JP2013518052A5 - - Google Patents

Download PDF

Info

Publication number
JP2013518052A5
JP2013518052A5 JP2012550153A JP2012550153A JP2013518052A5 JP 2013518052 A5 JP2013518052 A5 JP 2013518052A5 JP 2012550153 A JP2012550153 A JP 2012550153A JP 2012550153 A JP2012550153 A JP 2012550153A JP 2013518052 A5 JP2013518052 A5 JP 2013518052A5
Authority
JP
Japan
Prior art keywords
seq
vaccine vector
polypeptide
antigenic polypeptide
vector according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2012550153A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013518052A (ja
JP6242050B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2011/022062 external-priority patent/WO2011091255A1/en
Publication of JP2013518052A publication Critical patent/JP2013518052A/ja
Publication of JP2013518052A5 publication Critical patent/JP2013518052A5/ja
Application granted granted Critical
Publication of JP6242050B2 publication Critical patent/JP6242050B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2012550153A 2010-01-21 2011-01-21 免疫応答を増強するワクチンベクターおよび方法 Active JP6242050B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29709810P 2010-01-21 2010-01-21
US61/297,098 2010-01-21
PCT/US2011/022062 WO2011091255A1 (en) 2010-01-21 2011-01-21 Vaccine vectors and methods of enhancing immune responses

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016044306A Division JP2016117757A (ja) 2010-01-21 2016-03-08 免疫応答を増強するワクチンベクターおよび方法

Publications (3)

Publication Number Publication Date
JP2013518052A JP2013518052A (ja) 2013-05-20
JP2013518052A5 true JP2013518052A5 (enExample) 2014-03-13
JP6242050B2 JP6242050B2 (ja) 2017-12-06

Family

ID=44307229

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2012550153A Active JP6242050B2 (ja) 2010-01-21 2011-01-21 免疫応答を増強するワクチンベクターおよび方法
JP2016044306A Pending JP2016117757A (ja) 2010-01-21 2016-03-08 免疫応答を増強するワクチンベクターおよび方法
JP2017233454A Expired - Fee Related JP6687585B2 (ja) 2010-01-21 2017-12-05 免疫応答を増強するワクチンベクターおよび方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2016044306A Pending JP2016117757A (ja) 2010-01-21 2016-03-08 免疫応答を増強するワクチンベクターおよび方法
JP2017233454A Expired - Fee Related JP6687585B2 (ja) 2010-01-21 2017-12-05 免疫応答を増強するワクチンベクターおよび方法

Country Status (21)

