|
AT280356B
(de)
|
1968-03-06 |
1970-04-10 |
Telefonbau & Normalzeit Gmbh |
Schaltungsanordnung zur Steuerung des zur Zwischenspeicherung des Zeitwertes eines Signales verwendeten Kondensators eines Demodulators einer Zeitmultiplexanlage
|
|
US4376110A
(en)
|
1980-08-04 |
1983-03-08 |
Hybritech, Incorporated |
Immunometric assays using monoclonal antibodies
|
|
US4554101A
(en)
|
1981-01-09 |
1985-11-19 |
New York Blood Center, Inc. |
Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
|
|
CH660375A5
(it)
|
1983-02-08 |
1987-04-15 |
Sclavo Spa |
Procedimento per la produzione di proteine correlate alla tossina difterica.
|
|
CA1247080A
(en)
|
1983-03-08 |
1988-12-20 |
Commonwealth Serum Laboratories Commission |
Antigenically active amino acid sequences
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4650764A
(en)
|
1983-04-12 |
1987-03-17 |
Wisconsin Alumni Research Foundation |
Helper cell
|
|
US4668829A
(en)
*
|
1984-07-18 |
1987-05-26 |
University Patents, Inc. |
Ferroelectric smectic liquid crystals
|
|
JPS6147500A
(ja)
|
1984-08-15 |
1986-03-07 |
Res Dev Corp Of Japan |
キメラモノクロ−ナル抗体及びその製造法
|
|
EP0173494A3
(en)
|
1984-08-27 |
1987-11-25 |
The Board Of Trustees Of The Leland Stanford Junior University |
Chimeric receptors by dna splicing and expression
|
|
GB8422238D0
(en)
|
1984-09-03 |
1984-10-10 |
Neuberger M S |
Chimeric proteins
|
|
GB8424757D0
(en)
|
1984-10-01 |
1984-11-07 |
Pasteur Institut |
Retroviral vector
|
|
SE8405493D0
(sv)
|
1984-11-01 |
1984-11-01 |
Bror Morein |
Immunogent komplex samt sett for framstellning derav och anvendning derav som immunstimulerande medel
|
|
FR2573436B1
(fr)
|
1984-11-20 |
1989-02-17 |
Pasteur Institut |
Adn recombinant comportant une sequence nucleotidique codant pour un polypeptide determine sous le controle d'un promoteur d'adenovirus, vecteurs contenant cet adn recombinant, cellules eucaryotes transformees par cet adn recombinant, produits d'excretion de ces cellules transformees et leurs applications, notamment a la constitution de vaccins
|
|
JPS61134325A
(ja)
|
1984-12-04 |
1986-06-21 |
Teijin Ltd |
ハイブリツド抗体遺伝子の発現方法
|
|
US4797368A
(en)
|
1985-03-15 |
1989-01-10 |
The United States Of America As Represented By The Department Of Health And Human Services |
Adeno-associated virus as eukaryotic expression vector
|
|
US4666829A
(en)
|
1985-05-15 |
1987-05-19 |
University Of California |
Polypeptide marker for Alzheimer's disease and its use for diagnosis
|
|
EP0232262A4
(en)
|
1985-08-15 |
1989-09-19 |
Stauffer Chemical Co |
TRYPTOPHANE GENERATING MICROORGANISM.
