EA025182B1 - Композиция, включающая афлиберцепт, фолиновую кислоту, 5-фторурацил (5-fu) и ириноцетан (folfiri), для лечения колоректального рака - Google Patents
Композиция, включающая афлиберцепт, фолиновую кислоту, 5-фторурацил (5-fu) и ириноцетан (folfiri), для лечения колоректального рака Download PDFInfo
- Publication number
- EA025182B1 EA025182B1 EA201391577A EA201391577A EA025182B1 EA 025182 B1 EA025182 B1 EA 025182B1 EA 201391577 A EA201391577 A EA 201391577A EA 201391577 A EA201391577 A EA 201391577A EA 025182 B1 EA025182 B1 EA 025182B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- aflibercept
- patient
- fluorouracil
- dose
- irinocetan
- Prior art date
Links
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- 108010081667 aflibercept Proteins 0.000 title claims abstract description 123
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- VVIAGPKUTFNRDU-UHFFFAOYSA-N 6S-folinic acid Natural products C1NC=2NC(N)=NC(=O)C=2N(C=O)C1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 VVIAGPKUTFNRDU-UHFFFAOYSA-N 0.000 title claims abstract description 35
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Classifications
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11305490 | 2011-04-26 | ||
| EP11306154 | 2011-09-15 | ||
| PCT/EP2012/057542 WO2012146610A1 (en) | 2011-04-26 | 2012-04-25 | Composition comprising aflibercept, folinic acid, 5-fluorouracil (5-fu) and irinocetan (folfiri) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201391577A1 EA201391577A1 (ru) | 2014-03-31 |
| EA025182B1 true EA025182B1 (ru) | 2016-11-30 |
Family
ID=46001286
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201391577A EA025182B1 (ru) | 2011-04-26 | 2012-04-25 | Композиция, включающая афлиберцепт, фолиновую кислоту, 5-фторурацил (5-fu) и ириноцетан (folfiri), для лечения колоректального рака |
Country Status (39)
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO3283B1 (ar) | 2011-04-26 | 2018-09-16 | Sanofi Sa | تركيب يتضمن أفليبيرسيبت, حمض فولينيك, 5- فلورويوراسيل (5- Fu) وإرينوسيتان (FOLFIRI) |
| AU2013202947B2 (en) * | 2012-06-13 | 2016-06-02 | Ipsen Biopharm Ltd. | Methods for treating pancreatic cancer using combination therapies comprising liposomal irinotecan |
| US9717724B2 (en) | 2012-06-13 | 2017-08-01 | Ipsen Biopharm Ltd. | Methods for treating pancreatic cancer using combination therapies |
| KR20150038297A (ko) * | 2012-08-02 | 2015-04-08 | 사노피 | 아플리베르셉트 또는 지브-아플리베르셉트를 포함하는 제조 물품 |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| RS58957B1 (sr) * | 2014-07-18 | 2019-08-30 | Sanofi Sa | Postupak za predviđanje ishoda tretmana sa afliberceptom kod pacijenta za kog se sumnja da boluje od raka |
| EA036671B1 (ru) * | 2014-09-16 | 2020-12-07 | Ридженерон Фармасьютикалз, Инк. | Способ лечения и диагностики метастатического колоректального рака на основании уровня vegf-a |
| US11318131B2 (en) | 2015-05-18 | 2022-05-03 | Ipsen Biopharm Ltd. | Nanoliposomal irinotecan for use in treating small cell lung cancer |
| SG10201913073YA (en) | 2015-08-20 | 2020-03-30 | Ipsen Biopharm Ltd | Combination therapy using liposomal irinotecan and a parp inhibitor for cancer treatment |
| SG10201913077QA (en) | 2015-08-21 | 2020-02-27 | Ipsen Biopharm Ltd | Methods for treating metastatic pancreatic cancer using combination therapies comprising liposomal irinotecan and oxaliplatin |
| KR101936049B1 (ko) * | 2015-10-15 | 2019-01-08 | (주)알테오젠 | IgG Fc 도메인을 가지는 융합 단백질의 생산방법 |
| CA3010056A1 (en) | 2015-12-30 | 2017-07-06 | Kodiak Sciences Inc. | Antibodies and conjugates thereof |
| EP3408673B1 (en) | 2016-01-25 | 2020-07-08 | Sanofi | Method for predicting the outcome of a treatment with aflibercept of a patient suspected to suffer from a cancer by measuring the level of a plasma biomarker |
| BR112019007844A2 (pt) | 2016-11-02 | 2019-07-16 | Ipsen Biopharm Ltd | tratamento de câncer gástrico usando terapias de combinação compreendendo irinotecano lipossômico, oxaliplatina, 5-fluoroacila (e leucovorina) |
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| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): KZ |