TR201802090T4 - Kanserin tedavisine yönelik monoklonal anti-GT468 antikorlar. - Google Patents

Kanserin tedavisine yönelik monoklonal anti-GT468 antikorlar. Download PDF

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Publication number
TR201802090T4
TR201802090T4 TR2018/02090T TR201802090T TR201802090T4 TR 201802090 T4 TR201802090 T4 TR 201802090T4 TR 2018/02090 T TR2018/02090 T TR 2018/02090T TR 201802090 T TR201802090 T TR 201802090T TR 201802090 T4 TR201802090 T4 TR 201802090T4
Authority
TR
Turkey
Prior art keywords
cancer
treatment
antibodies
monoclonal anti
neuroblastoma
Prior art date
Application number
TR2018/02090T
Other languages
English (en)
Inventor
Sahin Ugur
Türeci Özlem
Koslowski Michael
Mitnacht-Kraus Rita
Original Assignee
Ganymed Pharmaceuticals Gmbh
Univ Mainz Johannes Gutenberg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ganymed Pharmaceuticals Gmbh, Univ Mainz Johannes Gutenberg filed Critical Ganymed Pharmaceuticals Gmbh
Publication of TR201802090T4 publication Critical patent/TR201802090T4/tr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Mevcut buluş, meme kanseri, akciğer kanseri, gastrik kanser, yumurtalık kanseri, hepatoselüler kanser, kolon kanseri, pankreatik kanser, özofagus kanseri, baş & boyun kanseri, böbrek kanseri, özellikle renal hücreli karsinom, Prostat kanseri, karaciğer kanseri, melanom, sarkoma, miyelom, nöroblastom, plasental koriyokarsinom, servikal kanser, ve tiroit kanseri, ve metastatik formları gibi tümör ilişkili hastalıklar dahil olmak üzere GT468 ifade eden hücreler ile ilişkili hastalıkların tedavi edilmesi ve/veya önlenmesine yönelik terapötikler olarak faydalı antikorları sağlar.
TR2018/02090T 2008-09-16 2009-09-16 Kanserin tedavisine yönelik monoklonal anti-GT468 antikorlar. TR201802090T4 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9745308P 2008-09-16 2008-09-16
EP08016277A EP2166021A1 (en) 2008-09-16 2008-09-16 Monoclonal antibodies for treatment of cancer

Publications (1)

Publication Number Publication Date
TR201802090T4 true TR201802090T4 (tr) 2018-03-21

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
TR2018/02090T TR201802090T4 (tr) 2008-09-16 2009-09-16 Kanserin tedavisine yönelik monoklonal anti-GT468 antikorlar.

Country Status (26)

Country Link
US (1) US8946388B2 (tr)
EP (3) EP2166021A1 (tr)
JP (1) JP2012502938A (tr)
KR (1) KR101818741B1 (tr)
CN (3) CN105753988A (tr)
AU (1) AU2009294896B2 (tr)
BR (1) BRPI0918178B8 (tr)
CA (1) CA2732594C (tr)
CY (1) CY1119956T1 (tr)
DK (1) DK2342234T3 (tr)
ES (1) ES2659718T3 (tr)
HK (1) HK1253579A1 (tr)
HR (1) HRP20180262T1 (tr)
HU (1) HUE036477T2 (tr)
IL (2) IL211010A (tr)
LT (1) LT2342234T (tr)
MX (2) MX2011002856A (tr)
NO (1) NO2342234T3 (tr)
NZ (2) NZ591004A (tr)
PL (1) PL2342234T3 (tr)
PT (1) PT2342234T (tr)
RS (1) RS56937B1 (tr)
SI (1) SI2342234T1 (tr)
TR (1) TR201802090T4 (tr)
WO (1) WO2010031551A2 (tr)
ZA (1) ZA201100835B (tr)

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Also Published As

Publication number Publication date
AU2009294896A1 (en) 2010-03-25
NO2342234T3 (tr) 2018-04-14
DK2342234T3 (en) 2018-02-26
WO2010031551A2 (en) 2010-03-25
IL242204B (en) 2020-09-30
BRPI0918178B8 (pt) 2021-05-25
WO2010031551A3 (en) 2010-09-16
CN104628858B (zh) 2018-11-16
PL2342234T3 (pl) 2018-07-31
EP2342234A2 (en) 2011-07-13
BRPI0918178A2 (pt) 2015-12-01
US20110223182A1 (en) 2011-09-15
HUE036477T2 (hu) 2018-07-30
SI2342234T1 (en) 2018-04-30
ES2659718T3 (es) 2018-03-19
IL242204A0 (en) 2015-11-30
PT2342234T (pt) 2018-02-21
EP2166021A1 (en) 2010-03-24
ZA201100835B (en) 2014-04-30
EP2342234B1 (en) 2017-11-15
BRPI0918178B1 (pt) 2021-04-06
MX2011002856A (es) 2011-06-28
EP3312198A1 (en) 2018-04-25
BRPI0918178A8 (pt) 2020-05-19
JP2012502938A (ja) 2012-02-02
KR20110055699A (ko) 2011-05-25
US8946388B2 (en) 2015-02-03
LT2342234T (lt) 2018-03-12
NZ596490A (en) 2013-05-31
CN105753988A (zh) 2016-07-13
RS56937B1 (sr) 2018-05-31
CY1119956T1 (el) 2018-12-12
CN104628858A (zh) 2015-05-20
HRP20180262T1 (hr) 2018-03-23
KR101818741B1 (ko) 2018-01-15
HK1253579A1 (zh) 2019-06-21
IL211010A0 (en) 2011-04-28
MX357010B (es) 2018-06-22
NZ591004A (en) 2012-03-30
CN102164963B (zh) 2015-07-29
IL211010A (en) 2015-11-30
CN102164963A (zh) 2011-08-24
CA2732594A1 (en) 2010-03-25
AU2009294896B2 (en) 2015-04-30
CA2732594C (en) 2019-05-28

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