|
|
US5078996A
(en)
|
1985-08-16 |
1992-01-07 |
Immunex Corporation |
Activation of macrophage tumoricidal activity by granulocyte-macrophage colony stimulating factor
|
|
US5139941A
(en)
|
1985-10-31 |
1992-08-18 |
University Of Florida Research Foundation, Inc. |
AAV transduction vectors
|
|
EP0247091B1
(en)
|
1985-11-01 |
1993-09-29 |
Xoma Corporation |
Modular assembly of antibody genes, antibodies prepared thereby and use
|
|
US4861719A
(en)
|
1986-04-25 |
1989-08-29 |
Fred Hutchinson Cancer Research Center |
DNA constructs for retrovirus packaging cell lines
|
|
US5514581A
(en)
*
|
1986-11-04 |
1996-05-07 |
Protein Polymer Technologies, Inc. |
Functional recombinantly prepared synthetic protein polymer
|
|
US4980289A
(en)
|
1987-04-27 |
1990-12-25 |
Wisconsin Alumni Research Foundation |
Promoter deficient retroviral vector
|
|
US5057540A
(en)
|
1987-05-29 |
1991-10-15 |
Cambridge Biotech Corporation |
Saponin adjuvant
|
|
JPH01125328A
(ja)
|
1987-07-30 |
1989-05-17 |
Centro Natl De Biopreparados |
髄膜炎菌ワクチン
|
|
JPH01144977A
(ja)
|
1987-11-30 |
1989-06-07 |
Agency Of Ind Science & Technol |
新規組換えプラスミドｐＴＰＧＩＦ２
|
|
WO1989007150A1
(en)
|
1988-02-05 |
1989-08-10 |
The Trustees Of Columbia University In The City Of |
Retroviral packaging cell lines and processes of using same
|
|
US4912094B1
(en)
|
1988-06-29 |
1994-02-15 |
Ribi Immunochem Research Inc. |
Modified lipopolysaccharides and process of preparation
|
|
JP3082204B2
(ja)
|
1988-09-01 |
2000-08-28 |
ホワイトヘッド・インスティチュート・フォー・バイオメディカル・リサーチ |
両栄養性および環境栄養性宿主域を持つ組換え体レトロウイルス
|
|
US7118757B1
(en)
*
|
1988-12-19 |
2006-10-10 |
Wyeth Holdings Corporation |
Meningococcal class 1 outer-membrane protein vaccine
|
|
US5124263A
(en)
|
1989-01-12 |
1992-06-23 |
Wisconsin Alumni Research Foundation |
Recombination resistant retroviral helper cell and products produced thereby
|
|
FI914241A7
(fi)
|
1989-03-09 |
1991-09-09 |
Praxis Biologics Inc |
Rokotteita ei-tyypitettävää Haemophilus influenzae-bakteereja vastaan
|
|
US5354844A
(en)
|
1989-03-16 |
1994-10-11 |
Boehringer Ingelheim International Gmbh |
Protein-polycation conjugates
|
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
|
WO1990014837A1
(en)
|
1989-05-25 |
1990-12-13 |
Chiron Corporation |
Adjuvant formulation comprising a submicron oil droplet emulsion
|
|
US5399346A
(en)
|
1989-06-14 |
1995-03-21 |
The United States Of America As Represented By The Department Of Health And Human Services |
Gene therapy
|
|
US5585362A
(en)
|
1989-08-22 |
1996-12-17 |
The Regents Of The University Of Michigan |
Adenovirus vectors for gene therapy
|
|
CA2039921A1
(en)
|
1990-04-16 |
1991-10-17 |
Xandra O. Breakefield |
Transfer and expression of gene sequences into central nervous system cells using herpes simplex virus mutants with deletions in genes for viral replication
|
|
US5264618A
(en)
|
1990-04-19 |
1993-11-23 |
Vical, Inc. |
Cationic lipids for intracellular delivery of biologically active molecules
|
|
AU7906691A
(en)
|
1990-05-23 |
1991-12-10 |
United States of America, as represented by the Secretary, U.S. Department of Commerce, The |
Adeno-associated virus (aav)-based eucaryotic vectors
|
|
EP0467714A1
(en)
|
1990-07-19 |
