JP2013533745A5 - - Google Patents
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- Publication number
- JP2013533745A5 JP2013533745A5 JP2013518791A JP2013518791A JP2013533745A5 JP 2013533745 A5 JP2013533745 A5 JP 2013533745A5 JP 2013518791 A JP2013518791 A JP 2013518791A JP 2013518791 A JP2013518791 A JP 2013518791A JP 2013533745 A5 JP2013533745 A5 JP 2013533745A5
- Authority
- JP
- Japan
- Prior art keywords
- norovirus
- chimeric
- strain
- vlp
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 241001263478 Norovirus Species 0.000 claims description 74
- 108090000623 proteins and genes Proteins 0.000 claims description 46
- 102000004169 proteins and genes Human genes 0.000 claims description 36
- 210000004027 cell Anatomy 0.000 claims description 19
- 238000000034 method Methods 0.000 claims description 14
- 108020004707 nucleic acids Proteins 0.000 claims description 13
- 102000039446 nucleic acids Human genes 0.000 claims description 13
- 150000007523 nucleic acids Chemical class 0.000 claims description 13
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 10
- 230000002163 immunogen Effects 0.000 claims description 8
- 239000002245 particle Substances 0.000 claims description 7
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 4
- 229930006000 Sucrose Natural products 0.000 claims description 4
- 239000005720 sucrose Substances 0.000 claims description 4
- 230000015572 biosynthetic process Effects 0.000 claims description 3
- 239000001963 growth medium Substances 0.000 claims description 3
- 241000271566 Aves Species 0.000 claims description 2
- 241000894006 Bacteria Species 0.000 claims description 2
- 241000238631 Hexapoda Species 0.000 claims description 2
- 241000714209 Norwalk virus Species 0.000 claims description 2
- 241000509413 Snow Mountain virus Species 0.000 claims description 2
- 241000223892 Tetrahymena Species 0.000 claims description 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 2
- 238000012258 culturing Methods 0.000 claims description 2
- 210000004962 mammalian cell Anatomy 0.000 claims description 2
- 210000005253 yeast cell Anatomy 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36158110P | 2010-07-06 | 2010-07-06 | |
| US61/361,581 | 2010-07-06 | ||
| PCT/US2011/042979 WO2012006293A1 (en) | 2010-07-06 | 2011-07-05 | Norovirus derived immunogenic compositions and methods |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016000962A Division JP6351641B2 (ja) | 2010-07-06 | 2016-01-06 | ノロウイルスに由来する免疫原性組成物および方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013533745A JP2013533745A (ja) | 2013-08-29 |
| JP2013533745A5 true JP2013533745A5 (enExample) | 2014-08-14 |
Family
ID=44628871
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013518791A Pending JP2013533745A (ja) | 2010-07-06 | 2011-07-05 | ノロウイルスに由来する免疫原性組成物および方法 |
| JP2016000962A Active JP6351641B2 (ja) | 2010-07-06 | 2016-01-06 | ノロウイルスに由来する免疫原性組成物および方法 |
| JP2018030649A Withdrawn JP2018086020A (ja) | 2010-07-06 | 2018-02-23 | ノロウイルスに由来する免疫原性組成物および方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016000962A Active JP6351641B2 (ja) | 2010-07-06 | 2016-01-06 | ノロウイルスに由来する免疫原性組成物および方法 |
| JP2018030649A Withdrawn JP2018086020A (ja) | 2010-07-06 | 2018-02-23 | ノロウイルスに由来する免疫原性組成物および方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20130171185A1 (enExample) |
| EP (2) | EP3153578A1 (enExample) |
| JP (3) | JP2013533745A (enExample) |
| CN (1) | CN103154242B (enExample) |
| AU (1) | AU2011276328C1 (enExample) |
| CA (1) | CA2804501C (enExample) |
| MX (1) | MX2013000163A (enExample) |
| WO (1) | WO2012006293A1 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3243526T3 (da) | 2010-07-06 | 2020-02-17 | Glaxosmithkline Biologicals Sa | Levering af rna til at udløse flere immunsignalveje |
| CA2804492A1 (en) | 2010-07-06 | 2012-01-12 | Novartis Ag | Immunisation of large mammals with low doses of rna |
| JP2013537518A (ja) | 2010-07-06 | 2013-10-03 | ノバルティス アーゲー | ＲＮＡ送達に有利なｐＫａ値を有する脂質を含むリポソーム |
| FI4066857T3 (fi) | 2010-08-31 | 2023-03-20 | Glaxosmithkline Biologicals Sa | Pegyloituja liposomeja immunogeeniä koodaavan rna:n kuljettamiseksi |
| RU2597974C2 (ru) | 2010-10-11 | 2016-09-20 | Новартис Аг | Платформы доставки антигенов |
| WO2013006838A1 (en) * | 2011-07-06 | 2013-01-10 | Novartis Ag | Immunogenic combination compositions and uses thereof |
