JP2017530124A5 - - Google Patents
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- Publication number
- JP2017530124A5 JP2017530124A5 JP2017516077A JP2017516077A JP2017530124A5 JP 2017530124 A5 JP2017530124 A5 JP 2017530124A5 JP 2017516077 A JP2017516077 A JP 2017516077A JP 2017516077 A JP2017516077 A JP 2017516077A JP 2017530124 A5 JP2017530124 A5 JP 2017530124A5
- Authority
- JP
- Japan
- Prior art keywords
- fmdv
- composition
- vaccine
- antigen
- viral vector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000710198 Foot-and-mouth disease virus Species 0.000 claims 27
- 239000000203 mixture Substances 0.000 claims 17
- 239000000427 antigen Substances 0.000 claims 16
- 102000036639 antigens Human genes 0.000 claims 16
- 108091007433 antigens Proteins 0.000 claims 16
- 229960005486 vaccine Drugs 0.000 claims 13
- 239000013603 viral vector Substances 0.000 claims 10
- 102000040430 polynucleotide Human genes 0.000 claims 8
- 108091033319 polynucleotide Proteins 0.000 claims 8
- 239000002157 polynucleotide Substances 0.000 claims 8
- 238000000034 method Methods 0.000 claims 7
- 229920001184 polypeptide Polymers 0.000 claims 7
- 102000004196 processed proteins & peptides Human genes 0.000 claims 7
- 108090000765 processed proteins & peptides Proteins 0.000 claims 7
- 241000238631 Hexapoda Species 0.000 claims 3
- 238000001727 in vivo Methods 0.000 claims 3
- 239000013612 plasmid Substances 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 206010061818 Disease progression Diseases 0.000 claims 2
- 235000001014 amino acid Nutrition 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 235000018417 cysteine Nutrition 0.000 claims 2
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims 2
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 claims 2
- 230000005750 disease progression Effects 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 238000006467 substitution reaction Methods 0.000 claims 2
- 241000701161 unidentified adenovirus Species 0.000 claims 2
- 241001465754 Metazoa Species 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000003053 immunization Effects 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 238000005215 recombination Methods 0.000 claims 1
- 230000006798 recombination Effects 0.000 claims 1
- 241000701447 unidentified baculovirus Species 0.000 claims 1
- 239000013598 vector Substances 0.000 claims 1
- 239000003981 vehicle Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462054073P | 2014-09-23 | 2014-09-23 | |
| US62/054,073 | 2014-09-23 | ||
| PCT/US2015/051755 WO2016049209A1 (en) | 2014-09-23 | 2015-09-23 | Fmdv recombinant vaccines and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017530124A JP2017530124A (ja) | 2017-10-12 |
| JP2017530124A5 true JP2017530124A5 (enExample) | 2018-11-01 |
| JP6931327B2 JP6931327B2 (ja) | 2021-09-01 |
Family
ID=54256845
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017516077A Active JP6931327B2 (ja) | 2014-09-23 | 2015-09-23 | Ｆｍｄｖ組換えワクチンおよびその使用 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US10010605B2 (enExample) |
| EP (2) | EP4778534A2 (enExample) |
| JP (1) | JP6931327B2 (enExample) |
| KR (1) | KR102526219B1 (enExample) |
| CN (1) | CN107073100B (enExample) |
| AP (1) | AP2017009834A0 (enExample) |
| AR (1) | AR102006A1 (enExample) |
| AU (2) | AU2015320673B2 (enExample) |
| CA (1) | CA2962225A1 (enExample) |
