|
US11660317B2
(en)
|
2004-11-08 |
2023-05-30 |
The Johns Hopkins University |
Compositions comprising cardiosphere-derived cells for use in cell therapy
|
|
CA2829586C
(en)
*
|
2011-03-11 |
2021-03-02 |
Children's Medical Center Corporation |
Methods and compositions relating to mesenchymal stem cell exosomes
|
|
ITRM20110403A1
(it)
*
|
2011-07-28 |
2013-01-29 |
Ospedale Pediatrico Bambino Gesu |
Microvescicole isolate da cellule mesenchimali come agenti immunosoppressori.
|
|
US9427450B2
(en)
|
2012-01-31 |
2016-08-30 |
Xon Cells, Inc. |
Therapeutic immune modulation by stem cell secreted exosomes
|
|
GB201202319D0
(en)
|
2012-02-10 |
2012-03-28 |
Orbsen Therapeutics Ltd |
Stromal stem cells
|
|
AU2013302799B2
(en)
|
2012-08-13 |
2018-03-01 |
Cedars-Sinai Medical Center |
Exosomes and micro-ribonucleic acids for tissue regeneration
|
|
CN103865873B
(zh)
*
|
2012-12-12 |
2017-04-05 |
中国医学科学院基础医学研究所 |
亚全能干细胞分泌的外来体及其应用
|
|
CN115919901A
(zh)
*
|
2012-12-12 |
2023-04-07 |
麦瑟布莱斯特公司 |
治疗或预防呼吸病症的方法
|
|
CN105264092B
(zh)
*
|
2013-03-15 |
2019-02-22 |
得克萨斯州大学系统董事会 |
用于诊断和疗法的外来体中的miRNA生物发生
|
|
WO2014197421A1
(en)
|
2013-06-05 |
2014-12-11 |
Biotime, Inc. |
Compositions and methods for induced tissue regeneration in mammalian species
|
|
ES2909752T3
(es)
*
|
2013-08-01 |
2022-05-10 |
Swedish Stromabio Ab |
MSC en el tratamiento de enfermedades pulmonares inflamatorias
|
|
GB201317887D0
(en)
|
2013-10-09 |
2013-11-20 |
Reneuron Ltd |
Product
|
|
CN104694466A
(zh)
*
|
2013-12-06 |
2015-06-10 |
山西医科大学 |
间充质干细胞来源的胞外体制备及在急性肺损伤中的应用
|
|
KR101662405B1
(ko)
*
|
2013-12-12 |
2016-10-05 |
사회복지법인 삼성생명공익재단 |
줄기세포 유래 엑소좀을 유효성분으로 포함하는 뇌혈관 질환 치료용 약학적 조성물
|
|
US11078462B2
(en)
|
2014-02-18 |
2021-08-03 |
ReCyte Therapeutics, Inc. |
Perivascular stromal cells from primate pluripotent stem cells
|
|
US9919011B2
(en)
|
2014-03-18 |
2018-03-20 |
Samsung Life Public Welfare Foundation |
Method for treating an inflammatory brain disease comprising administering a stem cell-derived exosome
|
|
CA2949083C
(en)
|
2014-05-18 |
2023-10-10 |
Children's Medical Center Corporation |
Methods and compositions relating to exosomes
|
|
WO2015191545A1
(en)
*
|
2014-06-09 |
2015-12-17 |
University Of Washington |
Methods of protection against ischemia reperfusion injury
|
|
WO2016001846A1
(en)
*
|
2014-06-30 |
2016-01-07 |
Tigenix S.A.U. |
Mesenchymal stromal cells for treating sepsis
|
|
US10240127B2
(en)
|
2014-07-03 |
2019-03-26 |
ReCyte Therapeutics, Inc. |
Exosomes from clonal progenitor cells
|
|
EP3209768A1
(en)
|
2014-07-25 |
2017-08-30 |
Recellerate Inc. |
