JP2012512815A5 - - Google Patents

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Publication number
JP2012512815A5
JP2012512815A5 JP2011541030A JP2011541030A JP2012512815A5 JP 2012512815 A5 JP2012512815 A5 JP 2012512815A5 JP 2011541030 A JP2011541030 A JP 2011541030A JP 2011541030 A JP2011541030 A JP 2011541030A JP 2012512815 A5 JP2012512815 A5 JP 2012512815A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
antagonist
composition according
subject
csf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2011541030A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012512815A (ja
JP5727379B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/AU2009/001672 external-priority patent/WO2010071924A1/en
Publication of JP2012512815A publication Critical patent/JP2012512815A/ja
Publication of JP2012512815A5 publication Critical patent/JP2012512815A5/ja
Application granted granted Critical
Publication of JP5727379B2 publication Critical patent/JP5727379B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2011541030A 2008-12-22 2009-12-21 変形性関節症の治療 Active JP5727379B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US13967908P 2008-12-22 2008-12-22
US61/139,679 2008-12-22
US16448609P 2009-03-30 2009-03-30
US61/164,486 2009-03-30
PCT/AU2009/001672 WO2010071924A1 (en) 2008-12-22 2009-12-21 Osteoarthritis treatment

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015031198A Division JP2015143233A (ja) 2008-12-22 2015-02-20 変形性関節症の治療

Publications (3)

Publication Number Publication Date
JP2012512815A JP2012512815A (ja) 2012-06-07
JP2012512815A5 true JP2012512815A5 (https=) 2013-02-14
JP5727379B2 JP5727379B2 (ja) 2015-06-03

Family

ID=42286786

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2011541030A Active JP5727379B2 (ja) 2008-12-22 2009-12-21 変形性関節症の治療
JP2015031198A Pending JP2015143233A (ja) 2008-12-22 2015-02-20 変形性関節症の治療
JP2017114806A Active JP6458086B2 (ja) 2008-12-22 2017-06-12 変形性関節症の治療

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2015031198A Pending JP2015143233A (ja) 2008-12-22 2015-02-20 変形性関節症の治療
JP2017114806A Active JP6458086B2 (ja) 2008-12-22 2017-06-12 変形性関節症の治療

Country Status (19)

Country Link
US (4) US9243061B2 (https=)
EP (2) EP3056217B1 (https=)
JP (3) JP5727379B2 (https=)
KR (2) KR101898982B1 (https=)
CN (2) CN102271705A (https=)
AU (1) AU2009329814B2 (https=)
BR (1) BRPI0918356B1 (https=)
CA (1) CA2746827C (https=)
CY (1) CY1117698T1 (https=)
DK (1) DK2376121T4 (https=)
ES (2) ES2886063T3 (https=)
HK (1) HK1226938A1 (https=)
HR (1) HRP20160577T4 (https=)
HU (1) HUE028615T2 (https=)
PL (1) PL2376121T5 (https=)
RU (2) RU2712273C2 (https=)
SI (2) SI2376121T1 (https=)
SM (1) SMT201600156B (https=)
WO (1) WO2010071924A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102271705A (zh) * 2008-12-22 2011-12-07 墨尔本大学 骨关节炎治疗
CA2747206C (en) 2008-12-22 2018-04-24 The University Of Melbourne Pain treatment
MA37946B1 (fr) 2012-09-20 2018-09-28 Morphosys Ag Utilisation d’un anticorps anti-gm-csf pour le traitement de la polyarthrite rhumatoïde
DE102013222200A1 (de) * 2013-10-31 2015-08-27 Osram Opto Semiconductors Gmbh Elektronisches Bauelement und Verfahren zum Herstellen eines elektronischen Bauelements
JP2020530857A (ja) * 2017-08-14 2020-10-29 ジナーバ・ファーマシューティカルズ・インコーポレイテッド 経皮カンナビジオールゲルを用いた変形性関節症の治療方法
WO2020104833A1 (en) * 2018-11-19 2020-05-28 4P-Pharma Composition and methods for regulating chondrocyte proliferation and increasing of cartilage matrix production
CN110075304B (zh) * 2019-05-29 2020-02-11 四川大学华西医院 一种治疗骨关节炎的药物组合物及其用途

