PL1851250T3 - Ludzkie przeciwciało monoklonalne przeciwko antygenowi błony komórkowej komórek prostaty (PSMA) - Google Patents
Ludzkie przeciwciało monoklonalne przeciwko antygenowi błony komórkowej komórek prostaty (PSMA)Info
- Publication number
- PL1851250T3 PL1851250T3 PL06735489T PL06735489T PL1851250T3 PL 1851250 T3 PL1851250 T3 PL 1851250T3 PL 06735489 T PL06735489 T PL 06735489T PL 06735489 T PL06735489 T PL 06735489T PL 1851250 T3 PL1851250 T3 PL 1851250T3
- Authority
- PL
- Poland
- Prior art keywords
- psma
- monoclonal antibody
- human monoclonal
- prostate specific
- specific membrane
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65412505P | 2005-02-18 | 2005-02-18 | |
| US72049905P | 2005-09-26 | 2005-09-26 | |
| US74841705P | 2005-12-08 | 2005-12-08 | |
| EP06735489A EP1851250B1 (en) | 2005-02-18 | 2006-02-17 | Human monoclonal antibody to prostate specific membrane antigen (psma) |
| PCT/US2006/005852 WO2006089230A2 (en) | 2005-02-18 | 2006-02-17 | Human monoclonal antibodies to prostate specific membrane antigen (psma) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1851250T3 true PL1851250T3 (pl) | 2012-10-31 |
Family
ID=36658707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL06735489T PL1851250T3 (pl) | 2005-02-18 | 2006-02-17 | Ludzkie przeciwciało monoklonalne przeciwko antygenowi błony komórkowej komórek prostaty (PSMA) |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20090297438A1 (pl) |
| EP (1) | EP1851250B1 (pl) |
| JP (1) | JP2008529556A (pl) |
| KR (1) | KR20070115967A (pl) |
| CN (1) | CN101124249B (pl) |
| AU (1) | AU2006214031A1 (pl) |
| BR (1) | BRPI0607757A2 (pl) |
| CA (1) | CA2598522A1 (pl) |
| CY (1) | CY1113089T1 (pl) |
| DK (1) | DK1851250T3 (pl) |
| ES (1) | ES2386366T3 (pl) |
| HR (1) | HRP20120709T1 (pl) |
| IL (1) | IL184733A (pl) |
| MX (1) | MX2007009878A (pl) |
| NO (1) | NO20073797L (pl) |
| NZ (1) | NZ556661A (pl) |
| PL (1) | PL1851250T3 (pl) |
| PT (1) | PT1851250E (pl) |
| WO (1) | WO2006089230A2 (pl) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050215472A1 (en) | 2001-10-23 | 2005-09-29 | Psma Development Company, Llc | PSMA formulations and uses thereof |
| ES2559002T3 (es) | 2001-10-23 | 2016-02-10 | Psma Development Company, L.L.C. | Anticuerpos contra PSMA |
| EP1726650A1 (en) * | 2005-05-27 | 2006-11-29 | Universitätsklinikum Freiburg | Monoclonal antibodies and single chain antibody fragments against cell-surface prostate specific membrane antigen |
| DE102008010363A1 (de) * | 2008-02-18 | 2009-08-20 | Lang, Florian, Prof. Dr.med. | Sgk1 als therapeutisches und diagnostisches Target für karzinomatöse Erkrankungen |
| CA2721169A1 (en) * | 2008-04-14 | 2009-10-22 | Proscan Rx Pharma Inc. | Prostate specific membrane antigen antibodies and antigen binding fragments |
| WO2010027513A2 (en) | 2008-09-08 | 2010-03-11 | Psma Development Company, Llc | Methods for killing psma-expressing, taxane-resistant cancer cells |
| AU2009299793B2 (en) | 2008-10-01 | 2016-03-10 | Amgen Research (Munich) Gmbh | Bispecific single chain antibodies with specificity for high molecular weight target antigens |
