JP2010011868A5 - - Google Patents
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- Publication number
- JP2010011868A5 JP2010011868A5 JP2009238784A JP2009238784A JP2010011868A5 JP 2010011868 A5 JP2010011868 A5 JP 2010011868A5 JP 2009238784 A JP2009238784 A JP 2009238784A JP 2009238784 A JP2009238784 A JP 2009238784A JP 2010011868 A5 JP2010011868 A5 JP 2010011868A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- bacteria
- immune response
- neisseria meningitidis
- serosubtype
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000894006 Bacteria Species 0.000 claims 3
- 230000028993 immune response Effects 0.000 claims 3
- 241000588677 Neisseria meningitidis serogroup B Species 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 241000588650 Neisseria meningitidis Species 0.000 claims 1
- 108700022034 Opsonin Proteins Proteins 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 230000000844 anti-bacterial effect Effects 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 230000001747 exhibiting effect Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28455401P | 2001-04-17 | 2001-04-17 | |
| US60/284,554 | 2001-04-17 | ||
| US32683801P | 2001-10-03 | 2001-10-03 | |
| US60/326,838 | 2001-10-03 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008074708A Division JP2008259503A (ja) | 2001-04-17 | 2008-03-21 | 機能活性抗体を誘発する髄膜炎菌性bエピトープの分子模倣物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010011868A JP2010011868A (ja) | 2010-01-21 |
| JP2010011868A5 true JP2010011868A5 (enExample) | 2012-01-05 |
| JP5215275B2 JP5215275B2 (ja) | 2013-06-19 |
Family
ID=26962673
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002581466A Withdrawn JP2004529643A (ja) | 2001-04-17 | 2002-04-11 | 機能活性抗体を誘発する髄膜炎菌性bエピトープの分子模倣物 |
| JP2008074708A Withdrawn JP2008259503A (ja) | 2001-04-17 | 2008-03-21 | 機能活性抗体を誘発する髄膜炎菌性bエピトープの分子模倣物 |
| JP2009238784A Expired - Fee Related JP5215275B2 (ja) | 2001-04-17 | 2009-10-15 | 機能活性抗体を誘発する髄膜炎菌性bエピトープの分子模倣物 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002581466A Withdrawn JP2004529643A (ja) | 2001-04-17 | 2002-04-11 | 機能活性抗体を誘発する髄膜炎菌性bエピトープの分子模倣物 |
| JP2008074708A Withdrawn JP2008259503A (ja) | 2001-04-17 | 2008-03-21 | 機能活性抗体を誘発する髄膜炎菌性bエピトープの分子模倣物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7534444B2 (enExample) |
| EP (1) | EP1379272B1 (enExample) |
| JP (3) | JP2004529643A (enExample) |
| CN (1) | CN1306956C (enExample) |
| AT (1) | ATE455793T1 (enExample) |
| AU (1) | AU2002252638A1 (enExample) |
| CA (1) | CA2439428C (enExample) |
| DE (1) | DE60235155D1 (enExample) |
| RU (1) | RU2322451C2 (enExample) |
| WO (1) | WO2002083711A2 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4812942B2 (ja) * | 1999-02-26 | 2011-11-09 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | CGモチーフを含むオリゴヌクレオチドを用いるNeisseria抗原殺菌活性の増強 |
| US6977245B2 (en) | 1999-04-12 | 2005-12-20 | The United States Of America As Represented By The Department Of Health And Human Services | Oligodeoxynucleotide and its use to induce an immune response |
| CA2838395C (en) | 1999-05-19 | 2016-07-19 | Novartis Vaccines And Diagnostics S.R.L. | Combination neisserial compositions |
| DE60131430T2 (de) | 2000-01-14 | 2008-10-16 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Oligodeoxynukleotide und ihre verwendung zur induktion einer immunreaktion |
| WO2002020059A2 (en) * | 2000-09-01 | 2002-03-14 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Vibrio cholerae o139 conjugate vaccines |
| GB0024200D0 (en) * | 2000-10-03 | 2000-11-15 | Smithkline Beecham Sa | Component vaccine |
