JP2019512020A5 - - Google Patents
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- JP2019512020A5 JP2019512020A5 JP2018561191A JP2018561191A JP2019512020A5 JP 2019512020 A5 JP2019512020 A5 JP 2019512020A5 JP 2018561191 A JP2018561191 A JP 2018561191A JP 2018561191 A JP2018561191 A JP 2018561191A JP 2019512020 A5 JP2019512020 A5 JP 2019512020A5
- Authority
- JP
- Japan
- Prior art keywords
- vaccine
- days
- use according
- inhibitor
- administering
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 229960005486 vaccine Drugs 0.000 claims 29
- 239000012270 PD-1 inhibitor Substances 0.000 claims 10
- 239000012668 PD-1-inhibitor Substances 0.000 claims 10
- 229940121655 pd-1 inhibitor Drugs 0.000 claims 10
- 206010028980 Neoplasm Diseases 0.000 claims 4
- 102100035703 Prostatic acid phosphatase Human genes 0.000 claims 4
- 108010043671 prostatic acid phosphatase Proteins 0.000 claims 4
- 210000001744 T-lymphocyte Anatomy 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 206010061818 Disease progression Diseases 0.000 claims 2
- 238000011260 co-administration Methods 0.000 claims 2
- 230000005750 disease progression Effects 0.000 claims 2
- 230000001747 exhibiting effect Effects 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 208000005443 Circulating Neoplastic Cells Diseases 0.000 claims 1
- 101001035654 Homo sapiens 28 kDa heat- and acid-stable phosphoprotein Proteins 0.000 claims 1
- 101000785915 Homo sapiens Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 Proteins 0.000 claims 1
- 101000735427 Homo sapiens Poly(A) RNA polymerase, mitochondrial Proteins 0.000 claims 1
- 101150073131 PAP gene Proteins 0.000 claims 1
- 108091007744 Programmed cell death receptors Proteins 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 230000006023 anti-tumor response Effects 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 229960003301 nivolumab Drugs 0.000 claims 1
- 229960002621 pembrolizumab Drugs 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022064122A JP2022088665A (ja) | 2016-02-12 | 2022-04-07 | がんの治療 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662294349P | 2016-02-12 | 2016-02-12 | |
| US62/294,349 | 2016-02-12 | ||
| US201662404252P | 2016-10-05 | 2016-10-05 | |
| US62/404,252 | 2016-10-05 | ||
| PCT/US2017/017445 WO2017139628A1 (en) | 2016-02-12 | 2017-02-10 | Cancer therapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022064122A Division JP2022088665A (ja) | 2016-02-12 | 2022-04-07 | がんの治療 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019512020A JP2019512020A (ja) | 2019-05-09 |
| JP2019512020A5 true JP2019512020A5 (enExample) | 2020-03-26 |
Family
ID=59088211
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018561191A Ceased JP2019512020A (ja) | 2016-02-12 | 2017-02-10 | がんの治療 |
| JP2022064122A Pending JP2022088665A (ja) | 2016-02-12 | 2022-04-07 | がんの治療 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022064122A Pending JP2022088665A (ja) | 2016-02-12 | 2022-04-07 | がんの治療 |
Country Status (8)
| Country | Link |
|---|---|
| US (5) | US11000578B2 (enExample) |
| EP (1) | EP3413927A4 (enExample) |
| JP (2) | JP2019512020A (enExample) |
| CN (1) | CN108883203A (enExample) |
| AU (1) | AU2017217940B2 (enExample) |
| CA (1) | CA3013930C (enExample) |
| HK (1) | HK1258319A1 (enExample) |
| WO (1) | WO2017139628A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018209270A1 (en) | 2017-05-11 | 2018-11-15 | Northwestern University | Adoptive cell therapy using spherical nucleic acids (snas) |
| AU2019327490A1 (en) * | 2018-08-30 | 2021-03-25 | Innovative Cellular Therapeutics Holdings, Ltd. | Chimeric antigen receptor cells for treating solid tumor |
| WO2020097209A1 (en) * | 2018-11-06 | 2020-05-14 | Wisconsin Alumni Research Foundation | Treating prostate cancer using a combination of a dna vaccine, pd-1 inhibitor and an ido inhibitor |
| CN109593135B (zh) * | 2018-12-29 | 2021-01-15 | 百奥赛图江苏基因生物技术有限公司 | 抗人pd-l1单克隆抗体及其应用 |
| AU2020218259A1 (en) * | 2019-02-08 | 2021-09-02 | Madison Vaccines Inc. | Cancer therapy |
| CN110632292A (zh) * | 2019-06-12 | 2019-12-31 | 江苏莱尔生物医药科技有限公司 | 一种检测pd-l1和cd8抗原的免疫荧光试剂盒及应用方法 |
