JP2019506168A5 - - Google Patents
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- Publication number
- JP2019506168A5 JP2019506168A5 JP2018540112A JP2018540112A JP2019506168A5 JP 2019506168 A5 JP2019506168 A5 JP 2019506168A5 JP 2018540112 A JP2018540112 A JP 2018540112A JP 2018540112 A JP2018540112 A JP 2018540112A JP 2019506168 A5 JP2019506168 A5 JP 2019506168A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- virus
- modified
- influenza
- epitope
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 101710154606 Hemagglutinin Proteins 0.000 claims 22
- 101710093908 Outer capsid protein VP4 Proteins 0.000 claims 22
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 claims 22
- 101710176177 Protein A56 Proteins 0.000 claims 22
- 241000700605 Viruses Species 0.000 claims 10
- 241000712461 unidentified influenza virus Species 0.000 claims 10
- 229960005486 vaccine Drugs 0.000 claims 10
- 206010022000 influenza Diseases 0.000 claims 9
- 230000002163 immunogen Effects 0.000 claims 8
- 102000039446 nucleic acids Human genes 0.000 claims 7
- 108020004707 nucleic acids Proteins 0.000 claims 7
- 150000007523 nucleic acids Chemical class 0.000 claims 7
- 108091005804 Peptidases Proteins 0.000 claims 5
- 239000004365 Protease Substances 0.000 claims 5
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 5
- 241000723792 Tobacco etch virus Species 0.000 claims 5
- 238000003776 cleavage reaction Methods 0.000 claims 5
- 230000007017 scission Effects 0.000 claims 5
- 239000000185 hemagglutinin Substances 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 239000000427 antigen Substances 0.000 claims 3
- 102000036639 antigens Human genes 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Natural products NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 2
- 239000004471 Glycine Substances 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 125000003630 glycyl group Chemical group [H]N([H])C([H])([H])C(*)=O 0.000 claims 2
- 239000002245 particle Substances 0.000 claims 2
- 239000004475 Arginine Substances 0.000 claims 1
- 241001500351 Influenzavirus A Species 0.000 claims 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 1
- 125000000637 arginyl group Chemical group N[C@@H](CCCNC(N)=N)C(=O)* 0.000 claims 1
- 230000002238 attenuated effect Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022177946A JP7577101B2 (ja) | 2016-02-03 | 2022-11-07 | 異種エピトープ及び／又は改変された成熟切断部位を有するインフルエンザヘマグルチニンの組成物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662290894P | 2016-02-03 | 2016-02-03 | |
| US62/290,894 | 2016-02-03 | ||
| PCT/US2017/016251 WO2017136575A1 (en) | 2016-02-03 | 2017-02-02 | Compositions of influenza hemagglutinin with heterologous epitopes and/or altered maturation cleavage sites |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022177946A Division JP7577101B2 (ja) | 2016-02-03 | 2022-11-07 | 異種エピトープ及び／又は改変された成熟切断部位を有するインフルエンザヘマグルチニンの組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019506168A JP2019506168A (ja) | 2019-03-07 |
| JP2019506168A5 true JP2019506168A5 (enExample) | 2020-06-25 |
| JP7560938B2 JP7560938B2 (ja) | 2024-10-03 |
Family
ID=63036971
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018540112A Active JP7560938B2 (ja) | 2016-02-03 | 2017-02-02 | 異種エピトープ及び／又は改変された成熟切断部位を有するインフルエンザヘマグルチニンの組成物 |
| JP2022177946A Active JP7577101B2 (ja) | 2016-02-03 | 2022-11-07 | 異種エピトープ及び／又は改変された成熟切断部位を有するインフルエンザヘマグルチニンの組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022177946A Active JP7577101B2 (ja) | 2016-02-03 | 2022-11-07 | 異種エピトープ及び／又は改変された成熟切断部位を有するインフルエンザヘマグルチニンの組成物 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US10291197B2 (enExample) |
| EP (1) | EP3411712B1 (enExample) |
| JP (2) | JP7560938B2 (enExample) |
| KR (1) | KR102748840B1 (enExample) |
| CN (2) | CN114634916B (enExample) |
| AU (2) | AU2017215345B2 (enExample) |
