JP2014513089A5 - - Google Patents

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JP2014513089A5
JP2014513089A5 JP2014506843A JP2014506843A JP2014513089A5 JP 2014513089 A5 JP2014513089 A5 JP 2014513089A5 JP 2014506843 A JP2014506843 A JP 2014506843A JP 2014506843 A JP2014506843 A JP 2014506843A JP 2014513089 A5 JP2014513089 A5 JP 2014513089A5
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JP
Japan
Prior art keywords
fluorouracil
aflibercept
crc
folinic acid
patient
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JP2014506843A
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English (en)
Japanese (ja)
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JP2014513089A (ja
JP6114257B2 (ja
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Priority claimed from PCT/EP2012/057542 external-priority patent/WO2012146610A1/en
Publication of JP2014513089A publication Critical patent/JP2014513089A/ja
Publication of JP2014513089A5 publication Critical patent/JP2014513089A5/ja
Application granted granted Critical
Publication of JP6114257B2 publication Critical patent/JP6114257B2/ja
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JP2014506843A 2011-04-26 2012-04-25 アフリバーセプト、フォリン酸、5−フルオロウラシル(5−fu)及びイリノセタン(フォルフィリ)を含む組成物 Active JP6114257B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP11305490 2011-04-26
EP11305490.2 2011-04-26
EP11306154 2011-09-15
EP11306154.3 2011-09-15
PCT/EP2012/057542 WO2012146610A1 (en) 2011-04-26 2012-04-25 Composition comprising aflibercept, folinic acid, 5-fluorouracil (5-fu) and irinocetan (folfiri)

Publications (3)

Publication Number Publication Date
JP2014513089A JP2014513089A (ja) 2014-05-29
JP2014513089A5 true JP2014513089A5 (enExample) 2015-04-16
JP6114257B2 JP6114257B2 (ja) 2017-04-12

Family

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JP2014506843A Active JP6114257B2 (ja) 2011-04-26 2012-04-25 アフリバーセプト、フォリン酸、5−フルオロウラシル(5−fu)及びイリノセタン(フォルフィリ)を含む組成物

Country Status (39)

Country Link
US (1) US11033606B2 (enExample)
EP (2) EP3210617A1 (enExample)
JP (1) JP6114257B2 (enExample)
KR (2) KR20190088568A (enExample)
CN (1) CN103608029A (enExample)
AR (1) AR086051A1 (enExample)
AU (1) AU2012247530B2 (enExample)
BR (1) BR112013027356A2 (enExample)
CA (1) CA2833592A1 (enExample)
CL (1) CL2013003082A1 (enExample)
CO (1) CO6811861A2 (enExample)
CR (1) CR20130547A (enExample)
CY (1) CY1120382T1 (enExample)
DK (1) DK2701724T3 (enExample)
DO (1) DOP2013000248A (enExample)
EA (1) EA025182B1 (enExample)
EC (1) ECSP13013044A (enExample)
ES (1) ES2637074T3 (enExample)
GT (1) GT201300260A (enExample)
HR (1) HRP20171216T1 (enExample)
HU (1) HUE034288T2 (enExample)
IL (2) IL228947B (enExample)
JO (1) JO3283B1 (enExample)
LT (1) LT2701724T (enExample)
MA (1) MA35130B1 (enExample)
MX (1) MX341348B (enExample)
NI (1) NI201300112A (enExample)
PE (2) PE20171516A1 (enExample)
PH (1) PH12013502195A1 (enExample)
PL (1) PL2701724T3 (enExample)
PT (1) PT2701724T (enExample)
RS (1) RS56177B1 (enExample)
SG (2) SG10201610829UA (enExample)
SI (1) SI2701724T1 (enExample)
TW (1) TWI599369B (enExample)
UA (1) UA114708C2 (enExample)
UY (1) UY34036A (enExample)
WO (1) WO2012146610A1 (enExample)
ZA (1) ZA201308821B (enExample)

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RS58957B1 (sr) * 2014-07-18 2019-08-30 Sanofi Sa Postupak za predviđanje ishoda tretmana sa afliberceptom kod pacijenta za kog se sumnja da boluje od raka
EA036671B1 (ru) * 2014-09-16 2020-12-07 Ридженерон Фармасьютикалз, Инк. Способ лечения и диагностики метастатического колоректального рака на основании уровня vegf-a
US11318131B2 (en) 2015-05-18 2022-05-03 Ipsen Biopharm Ltd. Nanoliposomal irinotecan for use in treating small cell lung cancer
SG10201913073YA (en) 2015-08-20 2020-03-30 Ipsen Biopharm Ltd Combination therapy using liposomal irinotecan and a parp inhibitor for cancer treatment
SG10201913077QA (en) 2015-08-21 2020-02-27 Ipsen Biopharm Ltd Methods for treating metastatic pancreatic cancer using combination therapies comprising liposomal irinotecan and oxaliplatin
KR101936049B1 (ko) * 2015-10-15 2019-01-08 (주)알테오젠 IgG Fc 도메인을 가지는 융합 단백질의 생산방법
CA3010056A1 (en) 2015-12-30 2017-07-06 Kodiak Sciences Inc. Antibodies and conjugates thereof
EP3408673B1 (en) 2016-01-25 2020-07-08 Sanofi Method for predicting the outcome of a treatment with aflibercept of a patient suspected to suffer from a cancer by measuring the level of a plasma biomarker
BR112019007844A2 (pt) 2016-11-02 2019-07-16 Ipsen Biopharm Ltd tratamento de câncer gástrico usando terapias de combinação compreendendo irinotecano lipossômico, oxaliplatina, 5-fluoroacila (e leucovorina)
CN112203679A (zh) 2018-03-02 2021-01-08 科达制药股份有限公司 Il-6抗体及其融合构建体和缀合物
IL318714A (en) 2018-05-10 2025-03-01 Regeneron Pharma Formulations that include high concentrations of VEGF receptor fusion protein
US20210213020A1 (en) * 2018-05-30 2021-07-15 Inserm (Institut National De La Santé Et De La Rechirche Médicale) Methods and pharmaceutical compositions for treating cancer
WO2021050094A1 (en) * 2019-09-11 2021-03-18 Adverum Biotechnologies, Inc. Methods of treating ocular neovascular diseases using aav2 variants encoding aflibercept
CN114786731A (zh) 2019-10-10 2022-07-22 科达制药股份有限公司 治疗眼部病症的方法

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