Methods of treating exercise-induced pulmonary hemorrhage
|
|
CA2962444C
(en)
|
2014-10-03 |
2023-09-05 |
Cedars-Sinai Medical Center |
Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy
|
|
EP3204117A4
(en)
*
|
2014-10-06 |
2018-05-09 |
Cedars-Sinai Medical Center |
Polarization of macrophages to a healing phenotype by cardiosphere-derived cells and by the exosomes secreted by such cells
|
|
WO2016072821A1
(ko)
*
|
2014-11-07 |
2016-05-12 |
한양대학교 에리카산학협력단 |
줄기세포 유래 엑소좀을 함유하는 지방세포 분화유도, 지방조직 재생, 피부 미백 또는 주름개선용 조성물
|
|
JP6683700B2
(ja)
*
|
2014-11-07 |
2020-04-22 |
株式会社エキソステムテックＥｘｏｓｔｅｍｔｅｃｈ Ｃｏ．，Ｌｔｄ． |
幹細胞由来のエキソソームを含有する脂肪細胞分化誘導、または脂肪組織の再生用組成物の製造方法
|
|
JP6716564B2
(ja)
*
|
2014-12-03 |
2020-07-01 |
カプリコール，インコーポレイテッド |
安定したエクソソーム製剤の製造方法
|
|
CN104560877B
(zh)
*
|
2014-12-18 |
2017-07-28 |
福州市传染病医院 |
一种快速分离细胞外吐小体的方法
|
|
US20180264047A1
(en)
*
|
2014-12-24 |
2018-09-20 |
Ube Industries, Ltd. |
Cell culture supernatant fluid derived from lung tissue
|
|
WO2016111899A1
(en)
*
|
2015-01-05 |
2016-07-14 |
Petrucci Gary M |
Methods and materials for treating lung disorders
|
|
US20180325830A1
(en)
|
2017-05-09 |
2018-11-15 |
Vivex Biomedical, Inc. |
Coated biological composition
|
|
US11160904B2
(en)
*
|
2017-05-09 |
2021-11-02 |
Vivex Biologies Group, Inc. |
Biological composition in a protectant shroud and methods
|
|
US9687511B2
(en)
|
2015-03-06 |
2017-06-27 |
Vivex Biomedical, Inc. |
Acellular biologic composition and method of manufacture
|
|
KR101566450B1
(ko)
*
|
2015-04-03 |
2015-11-05 |
(유)스템메디케어 |
중간엽 줄기세포에서 단백질의 대량 생산 방법
|
|
US11160834B2
(en)
|
2015-04-28 |
2021-11-02 |
The Texas A&M University System |
Scalable production of standardized extracellular vesicles, extracellular vesicle preparations and uses thereof
|
|
US20180177727A1
(en)
*
|
2015-06-10 |
2018-06-28 |
Board Of Regents, The University Of Texas System |
Use of exosomes for the treatment of disease
|
|
US11320441B2
(en)
|
2015-06-10 |
2022-05-03 |
Children's National Medical Center |
Adipocyte-derived exosomes, and compositions, kits, and methods of using the same for detection and screening
|
|
CN114984054B
(zh)
*
|
2015-06-12 |
2025-04-01 |
哈德逊医学研究中心 |
一种治疗方法
|
|
US11077147B2
(en)
*
|
2015-07-20 |
2021-08-03 |
Vivex Biologics Group, Inc. |
Acellular biologic composition and method of manufacture
|
|
WO2017023690A1
(en)
*
|
2015-07-31 |
2017-02-09 |
Exoceuticals, Inc. |
Exosome compositions and methods for preparation and use thereof for regulating and conditioning skin and hair
|
|
CA3202332A1
(en)
|
2015-12-07 |
2017-06-15 |
Agex Therapeutics, Inc. |
Methods for the re-derivation of diverse pluripotent stem cell-derived brown fat cells