1992-01-22 |
Merck & Co. Inc. |
The class II protein of the outer membrane of neisseria meningitidis
|
|
JPH0453645U
(enExample)
*
|
1990-09-12 |
1992-05-07 |
|
|
|
KR100372934B1
(ko)
|
1990-09-25 |
2003-12-24 |
캔탑 파마슈티칼스 리서취 리미티드 |
형질 상보성 세포주에 의해 생성된 바이러스 결손 백신
|
|
US5173414A
(en)
|
1990-10-30 |
1992-12-22 |
Applied Immune Sciences, Inc. |
Production of recombinant adeno-associated virus vectors
|
|
IL101715A
(en)
|
1991-05-02 |
2005-06-19 |
Amgen Inc |
Recombinant dna-derived cholera toxin subunit analogs
|
|
WO1993007897A1
(en)
|
1991-10-21 |
1993-04-29 |
Medimmune, Inc. |
Bacterial expression vectors containing dna encoding secretion signals of lipoproteins
|
|
US5252479A
(en)
|
1991-11-08 |
1993-10-12 |
Research Corporation Technologies, Inc. |
Safe vector for gene therapy
|
|
IT1253009B
(it)
|
1991-12-31 |
1995-07-10 |
Sclavo Ricerca S R L |
Mutanti immunogenici detossificati della tossina colerica e della tossina lt, loro preparazione ed uso per la preparazione di vaccini
|
|
WO1993015115A1
(en)
*
|
1992-01-24 |
1993-08-05 |
Cornell Research Foundation, Inc. |
E. coli dna polymerase iii holoenzyme and subunits
|
|
JPH08503855A
(ja)
|
1992-12-03 |
1996-04-30 |
ジェンザイム・コーポレイション |
嚢胞性線維症に対する遺伝子治療
|
|
ES2231770T3
(es)
|
1993-03-05 |
2005-05-16 |
Wyeth Holdings Corporation |
Nuevos plasmidos para la produccion de proteina crm y toxina difterica.
|
|
WO1994021807A2
(en)
|
1993-03-19 |
1994-09-29 |
Cantab Pharmaceuticals Research Limited |
Defective mutant non-retroviral virus (e.g. hsv) as vaccine
|
|
DE69423383T2
(de)
|
1993-05-13 |
2000-08-24 |
American Cyanamid Co., Wayne |
Herstellung und Verwendungen von LOS-verminderten Aussenmembran-Proteinen von Gram-negativen Kokken
|
|
FR2705361B1
(fr)
|
1993-05-18 |
1995-08-04 |
Centre Nat Rech Scient |
Vecteurs viraux et utilisation en thérapie génique.
|
|
FR2705686B1
(fr)
|
1993-05-28 |
1995-08-18 |
Transgene Sa |
Nouveaux adénovirus défectifs et lignées de complémentation correspondantes.
|
|
CN1115414C
(zh)
|
1993-07-13 |
2003-07-23 |
罗纳-布朗克罗莱尔股份有限公司 |
用于基因治疗的病毒载体
|
|
US5439808A
(en)
*
|
1993-07-23 |
1995-08-08 |
North American Vaccine, Inc. |
Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
|
|
WO1995007358A1
(en)
|
1993-07-30 |
1995-03-16 |
University Of Medicine & Dentistry Of New Jersey |
Efficient gene transfer into primary lymphocytes
|
|
FR2708622B1
(fr)
|
1993-08-02 |
1997-04-18 |
Raymond Hamers |
Vecteur recombinant contenant une séquence d'un gène de lipoprotéine de structure pour l'expression de séquences de nucléotides.
|
|
US5550213A
(en)
*
|
1993-12-27 |
1996-08-27 |
Rutgers, The State University Of New Jersey |
Inhibitors of urokinase plasminogen activator
|
|
FR2714830B1
(fr)
|
1994-01-10 |
1996-03-22 |
Rhone Poulenc Rorer Sa |
Composition contenant des acides nucléiques, préparation et utilisations.
|
|
FR2715847B1
(fr)
|
1994-02-08 |
1996-04-12 |
Rhone Poulenc Rorer Sa |
Composition contenant des acides nucléiques, préparation et utilisations.
|
|
FI98045C
(fi)
|
1994-02-21 |
1997-04-10 |
Arto Remes |
Laite inkontinenssihoitoa varten
|
|
FR2716459B1
(fr)
|
1994-02-22 |
1996-05-10 |
Univ Paris Curie |
Système hôte-vecteur utilisable en thérapie génique.
