JP2023024998A5 - - Google Patents
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- Publication number
- JP2023024998A5 JP2023024998A5 JP2022177946A JP2022177946A JP2023024998A5 JP 2023024998 A5 JP2023024998 A5 JP 2023024998A5 JP 2022177946 A JP2022177946 A JP 2022177946A JP 2022177946 A JP2022177946 A JP 2022177946A JP 2023024998 A5 JP2023024998 A5 JP 2023024998A5
- Authority
- JP
- Japan
- Prior art keywords
- modified
- protein
- influenza
- virus
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 101710154606 Hemagglutinin Proteins 0.000 claims 36
- 101710093908 Outer capsid protein VP4 Proteins 0.000 claims 36
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 claims 36
- 101710176177 Protein A56 Proteins 0.000 claims 36
- 206010022000 influenza Diseases 0.000 claims 18
- 241000712461 unidentified influenza virus Species 0.000 claims 17
- 102000039446 nucleic acids Human genes 0.000 claims 12
- 108020004707 nucleic acids Proteins 0.000 claims 12
- 150000007523 nucleic acids Chemical class 0.000 claims 12
- 239000008194 pharmaceutical composition Substances 0.000 claims 10
- 239000000185 hemagglutinin Substances 0.000 claims 6
- 102000040430 polynucleotide Human genes 0.000 claims 6
- 108091033319 polynucleotide Proteins 0.000 claims 6
- 239000002157 polynucleotide Substances 0.000 claims 6
- 108091005804 Peptidases Proteins 0.000 claims 5
- 239000004365 Protease Substances 0.000 claims 5
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 4
- 241000700605 Viruses Species 0.000 claims 4
- 230000002163 immunogen Effects 0.000 claims 4
- 230000003472 neutralizing effect Effects 0.000 claims 3
- 241000723792 Tobacco etch virus Species 0.000 claims 2
- 238000003776 cleavage reaction Methods 0.000 claims 2
- 239000001963 growth medium Substances 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 230000002401 inhibitory effect Effects 0.000 claims 2
- 239000002245 particle Substances 0.000 claims 2
- 230000007017 scission Effects 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 102000035195 Peptidases Human genes 0.000 claims 1
- 108010076818 TEV protease Proteins 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 230000002238 attenuated effect Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 238000011321 prophylaxis Methods 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662290894P | 2016-02-03 | 2016-02-03 | |
| US62/290,894 | 2016-02-03 | ||
| JP2018540112A JP7560938B2 (ja) | 2016-02-03 | 2017-02-02 | 異種エピトープ及び／又は改変された成熟切断部位を有するインフルエンザヘマグルチニンの組成物 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018540112A Division JP7560938B2 (ja) | 2016-02-03 | 2017-02-02 | 異種エピトープ及び／又は改変された成熟切断部位を有するインフルエンザヘマグルチニンの組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023024998A JP2023024998A (ja) | 2023-02-21 |
| JP2023024998A5 true JP2023024998A5 (enExample) | 2023-06-01 |
| JP7577101B2 JP7577101B2 (ja) | 2024-11-01 |
Family
ID=63036971
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018540112A Active JP7560938B2 (ja) | 2016-02-03 | 2017-02-02 | 異種エピトープ及び／又は改変された成熟切断部位を有するインフルエンザヘマグルチニンの組成物 |
| JP2022177946A Active JP7577101B2 (ja) | 2016-02-03 | 2022-11-07 | 異種エピトープ及び／又は改変された成熟切断部位を有するインフルエンザヘマグルチニンの組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018540112A Active JP7560938B2 (ja) | 2016-02-03 | 2017-02-02 | 異種エピトープ及び／又は改変された成熟切断部位を有するインフルエンザヘマグルチニンの組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US10291197B2 (enExample) |
| EP (1) | EP3411712B1 (enExample) |
| JP (2) | JP7560938B2 (enExample) |
| KR (1) | KR102748840B1 (enExample) |
| CN (2) | CN109073639B (enExample) |
| AU (2) | AU2017215345B2 (enExample) |
| CA (1) | CA3012703A1 (enExample) |
