitope presentation for neoantigens
|
|
US20200354730A1
(en)
*
|
2017-11-27 |
2020-11-12 |
Nantcell, Inc. |
Improved Yeast Polytope Vaccine Compositions And Methods
|
|
US11254980B1
(en)
|
2017-11-29 |
2022-02-22 |
Adaptive Biotechnologies Corporation |
Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements
|
|
WO2019105485A1
(zh)
*
|
2017-12-01 |
2019-06-06 |
上海桀蒙生物技术有限公司 |
个性化癌症疫苗的制备方法
|
|
WO2019126186A1
(en)
|
2017-12-18 |
2019-06-27 |
Neon Therapeutics, Inc. |
Neoantigens and uses thereof
|
|
CA3083792A1
(en)
*
|
2017-12-18 |
2019-06-27 |
Personal Genome Diagnostics Inc. |
Machine learning system and method for somatic mutation discovery
|
|
CN111492068B
(zh)
|
2017-12-19 |
2025-03-21 |
贝克顿迪金森公司 |
与寡核苷酸相关联的颗粒
|
|
CA3087537A1
(en)
|
2018-01-04 |
2019-07-11 |
Jan-willem THEUNISSEN |
Anti-tissue factor antibodies, antibody-drug conjugates, and related methods
|
|
JP7437310B2
(ja)
*
|
2018-03-14 |
2024-02-22 |
コーニンクレッカ フィリップス エヌ ヴェ |
Ｒｎａシーケンシングデータの転写発現レベルを解釈するために局所的なユニークな特徴を使用するシステム及び方法
|
|
US12462935B2
(en)
*
|
2018-03-30 |
2025-11-04 |
Nucleix Ltd. |
Deep learning-based methods, devices, and systems for prenatal testing
|
|
WO2019210055A2
(en)
|
2018-04-26 |
2019-10-31 |
Agenus Inc. |
Heat shock protein-binding peptide compositions and methods of use thereof
|
|
WO2019213237A1
(en)
|
2018-05-03 |
2019-11-07 |
Becton, Dickinson And Company |
Molecular barcoding on opposite transcript ends
|
|
AU2019262048B2
(en)
|
2018-05-03 |
2025-09-04 |
Becton, Dickinson And Company |
High throughput multiomics sample analysis
|
|
IL259392A
(en)
|
2018-05-15 |
2018-08-01 |
Yeda Res & Dev |
Vaccination with cancer neoantigens
|
|
JP2021525549A
(ja)
*
|
2018-05-25 |
2021-09-27 |
ザ ウィスター インスティテュート |
腫瘍特異的ネオ抗原およびその使用方法
|
|
CN108897986B
(zh)
*
|
2018-05-29 |
2020-11-27 |
中南大学 |
一种基于蛋白质信息的基因组序列拼接方法
|
|
US11814750B2
(en)
|
2018-05-31 |
2023-11-14 |
Personalis, Inc. |
Compositions, methods and systems for processing or analyzing multi-species nucleic acid samples
|
|
US10801064B2
(en)
|
2018-05-31 |
2020-10-13 |
Personalis, Inc. |
Compositions, methods and systems for processing or analyzing multi-species nucleic acid samples
|
|
TW202015719A
(zh)
|
2018-06-19 |
2020-05-01 |
美商尼恩醫療公司 |
新抗原及其用途
|
|
KR20210038886A
(ko)
*
|
2018-06-27 |
2021-04-08 |
모더나티엑스, 인크. |
개인화된 암 백신 에피토프 선택
|
|
WO2020020444A1
(en)
*
|
2018-07-24 |
2020-01-30 |
Biontech Rna Pharmaceuticals Gmbh |
Individualized vaccines for cancer
|
|
CA3106562A1
(en)
|
2018-07-26 |
2020-01-30 |
Frame Pharmaceuticals B.V. |
Off-the-shelf cancer vaccines
|
|
SG11202101965QA
(en)
|
2018-09-27 |
2021-04-29 |
Vaccibody As |
Method for selecting neoepitopes
|
|
WO2020072380A1
(en)
|
2018-10-01 |
2020-04-09 |
Cellular Research, Inc. |
Determining 5' transcript sequences
|
|
WO2020072700A1
(en)
|
2018-10-02 |
2020-04-09 |
Dana-Farber Cancer Institute, Inc. |
Hla single allele lines
|
|
CN114681600A
(zh)
*
|
2018-10-19 |
2022-07-01 |
杭州纽安津生物科技有限公司 |
通用性多肽疫苗及其在制备治疗/预防胰腺癌药物中的应用
|
|
CA3118947A1
(en)
*
|
2018-11-07 |
2020-05-14 |
Modernatx, Inc. |
Rna cancer vaccines
|
|
EP3877520B1
(en)
|
2018-11-08 |
2025-03-19 |
Becton, Dickson And Company |
Whole transcriptome analysis of single cells using random priming
|
|
US20210379170A1
(en)
*
|
2018-11-15 |
2021-12-09 |
Nouscom Ag |
Selection of cancer mutations for generation of a personalized cancer vaccine
|
|
US11492660B2
(en)
|
2018-12-13 |
2022-11-08 |
Becton, Dickinson And Company |
Selective extension in single cell whole transcriptome analysis
|
|
WO2020131586A2
(en)
|
2018-12-17 |
2020-06-25 |
The Broad Institute, Inc. |
Methods for identifying neoantigens
|
|
MX2021007556A
(es)
|
2018-12-21 |
2021-09-10 |
Biontech Us Inc |
Método y sistemas de predicción de epítopos específicos de hla de clase ii y caracterización de células t cd4+.