| EP3106468A1 (en) * | 2008-10-01 | 2016-12-21 | Amgen Research (Munich) GmbH | Cross-species-specific psmaxcd3 bispecific single chain antibody |
| CN101891818B (zh) * | 2009-01-16 | 2012-07-25 | 中国人民解放军第四军医大学 | 抗人前列腺特异性膜抗原胞外区单链抗体及其应用 |
| EP2419451A4 (en) * | 2009-04-14 | 2012-11-14 | Proscan Rx Pharma Inc | ANTIBODIES DIRECTED AGAINST THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN |
| US20120183847A1 (en) | 2009-05-19 | 2012-07-19 | Aic Blab | Composite current collector and methods therefor |
| US8394922B2 (en) | 2009-08-03 | 2013-03-12 | Medarex, Inc. | Antiproliferative compounds, conjugates thereof, methods therefor, and uses thereof |
| TWI629357B (zh) * | 2009-10-02 | 2018-07-11 | 安進研究(慕尼黑)有限責任公司 | 跨物種特異性的PSMAxCD3雙特異性單鏈抗體 |
| TWI653333B (zh) | 2010-04-01 | 2019-03-11 | 安進研究(慕尼黑)有限責任公司 | 跨物種專一性之PSMAxCD3雙專一性單鏈抗體 |
| US8956859B1 (en) | 2010-08-13 | 2015-02-17 | Aviex Technologies Llc | Compositions and methods for determining successful immunization by one or more vaccines |
| RU2632647C2 (ru) | 2011-04-22 | 2017-10-06 | Аптево Рисерч Энд Девелопмент Ллс | Белки, связывающие специфический мембранный антиген простаты, и соответствующие композиции и способы |
| US8852599B2 (en) | 2011-05-26 | 2014-10-07 | Bristol-Myers Squibb Company | Immunoconjugates, compositions for making them, and methods of making and use |
| US20140099257A1 (en) * | 2012-10-05 | 2014-04-10 | Cornell University | Androgen Suppression, Prostate-Specific Membrane Antigen and the Concept of Conditionally Enhanced Vulnerability |
| SI2956173T1 (sl) | 2013-02-14 | 2017-06-30 | Bristol-Myers Squibb Company | Spojine tubulizina, postopki pridobivanja in uporaba |
| MX368016B (es) | 2013-08-14 | 2019-09-13 | Univ Rice William M | Derivados de uncialamicina, métodos de sintesis y su uso como agentes antitumor. |
| US10077287B2 (en) | 2014-11-10 | 2018-09-18 | Bristol-Myers Squibb Company | Tubulysin analogs and methods of making and use |
| LT3221346T (lt) | 2014-11-21 | 2020-11-10 | Bristol-Myers Squibb Company | Antikūnai, apimantys modifikuotas sunkiosios grandinės pastoviąsias sritis |
| ES2747386T3 (es) | 2015-01-14 | 2020-03-10 | Bristol Myers Squibb Co | Dímeros de benzodiacepina unidos por heteroarileno, conjugados de los mismos y métodos de preparación y uso |
| TW201639891A (zh) * | 2015-03-10 | 2016-11-16 | 索倫多醫療公司 | 結合psma之抗體治療劑 |
| JOP20160154B1 (ar) * | 2015-07-31 | 2021-08-17 | Regeneron Pharma | أجسام ضادة مضاد لل psma، وجزيئات رابطة لمستضد ثنائي النوعية الذي يربط psma و cd3، واستخداماتها |
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| JP2019505575A (ja) | 2015-12-21 | 2019-02-28 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | 部位特異的な結合のための変異型抗体 |
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| CN105542008A (zh) * | 2016-02-03 | 2016-05-04 | 南昌大学 | 能特异结合前列腺特异性膜抗原的单域重链抗体 |
| CN105524171A (zh) * | 2016-02-03 | 2016-04-27 | 中国人民解放军第三军医大学第三附属医院 | 一种针对前列腺特异性膜抗原的纳米抗体 |
| CN105504061A (zh) * | 2016-02-03 | 2016-04-20 | 南昌大学 | 针对前列腺特异性膜抗原的纳米抗体 |
| AU2017250191A1 (en) | 2016-04-13 | 2018-11-08 | Orimabs Ltd. | Anti-PSMA antibodies and use thereof |