|
|
EP3402543B1
(en)
|
2016-01-11 |
2021-09-08 |
Cedars-Sinai Medical Center |
Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction
|
|
EP3922253A1
(en)
*
|
2016-01-15 |
2021-12-15 |
Orbsen Therapeutics Limited |
Sdc-2 exosome compositions and methods of isolation and use
|
|
EP3407844A4
(en)
|
2016-01-29 |
2019-10-16 |
Qool Therapeutics, Inc. |
AEROSOLISATION OF STEM CELLS OR STEM CELL DERIVATIVES FOR PULMONARY ADMINISTRATION
|
|
KR101843634B1
(ko)
*
|
2016-04-15 |
2018-03-30 |
사회복지법인 삼성생명공익재단 |
트롬빈 처리 줄기세포에서 유래된 엑소좀을 포함하는 만성폐질환 치료용 조성물
|
|
WO2017210652A1
(en)
|
2016-06-03 |
2017-12-07 |
Cedars-Sinai Medical Center |
Cdc-derived exosomes for treatment of ventricular tachyarrythmias
|
|
KR20250037589A
(ko)
*
|
2016-06-17 |
2025-03-17 |
유나이티드 쎄러퓨틱스 코포레이션 |
향상된 효능을 가진 세포외 소포
|
|
US10946047B2
(en)
*
|
2016-06-17 |
2021-03-16 |
United Therapeutics Corporation |
Extracellular vesicles with enhanced potency
|
|
KR102503101B1
(ko)
*
|
2016-08-03 |
2023-02-23 |
고쿠리츠 다이가쿠 호우징 도우카이 고쿠리츠 다이가쿠 기코우 |
다능성 간세포에 따른 만성폐질환의 개선 및 치료
|
|
CA3032925A1
(en)
*
|
2016-08-03 |
2018-02-08 |
Life Science Institute, Inc. |
Alleviation and treatment of ischemia reperfusion-induced lung injury using pluripotent stem cells
|
|
EP3494977A4
(en)
*
|
2016-08-05 |
2020-03-18 |
Exostemtech Co., Ltd. |
COMPOSITION FOR THE PREVENTION OR TREATMENT OF LUNG FIBROSE WITH FAT TISSUE EXOSOM OBTAINED FROM STEM CELLS AS AN ACTIVE SUBSTANCE
|
|
US11541078B2
(en)
|
2016-09-20 |
2023-01-03 |
Cedars-Sinai Medical Center |
Cardiosphere-derived cells and their extracellular vesicles to retard or reverse aging and age-related disorders
|
|
WO2018071677A1
(en)
*
|
2016-10-13 |
2018-04-19 |
Vbc Holdings Llc |
Medical uses of exosomes
|
|
CN110072991A
(zh)
*
|
2016-10-13 |
2019-07-30 |
Vbc控股有限责任公司 |
来源于发炎的细胞或组织的抗炎外泌体
|
|
JP7248984B2
(ja)
*
|
2017-02-28 |
2023-03-30 |
ユニバーシティ デ ロライン |
敗血症の治療のための、ワルトンジェリーから取得された間葉系幹細胞
|
|
US20180291336A1
(en)
*
|
2017-04-07 |
2018-10-11 |
Robert John Petcavich |
Method of manufacturing and purifying exosomes from non-terminally differentiated cells
|
|
EP4699658A2
(en)
|
2017-04-19 |
2026-02-25 |
Cedars-Sinai Medical Center |
Methods and compositions for treating skeletal muscular dystrophy
|
|
TWI704923B
(zh)
*
|
2017-06-26 |
2020-09-21 |
台灣基督長老教會馬偕醫療財團法人馬偕紀念醫院 |
包含胞外囊泡之製劑、用以製備該製劑之方法及其用途
|
|
US12377120B2
(en)
|
2017-07-06 |
2025-08-05 |
Children's National Medical Center |
Exosomes and methods of use thereof
|
|
KR20190011213A
(ko)
*
|
2017-07-24 |
2019-02-01 |
한양대학교 에리카산학협력단 |
줄기세포로부터 추출된 엑소좀을 유효성분으로 포함하는 골다공증 예방 또는 치료용 조성물
|
|
