JP2014517842A5 - - Google Patents
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- JP2014517842A5 JP2014517842A5 JP2014512101A JP2014512101A JP2014517842A5 JP 2014517842 A5 JP2014517842 A5 JP 2014517842A5 JP 2014512101 A JP2014512101 A JP 2014512101A JP 2014512101 A JP2014512101 A JP 2014512101A JP 2014517842 A5 JP2014517842 A5 JP 2014517842A5
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- Prior art keywords
- cancer
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- pharmaceutically acceptable
- acceptable salt
- formula
- Prior art date
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- AGGWFDNPHKLBBV-YUMQZZPRSA-N (2s)-2-[[(2s)-2-amino-3-methylbutanoyl]amino]-5-(carbamoylamino)pentanoic acid Chemical compound CC(C)[C@H](N)C(=O)N[C@H](C(O)=O)CCCNC(N)=O AGGWFDNPHKLBBV-YUMQZZPRSA-N 0.000 claims 1
- ALBODLTZUXKBGZ-JUUVMNCLSA-N (2s)-2-amino-3-phenylpropanoic acid;(2s)-2,6-diaminohexanoic acid Chemical compound NCCCC[C@H](N)C(O)=O.OC(=O)[C@@H](N)CC1=CC=CC=C1 ALBODLTZUXKBGZ-JUUVMNCLSA-N 0.000 claims 1
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161490117P | 2011-05-26 | 2011-05-26 | |
| US61/490,117 | 2011-05-26 | ||
| PCT/US2012/039312 WO2012162482A1 (en) | 2011-05-26 | 2012-05-24 | Immunoconjugates, compositions containing them, and methods of making and use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017017666A Division JP6359133B2 (ja) | 2011-05-26 | 2017-02-02 | 免疫コンジュゲート、それらを含有する組成物、ならびに製造方法および使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014517842A JP2014517842A (ja) | 2014-07-24 |
| JP2014517842A5 true JP2014517842A5 (OSRAM) | 2015-05-21 |
| JP6105566B2 JP6105566B2 (ja) | 2017-03-29 |
Family
ID=46172969
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014512101A Expired - Fee Related JP6105566B2 (ja) | 2011-05-26 | 2012-05-24 | 免疫コンジュゲート、それらを含有する組成物、ならびに製造方法および使用方法 |
| JP2017017666A Expired - Fee Related JP6359133B2 (ja) | 2011-05-26 | 2017-02-02 | 免疫コンジュゲート、それらを含有する組成物、ならびに製造方法および使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017017666A Expired - Fee Related JP6359133B2 (ja) | 2011-05-26 | 2017-02-02 | 免疫コンジュゲート、それらを含有する組成物、ならびに製造方法および使用方法 |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US8852599B2 (OSRAM) |
| EP (1) | EP2714092B1 (OSRAM) |
| JP (2) | JP6105566B2 (OSRAM) |
| KR (1) | KR102070464B1 (OSRAM) |
| CN (1) | CN103561772B (OSRAM) |
| AR (1) | AR086568A1 (OSRAM) |
| AU (1) | AU2012258750B2 (OSRAM) |
| BR (1) | BR112013029764A2 (OSRAM) |
| CA (1) | CA2837327C (OSRAM) |
| CL (1) | CL2013003393A1 (OSRAM) |
| CO (1) | CO6831975A2 (OSRAM) |
| EA (1) | EA024844B1 (OSRAM) |
| ES (1) | ES2814798T3 (OSRAM) |
| IL (1) | IL229477A (OSRAM) |
| MA (1) | MA35153B1 (OSRAM) |
| MX (1) | MX336806B (OSRAM) |
| PE (1) | PE20141480A1 (OSRAM) |
| PH (1) | PH12013502189A1 (OSRAM) |
| SG (1) | SG195011A1 (OSRAM) |
| TW (1) | TW201300401A (OSRAM) |
| UY (1) | UY34100A (OSRAM) |
| WO (1) | WO2012162482A1 (OSRAM) |
