JP2012512815A5 - - Google Patents
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- Publication number
- JP2012512815A5 JP2012512815A5 JP2011541030A JP2011541030A JP2012512815A5 JP 2012512815 A5 JP2012512815 A5 JP 2012512815A5 JP 2011541030 A JP2011541030 A JP 2011541030A JP 2011541030 A JP2011541030 A JP 2011541030A JP 2012512815 A5 JP2012512815 A5 JP 2012512815A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- antagonist
- composition according
- subject
- csf
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13967908P | 2008-12-22 | 2008-12-22 | |
| US61/139,679 | 2008-12-22 | ||
| US16448609P | 2009-03-30 | 2009-03-30 | |
| US61/164,486 | 2009-03-30 | ||
| PCT/AU2009/001672 WO2010071924A1 (en) | 2008-12-22 | 2009-12-21 | Osteoarthritis treatment |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015031198A Division JP2015143233A (ja) | 2008-12-22 | 2015-02-20 | 変形性関節症の治療 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012512815A JP2012512815A (ja) | 2012-06-07 |
| JP2012512815A5 true JP2012512815A5 (https=) | 2013-02-14 |
| JP5727379B2 JP5727379B2 (ja) | 2015-06-03 |
Family
ID=42286786
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011541030A Active JP5727379B2 (ja) | 2008-12-22 | 2009-12-21 | 変形性関節症の治療 |
| JP2015031198A Pending JP2015143233A (ja) | 2008-12-22 | 2015-02-20 | 変形性関節症の治療 |
| JP2017114806A Active JP6458086B2 (ja) | 2008-12-22 | 2017-06-12 | 変形性関節症の治療 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015031198A Pending JP2015143233A (ja) | 2008-12-22 | 2015-02-20 | 変形性関節症の治療 |
| JP2017114806A Active JP6458086B2 (ja) | 2008-12-22 | 2017-06-12 | 変形性関節症の治療 |
Country Status (19)
| Country | Link |
|---|---|
| US (4) | US9243061B2 (https=) |
| EP (2) | EP3056217B1 (https=) |
| JP (3) | JP5727379B2 (https=) |
| KR (2) | KR101898982B1 (https=) |
| CN (2) | CN102271705A (https=) |
| AU (1) | AU2009329814B2 (https=) |
| BR (1) | BRPI0918356B1 (https=) |
| CA (1) | CA2746827C (https=) |
| CY (1) | CY1117698T1 (https=) |
| DK (1) | DK2376121T4 (https=) |
| ES (2) | ES2572368T5 (https=) |
| HK (1) | HK1226938A1 (https=) |
| HR (1) | HRP20160577T4 (https=) |
| HU (1) | HUE028615T2 (https=) |
| PL (1) | PL2376121T5 (https=) |
| RU (2) | RU2712273C2 (https=) |
| SI (2) | SI2376121T1 (https=) |
| SM (1) | SMT201600156B (https=) |
| WO (1) | WO2010071924A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2630969C2 (ru) | 2008-12-22 | 2017-09-15 | Де Юниверсити Оф Мельбурн | Лечение боли |
| EP3056217B1 (en) * | 2008-12-22 | 2021-06-30 | The University of Melbourne | Osteoarthritis treatment |
| EP3345923A1 (en) | 2012-09-20 | 2018-07-11 | MorphoSys AG | Treatment for rheumatoid arthritis with anti-gm-csf antibody |
| DE102013222200A1 (de) * | 2013-10-31 | 2015-08-27 | Osram Opto Semiconductors Gmbh | Elektronisches Bauelement und Verfahren zum Herstellen eines elektronischen Bauelements |
| IL301622A (en) * | 2017-08-14 | 2023-05-01 | Zynerba Pharmaceuticals Inc | Methods for treating degenerative joint disease with cannabidiol gel through the skin |
| WO2020104833A1 (en) * | 2018-11-19 | 2020-05-28 | 4P-Pharma | Composition and methods for regulating chondrocyte proliferation and increasing of cartilage matrix production |
