JP2012519724A5 - - Google Patents
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- Publication number
- JP2012519724A5 JP2012519724A5 JP2011553432A JP2011553432A JP2012519724A5 JP 2012519724 A5 JP2012519724 A5 JP 2012519724A5 JP 2011553432 A JP2011553432 A JP 2011553432A JP 2011553432 A JP2011553432 A JP 2011553432A JP 2012519724 A5 JP2012519724 A5 JP 2012519724A5
- Authority
- JP
- Japan
- Prior art keywords
- ctb
- hapten
- subunit
- inducing
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000009016 Cholera Toxin Human genes 0.000 claims 2
- 108010049048 Cholera Toxin Proteins 0.000 claims 2
- 108010076504 Protein Sorting Signals Proteins 0.000 claims 1
- 238000001467 acupuncture Methods 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 210000004900 c-terminal fragment Anatomy 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000002163 immunogen Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20962909P | 2009-03-09 | 2009-03-09 | |
| US61/209,629 | 2009-03-09 | ||
| PCT/EP2010/052997 WO2010103017A2 (en) | 2009-03-09 | 2010-03-09 | Hapten-carrier conjugates with bacterial toxins having a signal peptide as carrier and their use in immunogenic compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012519724A JP2012519724A (ja) | 2012-08-30 |
| JP2012519724A5 true JP2012519724A5 (enExample) | 2013-04-25 |
Family
ID=42555592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011553432A Pending JP2012519724A (ja) | 2009-03-09 | 2010-03-09 | シグナルペプチドを担体として有する細菌毒素とのハプテン‐担体抱合体及び免疫原性組成物としてのその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20120100171A1 (enExample) |
| EP (1) | EP2405943A2 (enExample) |
| JP (1) | JP2012519724A (enExample) |
| KR (1) | KR20120022760A (enExample) |
| CN (1) | CN102427828A (enExample) |
| CA (1) | CA2754592A1 (enExample) |
| MX (1) | MX2011009359A (enExample) |
| RU (1) | RU2011140858A (enExample) |
| WO (1) | WO2010103017A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8728478B2 (en) * | 2008-09-03 | 2014-05-20 | Board Of Trustees Of Michigan State University | Immunogenic Escherichia coli heat stable enterotoxin |
| ES2732815T3 (es) | 2009-05-22 | 2019-11-26 | Genocea Biosciences Inc | Vacunas frente al virus del herpes simple de tipo 2: composiciones y métodos para provocar una respuesta inmunitaria |
| EP2482838A4 (en) * | 2009-09-30 | 2013-04-10 | Toxcure Inc | USE OF BOTULINUM NEUROTOXIN FOR THE TREATMENT OF SUBSTANCE DEPENDENCE |
| CA2856697A1 (en) | 2010-11-24 | 2012-06-07 | Genocea Biosciences, Inc. | Vaccines against herpes simplex virus type 2: compositions and methods for eliciting an immune response |
| WO2012125720A2 (en) | 2011-03-14 | 2012-09-20 | University Of Louisville Research Foundation, Inc. | Polypeptides having immunoactivating activity and methods of producing the same |
| EP3313866B1 (en) | 2015-06-29 | 2024-11-20 | University Of Louisville Research Foundation, Inc. | Compositions and methods for treating cancer and promoting wound healing |
| JP2019537555A (ja) | 2016-09-28 | 2019-12-26 | ジェノセア バイオサイエンシーズ， インコーポレイテッド | ヘルペスを処置するための方法および組成物 |
| WO2018060351A1 (en) * | 2016-09-29 | 2018-04-05 | Ipsen Biopharm Limited | Hybrid neurotoxins |
| EP3973253A4 (en) * | 2019-05-20 | 2022-08-10 | Siemens Healthcare Diagnostics, Inc. | PROCEDURE FOR DETECTING ABERRANTIC RESULTS DUE TO INCOMPLETE DELIVERY OF A POLYHAPTEN REAGENT IN IMMUNOASSAYS |
| JP7555363B2 (ja) | 2019-07-03 | 2024-09-24 | インターベット インターナショナル ベー． フェー． | マイコトキシン症に対する防御のためのコンジュゲート化デオキシニバレノール |
| US12343375B2 (en) | 2021-02-09 | 2025-07-01 | University Of Louisville Research Foundation, Inc. | Spray dried formulation of a cholera toxin B subunit variant |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5171568A (en) | 1984-04-06 | 1992-12-15 | Chiron Corporation | Recombinant herpes simplex gb-gd vaccine |
| US4883761A (en) | 1986-03-25 | 1989-11-28 | The United States Of America As Represented By The Department Of Health And Human Services | Pertussis toxin gene: cloning and expression of protective antigen |
| EP0251575B2 (en) | 1986-06-17 | 2002-11-13 | Chiron Corporation | Hepatitis delta diagnostics and vaccines, their preparation and use |
| WO1989004669A1 (en) | 1987-11-18 | 1989-06-01 | Chiron Corporation | Nanbv diagnostics and vaccines |
| WO1990011089A1 (en) | 1989-03-17 | 1990-10-04 | Chiron Corporation | Nanbv diagnostics and vaccines |
| ATE211772T1 (de) | 1989-05-18 | 2002-01-15 | Chiron Corp | Nanbv-diagnostika: polynukleotide, geeignet für reihenuntersuchungen auf hepatitis c-virus |
| US5840307A (en) * | 1995-03-31 | 1998-11-24 | Immulogic Pharmacuetical Corp. | Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation |
| US5876727A (en) | 1995-03-31 | 1999-03-02 | Immulogic Pharmaceutical Corporation | Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same |
| US20020032316A1 (en) | 1995-03-31 | 2002-03-14 | Cantab Pharmaceuticals Research Limited | Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same |
| FR2768747B1 (fr) | 1997-09-19 | 2000-12-01 | Pasteur Institut | Acides nucleiques, cellules recombinantes, et procede de preparation de compositions immunogenes |
| CN1231586C (zh) * | 2003-04-15 | 2005-12-14 | 中国科学院微生物研究所 | 一种多形汉逊酵母表达重组霍乱毒素b亚单位基因及其应用 |
| GB0325494D0 (en) * | 2003-10-31 | 2003-12-03 | Sbl Vaccin Ab | Expression system |
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2010
- 2010-03-09 KR KR1020117023547A patent/KR20120022760A/ko not_active Withdrawn
- 2010-03-09 MX MX2011009359A patent/MX2011009359A/es not_active Application Discontinuation
- 2010-03-09 WO PCT/EP2010/052997 patent/WO2010103017A2/en not_active Ceased
- 2010-03-09 RU RU2011140858/15A patent/RU2011140858A/ru not_active Application Discontinuation
- 2010-03-09 JP JP2011553432A patent/JP2012519724A/ja active Pending
- 2010-03-09 CA CA2754592A patent/CA2754592A1/en not_active Abandoned
- 2010-03-09 CN CN2010800175877A patent/CN102427828A/zh active Pending
- 2010-03-09 EP EP10706688A patent/EP2405943A2/en not_active Withdrawn
- 2010-03-09 US US13/255,262 patent/US20120100171A1/en not_active Abandoned