| BR (1) | BR112018015765A2 (enExample) |
| CA (1) | CA3012703A1 (enExample) |
| MX (2) | MX380837B (enExample) |
| RU (2) | RU2769406C2 (enExample) |
| SG (2) | SG10202108573TA (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102465833B1 (ko) | 2017-11-28 | 2022-11-11 | 삼성전자주식회사 | 무선 통신 시스템에서 전력 설정 방법 및 이를 위한 장치 |
| KR102370100B1 (ko) * | 2019-02-15 | 2022-03-07 | 아이디바이오 주식회사 | 이종 인플루엔자 a 바이러스에 대한 면역/치료반응을 형성하는 신규한 재조합 인플루엔자 바이러스 및 이를 포함하는 유전자 전달체 및 치료백신 |
| CN117534737B (zh) * | 2022-07-15 | 2024-09-06 | 中山大学·深圳 | 一种季节性甲型流感通用Mosaic重组抗原及其疫苗和应用 |
| CN116874607B (zh) * | 2023-06-09 | 2024-12-10 | 山西高等创新研究院 | 一种h9亚型禽流感重组嵌合疫苗及其制备方法 |
| CN118978590B (zh) * | 2024-10-12 | 2025-01-21 | 北京溯本源和生物科技有限公司 | 一种利用重组流感病毒免疫小鼠制备杂交瘤单抗的方法及应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2084180A1 (en) * | 1991-12-11 | 1993-06-12 | Paul P. Hung | Expression of specific immunogens using viral antigens |
| EP0974660A1 (en) | 1998-06-19 | 2000-01-26 | Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) | Newcastle disease virus infectious clones, vaccines and diagnostic assays |
| DE10248301A1 (de) * | 2002-10-16 | 2004-04-29 | Philipps-Universität Marburg | Herstellung eines Lebend-Impfstoffes gegen Influenza-Viren |
| DE10249294A1 (de) | 2002-10-22 | 2004-05-13 | Rohmax Additives Gmbh | Stabile Polymerdispersionen und Verfahren zur Herstellung |
| ES2539818T3 (es) * | 2007-08-02 | 2015-07-06 | Biondvax Pharmaceuticals Ltd. | Vacunas contra la gripe multiepitópicas multiméricas |
| AU2009270404B2 (en) * | 2008-07-18 | 2015-01-29 | Medicago Inc. | New influenza virus immunizing epitope |
| KR20110045008A (ko) | 2008-07-18 | 2011-05-03 | 아이디 바이오메디컬 코포레이션 오브 퀘벡 | 키메라 호흡기 세포융합 바이러스 폴리펩티드 항원 |
| CA2762042C (en) * | 2009-06-24 | 2012-11-20 | Medicago Inc. | Chimeric influenza virus-like particles comprising hemagglutinin |
| CN101857872A (zh) * | 2010-04-06 | 2010-10-13 | 浙江省医学科学院 | 甲型流感病毒抗原决定区更换方法 |
| WO2012114323A1 (en) * | 2011-02-22 | 2012-08-30 | Biondvax Pharmaceuticals Ltd. | Multimeric multiepitope polypeptides in improved seasonal and pandemic influenza vaccines |
| IN2014CN02114A (enExample) * | 2011-09-20 | 2015-05-29 | Sinai School Medicine | |
| EP3027640B1 (en) * | 2013-08-03 | 2018-03-07 | Avatar Medical, LLC | Influenza hemagglutinin proteins and methods of use thereof |
| WO2016205347A1 (en) * | 2015-06-16 | 2016-12-22 | Icahn School Of Medicine At Mount Sinai | Influenza virus vaccines and uses thereof |
-
2017
- 2017-02-02 US US15/556,555 patent/US10291197B2/en active Active
- 2017-02-02 RU RU2018131243A patent/RU2769406C2/ru active
- 2017-02-02 SG SG10202108573TA patent/SG10202108573TA/en unknown
- 2017-02-02 CN CN202210283751.3A patent/CN114634916B/zh active Active
- 2017-02-02 AU AU2017215345A patent/AU2017215345B2/en active Active
- 2017-02-02 EP EP17748171.0A patent/EP3411712B1/en active Active
- 2017-02-02 CA CA3012703A patent/CA3012703A1/en active Pending
- 2017-02-02 RU RU2022108149A patent/RU2022108149A/ru unknown
- 2017-02-02 KR KR1020187025483A patent/KR102748840B1/ko active Active
- 2017-02-02 SG SG11201806567WA patent/SG11201806567WA/en unknown
- 2017-02-02 JP JP2018540112A patent/JP7560938B2/ja active Active
- 2017-02-02 CN CN201780018856.3A patent/CN109073639B/zh active Active
- 2017-02-02 MX MX2018009395A patent/MX380837B/es unknown
- 2017-02-02 BR BR112018015765-1A patent/BR112018015765A2/pt active IP Right Grant
-
2018
- 2018-08-01 MX MX2021003392A patent/MX2021003392A/es unknown
-
2019
- 2019-05-13 US US16/410,998 patent/US11206005B2/en active Active
-
2021
- 2021-12-20 US US17/556,816 patent/US11979133B2/en active Active
-
2022
- 2022-11-07 JP JP2022177946A patent/JP7577101B2/ja active Active
-
2024
- 2024-01-19 AU AU2024200382A patent/AU2024200382A1/en active Pending
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