|
|
GB201821205D0
(en)
*
|
2018-12-24 |
2019-02-06 |
Tcer Ab |
Immunotherapy
|
|
GB201821207D0
(en)
|
2018-12-24 |
2019-02-06 |
Tcer Ab |
Immunotherapy therapy
|
|
US20220093217A1
(en)
*
|
2019-01-08 |
2022-03-24 |
Caris Mpi, Inc. |
Genomic profiling similarity
|
|
TW202515617A
(zh)
*
|
2019-01-14 |
2025-04-16 |
美商建南德克公司 |
用於癌症療法之rna分子
|
|
US11371076B2
(en)
|
2019-01-16 |
2022-06-28 |
Becton, Dickinson And Company |
Polymerase chain reaction normalization through primer titration
|
|
US11661631B2
(en)
|
2019-01-23 |
2023-05-30 |
Becton, Dickinson And Company |
Oligonucleotides associated with antibodies
|
|
WO2020163589A1
(en)
|
2019-02-08 |
2020-08-13 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
|
EP3924506A1
(en)
|
2019-02-14 |
2021-12-22 |
Becton Dickinson and Company |
Hybrid targeted and whole transcriptome amplification
|
|
WO2020167240A1
(en)
*
|
2019-02-15 |
2020-08-20 |
Rjan Holdng Ab |
Autologous cancer tumour associated extrachromosomal circular dna for use as a therapeutic vaccine
|
|
CN113784725A
(zh)
*
|
2019-03-01 |
2021-12-10 |
弗洛制药公司 |
个性化癌症疫苗的设计、制造和用途
|
|
JP7722661B2
(ja)
|
2019-03-13 |
2025-08-13 |
東洋紡株式会社 |
核酸の生成および増幅
|
|
US11965208B2
(en)
|
2019-04-19 |
2024-04-23 |
Becton, Dickinson And Company |
Methods of associating phenotypical data and single cell sequencing data
|
|
CN112011833B
(zh)
*
|
2019-05-30 |
2024-04-26 |
上海桀蒙生物技术有限公司 |
筛选和分离肿瘤新生抗原的方法
|
|
KR20220016137A
(ko)
|
2019-05-30 |
2022-02-08 |
그릿스톤 바이오, 인코포레이티드 |
변형된 아데노바이러스
|
|
CN114051534B
(zh)
|
2019-07-22 |
2025-02-21 |
贝克顿迪金森公司 |
单细胞染色质免疫沉淀测序测定
|
|
CN110277135B
(zh)
*
|
2019-08-10 |
2021-06-01 |
杭州新范式生物医药科技有限公司 |
一种基于预期疗效选择个体化肿瘤新抗原的方法和系统
|
|
EP4031562A4
(en)
*
|
2019-09-20 |
2023-11-01 |
University of Florida Research Foundation, Incorporated |
DETECTION OF ANTIBODIES AGAINST RAN PROTEINS FROM SERUM AND TISSUE LYSATES
|
|
US12331131B2
(en)
*
|
2019-09-20 |
2025-06-17 |
Navi Bio-Therapeutics, Inc. |
Personalized cancer immunotherapy
|
|
US12394502B2
(en)
|
2019-10-02 |
2025-08-19 |
The General Hospital Corporation |
Method for predicting HLA-binding peptides using protein structural features
|
|
CN114945987A
(zh)
|
2019-11-05 |
2022-08-26 |
佩索纳里斯公司 |
从单一样品预估肿瘤纯度
|
|
US11773436B2
(en)
|
2019-11-08 |
2023-10-03 |
Becton, Dickinson And Company |
Using random priming to obtain full-length V(D)J information for immune repertoire sequencing
|
|
CN112795647B
(zh)
*
|
2019-11-14 |
2022-08-16 |
北京肿瘤医院(北京大学肿瘤医院) |
一种肿瘤标志物及其应用
|
|
AR120741A1
(es)
|
2019-12-13 |
2022-03-16 |
Genentech Inc |
Anticuerpos anti-ly6g6d y métodos de uso
|
|
US11649497B2
(en)
|
2020-01-13 |
2023-05-16 |
Becton, Dickinson And Company |
Methods and compositions for quantitation of proteins and RNA
|
|
US12188010B2
(en)
|
2020-01-29 |
2025-01-07 |
Becton, Dickinson And Company |
Barcoded wells for spatial mapping of single cells through sequencing