|
|
AU2194895A
(en)
|
1994-03-25 |
1995-10-17 |
Uab Research Foundation, The |
Composition and methods for creating syngeneic recombinant virus-producing cells
|
|
US5739118A
(en)
|
1994-04-01 |
1998-04-14 |
Apollon, Inc. |
Compositions and methods for delivery of genetic material
|
|
EP0753069A1
(en)
|
1994-04-15 |
1997-01-15 |
Targeted Genetics Corporation |
Gene delivery fusion proteins
|
|
US5571515A
(en)
|
1994-04-18 |
1996-11-05 |
The Wistar Institute Of Anatomy & Biology |
Compositions and methods for use of IL-12 as an adjuvant
|
|
DK0710118T3
(da)
*
|
1994-04-20 |
1999-08-09 |
Us Army |
Vaccine mod infektioner med gram-negative bakterier
|
|
US6207646B1
(en)
|
1994-07-15 |
2001-03-27 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US5565204A
(en)
|
1994-08-24 |
1996-10-15 |
American Cyanamid Company |
Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections
|
|
US5837533A
(en)
|
1994-09-28 |
1998-11-17 |
American Home Products Corporation |
Complexes comprising a nucleic acid bound to a cationic polyamine having an endosome disruption agent
|
|
GB9422096D0
(en)
|
1994-11-02 |
1994-12-21 |
Biocine Spa |
Combined meningitis vaccine
|
|
FR2727679B1
(fr)
|
1994-12-05 |
1997-01-03 |
Rhone Poulenc Rorer Sa |
Nouveaux agents de transfection et leurs applications pharmaceutiques
|
|
BE1008978A5
(fr)
|
1994-12-27 |
1996-10-01 |
Solvay |
Adjuvants pour vaccins.
|
|
IL116816A
(en)
|
1995-01-20 |
2003-05-29 |
Rhone Poulenc Rorer Sa |
Cell for the production of a defective recombinant adenovirus or an adeno-associated virus and the various uses thereof
|
|
FR2730637B1
(fr)
|
1995-02-17 |
1997-03-28 |
Rhone Poulenc Rorer Sa |
Composition pharmaceutique contenant des acides nucleiques, et ses utilisations
|
|
IL117483A
(en)
|
1995-03-17 |
2008-03-20 |
Bernard Brodeur |
MENINGITIDIS NEISSERIA shell protein is resistant to proteinase K.
|
|
WO1996039036A1
(en)
|
1995-06-05 |
1996-12-12 |
The University Of Alabama At Birmingham Research Foundation |
Composition and methods for creating syngeneic recombinant virus-producing cells
|
|
CA2704354A1
(en)
*
|
1995-06-07 |
1996-12-19 |
Connaught Laboratories, Inc. |
Expression of lipoproteins
|
|
FR2741358B1
(fr)
|
1995-11-17 |
1998-01-02 |
Centre Nat Rech Scient |
Production de vecteurs retroviraux par l'intermediaire de vecteurs viraux a base de virus a adn
|
|
CU22559A1
(es)
*
|
1996-01-17 |
1999-05-03 |
Ct Ingenieria Genetica Biotech |
Sistema de expresión de antígenos heterologos en e. coli como proteínas de fusión
|
|
US6355255B1
(en)
|
1998-12-07 |
2002-03-12 |
Regents Of The University Of Minnesota |
Streptococcal C5a peptidase vaccine
|
|
US5846547A
(en)
|
1996-01-22 |
1998-12-08 |
Regents Of The University Of Minnesota |
Streptococcal C5a peptidase vaccine
|
|
US6048527A
(en)
|
1996-08-27 |
2000-04-11 |
Chiron Corporation |
Antibodies that define unique Meningococcal B epitopes and vaccine compositions
|
|
PT939647E
(pt)
|
1996-08-27 |
2002-04-29 |
Chiron Corp |
Glicpconjugados do serogrupo b de neisseria meningitidis e metodos de utilizacao dos mesmos
|
|
US6472518B1