| DK (1) | DK3197486T3 (enExample) |
| ES (1) | ES3074144T3 (enExample) |
| JO (1) | JO3600B1 (enExample) |
| MA (1) | MA40151B2 (enExample) |
| MX (1) | MX388708B (enExample) |
| PY (1) | PY1548374A (enExample) |
| RU (1) | RU2745373C2 (enExample) |
| TW (1) | TWI733653B (enExample) |
| WO (1) | WO2016049209A1 (enExample) |
| ZA (1) | ZA201701851B (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3347044B1 (en) * | 2015-09-10 | 2023-04-19 | Academia Sinica | Bird flu vaccine combination comprising virus-like particles and novel adjuvants |
| JP6797206B2 (ja) | 2015-11-23 | 2020-12-09 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | Ｆｍｄｖ及びｅ２融合タンパク質並びにその使用 |
| TWI760322B (zh) | 2016-01-29 | 2022-04-11 | 美商百靈佳殷格翰動物保健美國有限公司 | 重組腺病毒載體裝載之fmdv疫苗及其用途 |
| US10172933B2 (en) * | 2016-10-31 | 2019-01-08 | The United States Of America, As Represented By The Secretary Of Agriculture | Mosaic vaccines for serotype a foot-and-mouth disease virus |
| JP7083362B2 (ja) * | 2017-07-12 | 2022-06-10 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | セネカウイルスａ免疫原性組成物およびその方法 |
| CN108103034B (zh) * | 2017-12-15 | 2022-06-24 | 云南农业大学动物医学院 | 同时表达A型、O型和Asia-1型口蹄疫病毒VP1基因重组腺病毒、构建方法及应用 |
| CN108530522B (zh) * | 2018-03-14 | 2021-09-17 | 中华人民共和国汕头海关 | 一种重组的OmpK多表位多肽、构建方法及其应用 |
| CN110467654B (zh) * | 2018-05-11 | 2022-08-09 | 普莱柯生物工程股份有限公司 | 口蹄疫病毒样颗粒抗原、其制备的疫苗组合物及其制备方法和应用 |
| CN111233984B (zh) * | 2018-11-29 | 2022-08-12 | 普莱柯生物工程股份有限公司 | 一种o型口蹄疫病毒样颗粒抗原、及其疫苗组合物、制备方法和应用 |
| US12226472B2 (en) * | 2019-01-15 | 2025-02-18 | Pulike Biological Engineering, Inc. | Foot-and-mouth disease virus-like particle antigen, and vaccine composition, preparation method, and application thereof |
| WO2020263062A1 (ko) * | 2019-06-28 | 2020-12-30 | (주)플럼라인생명과학 | 구제역 바이러스 백신 조성물 |
| JP2023549461A (ja) * | 2020-10-22 | 2023-11-27 | インターベット インターナショナル ベー． フェー． | バキュロウイルス発現ベクター |
| CN116685687A (zh) * | 2020-10-22 | 2023-09-01 | 英特维特国际股份有限公司 | 杆状病毒表达载体 |
| US12453767B2 (en) | 2021-08-18 | 2025-10-28 | The United States Of America, As Represented By The Secretary Of Agriculture | Development of mosaic vaccines against foot and mouth disease virus serotype O |
| IL310903A (en) * | 2021-08-20 | 2024-04-01 | Intervet Int Bv | Method of producing a foot and mouth disease virus virus-like particle |
| EP4387665A1 (en) * | 2021-08-20 | 2024-06-26 | The Pirbright Institute | Fmdv virus-like particle with double stabilizing mutation |
| IL310908A (en) * | 2021-08-20 | 2024-04-01 | Intervet Int Bv | A virus-like FMDV particle with a stabilizing mutation |
| EP4387661A1 (en) * | 2021-08-20 | 2024-06-26 | Intervet International B.V. | Method of producing a foot and mouth disease virus virus-like particle |
| KR102513632B1 (ko) * | 2021-11-30 | 2023-03-28 | 주식회사 왓슨알앤디 | 구제역 바이러스 유사 입자를 생산하기 위한 백신 플랫폼 |
| US12036318B2 (en) * | 2022-02-16 | 2024-07-16 | Chemical & Schutz High Performance Lubricants, S.A. De C.V. | Self-emulsionable mineral oil as a vehicle in vaccines for poultry |
| EP4628096A1 (en) | 2022-11-23 | 2025-10-08 | Optipharm Co., Ltd. | Recombinant expression vector for preparing foot-and-mouth disease virus-like particles or nanoparticles, and vaccine composition using same |
| WO2024112115A1 (ko) * | 2022-11-23 | 2024-05-30 | 주식회사 옵티팜 | 구제역 바이러스 유사 입자 또는 나노입자 생산을 위한 재조합 발현 벡터 및 이를 이용한 백신 조성물 |