| CN110075304B (zh) * | 2019-05-29 | 2020-02-11 | 四川大学华西医院 | 一种治疗骨关节炎的药物组合物及其用途 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5225539A (en) * | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| AU630496B2 (en) | 1989-07-14 | 1992-10-29 | Schering Corporation | Antagonists of gm-csf derived from the carboxyl terminus |
| WO1991002063A1 (en) | 1989-08-11 | 1991-02-21 | Amrad Corporation Limited | Improvements in granulocyte-macrophage colony-stimulating factor receptor and derivatives thereof |
| WO1994009149A1 (en) | 1990-08-10 | 1994-04-28 | Amrad Corporation Limited | Monoclonal antibody |
| CA2149881A1 (en) | 1992-11-19 | 1994-05-26 | Paul T. Jubinsky | Antibodies for gm-csf receptor and uses thereof |
| AU725609C (en) | 1995-08-18 | 2002-01-03 | Morphosys Ag | Protein/(poly)peptide libraries |
| AUPP525198A0 (en) | 1998-08-13 | 1998-09-03 | Medvet Science Pty. Ltd. | Monoclonal antibody inhibitor of GM-CSF, IL-3 and IL-5 and other cytokines and uses thereof |
| US7108852B2 (en) | 2000-03-20 | 2006-09-19 | Warner-Lambert Company Llc | Methods of treating inflammation using antibodies to M-CSF |
| US7455836B2 (en) * | 2000-05-08 | 2008-11-25 | The University Of Melbourne | Method of treatment and agents useful for same |
| EP1442132A2 (en) * | 2001-10-26 | 2004-08-04 | Novartis AG | Methods for the treatment of osteoarthritis and compositions thereof |
| US7381801B2 (en) | 2002-02-13 | 2008-06-03 | Ludwig Institute For Cancer Research | Chimerized GM-CSF antibodies |
| US20040241755A1 (en) * | 2003-06-02 | 2004-12-02 | Pfizer Inc. | Human cell assay to determine effect of sample compounds on Col2 enhancer expression |
| BRPI0506679A (pt) | 2004-02-11 | 2007-05-15 | Warner Lambert Co | métodos de tratar osteoartrite com antagonistas de il-6 |
| CN1960758B (zh) * | 2004-03-31 | 2014-10-22 | 中外制药株式会社 | 关节炎的治疗剂或预防剂 |
| EP1593690B1 (en) | 2004-05-05 | 2009-07-01 | Micromet AG | Preparation of ScFv antibody fragments |
| EP1782074A2 (en) * | 2004-08-18 | 2007-05-09 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Biomarkers for osteoarthritis |
| US20060040258A1 (en) | 2004-08-23 | 2006-02-23 | Huiyan Guo | Water-soluble conjugates and methods of preparation |
| EP2468774A3 (en) | 2005-04-18 | 2013-01-02 | Amgen Research (Munich) GmbH | Antibody neutralizers of human granulocyte macrophage colony stimulating factor |
| EP3620171B1 (en) * | 2005-05-18 | 2022-04-20 | MorphoSys AG | Anti-gm-csf antibodies and uses therefor |
| JP4736037B2 (ja) | 2005-10-26 | 2011-07-27 | 株式会社イーベック | ヒトｇｍ−ｃｓｆに結合するヒトのモノクローナル抗体並びにその抗原結合部分 |
| EA200801166A1 (ru) * | 2005-12-01 | 2008-12-30 | Домантис Лимитед | Форматы конкурентного доменного антитела, которые связываются с рецептором интерлейкина 1 первого типа |
| CA2641169C (en) * | 2006-02-08 | 2017-05-02 | Morphotek, Inc. | Antigenic gm-csf peptides and antibodies to gm-csf |
| PL1999152T3 (pl) | 2006-03-27 | 2013-05-31 | Medimmune Ltd | Element wiążący receptor GM-CSF |
| US7741273B2 (en) | 2006-04-13 | 2010-06-22 | Warsaw Orthopedic, Inc. | Drug depot implant designs |
| US20080206241A1 (en) * | 2006-11-21 | 2008-08-28 | Kalobios Pharmaceuticals Inc. | Methods of Treating Chronic Inflammatory Diseases Using a GM-CSF Antagonist |
| WO2008080134A2 (en) * | 2006-12-22 | 2008-07-03 | Rigel Pharmaceuticals, Inc. | 4-amin0-2- (hetero) arylamino-5- (hetero) arylthiazoles useful as axl inhibitors |