(en)
|
1996-10-24 |
2002-10-29 |
Centers For Disease Control And Prevention, As Represented By The Secretary, Department Of Health And Human Services |
Invasion associated genes from Neisseria meningitidis serogroup B
|
|
GB9622159D0
(en)
|
1996-10-24 |
1996-12-18 |
Solvay Sociutu Anonyme |
Polyanionic polymers as adjuvants for mucosal immunization
|
|
GB9622660D0
(en)
|
1996-10-31 |
1997-01-08 |
Biocine Spa |
Immunogenic detoxified mutant toxin
|
|
US6113918A
(en)
|
1997-05-08 |
2000-09-05 |
Ribi Immunochem Research, Inc. |
Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors
|
|
DE19723095C2
(de)
|
1997-06-02 |
2001-08-23 |
Siemens Ag |
Bildrekonstruktionsverfahren für einen Computertomographen
|
|
DE69826124T3
(de)
|
1997-06-30 |
2007-10-11 |
Institut Gustave Roussy |
Verabreichung der nukleinsäure in den quergestreiften muskel
|
|
IL133709A0
(en)
|
1997-06-30 |
2001-04-30 |
Rhone Poulence Rorer S A |
Device for optimized electrotransfer of nucleic acid vectors to tissues in vivo
|
|
IL133708A0
(en)
|
1997-06-30 |
2001-04-30 |
Rhone Poulence Rorer S A |
Improved method for transferring nucleic acid into multicelled eukaryotic organism cells and combination thereof
|
|
CA2297072A1
(en)
*
|
1997-07-17 |
1999-01-28 |
Baxter Healthcare S.A. |
Immunogenic conjugates comprising a group b meningococcal porin and an h. influenzae polysaccharide
|
|
JPH1144977A
(ja)
|
1997-07-25 |
1999-02-16 |
Copyer Co Ltd |
画像形成装置
|
|
DK1007546T3
(da)
|
1997-08-27 |
2009-03-16 |
Novartis Vaccines & Diagnostic |
Molekylære mimetika af meningokok-B-epitoper
|
|
ID24325A
(id)
*
|
1997-08-29 |
2000-07-13 |
Dow Chemical Co |
Komposit polimer pengisi yang homogen
|
|
EP1900818A3
(en)
|
1997-11-06 |
2008-06-11 |
Novartis Vaccines and Diagnostics S.r.l. |
Neisserial antigens
|
|
TWI239847B
(en)
|
1997-12-02 |
2005-09-21 |
Elan Pharm Inc |
N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
|
|
WO1999036544A2
(en)
|
1998-01-14 |
1999-07-22 |
Chiron S.P.A. |
Neisseria meningitidis antigens
|
|
NZ525674A
(en)
*
|
1998-02-03 |
2005-01-28 |
Ct Disease Contr & Prevention |
Recombinant lipidated PsaA protein, methods of preparation and use
|
|
GB9806456D0
(en)
|
1998-03-25 |
1998-05-27 |
Smithkline Beecham Biolog |
Vaccine composition
|
|
GB9808734D0
(en)
|
1998-04-23 |
1998-06-24 |
Smithkline Beecham Biolog |
Novel compounds
|
|
GB9808932D0
(en)
|
1998-04-27 |
1998-06-24 |
Chiron Spa |
Polyepitope carrier protein
|
|
EP2261347A3
(en)
|
1998-05-01 |
2012-01-11 |
Novartis Vaccines and Diagnostics, Inc. |
Neisseria meningitidis antigens and compositions
|
|
JP5074644B2
(ja)
|
1998-05-29 |
2012-11-14 |
ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド |
組合わせの髄膜炎菌ｂ／ｃワクチン
|
|
JP4673974B2
(ja)
|
1998-09-30 |
2011-04-20 |
ワイス・ホールディングズ・コーポレイション |
アジュバントとしての変異コレラホロトキシン
|
|
DE69919754T2
(de)
*
|
1998-09-30 |
2005-09-01 |
Walter Reed Army Institute Of Research |
Verwendung von aufgereinigtem invaplex als impfstoff für gram-negativebakterien
|
|
MXPA01003557A
(es)
|
1998-10-09 |
2004-04-05 |
Chiron Corp |
Secuencias genomicas de neisseria y metodos para su uso.