| CN117210501B (zh) * | 2023-09-13 | 2024-06-07 | 中国农业科学院兰州兽医研究所 | 口蹄疫病毒2b蛋白免疫抑制位点突变的重组口蹄疫病毒株的构建 |
| CN117304277B (zh) * | 2023-09-26 | 2024-03-08 | 中国农业科学院兰州兽医研究所 | 一种o型口蹄疫病毒vp4蛋白t细胞表位多肽及其应用 |
| US20250134984A1 (en) * | 2023-10-26 | 2025-05-01 | The United States Of America, As Represented By The Secretary Of Agriculture | Development of mosaic vaccines against foot and mouth disease virus serotype asia |
| WO2026162694A1 (en) * | 2025-02-01 | 2026-08-06 | The Chancellor, Masters And Scholars Of The University Of Oxford | Fmdv virus-like particle with stabilizing mutations |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2909462A (en) | 1955-12-08 | 1959-10-20 | Bristol Myers Co | Acrylic acid polymer laxative compositions |
| US5505941A (en) | 1981-12-24 | 1996-04-09 | Health Research, Inc. | Recombinant avipox virus and method to induce an immune response |
| CA1247080A (en) | 1983-03-08 | 1988-12-20 | Commonwealth Serum Laboratories Commission | Antigenically active amino acid sequences |
| EP0173552B1 (en) | 1984-08-24 | 1991-10-09 | The Upjohn Company | Recombinant dna compounds and the expression of polypeptides such as tpa |
| US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
| US4963481A (en) | 1985-12-18 | 1990-10-16 | Genetics Institute Inc | Promoter system |
| US4968615A (en) | 1985-12-18 | 1990-11-06 | Ciba-Geigy Corporation | Deoxyribonucleic acid segment from a virus |
| GB2197321B (en) | 1986-09-12 | 1990-10-03 | Genentech Inc | Method and vectors for obtaining continuous production of heterologous protein in a eukaryotic host cell line |
| GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
| DE3743138A1 (de) | 1987-12-18 | 1989-09-14 | Mayr Christian Gmbh & Co Kg | Schleifringlose, elektromagnetische ueberlastkupplung |
| ZA915593B (en) | 1990-07-24 | 1993-03-31 | Novagene Inc | Herpesvirus-based viral vector which expresses a foot and mounth disease virus epitope on the surface of virus-infected cells and on the surface of virus particles,and vaccine against foot and mounth disease containing the same |
| JPH11504631A (ja) | 1995-04-25 | 1999-04-27 | バイカル インコーポレイテッド | Ｄｎａ／脂質複合体の単一バイアル製剤 |
| US5846946A (en) | 1996-06-14 | 1998-12-08 | Pasteur Merieux Serums Et Vaccins | Compositions and methods for administering Borrelia DNA |
| FR2751226B1 (fr) | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique contre les pathologies du cheval |
| FR2751228B1 (fr) | 1996-07-19 | 1998-11-20 | Rhone Merieux | Vaccin polynucleotidique bovin pour voie intradermique |
| FR2751227B1 (fr) | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique contre les pathologies canines, notamment les pathologies respiratoires et digestives |
| FR2751229B1 (fr) | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique notamment contre la pathologie respiratoire des bovins |
| FR2751225B1 (fr) | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique aviaire |
| FR2751224B1 (fr) | 1996-07-19 | 1998-11-20 | Rhone Merieux | Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs |
| WO1998016247A1 (en) | 1996-10-11 | 1998-04-23 | The Regents Of The University Of California | Immunostimulatory polynucleotide/immunomodulatory molecule conjugates |
| CA2294793A1 (fr) | 1997-06-30 | 1999-01-14 | Rhone-Poulenc Rorer S.A. | Amelioration du transfert d'acide nucleique dans le muscle strie et combinaison permettant la mise en oeuvre du procede |