|
|
EP4111168A1
(en)
|
2020-02-25 |
2023-01-04 |
Becton Dickinson and Company |
Bi-specific probes to enable the use of single-cell samples as single color compensation control
|
|
EP4117717A1
(en)
|
2020-03-13 |
2023-01-18 |
Codiak BioSciences, Inc. |
Extracellular vesicles for treating neurological disorders
|
|
AU2021236763A1
(en)
|
2020-03-20 |
2022-10-06 |
Lonza Sales Ag |
Extracellular vesicles for therapy
|
|
US11920202B2
(en)
|
2020-04-09 |
2024-03-05 |
University Of Connecticut |
Unbiased identification of tumor rejection mediating neoepitopes
|
|
CN115605614A
(zh)
|
2020-05-14 |
2023-01-13 |
贝克顿迪金森公司（Us） |
用于免疫组库谱分析的引物
|
|
EP4158014A2
(en)
|
2020-05-26 |
2023-04-05 |
Dionis Therapeutics, Inc. |
Nucleic acid artificial mini-proteome libraries
|
|
EP4158055B1
(en)
|
2020-06-02 |
2024-03-27 |
Becton, Dickinson and Company |
Oligonucleotides and beads for 5 prime gene expression assay
|
|
US11932901B2
(en)
|
2020-07-13 |
2024-03-19 |
Becton, Dickinson And Company |
Target enrichment using nucleic acid probes for scRNAseq
|
|
US12391940B2
(en)
|
2020-07-31 |
2025-08-19 |
Becton, Dickinson And Company |
Single cell assay for transposase-accessible chromatin
|
|
WO2022032196A2
(en)
|
2020-08-06 |
2022-02-10 |
Gritstone Bio, Inc. |
Multiepitope vaccine cassettes
|
|
WO2022036146A1
(en)
|
2020-08-12 |
2022-02-17 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
|
US20230323431A1
(en)
*
|
2020-08-31 |
2023-10-12 |
World Biotech Regenerative Medical Group Limited |
Personalized Immunogenic Compositions and Methods for Producing and Using Same
|
|
US20240082389A1
(en)
|
2020-09-23 |
2024-03-14 |
Lonza Sales Ag |
Methods of producing extracellular vesicles
|
|
US11739443B2
(en)
|
2020-11-20 |
2023-08-29 |
Becton, Dickinson And Company |
Profiling of highly expressed and lowly expressed proteins
|
|
US11161892B1
(en)
|
2020-12-07 |
2021-11-02 |
Think Therapeutics, Inc. |
Method of compact peptide vaccines using residue optimization
|
|
CN116710115A
(zh)
|
2020-11-20 |
2023-09-05 |
思维疗法股份有限公司 |
用于优化的肽疫苗的组合物和方法
|
|
US11421015B2
(en)
|
2020-12-07 |
2022-08-23 |
Think Therapeutics, Inc. |
Method of compact peptide vaccines using residue optimization
|
|
US11058751B1
(en)
|
2020-11-20 |
2021-07-13 |
Think Therapeutics, Inc. |
Compositions for optimized RAS peptide vaccines
|
|
KR20230142704A
(ko)
|
2020-12-14 |
2023-10-11 |
바이오엔테크 유에스 인크. |
암 면역요법을 위한 조직 특이적 항원
|
|
CN116685850A
(zh)
|
2020-12-15 |
2023-09-01 |
贝克顿迪金森公司 |
单细胞分泌组分析
|
|
US11464842B1
(en)
|
2021-04-28 |
2022-10-11 |
Think Therapeutics, Inc. |
Compositions and method for optimized peptide vaccines using residue optimization
|
|
CA3227081A1
(en)
|
2021-08-24 |
2023-03-02 |
Irena RABE |
In vitro transcription technologies
|
|
US12297508B2
(en)
|
2021-10-05 |
2025-05-13 |
Personalis, Inc. |