|
|
US6660843B1
(en)
*
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
|
US6281337B1
(en)
|
1998-11-12 |
2001-08-28 |
Schering Corporation |
Methods for conversion of protein isoforms
|
|
CA2359486A1
(en)
|
1999-01-15 |
2000-07-20 |
Smithkline Beecham Biologicals S.A. |
Neisseria meningitidis polypeptide basb052
|
|
CA2360658A1
(en)
|
1999-01-22 |
2000-07-27 |
Smithkline Beecham Biologicals S.A. |
Neisseria meningitidis antigenic polypeptides, corresponding polynucleotides and protective antibodies
|
|
GB9902084D0
(en)
*
|
1999-01-29 |
1999-03-24 |
Smithkline Beecham Biolog |
Novel compounds
|
|
KR20010093290A
(ko)
|
1999-02-05 |
2001-10-27 |
폴락 돈나 엘. |
사람 파필로마바이러스 백신 제제
|
|
JP4812942B2
(ja)
|
1999-02-26 |
2011-11-09 |
ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル |
ＣＧモチーフを含むオリゴヌクレオチドを用いるＮｅｉｓｓｅｒｉａ抗原殺菌活性の増強
|
|
US6245568B1
(en)
|
1999-03-26 |
2001-06-12 |
Merck & Co., Inc. |
Human papilloma virus vaccine with disassembled and reassembled virus-like particles
|
|
US7115730B1
(en)
|
1999-04-27 |
2006-10-03 |
Chiron Srl |
Immunogenic detoxified mutant E. coli LT-A-toxin
|
|
CA2371032A1
(en)
|
1999-04-30 |
2000-11-09 |
Chiron Corporation |
Neisseria genomic sequences and methods of their use
|
|
CA2372235A1
(en)
|
1999-04-30 |
2000-11-09 |
Rino Rappuoli |
Conserved neisserial antigens
|
|
AU783894B2
(en)
*
|
1999-05-19 |
2005-12-22 |
Novartis Vaccines And Diagnostics S.R.L. |
Combination neisserial compositions
|
|
GB9911683D0
(en)
|
1999-05-19 |
1999-07-21 |
Chiron Spa |
Antigenic peptides
|
|
GB9916529D0
(en)
|
1999-07-14 |
1999-09-15 |
Chiron Spa |
Antigenic peptides
|
|
GB9918319D0
(en)
*
|
1999-08-03 |
1999-10-06 |
Smithkline Beecham Biolog |
Vaccine composition
|
|
US7384640B1
(en)
|
1999-09-30 |
2008-06-10 |
Wyeth Holdings Corporation |
Mutant cholera holotoxin as an adjuvant
|
|
EP1226253A2
(en)
|
1999-10-29 |
2002-07-31 |
Chiron S.P.A. |
Neisserial antigenic peptides
|
|
EP1234039A2
(en)
|
1999-11-29 |
2002-08-28 |
Chiron Spa |
85kDa NEISSERIAL ANTIGEN
|
|
GB9928196D0
(en)
*
|
1999-11-29 |
2000-01-26 |
Chiron Spa |
Combinations of B, C and other antigens
|
|
DK1233784T3
(da)
|
1999-12-02 |
2008-09-01 |
Novartis Vaccines & Diagnostic |
Præparater og fremgangsmåder til stabilisering af biologiske molekyler efter lyofilisering
|
|
CA2871789C
(en)
*
|
2000-01-17 |
2017-04-04 |
Novartis Vaccines And Diagnostics S.R.L. |
Outer membrane vesicle (omv) vaccine comprising n. meningitidis serogroup b outer membrane proteins
|
|
DK1947187T5
(da)
|
2000-02-28 |
2011-10-24 |
Novartis Vaccines & Diagnostic |
Hybrid ekspression af neisserial-proteiner
|
|