| US7666674B2 (en) | 2001-07-27 | 2010-02-23 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Use of sterically stabilized cationic liposomes to efficiently deliver CPG oligonucleotides in vivo |
| US7354909B2 (en) * | 2001-08-14 | 2008-04-08 | The United States Of America As Represented By Secretary Of The Department Of Health And Human Services | Method for rapid generation of mature dendritic cells |
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| US8466116B2 (en) | 2001-12-20 | 2013-06-18 | The Unites States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Use of CpG oligodeoxynucleotides to induce epithelial cell growth |
| US7615227B2 (en) * | 2001-12-20 | 2009-11-10 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Use of CpG oligodeoxynucleotides to induce angiogenesis |
| US8263091B2 (en) * | 2002-09-18 | 2012-09-11 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method of treating and preventing infections in immunocompromised subjects with immunostimulatory CpG oligonucleotides |
| WO2005023295A2 (en) * | 2003-09-10 | 2005-03-17 | De Staat Der Nederlanden, Vert. Door De Minister Van Vws | Naturally processed immunodominant peptides derived from neisseria meningitidis porin a protein and their use |
| CA2555342A1 (en) * | 2004-02-18 | 2005-09-01 | Merck & Co., Inc. | Polypeptides for inducing a protective immune response against staphylococcus aureus |
| DE102004023906A1 (de) * | 2004-05-13 | 2005-12-22 | GESELLSCHAFT FüR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF) | Verfahren zur Herstellung von chemischen Mikroarrays |
| CN105315347A (zh) | 2005-11-30 | 2016-02-10 | 株式会社癌免疫研究所 | 新型肽化合物 |
| GB0611914D0 (en) * | 2006-06-15 | 2006-07-26 | Teti Giuseppe | Peptides that mimic non-human cross-reactive protective epitopes of the group Bmeningococcal capsulsar polysaccharide |
| AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
| US10527329B2 (en) | 2008-04-18 | 2020-01-07 | Denso Corporation | Ejector-type refrigeration cycle device |
| SI3831406T1 (sl) | 2010-08-23 | 2024-08-30 | Wyeth Llc | Stabilne formulacije antigenov neisseria meningitidis RLP2086 |
| NZ607224A (en) | 2010-09-10 | 2014-11-28 | Wyeth Llc | Non-lipidated variants of neisseria meningitidis orf2086 antigens |
| EP2823312B1 (en) * | 2012-03-08 | 2019-08-07 | GlaxoSmithKline Biologicals SA | In vitro potency assay for protein-based meningococcal vaccines |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| RU2665841C2 (ru) | 2012-03-09 | 2018-09-04 | Пфайзер Инк. | Композиции neisseria meningitidis и способы их применения |
| EP2964665B1 (en) | 2013-03-08 | 2018-08-01 | Pfizer Inc | Immunogenic fusion polypeptides |
| BR112016004463A2 (pt) | 2013-09-08 | 2017-10-17 | Pfizer | composições de neisseria meningitidis e métodos das mesmas |
| US10888611B2 (en) | 2015-02-19 | 2021-01-12 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| CN118021947A (zh) | 2017-01-31 | 2024-05-14 | 辉瑞大药厂 | 脑膜炎奈瑟菌组合物及其使用方法 |
| MX2022003682A (es) | 2019-09-27 | 2022-04-25 | Pfizer | Composiciones de neisseria meningitidis y metodos de las mismas. |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4356170A (en) | 1981-05-27 | 1982-10-26 | Canadian Patents & Development Ltd. | Immunogenic polysaccharide-protein conjugates |
| JPH0720878B2 (ja) | 1983-11-21 | 1995-03-08 | ザ ウエルカム フアウンデ−シヨン リミテツド | 改善された複合体、それらの製造法および該複合体を含有する製剤 |
| US4727136A (en) | 1985-10-01 | 1988-02-23 | Canadian Patents And Development Ltd. | Modified meningococcal group B polysaccharide for conjugate vaccine |