Customized assays for personalized cancer monitoring
|
|
WO2023085232A1
(ja)
|
2021-11-10 |
2023-05-19 |
東洋紡株式会社 |
改良されたライブラリー調製方法
|
|
EP4426829A1
(en)
|
2021-11-01 |
2024-09-11 |
Dana-Farber Cancer Institute, Inc. |
Biologically selected nucleic acid artificial mini-proteome libraries
|
|
CN114181287B
(zh)
*
|
2021-12-10 |
2023-09-19 |
商丘美兰生物工程有限公司 |
一种dna病毒疫苗的制备方法
|
|
CN114350800B
(zh)
*
|
2021-12-29 |
2024-03-19 |
中南大学湘雅医院 |
Sphk1在制备pd-l1/pd-1单抗肿瘤免疫治疗药物中的应用
|
|
CN114410778B
(zh)
*
|
2021-12-29 |
2024-03-19 |
中南大学湘雅医院 |
Pf543在制备pd-l1/pd-1单抗肿瘤免疫治疗药物中的应用
|
|
KR20230130804A
(ko)
*
|
2022-03-04 |
2023-09-12 |
(주)큐리진 |
순환종양세포 검출을 위한 아데노바이러스 5/3 형
|
|
EP4253550A1
(en)
|
2022-04-01 |
2023-10-04 |
GenCC GmbH 6 Co. KG |
Method for the manufacture of a viral system, a vector system or any transport system for cancer-specific crispr complexes
|
|
WO2023209068A1
(en)
|
2022-04-28 |
2023-11-02 |
Carbocalyx Gmbh |
Personalized anticancer vaccine comprising glycoengineered tumour cells or tumour cell fragments
|
|
WO2024015892A1
(en)
|
2022-07-13 |
2024-01-18 |
The Broad Institute, Inc. |
Hla-ii immunopeptidome methods and systems for antigen discovery
|
|
WO2024063788A1
(en)
*
|
2022-09-23 |
2024-03-28 |
BioNTech SE |
Compositions for delivery of malaria antigens and related methods
|
|
CN120225219A
(zh)
*
|
2022-09-23 |
2025-06-27 |
生物技术欧洲股份公司 |
用于递送肝期抗原的组合物及相关方法
|
|
WO2024083345A1
(en)
|
2022-10-21 |
2024-04-25 |
BioNTech SE |
Methods and uses associated with liquid compositions
|
|
CN120584195A
(zh)
|
2023-01-26 |
2025-09-02 |
东洋纺株式会社 |
源自核糖体rna的逆转录的抑制
|
|
WO2024231973A1
(ja)
*
|
2023-05-08 |
2024-11-14 |
株式会社日立製作所 |
情報処理装置
|
|
WO2025024337A1
(en)
*
|
2023-07-24 |
2025-01-30 |
BioNTech SE |
Compositions for delivery of plasmodium antigens and related methods
|
|
WO2025064850A1
(en)
*
|
2023-09-22 |
2025-03-27 |
BioNTech SE |
Rna constructs with n-terminal degrons to enhance an immune response
|
|
WO2025097055A2
(en)
|
2023-11-02 |
2025-05-08 |
The Broad Institute, Inc. |
Compositions and methods of use of t cells in immunotherapy
|
|
WO2025146078A1
(en)
*
|
2024-01-04 |
2025-07-10 |
Everest Medicines (China) Co., Ltd. |
Cancer vaccines and uses thereof
|
|
WO2025191449A1
(en)
|
2024-03-11 |
2025-09-18 |
Instadeep Ltd |
Systems and methods for machine learning-based genome annotation
|
|
WO2025202937A1
(en)
|
2024-03-26 |
2025-10-02 |
BioNTech SE |
Cancer vaccines
|
|
WO2025207807A1
(en)
*
|
2024-03-27 |
2025-10-02 |
The University Of Florida Research Foundation, Inc. |
Ctc rna-loaded nanoparticles and use thereof for the treatment of cancer
|
|
WO2025257735A1
(en)
|
2024-06-10 |
2025-12-18 |
BioNTech SE |
Systems and methods for machine learning model-based prediction of immune response
|
|
CN119049567B
(zh)
*
|
2024-08-08 |
2025-07-22 |
笙源生命科技(安吉)有限公司 |
一种基于单细胞测序区分嵌合体动物模型中异种杂交样本遗传物质和细胞物种来源的方法
|