| ZA (2) | ZA201309669B (OSRAM) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5868593B2 (ja) * | 2007-07-17 | 2016-02-24 | メダレックス・リミテッド・ライアビリティ・カンパニーMedarex, L.L.C. | Glypican−3に対するモノクローナル抗体 |
| EP2794653B1 (en) | 2011-12-23 | 2019-03-13 | Pfizer Inc | Engineered antibody constant regions for site-specific conjugation and methods and uses therefor |
| AU2013364065B2 (en) | 2012-12-21 | 2018-10-04 | Altrubio Inc. | Hydrophilic self-immolative linkers and conjugates thereof |
| JP6574754B2 (ja) | 2013-03-19 | 2019-09-11 | ベイジン シェノゲン ファーマ グループ リミテッド | エストロゲン受容体関連疾患を処置するための抗体及び方法 |
| PL2991683T3 (pl) | 2013-05-02 | 2020-03-31 | Glykos Finland Oy | Koniugaty glikoproteiny lub glikanu z toksycznym ładunkiem |
| EP3033111B1 (en) | 2013-08-12 | 2019-03-13 | Genentech, Inc. | 1-(chloromethyl)-2,3-dihydro-1h-benzo[e]indole dimer antibody-drug conjugate compounds, and methods of use and treatment |
| BR112016013258A2 (pt) | 2013-12-16 | 2018-01-16 | Genentech Inc | composto conjugado anticorpo-droga, composição farmacêutica, método para tratar câncer e kit |
| HUE043427T2 (hu) * | 2014-01-27 | 2019-08-28 | Pfizer | Bifunkciós citotoxikus szerek |
| ES2898273T3 (es) | 2014-03-20 | 2022-03-04 | Bristol Myers Squibb Co | Moléculas con una estructura a base de fibronectina estabilizada |
| RU2708075C2 (ru) | 2014-04-30 | 2019-12-04 | Пфайзер Инк. | Конъюгаты анти-ртк7 антитело-лекарственное средство |
| CA2952876A1 (en) | 2014-06-20 | 2015-12-23 | Bioalliance C.V. | Anti-folate receptor alpha (fra) antibody-drug conjugates and methods of using thereof |
| JP2017523958A (ja) * | 2014-06-20 | 2017-08-24 | バイオアライアンス コマンディテール フェンノートシャップ | 抗cd22抗体−薬物コンジュゲート及びその使用方法 |
| AU2015282627B2 (en) | 2014-06-30 | 2020-04-02 | Glykos Finland Oy | Saccharide derivative of a toxic payload and antibody conjugates thereof |
| GB201412658D0 (en) | 2014-07-16 | 2014-08-27 | Ucb Biopharma Sprl | Molecules |
| LT3221363T (lt) | 2014-11-21 | 2020-08-10 | Bristol-Myers Squibb Company | Antikūnai prieš cd73 ir jų panaudojimas |
| EP3789399A1 (en) | 2014-11-21 | 2021-03-10 | Bristol-Myers Squibb Company | Antibodies comprising modified heavy constant regions |
| ES2822990T3 (es) | 2014-11-25 | 2021-05-05 | Bristol Myers Squibb Co | Novedosos polipéptidos de unión a PD-L1 para obtención de imágenes |
| US10676773B2 (en) | 2015-03-10 | 2020-06-09 | Bristol-Myers Squibb Company | Antibodies conjugatable by transglutaminase and conjugates made therefrom |
| WO2016151432A1 (en) | 2015-03-20 | 2016-09-29 | Pfizer Inc. | Bifunctional cytotoxic agents containing the cti pharmacophore |
| JP6797137B2 (ja) | 2015-05-29 | 2020-12-09 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | Ox40に対する抗体およびその使用 |
| PL3319597T3 (pl) | 2015-07-10 | 2021-10-11 | Byondis B.V. | Kompozycje zawierające koniugaty przeciwciało-duokarmycyna |
| GB201601075D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibodies molecules |
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