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| ES2902179T3 (es) | 2016-08-19 | 2022-03-25 | Bristol Myers Squibb Co | Compuestos de seco-ciclopropapirroloindol, conjugados de anticuerpo-fármaco de los mismos y métodos de elaboración y uso |
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| EP3565842A1 (en) | 2017-01-06 | 2019-11-13 | Crescendo Biologics Limited | Single domain antibodies to programmed cell death (pd-1) |
| IL322309A (en) | 2017-05-24 | 2025-09-01 | Novartis Ag | IL2 antibody grafted proteins and methods of use in cancer treatment |
| MX2019013132A (es) | 2017-05-25 | 2020-01-27 | Bristol Myers Squibb Co | Anticuerpos que comprenden regiones constantes pesadas modificadas. |
| GB201711068D0 (en) | 2017-07-10 | 2017-08-23 | Crescendo Biologics Ltd | Therapeutic molecules binding PSMA |
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| US10457681B2 (en) | 2017-08-16 | 2019-10-29 | Bristol_Myers Squibb Company | Toll-like receptor 7 (TLR7) agonists having a tricyclic moiety, conjugates thereof, and methods and uses therefor |
| US10472361B2 (en) | 2017-08-16 | 2019-11-12 | Bristol-Myers Squibb Company | Toll-like receptor 7 (TLR7) agonists having a benzotriazole moiety, conjugates thereof, and methods and uses therefor |
| US10494370B2 (en) | 2017-08-16 | 2019-12-03 | Bristol-Myers Squibb Company | Toll-like receptor 7 (TLR7) agonists having a pyridine or pyrazine moiety, conjugates thereof, and methods and uses therefor |
| US10508115B2 (en) | 2017-08-16 | 2019-12-17 | Bristol-Myers Squibb Company | Toll-like receptor 7 (TLR7) agonists having heteroatom-linked aromatic moieties, conjugates thereof, and methods and uses therefor |
| JP7312168B2 (ja) | 2017-11-13 | 2023-07-20 | クレッシェンド、バイオロジックス、リミテッド | Cd137に結合するシングルドメイン抗体 |
| GB201802573D0 (en) | 2018-02-16 | 2018-04-04 | Crescendo Biologics Ltd | Therapeutic molecules that bind to LAG3 |
| CN112119157B (zh) | 2018-03-06 | 2025-01-14 | 宾夕法尼亚大学董事会 | 前列腺特异性膜抗原car及其使用方法 |
| WO2019209811A1 (en) | 2018-04-24 | 2019-10-31 | Bristol-Myers Squibb Company | Macrocyclic toll-like receptor 7 (tlr7) agonists |
| AU2019277094B2 (en) | 2018-05-29 | 2025-12-18 | Bristol-Myers Squibb Company | Modified self-immolating moieties for use in prodrugs and conjugates and methods of using and making |
| CA3104098A1 (en) * | 2018-06-21 | 2019-12-26 | Regeneron Pharmaceuticals, Inc. | Bispecific anti-psma x anti-cd28 antibodies and uses thereof |
| US11554120B2 (en) | 2018-08-03 | 2023-01-17 | Bristol-Myers Squibb Company | 1H-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (TLR7) agonists and methods and uses therefor |
| US20220106400A1 (en) | 2018-11-28 | 2022-04-07 | Bristol-Myers Squibb Company | Antibodies comprising modified heavy constant regions |
| BR112021010060B1 (pt) | 2018-11-30 | 2024-03-12 | Bristol-Myers Squibb Company | Anticorpo que compreende uma extensão c-terminal de cadeia leve que contém glutamina, conjugados do mesmo, e método de preparação de conjugados |
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| CN110407939B (zh) * | 2019-03-12 | 2023-09-29 | 广东医科大学附属第二医院 | 一种人源化抗psma单链抗体及其应用 |
| EP4028414A4 (en) * | 2019-09-11 | 2024-01-17 | The Trustees of The University of Pennsylvania | Compositions and methods comprising prostate stem cell antigen (psca) chimeric antigen receptors (cars) |