| FR2778858B1 (fr) | 1998-05-20 | 2000-06-16 | Oreal | Emulsion e/h/e stable et son utilisation comme composition cosmetique et/ou dermatologique |
| FR2801607B1 (fr) | 1999-11-26 | 2001-12-28 | Merial Sas | Pneumovirus du canard et vaccins correspondants |
| US6852705B2 (en) | 2000-01-21 | 2005-02-08 | Merial | DNA vaccines for farm animals, in particular bovines and porcines |
| FR2810888B1 (fr) * | 2000-06-29 | 2004-07-30 | Merial Sas | Vaccin contre la fievre aphteuse |
| PL1651265T3 (pl) | 2003-07-24 | 2008-10-31 | Merial Ltd | Formulacje szczepionek zawierających emulsję olej w wodzie |
| US7527960B2 (en) | 2004-06-25 | 2009-05-05 | Merial Limited | Avipox recombinants expressing foot and mouth disease virus genes |
| US7691368B2 (en) | 2005-04-15 | 2010-04-06 | Merial Limited | Vaccine formulations |
| WO2007059461A2 (en) | 2005-11-10 | 2007-05-24 | Genvec, Inc. | Adenoviral vector-based foot-and-mouth disease vaccine |
| US20100285056A1 (en) * | 2008-01-09 | 2010-11-11 | Konkuk University Industrial Cooperation Corp. | Baculovirus-Based Vaccines |
| CN101270155B (zh) * | 2008-05-06 | 2011-04-27 | 中国农业科学院兰州兽医研究所 | 通过耐酸性改造在昆虫中组装口蹄疫病毒空衣壳的方法 |
| GB0810710D0 (en) * | 2008-06-11 | 2008-07-16 | Animal Health Inst | Vaccine |
| DK2475384T3 (en) | 2009-09-10 | 2016-10-24 | Merial Inc | NEW VACCINE FORMULATIONS COMPREHENSIVE saponin-CONTAINING ADJUVANTS |
| WO2011112945A2 (en) * | 2010-03-12 | 2011-09-15 | Merial Limited | Foot and mouth disease virus recombinant vaccines and uses thereof |
| RS56748B1 (sr) * | 2011-05-13 | 2018-03-30 | Glaxosmithkline Biologicals Sa | Pre-fuzioni rsv f antigeni |
| GB201111183D0 (en) * | 2011-06-30 | 2011-08-17 | Animal Health Inst | Peptide |
| US20150183835A1 (en) * | 2012-06-18 | 2015-07-02 | Novartis Ag | Stabilized gp120 |
| US9738689B2 (en) * | 2013-03-13 | 2017-08-22 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Prefusion RSV F proteins and their use |
-
2015
- 2015-09-23 US US14/863,181 patent/US10010605B2/en active Active
- 2015-09-23 MX MX2017003712A patent/MX388708B/es unknown
- 2015-09-23 MA MA40151A patent/MA40151B2/fr unknown
- 2015-09-23 ES ES15775553T patent/ES3074144T3/es active Active
- 2015-09-23 JP JP2017516077A patent/JP6931327B2/ja active Active
- 2015-09-23 EP EP26172334.0A patent/EP4778534A2/en active Pending
- 2015-09-23 WO PCT/US2015/051755 patent/WO2016049209A1/en not_active Ceased
- 2015-09-23 AR ARP150103061A patent/AR102006A1/es active IP Right Grant
- 2015-09-23 AU AU2015320673A patent/AU2015320673B2/en active Active
- 2015-09-23 AP AP2017009834A patent/AP2017009834A0/en unknown
- 2015-09-23 EP EP15775553.9A patent/EP3197486B8/en active Active
- 2015-09-23 RU RU2017113571A patent/RU2745373C2/ru active
- 2015-09-23 CN CN201580057248.4A patent/CN107073100B/zh active Active
- 2015-09-23 DK DK15775553.9T patent/DK3197486T3/da active
- 2015-09-23 CA CA2962225A patent/CA2962225A1/en active Pending
- 2015-09-23 TW TW104131548A patent/TWI733653B/zh active
- 2015-09-23 KR KR1020177010941A patent/KR102526219B1/ko active Active
- 2015-09-28 JO JOP/2015/0240A patent/JO3600B1/ar active
- 2015-09-29 PY PY201501548374A patent/PY1548374A/es unknown
-
2017
- 2017-03-15 ZA ZA2017/01851A patent/ZA201701851B/en unknown
-
2019
- 2019-07-30 AU AU2019210537A patent/AU2019210537A1/en not_active Abandoned
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