| US4970070A (en) | 1986-02-07 | 1990-11-13 | Genetic Systems Corporation | Protective monoclonal antibody compositions for infections due to group B streptococcus |
| JPH01125328A (ja) * | 1987-07-30 | 1989-05-17 | Centro Natl De Biopreparados | 髄膜炎菌ワクチン |
| ATE120093T1 (de) | 1988-12-19 | 1995-04-15 | Praxis Biolog Inc | Meningococcales klasse i-aussenmembranprotein- vakzin. |
| US5128460A (en) * | 1989-04-04 | 1992-07-07 | Genelabs Incorporated | Recombinant trichosanthin and coding sequence |
| US5399346A (en) | 1989-06-14 | 1995-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Gene therapy |
| SU1708846A1 (ru) * | 1989-11-22 | 1992-01-30 | Научно-исследовательский институт вакцин и сывороток им.И.И.Мечникова | Штамм бактерий NeISSeRIa меNINGIтIDIS серогруппы В - продуцент капсульного полисахарида и полисахаридно-белкового комплекса |
| HU9201966D0 (en) | 1989-12-14 | 1992-10-28 | Ca Nat Research Council | An improved vaccine of meningococcus-polysaccharide conjunction |
| RU2068270C1 (ru) * | 1993-01-13 | 1996-10-27 | Научно-исследовательский институт вакцин и сывороток им.И.И.Мечникова | Антиген менингококков группы в |
| US5510264A (en) * | 1993-09-28 | 1996-04-23 | Insight Biotech Inc. | Antibodies which bind meningitis related homologous antigenic sequences |
| GB9422096D0 (en) | 1994-11-02 | 1994-12-21 | Biocine Spa | Combined meningitis vaccine |
| US5811102A (en) | 1995-06-07 | 1998-09-22 | National Research Council Of Canada | Modified meningococcal polysaccharide conjugate vaccines |
| EP0939647B2 (en) | 1996-08-27 | 2006-07-12 | Chiron Corporation | Neisseria meningitidis serogroup b glycoconjugates and methods of using the same |
| JP4150082B2 (ja) | 1996-08-27 | 2008-09-17 | カイロン コーポレイション | 独特の髄膜炎菌性bエピトープを規定するモノクローナル抗体およびワクチン組成物の調製におけるそれらの使用 |
| EP1007546B1 (en) | 1997-08-27 | 2009-01-21 | Novartis Vaccines and Diagnostics, Inc. | Molecular mimetics of meningococcal b epitopes |
| NZ532665A (en) * | 1998-05-01 | 2005-11-25 | Inst Genomic Research | Neisseria meningitidis antigens and compositions |
| JP4812942B2 (ja) | 1999-02-26 | 2011-11-09 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | CGモチーフを含むオリゴヌクレオチドを用いるNeisseria抗原殺菌活性の増強 |
| DK1228217T3 (da) * | 1999-04-30 | 2013-02-25 | Novartis Vaccines & Diagnostic | Konserverede neisseria-antigener |
| BR0010361A (pt) * | 1999-04-30 | 2003-06-10 | Chiron Corp | Seq ências genÈmicas de neisseria e uso destas |
| DE60144353D1 (de) * | 2000-02-28 | 2011-05-12 | Novartis Vaccines & Diagnostic | Hybride Expression Neisserscher Proteine |
-
2002
- 2002-04-11 US US10/121,456 patent/US7534444B2/en not_active Expired - Fee Related
- 2002-04-11 AU AU2002252638A patent/AU2002252638A1/en not_active Abandoned
- 2002-04-11 RU RU2003133300/13A patent/RU2322451C2/ru not_active IP Right Cessation
- 2002-04-11 AT AT02721722T patent/ATE455793T1/de not_active IP Right Cessation
- 2002-04-11 EP EP02721722A patent/EP1379272B1/en not_active Expired - Lifetime
- 2002-04-11 DE DE60235155T patent/DE60235155D1/de not_active Expired - Lifetime
- 2002-04-11 CA CA2439428A patent/CA2439428C/en not_active Expired - Fee Related
- 2002-04-11 JP JP2002581466A patent/JP2004529643A/ja not_active Withdrawn
- 2002-04-11 WO PCT/US2002/011501 patent/WO2002083711A2/en not_active Ceased
- 2002-04-11 CN CNB028081668A patent/CN1306956C/zh not_active Expired - Fee Related
-
2008
- 2008-03-21 JP JP2008074708A patent/JP2008259503A/ja not_active Withdrawn
-
2009
- 2009-10-15 JP JP2009238784A patent/JP5215275B2/ja not_active Expired - Fee Related
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