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| CN113024670A (zh) * | 2019-12-25 | 2021-06-25 | 百奥泰生物制药股份有限公司 | Ctla-4抗体及其制备方法 |
| JP2023532807A (ja) | 2020-07-08 | 2023-07-31 | ラヴァ・セラピューティクス・エヌ・ヴイ | Psma及びガンマ-デルタt細胞受容体に結合する抗体 |
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| JP2026507228A (ja) | 2023-03-03 | 2026-02-27 | アーセナル バイオサイエンシズ インコーポレイテッド | Psma及びca9を標的とするシステム |
| CN116462762B (zh) * | 2023-06-14 | 2023-08-25 | 天健生物制药(天津)有限公司 | 一种抗前列腺特异性抗原单克隆抗体及其应用 |
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| TW202545991A (zh) * | 2024-01-12 | 2025-12-01 | 大陸商信達生物製藥(蘇州)有限公司 | 抗cd28抗體及其用途 |
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| CN120446482B (zh) * | 2025-07-10 | 2025-09-19 | 杭州华得森生物技术有限公司 | 微流控芯片psma前列腺癌循环肿瘤细胞免疫富集检测试剂盒及制备方法 |
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-
2006
- 2006-02-17 WO PCT/US2006/005852 patent/WO2006089230A2/en not_active Ceased
- 2006-02-17 DK DK06735489.4T patent/DK1851250T3/da active
- 2006-02-17 AU AU2006214031A patent/AU2006214031A1/en not_active Abandoned
- 2006-02-17 EP EP06735489A patent/EP1851250B1/en not_active Expired - Lifetime
- 2006-02-17 ES ES06735489T patent/ES2386366T3/es not_active Expired - Lifetime
- 2006-02-17 NZ NZ556661A patent/NZ556661A/en not_active IP Right Cessation
- 2006-02-17 JP JP2007556368A patent/JP2008529556A/ja active Pending
- 2006-02-17 KR KR1020077021333A patent/KR20070115967A/ko not_active Withdrawn
- 2006-02-17 PT PT06735489T patent/PT1851250E/pt unknown
- 2006-02-17 BR BRPI0607757-9A patent/BRPI0607757A2/pt not_active Application Discontinuation
- 2006-02-17 CN CN2006800053479A patent/CN101124249B/zh not_active Expired - Fee Related
- 2006-02-17 CA CA002598522A patent/CA2598522A1/en not_active Abandoned
- 2006-02-17 MX MX2007009878A patent/MX2007009878A/es not_active Application Discontinuation
- 2006-02-17 US US11/918,153 patent/US20090297438A1/en not_active Abandoned
- 2006-02-17 PL PL06735489T patent/PL1851250T3/pl unknown
- 2006-02-17 HR HRP20120709TT patent/HRP20120709T1/hr unknown
-
2007
- 2007-07-19 IL IL184733A patent/IL184733A/en not_active IP Right Cessation
- 2007-07-20 NO NO20073797A patent/NO20073797L/no not_active Application Discontinuation
-
2012
- 2012-09-04 CY CY20121100788T patent/CY1113089T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ556661A (en) | 2010-10-29 |
| EP1851250A2 (en) | 2007-11-07 |
| CY1113089T1 (el) | 2016-04-13 |
| EP1851250B1 (en) | 2012-06-06 |
| NO20073797L (no) | 2007-09-12 |
| CA2598522A1 (en) | 2006-08-24 |
| WO2006089230A2 (en) | 2006-08-24 |
| CN101124249B (zh) | 2011-06-29 |
| JP2008529556A (ja) | 2008-08-07 |
| US20090297438A1 (en) | 2009-12-03 |
| CN101124249A (zh) | 2008-02-13 |
| MX2007009878A (es) | 2007-10-03 |
| PT1851250E (pt) | 2012-08-27 |
| IL184733A0 (en) | 2007-12-03 |
| BRPI0607757A2 (pt) | 2009-10-06 |
| DK1851250T3 (da) | 2012-07-09 |
| HRP20120709T1 (hr) | 2012-10-31 |
| ES2386366T3 (es) | 2012-08-17 |
| WO2006089230A3 (en) | 2006-11-16 |
| AU2006214031A1 (en) | 2006-08-24 |
| KR20070115967A (ko) | 2007-12-06 |
| IL184733A (en) | 2015-07-30 |
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