CA3072562A1
(en)
|
2017-08-15 |
2019-02-21 |
Children's Medical Center Corporation |
Purified mesenchymal stem cell exosomes and uses thereof
|
|
US11471559B2
(en)
*
|
2017-11-20 |
2022-10-18 |
Vivex Biologics Group, Inc. |
Bioenergetic bone
|
|
US11660355B2
(en)
|
2017-12-20 |
2023-05-30 |
Cedars-Sinai Medical Center |
Engineered extracellular vesicles for enhanced tissue delivery
|
|
US12146137B2
(en)
|
2018-02-05 |
2024-11-19 |
Cedars-Sinai Medical Center |
Methods for therapeutic use of exosomes and Y-RNAS
|
|
CN112334190B
(zh)
|
2018-04-30 |
2024-09-20 |
儿童医学中心公司 |
间充质基质细胞外排体及其用途
|
|
US12031976B2
(en)
|
2018-05-04 |
2024-07-09 |
Samsung Life Public Welfare Foundation |
Screening method for therapeutic substance for preventing or treating bronchopulmonary dysplasia (BPD)
|
|
JP2021526556A
(ja)
*
|
2018-05-30 |
2021-10-07 |
ダイレクト バイオロジクス エルエルシー |
成長因子および細胞外小胞を凍結または粉状にした、間葉系幹細胞（ｍｓｃ）の調製物を含む助剤、ならびにその使用方法
|
|
KR102863376B1
(ko)
*
|
2018-06-11 |
2025-09-24 |
헬스 앤드 바이오테크 프랑스 (에이치 앤드 비 프랑스) |
중간엽 줄기 세포로부터 유래된 세포외 소포
|
|
EP3813858B1
(en)
*
|
2018-06-29 |
2023-11-01 |
North Carolina State University |
Therapeutic lung repair by inhalation of lung spheroid exosomes
|
|
AU2019312212B2
(en)
*
|
2018-07-24 |
2024-10-10 |
Mayo Foundation For Medical Education And Research |
Compositions and methods involving transforming extracellular vesicles
|
|
MA53273A
(fr)
|
2018-08-10 |
2021-06-16 |
Omnispirant Ltd |
Vésicules extracellulaires pour inhalation
|
|
EP3879980A4
(en)
*
|
2018-11-15 |
2022-08-24 |
Washington University |
EXTRACELLULAR VESICLES DERIVED FROM STEM CELLS AND METHODS OF USE THEREOF
|
|
BR112021015549A2
(pt)
|
2019-02-07 |
2021-10-26 |
Direct Biologics Llc |
Método para tratar osteoartrite com uma combinação de exossomos de células tronco mesenquimais, células tronco mesenquimais sinoviais e andaimes
|
|
AU2020228303B2
(en)
*
|
2019-02-28 |
2025-09-18 |
Merakris Therapeutics Llc |
Amniotic fluid-derived extracellular vesicles and uses thereof for wound healing
|
|
JP7372518B2
(ja)
*
|
2019-06-27 |
2023-11-01 |
国立大学法人山口大学 |
骨髄由来間葉系幹細胞の培養方法
|
|
CA3146433A1
(en)
|
2019-07-18 |
2021-01-21 |
Direct Biologics Llc |
Preparations comprising mesenchymal stem cells and cannabinoids and methods of their use
|
|
CN114269358A
(zh)
*
|
2019-07-31 |
2022-04-01 |
上海圣特佳健康科技发展有限公司 |
针对纤维化、炎症、和/或老化疾病的治疗药物
|
|
US20210052641A1
(en)
*
|
2019-08-23 |
2021-02-25 |
United Therapeutics Corporation |
Pre-conditioned extracellular vesicles and methods of production
|
|
CN110777113B
(zh)
*
|
2019-09-10 |
2021-09-24 |
中山大学 |
一种用于日本血吸虫感染治疗的间质干细胞处理方法
|
|
CA3163871A1
(en)
*
|