WO2001093905A1
(en)
|
2000-06-08 |
2001-12-13 |
Intercell Biomedizinische Forschungs- Und Entwicklungs Ag |
Immunostimulatory oligodeoxynucleotides
|
|
AT410635B
(de)
|
2000-10-18 |
2003-06-25 |
Cistem Biotechnologies Gmbh |
Vakzin-zusammensetzung
|
|
PT2332581E
(pt)
|
2001-01-23 |
2015-10-16 |
Sanofi Pasteur Inc |
Vacina meningocócica tri- ou tetravalente de conjugados de polissacárido e crm-197
|
|
GB0103424D0
(en)
|
2001-02-12 |
2001-03-28 |
Chiron Spa |
Gonococcus proteins
|
|
WO2002079246A2
(en)
|
2001-03-30 |
2002-10-10 |
Geneprot, Inc. |
Human arginine-rich protein-related compositions
|
|
US6942802B2
(en)
|
2001-04-13 |
2005-09-13 |
Wyeth Holdings Corporation |
Removal of bacterial endotoxin in a protein solution by immobilized metal affinity chromatography
|
|
CN1306956C
(zh)
|
2001-04-17 |
2007-03-28 |
希龙公司 |
诱导功能活性抗体的脑膜炎球菌b抗原表位的分子模拟物
|
|
CN1977971A
(zh)
|
2001-06-07 |
2007-06-13 |
惠氏控股有限公司 |
作为佐剂的霍乱全毒素的突变体形式
|
|
IL159209A0
(en)
|
2001-06-07 |
2004-06-01 |
Wyeth Corp |
Mutant forms of cholera holotoxin as an adjuvant
|
|
GB0115176D0
(en)
|
2001-06-20 |
2001-08-15 |
Chiron Spa |
Capular polysaccharide solubilisation and combination vaccines
|
|
EP1409013B1
(en)
|
2001-07-26 |
2009-11-18 |
Novartis Vaccines and Diagnostics S.r.l. |
Vaccines comprising aluminium adjuvants and histidine
|
|
GB0121591D0
(en)
|
2001-09-06 |
2001-10-24 |
Chiron Spa |
Hybrid and tandem expression of neisserial proteins
|
|
EP1436385A4
(en)
|
2001-09-14 |
2005-12-14 |
Invitrogen Corp |
DNA POLYMERASES AND MUTANTS CORRESPONDING
|
|
MX339524B
(es)
*
|
2001-10-11 |
2016-05-30 |
Wyeth Corp |
Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
|
|
GB0129007D0
(en)
|
2001-12-04 |
2002-01-23 |
Chiron Spa |
Adjuvanted antigenic meningococcal compositions
|
|
DK1777236T3
(en)
|
2002-03-26 |
2017-02-27 |
Glaxosmithkline Biologicals Sa |
MODIFIED SUCCARIDES WHICH IMPROVED WATER STABILITY FOR USE AS A MEDICINE
|
|
GB0302218D0
(en)
|
2003-01-30 |
2003-03-05 |
Chiron Sri |
Vaccine formulation & Mucosal delivery
|
|
DE60328481D1
(de)
|
2002-05-14 |
2009-09-03 |
Novartis Vaccines & Diagnostic |
Schleimhautapplizierter impfstoff, der das adjuvanz chitosan und menigokokkenantigene enthält
|
|
CN1816350B
(zh)
|
2002-05-14 |
2010-11-10 |
莱顿大学 |
带有几丁聚糖佐剂和/或脑膜炎抗原的粘膜疫苗
|
|
US7785608B2
(en)
*
|
2002-08-30 |
2010-08-31 |
Wyeth Holdings Corporation |
Immunogenic compositions for the prevention and treatment of meningococcal disease
|
|
GB0220194D0
(en)
|
2002-08-30 |
2002-10-09 |
Chiron Spa |
Improved vesicles
|
|
GB0220198D0
(en)
|
2002-08-30 |
2002-10-09 |
Chiron Spa |