Country Link
US (2) US8956618B2 (enExample)
EP (1) EP2525817B8 (enExample)
JP (3) JP6242050B2 (enExample)
KR (1) KR101638661B1 (enExample)
CN (1) CN102811734B (enExample)
AU (1) AU2011207331C1 (enExample)
CA (1) CA2787661C (enExample)
CL (1) CL2012002016A1 (enExample)
CO (1) CO6561819A2 (enExample)
DK (1) DK2525817T3 (enExample)
EA (1) EA023058B1 (enExample)
ES (1) ES2643646T3 (enExample)
HU (1) HUE037157T2 (enExample)
MX (1) MX341775B (enExample)
NO (1) NO2525817T3 (enExample)
NZ (1) NZ601609A (enExample)
PL (1) PL2525817T3 (enExample)
PT (1) PT2525817T (enExample)
UA (1) UA110024C2 (enExample)
WO (1) WO2011091255A1 (enExample)
ZA (1) ZA201205824B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3097926T3 (pl) * 2007-11-01 2020-04-30 The Board Of Trustees Of The University Of Arkansas Kompozycje i sposoby wzmacniania odpowiedzi odpornościowych na Eimeria
HUE037157T2 (hu) 2010-01-21 2018-08-28 Univ Arkansas Vakcinavektorok, és eljárások immunválaszok fokozására
KR102008120B1 (ko) 2010-06-09 2019-08-07 더 보드 오브 트러스티스 오브 더 유니버시티 오브 아칸소 캄필로박터 감염을 감소시키기 위한 백신 및 방법
US20190263888A1 (en) 2010-10-19 2019-08-29 Op-T Llc Therapeutic peptides and methods for treating autoimmune related disease
WO2012072788A1 (en) 2010-12-02 2012-06-07 Mab-Factory Gmbh Vaccine against influenza h5n1 viruses, medicament and treatment of h5n1 viral infections
EA030929B1 (ru) * 2013-02-14 2018-10-31 Дзе Борд Оф Трастиз Оф Дзе Юниверсити Оф Арканзас КОМПОЗИЦИИ И СПОСОБЫ УСИЛЕНИЯ ИММУННЫХ ОТВЕТОВ НА Eimeria ИЛИ ОГРАНИЧЕНИЯ ИНФЕКЦИИ Eimeria
BR112015023024B1 (pt) 2013-03-15 2022-04-19 The Board Of Trustees Of The University Of Arkansas Vetor de vacina e composições farmacêuticas compreendendo o mesmo
CN105399808B (zh) * 2015-11-23 2019-05-10 青岛农业大学 一种许氏平鮋免疫增强蛋白hmgb1基因及编码蛋白和应用
TWI758288B (zh) 2016-05-03 2022-03-21 阿肯色州大學董事會 包含免疫刺激性及抗原性多肽的酵母菌疫苗載體以及其使用方法
US11793854B2 (en) 2019-03-21 2023-10-24 Op-T Llc Methods for reducing symptoms of multiple sclerosis using a six-amino acid long peptide that inhibits CD40-CD150 interaction
US11744875B2 (en) 2019-07-12 2023-09-05 Op-T Llc Peptides and methods for treating disease
WO2021212013A2 (en) 2020-04-17 2021-10-21 Op-T Llc Bioactive peptides and methods of use thereof
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
US12537071B1 (en) 2020-07-22 2026-01-27 David Gordon Bermudes Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins

Family Cites Families (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ285118B6 (cs) 1991-03-05 1999-05-12 The Wellcome Foundation Limited Exprese rekombinačních proteinů v oslabených bakteriích
US7405270B2 (en) 1991-10-25 2008-07-29 Immunex Corporation CD40-Ligand lacking native-pattern glycosylation
US5981724A (en) 1991-10-25 1999-11-09 Immunex Corporation DNA encoding CD40 ligand, a cytokine that binds CD40
DE69233051T2 (de) 1991-10-25 2004-03-11 Immunex Corp., Seattle Antikörper gegen CD40-L
US5962406A (en) 1991-10-25 1999-10-05 Immunex Corporation Recombinant soluble CD40 ligand polypeptide and pharmaceutical composition containing the same
CA2143299A1 (en) 1992-09-04 1994-03-17 University Of Saskatchewan Novel bacterial vaccines using vaccine strains of pathogenic bacteria
AU1059095A (en) 1993-11-24 1995-06-13 Australian National University, The Treatment of viral disease with cd40l peptide
AU699291B2 (en) 1995-03-01 1998-11-26 Immunex Corporation Method for stimulating an immune response
AU693713B2 (en) 1995-06-07 1998-07-02 Immunex Corporation CD40L mutein
US6713279B1 (en) 1995-12-07 2004-03-30 Diversa Corporation Non-stochastic generation of genetic vaccines and enzymes
US6479258B1 (en) 1995-12-07 2002-11-12 Diversa Corporation Non-stochastic generation of genetic vaccines
US6306387B1 (en) 1997-05-29 2001-10-23 The Research Foundation Of State University Of New York Antigen delivery system
US20030045492A1 (en) 1997-08-13 2003-03-06 Tang De-Chu C. Vaccination by topical application of recombinant vectors
US6969609B1 (en) 1998-12-09 2005-11-29 The United States Of America As Represented By The Department Of Health And Human Serivces Recombinant vector expressing multiple costimulatory molecules and uses thereof
CA2223225A1 (en) 1997-11-28 1999-05-28 Canadian Red Cross Society Method for inhibiting in vivo immune response
JP2001526241A (ja) 1997-12-19 2001-12-18 イミュネックス・コーポレーション Hiv感染に対する感受性を低下させるための方法
GB9806449D0 (en) 1998-03-25 1998-05-27 Peptide Therapeutics Ltd Attenuated bacteria useful in vaccines
US6190669B1 (en) 1998-05-13 2001-02-20 University Of Maryland, Baltimore Attenuated mutants of salmonella which constitutively express the Vi antigen
IT1299583B1 (it) 1998-05-19 2000-03-16 Vander Way Limited Uso di proteine hmg-i per la preparazione di medicamenti ad attivita' citotossica
PT1108034E (pt) 1998-09-04 2008-11-14 Emergent Product Dev Uk Ltd Mutantes de spi2 de salmonela atenuados como transportadores de antigénios
US7300774B1 (en) 1999-12-09 2007-11-27 The Regents Of The University Of California Multimeric fusion proteins of the TNF superfamily ligands
EP1067194A1 (en) 1999-04-16 2001-01-10 F. Hoffmann-La Roche Ag Vectors containing a gene coding for CD40 and/or CD40L under the control of a cytokine-inducible promoter which is a human acute phase amyloid A gene promoter. Methods for their production and uses thereof
JP2003508016A (ja) 1999-04-16 2003-03-04 エフ.ホフマン−ラ ロシュ アーゲー Cd40/cd40lキメラポリペプチドをコードする核酸、それらの生成方法及びそれらの使用
US7118751B1 (en) 1999-10-14 2006-10-10 Trubion Pharmaceuticals, Inc. DNA vaccines encoding antigen linked to a domain that binds CD40
ES2222152T3 (es) 1999-12-28 2005-02-01 Akzo Nobel N.V. Vacuna con las salmonellas que no inducen anticuerpos que reaccionan con la flagelina o los flagelos.
CA2399790C (en) 2000-02-02 2012-10-30 Ralph A. Tripp Cd40 ligand adjuvant for respiratory syncytial virus
MXPA02008748A (es) 2000-03-17 2003-02-24 Upjohn Co Materiales y metodos para vacuna antisalmonella.
GB0015426D0 (en) 2000-06-24 2000-08-16 Univ Southampton Method for generating soluble highly multimeric proteins
EP1299115A2 (en) 2000-06-26 2003-04-09 Maxygen, Inc. Methods and compositions for developing spore display systems for medicinal and industrial applications
WO2002036769A2 (en) 2000-10-31 2002-05-10 F. Hoffmann-La Roche Ag Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof
HUP0500042A3 (en) 2001-05-15 2010-01-28 Long Island Jewish Res Inst Use of hmg fragments as anti-inflammatory agents
EP2687593A1 (en) 2001-05-15 2014-01-22 Ortho-McNeil Pharmaceutical, Inc. Ex-vivo priming for generating cytotoxic T lymphocytes specific for non-tumor antigens to treat autoimmune and allergic disease
US7220723B2 (en) 2001-05-15 2007-05-22 The Feinstein Institute For Medical Research Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents
ITMI20011986A1 (it) 2001-09-25 2003-03-25 San Raffaele Centro Fond Metodo e composizione per l'attivazione di cellule presentanti l'antigene
EP1453531B1 (de) 2001-12-19 2008-05-14 Alcedo Biotech GmbH Verwendung von hmgb-proteinen und dafür codierenden nukleinsäuren
US6923958B2 (en) 2002-03-02 2005-08-02 The Scripps Research Institute DNA vaccines encoding CEA and a CD40 ligand and methods of use thereof
US8133493B2 (en) 2002-04-15 2012-03-13 Washington University Regulated attenuation of live vaccines to enhance cross-protective immunogenicity