2019-12-04 |
2021-06-10 |
United Therapeutics Corporation |
Extracellular vesicles and their uses
|
|
CN113384597A
(zh)
*
|
2020-03-13 |
2021-09-14 |
西比曼生物科技（上海）有限公司 |
含人体细胞衍生的细胞膜外囊泡的雾化吸入制剂、制法及其应用
|
|
CN111346110A
(zh)
*
|
2020-03-17 |
2020-06-30 |
遵义医学院附属医院 |
间充质干细胞上清液在制备治疗肺细胞损伤制剂中的应用
|
|
US12590310B2
(en)
|
2020-04-22 |
2026-03-31 |
Direct Biologics, Llc |
Methods and compositions for treating inflammatory conditions associated with infectious disease
|
|
EP4179072B1
(en)
*
|
2020-07-09 |
2025-09-03 |
Exo Biologics Sa |
Process for the manufacturing of protein-associated extracellular vesicles
|
|
US20230248773A1
(en)
|
2020-07-09 |
2023-08-10 |
Exo Biologics Sa |
Extracellular Vesicles and Compositions Thereof
|
|
WO2022018729A1
(en)
*
|
2020-07-20 |
2022-01-27 |
Brainstorm Cell Therapeutics Ltd. |
Methods and compositions for treating lung conditions
|
|
CN112043686A
(zh)
*
|
2020-09-21 |
2020-12-08 |
沈阳三禾生物科技有限公司 |
脐带间充质干细胞外泌体雾化液在制备治疗哮喘产品中的应用
|
|
CN112007049A
(zh)
*
|
2020-09-21 |
2020-12-01 |
济南磐升生物技术有限公司 |
一种用于治疗膝骨关节炎的干细胞外泌体组合物
|
|
EP4240323A1
(en)
*
|
2020-11-06 |
2023-09-13 |
AATEC Medical GmbH |
A composition comprising extra-cellular vesicles from mesenchymal stem cells and alpha-1 antitrypsin for the treatment of viral infections
|
|
EP3995130A1
(en)
*
|
2020-11-06 |
2022-05-11 |
JunctuCell Biomed Manufacturing GmbH |
A composition comprising extra-cellular vesicles from mesenchymal stem cells and alpha-1 antitrypsin for the treatment of viral infections
|
|
EP4252761A4
(en)
*
|
2020-11-26 |
2024-06-05 |
Samsung Life Public Welfare Foundation |
COMPOSITION FOR THE TREATMENT OF INFECTIOUS DISEASES, COMPRISING EXOSOMES DERIVED FROM THROMBIN-PROCESSED STEM CELLS
|
|
USD1046870S1
(en)
|
2020-12-08 |
2024-10-15 |
Samsung Electronics Co., Ltd. |
Accessory panel for television receiver
|
|
CN112675203A
(zh)
*
|
2021-02-08 |
2021-04-20 |
瑞太生物科技(沈阳)有限公司 |
一种细胞来源的外泌体在制备治疗哮喘和/或肺纤维化生物制剂中的应用
|
|
US20240376434A1
(en)
|
2021-09-16 |
2024-11-14 |
Life Technologies Corporation |
Cell expansion methods and compositions for use therein
|
|
JP7773257B2
(ja)
|
2022-03-28 |
2025-11-19 |
合同会社HiRoko Science |
ｍｉＲ－１４０を含む医薬組成物及びその製造方法
|
|
CN115725499B
(zh)
*
|
2022-08-15 |
2025-08-15 |
哈尔滨医科大学 |
一种人脐带间充质干细胞膜仿生纳米囊泡的制备方法和应用
|
|
CN116897887A
(zh)
*
|
2023-07-31 |
2023-10-20 |
湖南中医药大学 |
一种病毒性哮喘动物模型的构建方法
|
|
US12502407B2
(en)
|
2024-04-25 |
2025-12-23 |
Direct Biologics, Llc |
Treatment of fistula with bone marrow mesenchymal stem cell derived extracellular vesicles
|
|
WO2025250774A1
(en)
*
|
2024-05-31 |
2025-12-04 |
Leksum LLC |
Extracellular vesicles for therapy
|