| MX (2) | MX380837B (enExample) |
| RU (2) | RU2022108149A (enExample) |
| SG (2) | SG10202108573TA (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102465833B1 (ko) | 2017-11-28 | 2022-11-11 | 삼성전자주식회사 | 무선 통신 시스템에서 전력 설정 방법 및 이를 위한 장치 |
| KR102370100B1 (ko) * | 2019-02-15 | 2022-03-07 | 아이디바이오 주식회사 | 이종 인플루엔자 a 바이러스에 대한 면역/치료반응을 형성하는 신규한 재조합 인플루엔자 바이러스 및 이를 포함하는 유전자 전달체 및 치료백신 |
| CN117534737B (zh) * | 2022-07-15 | 2024-09-06 | 中山大学·深圳 | 一种季节性甲型流感通用Mosaic重组抗原及其疫苗和应用 |
| CN116874607B (zh) * | 2023-06-09 | 2024-12-10 | 山西高等创新研究院 | 一种h9亚型禽流感重组嵌合疫苗及其制备方法 |
| CN118978590B (zh) * | 2024-10-12 | 2025-01-21 | 北京溯本源和生物科技有限公司 | 一种利用重组流感病毒免疫小鼠制备杂交瘤单抗的方法及应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL103928A0 (en) * | 1991-12-11 | 1993-04-04 | American Home Prod | Expression of specific immunogens using viral antigens |
| EP0974660A1 (en) | 1998-06-19 | 2000-01-26 | Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) | Newcastle disease virus infectious clones, vaccines and diagnostic assays |
| DE10248301A1 (de) * | 2002-10-16 | 2004-04-29 | Philipps-Universität Marburg | Herstellung eines Lebend-Impfstoffes gegen Influenza-Viren |
| DE10249294A1 (de) | 2002-10-22 | 2004-05-13 | Rohmax Additives Gmbh | Stabile Polymerdispersionen und Verfahren zur Herstellung |
| MX2010001284A (es) * | 2007-08-02 | 2010-08-31 | Biondvax Pharmaceuticals Ltd | Vacunas contra la influenza con multiepitope multimerico. |
| AU2009270399A1 (en) | 2008-07-18 | 2010-01-21 | Id Biomedical Corporation Of Quebec | Chimeric respiratory syncytial virus polypeptide antigens |
| CN102165062B (zh) | 2008-07-18 | 2017-09-08 | 麦迪卡格公司 | 新的流感病毒免疫表位 |
| JP5871796B2 (ja) * | 2009-06-24 | 2016-03-01 | メディカゴ インコーポレイテッド | ヘマグルチニンを含むキメラインフルエンザウイルス様粒子 |
| CN101857872A (zh) * | 2010-04-06 | 2010-10-13 | 浙江省医学科学院 | 甲型流感病毒抗原决定区更换方法 |
| AU2011360572B2 (en) * | 2011-02-22 | 2017-03-02 | Biondvax Pharmaceuticals Ltd. | Multimeric multiepitope polypeptides in improved seasonal and pandemic influenza vaccines |
| KR20140068205A (ko) * | 2011-09-20 | 2014-06-05 | 마운트 시나이 스쿨 오브 메디슨 | 인플루엔자 바이러스 백신 및 이의 용도 |
| WO2015020913A2 (en) * | 2013-08-03 | 2015-02-12 | Marshall Christopher Patrick | Influenza hemagglutinin proteins and methods of thereof |
| WO2016205347A1 (en) * | 2015-06-16 | 2016-12-22 | Icahn School Of Medicine At Mount Sinai | Influenza virus vaccines and uses thereof |
-
2017
- 2017-02-02 EP EP17748171.0A patent/EP3411712B1/en active Active
- 2017-02-02 CA CA3012703A patent/CA3012703A1/en active Pending
- 2017-02-02 KR KR1020187025483A patent/KR102748840B1/ko active Active
- 2017-02-02 CN CN201780018856.3A patent/CN109073639B/zh active Active
- 2017-02-02 CN CN202210283751.3A patent/CN114634916B/zh active Active
- 2017-02-02 JP JP2018540112A patent/JP7560938B2/ja active Active
- 2017-02-02 RU RU2022108149A patent/RU2022108149A/ru unknown
- 2017-02-02 US US15/556,555 patent/US10291197B2/en active Active
- 2017-02-02 RU RU2018131243A patent/RU2769406C2/ru active
- 2017-02-02 AU AU2017215345A patent/AU2017215345B2/en active Active
- 2017-02-02 MX MX2018009395A patent/MX380837B/es unknown
- 2017-02-02 SG SG10202108573TA patent/SG10202108573TA/en unknown
- 2017-02-02 SG SG11201806567WA patent/SG11201806567WA/en unknown
-
2018
- 2018-08-01 MX MX2021003392A patent/MX2021003392A/es unknown
-
2019
- 2019-05-13 US US16/410,998 patent/US11206005B2/en active Active
-
2021
- 2021-12-20 US US17/556,816 patent/US11979133B2/en active Active
-
2022
- 2022-11-07 JP JP2022177946A patent/JP7577101B2/ja active Active
-
2024
- 2024-01-19 AU AU2024200382A patent/AU2024200382B2/en active Active
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