US7495090B2 (en) 2002-05-23 2009-02-24 The Regents Of The University Of California Nucleic acids encoding chimeric CD154 polypeptides
US20040141948A1 (en) 2002-11-20 2004-07-22 Critical Therapeutics, Inc. Use of HMGB fragments as anti-inflammatory agents
JP2006510619A (ja) 2002-11-20 2006-03-30 クリティカル セラピューティクス,インコーポレイテッド 抗炎症剤としてのhmgb断片の使用
US20040156851A1 (en) 2002-11-20 2004-08-12 Critical Therapeutics, Inc. HMGB1 combination therapies
EP1567544A4 (en) 2002-11-20 2009-07-22 Long Island Jewish Res Inst USE OF HMGB POLYPEPTIDES TO IMPROVE THE IMMUNE REACTIONS
US20060014248A1 (en) 2003-01-06 2006-01-19 Xencor, Inc. TNF super family members with altered immunogenicity
US20050181994A1 (en) 2003-01-06 2005-08-18 Xencor, Inc. Novel variants of CD40L protein
US7696169B2 (en) 2003-06-06 2010-04-13 The Feinstein Institute For Medical Research Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents
US7754209B2 (en) 2003-07-26 2010-07-13 Trubion Pharmaceuticals Binding constructs and methods for use thereof
WO2005025604A2 (en) 2003-09-10 2005-03-24 The General Hospital Corporation Use of hmgb and hmgb fragments to decrease specific immune response
WO2005035570A2 (en) 2003-10-10 2005-04-21 Xencor, Inc. Variants of cd40l protein
CA2548347A1 (en) 2003-12-11 2005-06-30 Sidney Kimmel Cancer Center Methods for generating immunity to antigen
US8828957B2 (en) 2003-12-11 2014-09-09 Microvax, Llc Methods for generating immunity to antigen
US20070128183A1 (en) 2004-04-27 2007-06-07 Intercell Ag Td antigens
WO2005113598A2 (en) 2004-05-21 2005-12-01 Xencor, Inc. Tnf super family members with altered immunogenicity
WO2006083301A2 (en) * 2004-06-17 2006-08-10 Medimmune, Inc. Immunogenic compositions comprising hmgb1 polypeptides
WO2006012373A2 (en) 2004-07-20 2006-02-02 Critical Therapeutics, Inc. Combination therapies of hmgb and complement inhibitors against inflammation
US8513008B2 (en) 2004-10-07 2013-08-20 Argos Therapeutics, Inc. Mature dendritic cell compositions and methods for culturing same
CN101080487B (zh) 2004-10-07 2012-11-14 阿戈斯治疗公司 成熟树突细胞组合物及其培养方法
GB0423681D0 (en) 2004-10-26 2004-11-24 Sec Dep For Environment Food & Vaccine and nucleic acids
JP2008524261A (ja) 2004-12-21 2008-07-10 バクシネート コーポレーション インフルエンザウイルスタンパク質の組成物およびその使用方法
WO2006105972A1 (en) 2005-04-07 2006-10-12 Universite Libre De Bruxelles Transgenic organism expressing cd40l and uses thereof
US20060286074A1 (en) 2005-05-31 2006-12-21 Yucheng Tang Methods for immunotherapy of cancer
EP1909834A2 (en) 2005-07-18 2008-04-16 Critical Therapeutics, Inc. Use of hmgb1 antagonists for the treatment of inflammatory skin conditions
PL1949913T3 (pl) 2005-10-07 2010-10-29 Proyecto De Biomedicina Cima S L Immunostymulująca kombinacja do profilaktyki i leczenia wirusowego zapalenia wątroby typu c
CA2628837C (en) 2005-11-07 2018-11-27 Sidney Kimmel Cancer Center Cd40 ligand fusion protein vaccine
WO2007054658A1 (en) 2005-11-14 2007-05-18 King's College London Control of immune responses
WO2007130725A2 (en) * 2006-02-06 2007-11-15 University Of Pittsburgh Of The Commonwealth System Of Higher Education Use of hmgb1 for protection against ischemia reperfusion injury
WO2007103048A2 (en) 2006-03-01 2007-09-13 Regents Of The University Of Colorado Tlr agonist (flagellin)/cd40 agonist/antigen protein and dna conjugates and use thereof for inducing synergistic enhancement in immunity
US8802419B2 (en) 2006-03-02 2014-08-12 University Of Massachusetts Modified pathogens for use as vaccines
EP2044198A4 (en) * 2006-07-27 2010-09-08 Ligocyte Pharmaceuticals Inc CHIMERIC INFLUENZA VIRUS TYPE PARTICLES
US8564612B2 (en) * 2006-08-04 2013-10-22 Apple Inc. Deep pixel pipeline
AU2007286161B2 (en) * 2006-08-09 2013-05-02 Medimmune, Llc Influenza hemagglutinin and neuraminidase variants
US8604178B2 (en) 2006-09-18 2013-12-10 The Board Of Trustees Of The University Of Arkansas Compositions and methods of enhancing immune responses
WO2008109825A2 (en) 2007-03-08 2008-09-12 Mayo Foundation For Medical Education And Research Inducing immune-mediated tumor cell death
EP2152730A4 (en) * 2007-05-02 2011-08-03 Univ Emory ENLARGEMENT OF GLYCOPROTEININCORPORATION IN VIRUSUAL PARTICLES
US9125854B2 (en) 2007-10-30 2015-09-08 The Board Of Trustees Of The University Of Arkansas Compositions and methods of enhancing immune responses to flagellated bacterium
PL3097926T3 (pl) 2007-11-01 2020-04-30 The Board Of Trustees Of The University Of Arkansas Kompozycje i sposoby wzmacniania odpowiedzi odpornościowych na Eimeria
HUE037157T2 (hu) 2010-01-21 2018-08-28 Univ Arkansas Vakcinavektorok, és eljárások immunválaszok fokozására
WO2013071298A1 (en) 2011-11-11 2013-05-16 Nutrition Physiology Company, Llc Lactic acid bacteria and their use as dietary supplementals for poultry
KR102008120B1 (ko) 2010-06-09 2019-08-07 더 보드 오브 트러스티스 오브 더 유니버시티 오브 아칸소 캄필로박터 감염을 감소시키기 위한 백신 및 방법