| AU2014204826A1 (en) * | 2013-01-10 | 2015-07-09 | Seqirus UK Limited | Influenza virus immunogenic compositions and uses thereof |
| US9975923B2 (en) * | 2013-03-15 | 2018-05-22 | The University Of North Carolina At Chapel Hill | Methods and compositions for norovirus blockade epitopes |
| EP2970395A4 (en) * | 2013-03-15 | 2017-03-29 | The University of North Carolina At Chapel Hill | Methods and compositions for norovirus blockade epitopes |
| US20160038586A1 (en) * | 2014-08-07 | 2016-02-11 | Medigen Biotechnology Corp. | Virus-like Particle Vaccines |
| EP3307239B1 (en) * | 2015-06-12 | 2020-09-16 | Vaxart, Inc. | Formulations for small intestinal delivery of rsv and norovirus antigens |
| CN107034198B (zh) | 2015-07-15 | 2021-03-09 | 长春百克生物科技股份公司 | 一种嵌合诺如病毒p颗粒及其制备和应用 |
| WO2017160124A2 (ko) * | 2016-03-18 | 2017-09-21 | 연세대학교 산학협력단 | 노로 바이러스 백신을 생산하기 위한 재조합 발현 벡터 |
| KR101914779B1 (ko) | 2016-03-18 | 2018-11-02 | (주)인테라 | 노로 바이러스 백신을 생산하기 위한 재조합 발현 벡터 |
| EP4477662A3 (en) | 2016-05-04 | 2025-03-19 | CureVac SE | Nucleic acid molecules and uses thereof |
| WO2017214557A1 (en) | 2016-06-10 | 2017-12-14 | Counsyl, Inc. | Nucleic acid sequencing adapters and uses thereof |
| CA3037366A1 (en) | 2016-09-29 | 2018-04-05 | Myriad Women's Health, Inc. | Noninvasive prenatal screening using dynamic iterative depth optimization |
| US10968447B2 (en) | 2017-01-31 | 2021-04-06 | Myriad Women's Health, Inc. | Methods and compositions for enrichment of target polynucleotides |
| WO2018144217A1 (en) | 2017-01-31 | 2018-08-09 | Counsyl, Inc. | Methods and compositions for enrichment of target polynucleotides |
| WO2018170603A1 (en) | 2017-03-23 | 2018-09-27 | Medicago Inc. | Norovirus fusion proteins and vlps comprising norovirus fusion proteins |
| US11232850B2 (en) | 2017-03-24 | 2022-01-25 | Myriad Genetics, Inc. | Copy number variant caller |
| WO2018182983A1 (en) * | 2017-03-28 | 2018-10-04 | Children's Hospital Medical Center | Norovirus s particle based vaccines and methods of making and using same |
| EP3717648A4 (en) | 2017-11-30 | 2021-12-01 | Medicago Inc. | MODIFIED NOROVIRUS VP1 PROTEINS AND VLPS WITH MODIFIED NOROVIRUS VP1 PROTEINS |
| JP6713013B2 (ja) * | 2018-03-06 | 2020-06-24 | 株式会社イーダブルニュートリション・ジャパン | 貝類のノロウイルス不活化方法 |
| JP7429684B6 (ja) * | 2018-07-13 | 2024-03-15 | メディカゴ インコーポレイテッド | 改変ノロウイルスｖｐ１タンパク質および改変ノロウイルスｖｐ１タンパク質を含むｖｌｐ |
| WO2020182860A1 (en) * | 2019-03-12 | 2020-09-17 | Icon Genetics Gmbh | Norovirus-like particles with improved stability |
| BR112022013537A2 (pt) * | 2020-01-08 | 2022-11-22 | Bharat Biotech Int Ltd | Composições de vacina viral e métodos de preparações das mesmas |
| CN114316033A (zh) * | 2020-09-29 | 2022-04-12 | 香港理工大学深圳研究院 | 一种特异性识别诺如病毒的单克隆抗体及制备方法与应用 |
| CN115161343B (zh) * | 2021-04-01 | 2024-06-04 | 苏州相奕生物技术有限公司 | 一种重组腺病毒表达载体及以其制备的多价诺如病毒疫苗 |
| EP4422681A4 (en) * | 2021-10-27 | 2025-11-19 | Univ Pennsylvania | VACCINE AGAINST A NOROVIRUS AND METHODS OF USE |
| KR20240145520A (ko) | 2022-03-18 | 2024-10-07 | 덴카 주식회사 | 링커에 의해 연결된 캡시드 단백질을 포함하는 바이러스 유사입자 |
| WO2024144272A1 (ko) * | 2022-12-27 | 2024-07-04 | (주)한국바이오셀프 | 노로바이러스 gii mrna를 포함하는 백신 조성물 |
| WO2024144262A1 (ko) * | 2022-12-27 | 2024-07-04 | (주)한국바이오셀프 | 노로바이러스 gi mrna를 포함하는 백신 조성물 |
| CN118126202B (zh) * | 2024-05-07 | 2024-07-30 | 上海瑞宙生物科技有限公司 | 一种诺如病毒类病毒颗粒及其应用 |
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-
2011
- 2011-07-05 AU AU2011276328A patent/AU2011276328C1/en active Active
- 2011-07-05 US US13/808,157 patent/US20130171185A1/en not_active Abandoned
- 2011-07-05 WO PCT/US2011/042979 patent/WO2012006293A1/en not_active Ceased
- 2011-07-05 MX MX2013000163A patent/MX2013000163A/es unknown
- 2011-07-05 CA CA2804501A patent/CA2804501C/en active Active
- 2011-07-05 EP EP16199523.8A patent/EP3153578A1/en not_active Ceased
- 2011-07-05 JP JP2013518791A patent/JP2013533745A/ja active Pending
- 2011-07-05 CN CN201180042647.5A patent/CN103154242B/zh active Active
- 2011-07-05 EP EP11735734.3A patent/EP2591097A1/en not_active Withdrawn
-
2015
- 2015-11-19 US US14/946,324 patent/US10065994B2/en active Active
-
2016
- 2016-01-06 JP JP2016000962A patent/JP6351641B2/ja active Active
-
2018
- 2018-02-23 JP JP2018030649A patent/JP2018086020A/ja not_active Withdrawn
- 2018-08-02 US US16/053,399 patent/US10287324B2/en active Active
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