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US5225539A (en) * 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
EP0482086A1 (en) 1989-07-14 1992-04-29 Schering Corporation Antagonists of gm-csf derived from the carboxyl terminus
EP0486572B1 (en) 1989-08-11 1998-01-07 Amrad Corporation Limited Improvements in granulocyte-macrophage colony-stimulating factor receptor and derivatives thereof
WO1994009149A1 (en) 1990-08-10 1994-04-28 Amrad Corporation Limited Monoclonal antibody
AU5611394A (en) 1992-11-19 1994-06-08 Dana-Farber Cancer Institute Antibodies for gm-csf receptor and uses thereof
ES2176484T3 (es) 1995-08-18 2002-12-01 Morphosys Ag Bancos de proteinas/(poli)peptidos.
AUPP525198A0 (en) 1998-08-13 1998-09-03 Medvet Science Pty. Ltd. Monoclonal antibody inhibitor of GM-CSF, IL-3 and IL-5 and other cytokines and uses thereof
US7108852B2 (en) 2000-03-20 2006-09-19 Warner-Lambert Company Llc Methods of treating inflammation using antibodies to M-CSF
US7455836B2 (en) * 2000-05-08 2008-11-25 The University Of Melbourne Method of treatment and agents useful for same
EP1442132A2 (en) * 2001-10-26 2004-08-04 Novartis AG Methods for the treatment of osteoarthritis and compositions thereof
JP2006500905A (ja) 2002-02-13 2006-01-12 ルードヴィッヒ インスティテュート フォー キャンサー リサーチ ヒト化ｇｍ−ｃｓｆ抗体
US20040241755A1 (en) * 2003-06-02 2004-12-02 Pfizer Inc. Human cell assay to determine effect of sample compounds on Col2 enhancer expression
ATE464908T1 (de) † 2004-02-11 2010-05-15 Warner Lambert Co Verfahren zur behandlung von osteoarthritis mit anti-il-6 antikörpern
ES2465141T3 (es) * 2004-03-31 2014-06-05 Kazuwa Nakao Remedio o medicamento preventivo para la artritis
ATE435238T1 (de) 2004-05-05 2009-07-15 Micromet Ag Herstellung eines einkettigen fv antikörperfragments
WO2006023412A2 (en) 2004-08-18 2006-03-02 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Biomarkers for osteoarthritis
US20060040258A1 (en) 2004-08-23 2006-02-23 Huiyan Guo Water-soluble conjugates and methods of preparation
BRPI0608281B8 (pt) 2005-04-18 2021-05-25 Amgen Res Munich Gmbh anticorpo monoclonal humano ou seu fragmento, seu uso no tratamento de doenças inflamatórias, bem como composição farmacêutica que o compreende
RU2447085C2 (ru) * 2005-05-18 2012-04-10 МорфоСис АГ Анти-gm-csf антитела и их применение
JP4736037B2 (ja) 2005-10-26 2011-07-27 株式会社イーベック ヒトｇｍ−ｃｓｆに結合するヒトのモノクローナル抗体並びにその抗原結合部分
EA200801166A1 (ru) * 2005-12-01 2008-12-30 Домантис Лимитед Форматы конкурентного доменного антитела, которые связываются с рецептором интерлейкина 1 первого типа
US7741450B2 (en) * 2006-02-08 2010-06-22 Morphotek Inc. Antibodies to GM-CSF
MX2008012291A (es) * 2006-03-27 2009-01-12 Medimmune Ltd Miembro que enlaza al receptor gm-csf.
US7741273B2 (en) * 2006-04-13 2010-06-22 Warsaw Orthopedic, Inc. Drug depot implant designs
EP2101780B1 (en) * 2006-11-21 2013-10-09 Kalobios Pharmaceuticals, Inc. Methods of treating chronic inflammatory diseases using a gm-csf antagonist
WO2008080134A2 (en) * 2006-12-22 2008-07-03 Rigel Pharmaceuticals, Inc. 4-amin0-2- (hetero) arylamino-5- (hetero) arylthiazoles useful as axl inhibitors
CN101687926A (zh) * 2007-05-23 2010-03-31 哮喘和气道Crc有限公司 中和抗体
TW200918553A (en) 2007-09-18 2009-05-01 Amgen Inc Human GM-CSF antigen binding proteins
US20090163440A1 (en) * 2007-09-26 2009-06-25 Waddell David D Ion-Channel Regulator Compositions and Methods of Using Same
WO2009062238A1 (en) 2007-11-12 2009-05-22 Crc For Asthma And Airways Ltd Epitope for neutralizing antibodies
CN104072613A (zh) 2007-11-13 2014-10-01 Evec股份有限公司 与hGM-CSF结合的单克隆抗体及包含它的药物组合物
JP2011517672A (ja) † 2008-03-24 2011-06-16 アボツト・バイオテクノロジー・リミテツド 骨損失を治療するための方法及び組成物
WO2009134805A2 (en) * 2008-04-28 2009-11-05 Kalobios Pharmaceuticals, Inc. Antibodies to granulocyte-macrophage colony-stimulating factor
CN102271705A (zh) 2008-12-22 2011-12-07 墨尔本大学 骨关节炎治疗
CA2747206C (en) † 2008-12-22 2018-04-24 The University Of Melbourne Pain treatment
US8609101B2 (en) 2009-04-23 2013-12-17 Theraclone Sciences, Inc. Granulocyte-macrophage colony-stimulating factor (GM-CSF) neutralizing antibodies

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