Similar Documents

Publication Publication Date Title
JP2013518052A5 (enExample)
Levi et al. Synthetic recombinant influenza vaccine induces efficient long-term immunity and cross-strain protection
Rajao et al. Pathogenesis and vaccination of influenza A virus in swine
JP2015536134A5 (enExample)
JP2016539946A5 (enExample)
JP2012523246A5 (enExample)
JP2008530245A5 (enExample)
CN106659777A8 (zh) 免疫原性组合产品
JP2011502165A5 (enExample)
JP2015214545A5 (enExample)
JP2010500399A5 (enExample)
JP2012126742A5 (enExample)
JP2008500399A5 (enExample)
Kim et al. Influenza M2 virus-like particles confer a broader range of cross protection to the strain-specific pre-existing immunity
MX341775B (es) Vectores para vacunas y metodos para potenciar respuestas inmunes.
JP2010516713A5 (enExample)
JP2012519724A5 (enExample)
JP2018531578A5 (enExample)
JP2010506926A5 (enExample)
JP2016520534A5 (enExample)
Yang et al. Protection against influenza H7N9 virus challenge with a recombinant NP–M1–HSP60 protein vaccine construct in BALB/c mice
Gasparini et al. Live attenuated influenza vaccine–a review
JP2015525794A5 (enExample)
CN107961371B (zh) 季节流感-rsv联合疫苗及其制备方法和应用
WO2015049633A1 (es) FORMULACION INMUNOGENICA QUE CONTIENE BCG VIVAS RECOMBINANTES QUE EXPRESAN ANTIGENOS DE METAPNEUMOVIRUS (hMPV), EN UNA SUSPENSION QUE SE PREPARA A PARTIR DE UN LIOFILIZADO SIN LA NECESIDAD DE ADJUVANTE, APTA PARA SU USO FARMACEUTICO.