| WO2021108331A1 (en) * | 2019-11-26 | 2021-06-03 | The Regents Of The University Of California | Combination therapy for head and neck cancer |
| CN111141906A (zh) * | 2020-01-06 | 2020-05-12 | 中南大学湘雅医院 | 一种小细胞肺癌患者外周血循环肿瘤细胞及pd-l1的检测试剂盒 |
| EP4175664A2 (en) * | 2020-07-06 | 2023-05-10 | Janssen Biotech, Inc. | Prostate neoantigens and their uses |
| WO2023118360A1 (en) | 2021-12-23 | 2023-06-29 | Universiteit Maastricht | Immunoprotective type implantable cell delivery device |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6943236B2 (en) | 1997-02-25 | 2005-09-13 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
| AU7994200A (en) * | 1999-10-04 | 2001-05-10 | Corixa Corporation | Compositions and methods for therapy and diagnosis of prostate cancer |
| US7179797B2 (en) | 2002-09-27 | 2007-02-20 | Wisconsin Alumni Research Foundation | Methods and compositions for treating prostate cancer using DNA vaccines |
| US20070232558A1 (en) | 2006-03-31 | 2007-10-04 | Mcneel Douglas G | Methods and compositions for treating prostate cancer using dna vaccines directed to cancer testis antigen |
| US7910565B2 (en) | 2006-09-01 | 2011-03-22 | Wisconsin Alumni Research Foundation | Prostate cancer vaccine |
| WO2008085562A2 (en) | 2006-09-20 | 2008-07-17 | The Johns Hopkins University | Combinatorieal therapy of cancer and infectious diseases with anti-b7-h1 antibodies |
| US9060961B2 (en) | 2006-11-09 | 2015-06-23 | University Of Washington | Molecules and methods for treatment and detection of cancer |
| WO2008103645A2 (en) | 2007-02-19 | 2008-08-28 | Wisconsin Alumni Research Foundation | Prostate cancer and melanoma antigens |
| WO2009052328A1 (en) | 2007-10-18 | 2009-04-23 | Bn Immunotherapeutics Inc. | Use of mva to treat prostate cancer |
| EP2419126B1 (en) | 2009-04-17 | 2018-01-10 | Globeimmune, Inc. | Combination immunotherapy compositions against cancer and methods |
| US20110301052A1 (en) | 2010-04-16 | 2011-12-08 | Mcneel Douglas G | Diagnostic evaluation of antibody responses to commonly recognized prostate cancer-associated antigens |
| US8603485B2 (en) | 2011-01-05 | 2013-12-10 | Wisconsin Alumni Research Foundation | Bystander immune suppression as a predictor for response to a vaccine |
| NZ701324A (en) * | 2012-05-04 | 2016-09-30 | Pfizer | Prostate-associated antigens and vaccine-based immunotherapy regimens |
| EP4070818A3 (en) | 2014-01-06 | 2023-01-11 | The Trustees of the University of Pennsylvania | Pd1 and pdl1 antibodies and vaccine combinations and use of same for immunotherapy |
| JOP20200094A1 (ar) * | 2014-01-24 | 2017-06-16 | Dana Farber Cancer Inst Inc | جزيئات جسم مضاد لـ pd-1 واستخداماتها |
| MX2017000857A (es) * | 2014-07-18 | 2017-10-11 | Advaxis Inc | Combinación de un antagonista de la proteina de muerte programada (pd-1) y una vacuna basada en listeria para tratar el cáncer de próstata. |
| JP2017535599A (ja) | 2014-11-07 | 2017-11-30 | ウィスコンシン アラムニ リサーチ ファンデーション | Ｂ細胞標的ｄｎａワクチン |
| WO2016094639A1 (en) | 2014-12-10 | 2016-06-16 | Wisconsin Alumni Research Foundation | Mini-intronic plasmid dna vaccines in combination with lag3 blockade |
| WO2017139755A1 (en) | 2016-02-12 | 2017-08-17 | Rekoske Brian T | Cancer therapy |
-
2017
- 2017-02-10 AU AU2017217940A patent/AU2017217940B2/en not_active Expired - Fee Related
- 2017-02-10 WO PCT/US2017/017445 patent/WO2017139628A1/en not_active Ceased
- 2017-02-10 CN CN201780018603.6A patent/CN108883203A/zh active Pending
- 2017-02-10 HK HK19100687.7A patent/HK1258319A1/zh unknown
- 2017-02-10 CA CA3013930A patent/CA3013930C/en active Active
- 2017-02-10 JP JP2018561191A patent/JP2019512020A/ja not_active Ceased
- 2017-02-10 US US15/430,012 patent/US11000578B2/en active Active
- 2017-02-10 EP EP17750860.3A patent/EP3413927A4/en not_active Withdrawn
- 2017-02-13 US US16/077,680 patent/US20190030150A1/en not_active Abandoned
-
2021
- 2021-05-06 US US17/313,335 patent/US11806391B2/en active Active
-
2022
- 2022-04-07 JP JP2022064122A patent/JP2022088665A/ja active Pending
-
2023
- 2023-10-23 US US18/492,311 patent/US20240115684A1/en not_active Abandoned
-
2024
- 2024-11-15 US US18/948,989 patent/US20250074987A1/en active Pending
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