JP2012519724A5 - - Google Patents
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- Publication number
- JP2012519724A5 JP2012519724A5 JP2011553432A JP2011553432A JP2012519724A5 JP 2012519724 A5 JP2012519724 A5 JP 2012519724A5 JP 2011553432 A JP2011553432 A JP 2011553432A JP 2011553432 A JP2011553432 A JP 2011553432A JP 2012519724 A5 JP2012519724 A5 JP 2012519724A5
- Authority
- JP
- Japan
- Prior art keywords
- ctb
- hapten
- subunit
- inducing
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- YDXZSNHARVUYNM-UHFFFAOYSA-N N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxybenzamide Chemical compound CCOC1=CC=CC=C1C(=O)NC1=CC=C(Cl)C(C(F)(F)F)=C1 YDXZSNHARVUYNM-UHFFFAOYSA-N 0.000 claims 2
- 210000004900 C-terminal fragment Anatomy 0.000 claims 1
- 238000001467 acupuncture Methods 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drugs Drugs 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000002163 immunogen Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
Claims (1)
- （i）アミノ酸配列
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20962909P | 2009-03-09 | 2009-03-09 | |
| US61/209,629 | 2009-03-09 | ||
| PCT/EP2010/052997 WO2010103017A2 (en) | 2009-03-09 | 2010-03-09 | Hapten-carrier conjugates with bacterial toxins having a signal peptide as carrier and their use in immunogenic compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012519724A JP2012519724A (ja) | 2012-08-30 |
| JP2012519724A5 true JP2012519724A5 (ja) | 2013-04-25 |
Family
ID=42555592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011553432A Pending JP2012519724A (ja) | 2009-03-09 | 2010-03-09 | シグナルペプチドを担体として有する細菌毒素とのハプテン‐担体抱合体及び免疫原性組成物としてのその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20120100171A1 (ja) |
| EP (1) | EP2405943A2 (ja) |
| JP (1) | JP2012519724A (ja) |
| KR (1) | KR20120022760A (ja) |
| CN (1) | CN102427828A (ja) |
| CA (1) | CA2754592A1 (ja) |
| MX (1) | MX2011009359A (ja) |
| RU (1) | RU2011140858A (ja) |
| WO (1) | WO2010103017A2 (ja) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2730328C (en) * | 2008-09-03 | 2015-03-31 | Board Of Trustees Of Michigan State University | Immunogenic escherichia coli heat stable enterotoxin |
| EP3756684A1 (en) | 2009-05-22 | 2020-12-30 | Genocea Biosciences, Inc. | Vaccines against herpes simplex virus type 2: compositions and methods for eliciting an immune response |
| WO2011041483A2 (en) * | 2009-09-30 | 2011-04-07 | Toxcure, Inc. | Use of botulinum neurotoxin to treat substance addictions |
| EP2643014A4 (en) | 2010-11-24 | 2015-11-11 | Genocea Biosciences Inc | HERPES SIMPLEX TYPE 2 VIRUS VACCINES: COMPOSITIONS AND METHODS FOR STIMULATING AN IMMUNE RESPONSE |
| WO2012125720A2 (en) | 2011-03-14 | 2012-09-20 | University Of Louisville Research Foundation, Inc. | Polypeptides having immunoactivating activity and methods of producing the same |
| US10758605B2 (en) | 2015-06-29 | 2020-09-01 | University Of Louisville Research Foundation, Inc. | Compositions and methods for treating cancer and promoting wound healing |
| US10350288B2 (en) | 2016-09-28 | 2019-07-16 | Genocea Biosciences, Inc. | Methods and compositions for treating herpes |
| CN109790204A (zh) * | 2016-09-29 | 2019-05-21 | 益普生生物制药有限公司 | 杂合神经毒素 |
| CN113825984B (zh) * | 2019-05-20 | 2024-08-13 | 美国西门子医学诊断股份有限公司 | 用于检测免疫测定中由多半抗原试剂的不完全递送引起的异常结果的方法 |
| MX2021015837A (es) * | 2019-07-03 | 2022-02-03 | Intervet Int Bv | Desoxinivalenol conjugado para proteger contra micotoxicosis. |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5171568A (en) | 1984-04-06 | 1992-12-15 | Chiron Corporation | Recombinant herpes simplex gb-gd vaccine |
| US4883761A (en) | 1986-03-25 | 1989-11-28 | The United States Of America As Represented By The Department Of Health And Human Services | Pertussis toxin gene: cloning and expression of protective antigen |
| CA1338800C (en) | 1986-06-17 | 1996-12-17 | Michael Houghton | Hepatitis delta and diagnostics and vaccines |
| CN1049686C (zh) | 1987-11-18 | 2000-02-23 | 希龙股份有限公司 | 非ａ和非ｂ肝炎病毒的诊断及疫苗 |
| KR0185373B1 (ko) | 1989-03-17 | 1999-05-01 | 로버트 피. 블랙버언 | Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용 |
| DK0398748T3 (da) | 1989-05-18 | 2002-03-18 | Chiron Corp | NANBV-diagnostika: polynukleotider anvendelige til screening for hepatitis C virus |
| US5876727A (en) | 1995-03-31 | 1999-03-02 | Immulogic Pharmaceutical Corporation | Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same |
| US5840307A (en) | 1995-03-31 | 1998-11-24 | Immulogic Pharmacuetical Corp. | Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation |
| US20020032316A1 (en) | 1995-03-31 | 2002-03-14 | Cantab Pharmaceuticals Research Limited | Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same |
| FR2768747B1 (fr) | 1997-09-19 | 2000-12-01 | Pasteur Institut | Acides nucleiques, cellules recombinantes, et procede de preparation de compositions immunogenes |
| CN1231586C (zh) * | 2003-04-15 | 2005-12-14 | 中国科学院微生物研究所 | 一种多形汉逊酵母表达重组霍乱毒素b亚单位基因及其应用 |
| GB0325494D0 (en) | 2003-10-31 | 2003-12-03 | Sbl Vaccin Ab | Expression system |
-
2010
- 2010-03-09 US US13/255,262 patent/US20120100171A1/en not_active Abandoned
- 2010-03-09 CN CN2010800175877A patent/CN102427828A/zh active Pending
- 2010-03-09 CA CA2754592A patent/CA2754592A1/en not_active Abandoned
- 2010-03-09 KR KR1020117023547A patent/KR20120022760A/ko not_active Application Discontinuation
- 2010-03-09 JP JP2011553432A patent/JP2012519724A/ja active Pending
- 2010-03-09 EP EP10706688A patent/EP2405943A2/en not_active Withdrawn
- 2010-03-09 RU RU2011140858/15A patent/RU2011140858A/ru not_active Application Discontinuation
- 2010-03-09 MX MX2011009359A patent/MX2011009359A/es not_active Application Discontinuation
- 2010-03-09 WO PCT/EP2010/052997 patent/WO2010103017A2/en active Application Filing
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