| WO2008141391A1 (en) | 2007-05-23 | 2008-11-27 | Crc For Asthma And Airways Ltd | Neutralizing antibodies |
| TW200918553A (en) * | 2007-09-18 | 2009-05-01 | Amgen Inc | Human GM-CSF antigen binding proteins |
| WO2009042854A1 (en) * | 2007-09-26 | 2009-04-02 | Musculoskeletal Research Llc | Ion-channel regulator compositions and methods of using same |
| EP2217626A4 (en) | 2007-11-12 | 2011-06-22 | Crc For Asthma And Airways Ltd | EPITOP FOR NEUTRALIZING ANTIBODIES |
| PE20091420A1 (es) | 2007-11-13 | 2009-10-17 | Evec Inc | ANTICUERPOS MONOCLONALES ANTI hGM-CSF |
| US20100040630A1 (en) | 2008-03-24 | 2010-02-18 | Aake Elden | Methods and compositions for treating bone loss |
| NZ588850A (en) | 2008-04-28 | 2012-12-21 | Kalobios Pharmaceuticals Inc | Antibodies to granulocyte-macrophage colony-stimulating factor |
| RU2630969C2 (ru) | 2008-12-22 | 2017-09-15 | Де Юниверсити Оф Мельбурн | Лечение боли |
| EP3056217B1 (en) * | 2008-12-22 | 2021-06-30 | The University of Melbourne | Osteoarthritis treatment |
| CN102459340A (zh) | 2009-04-23 | 2012-05-16 | 特罗科隆科学有限公司 | 粒性白血细胞-巨噬细胞菌落-刺激因子(gm-csf)中和抗体 |
-
2009
- 2009-12-21 EP EP15194091.3A patent/EP3056217B1/en active Active
- 2009-12-21 KR KR1020177032850A patent/KR101898982B1/ko active Active
- 2009-12-21 RU RU2016102339A patent/RU2712273C2/ru active
- 2009-12-21 SI SI200931446A patent/SI2376121T1/sl unknown
- 2009-12-21 US US13/140,467 patent/US9243061B2/en active Active
- 2009-12-21 CA CA2746827A patent/CA2746827C/en active Active
- 2009-12-21 CN CN2009801516359A patent/CN102271705A/zh active Pending
- 2009-12-21 CN CN201610822096.9A patent/CN106397591A/zh active Pending
- 2009-12-21 ES ES09833924T patent/ES2572368T5/es active Active
- 2009-12-21 SI SI200931446T patent/SI2376121T2/sl unknown
- 2009-12-21 ES ES15194091T patent/ES2886063T3/es active Active
- 2009-12-21 KR KR1020117017015A patent/KR101799264B1/ko active Active
- 2009-12-21 RU RU2011127334/15A patent/RU2011127334A/ru unknown
- 2009-12-21 EP EP09833924.5A patent/EP2376121B2/en active Active
- 2009-12-21 WO PCT/AU2009/001672 patent/WO2010071924A1/en not_active Ceased
- 2009-12-21 PL PL09833924T patent/PL2376121T5/pl unknown
- 2009-12-21 AU AU2009329814A patent/AU2009329814B2/en active Active
- 2009-12-21 HR HRP20160577TT patent/HRP20160577T4/hr unknown
- 2009-12-21 JP JP2011541030A patent/JP5727379B2/ja active Active
- 2009-12-21 DK DK09833924.5T patent/DK2376121T4/da active
- 2009-12-21 HU HUE09833924A patent/HUE028615T2/en unknown
- 2009-12-21 BR BRPI0918356-6A patent/BRPI0918356B1/pt active IP Right Grant
-
2015
- 2015-02-20 JP JP2015031198A patent/JP2015143233A/ja active Pending
- 2015-12-18 US US14/975,024 patent/US20160185868A1/en not_active Abandoned
-
2016
- 2016-05-18 CY CY20161100433T patent/CY1117698T1/el unknown
- 2016-06-01 SM SM201600156T patent/SMT201600156B/it unknown
- 2016-12-06 HK HK16113893.3A patent/HK1226938A1/en unknown
-
2017
- 2017-06-12 JP JP2017114806A patent/JP6458086B2/ja active Active
- 2017-11-13 US US15/811,279 patent/US20180066062A1/en not_active Abandoned
-
2020
- 2020-03-31 US US16/836,464 patent/US20200247895A1/en not_active Abandoned
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