Modified saccharides,conjugates thereof and their manufacture
|
|
CN1809380B
(zh)
|
2002-10-11 |
2010-05-12 |
启龙有限公司 |
广泛防御高毒性脑膜炎球菌谱系的多肽-疫苗
|
|
WO2004046177A2
(en)
|
2002-11-15 |
2004-06-03 |
Chiron Srl |
Unexpected surface proteins in neisseria meningitidis
|
|
GB0227346D0
(en)
|
2002-11-22 |
2002-12-31 |
Chiron Spa |
741
|
|
EP1590459A2
(en)
|
2003-01-15 |
2005-11-02 |
Wyeth Holdings Corporation |
Methods for increasing neisseria protein expression and compositions thereof
|
|
ES2461350T3
(es)
|
2003-01-30 |
2014-05-19 |
Novartis Ag |
Vacunas inyectables contra múltiples serogrupos de meningococos
|
|
US20060251675A1
(en)
|
2003-03-17 |
2006-11-09 |
Michael Hagen |
Mutant cholera holotoxin as an adjuvant and an antigen carrier protein
|
|
BRPI0409459A
(pt)
|
2003-04-16 |
2006-05-02 |
Wyeth Corp |
novas composições imunogênicas para a prevenção e tratamento de doença meningocócica
|
|
JP5557415B2
(ja)
|
2003-06-02 |
2014-07-23 |
ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド |
吸着させたトキソイドおよび多糖類含有抗原を含む微粒子に基づく免疫原性組成物
|
|
CA2530434A1
(en)
|
2003-06-23 |
2005-01-06 |
Aventis Pasteur, Inc. |
Immunization method against neisseria meningitidis serogroups a and c
|
|
GB0316560D0
(en)
|
2003-07-15 |
2003-08-20 |
Chiron Srl |
Vesicle filtration
|
|
NZ546430A
(en)
|
2003-10-02 |
2009-04-30 |
Novartis Vaccines & Diagnostic |
Liquid vaccines for multiple meningococcal serogroups
|
|
GB0323103D0
(en)
|
2003-10-02 |
2003-11-05 |
Chiron Srl |
De-acetylated saccharides
|
|
CA2551896A1
(en)
|
2003-12-30 |
2005-07-21 |
Wyeth |
Formulations of hydrophobic proteins in an immunogenic composition having improved tolerability
|
|
GB0406013D0
(en)
|
2004-03-17 |
2004-04-21 |
Chiron Srl |
Analysis of saccharide vaccines without interference
|
|
GB0408977D0
(en)
|
2004-04-22 |
2004-05-26 |
Chiron Srl |
Immunising against meningococcal serogroup Y using proteins
|
|
GB0408978D0
(en)
|
2004-04-22 |
2004-05-26 |
Chiron Srl |
Meningococcal fermentation for preparing conjugate vaccines
|
|
GB0500787D0
(en)
|
2005-01-14 |
2005-02-23 |
Chiron Srl |
Integration of meningococcal conjugate vaccination
|
|
GB0409745D0
(en)
|
2004-04-30 |
2004-06-09 |
Chiron Srl |
Compositions including unconjugated carrier proteins
|
|
US9402915B2
(en)
|
2004-04-30 |
2016-08-02 |
Glaxosmithkline Biologicals Sa |
Integration of meningococcal conjugate vaccination
|
|
GB0410220D0
(en)
|
2004-05-07 |
2004-06-09 |
Kirkham Lea Ann |
Mutant pneumolysin proteins
|
|
GB0411387D0
(en)
|
2004-05-21 |
2004-06-23 |
Chiron Srl |
Analysis of saccharide length
|
|
GB0413868D0
(en)
|
2004-06-21 |
2004-07-21 |
Chiron Srl |
Dimensional anlaysis of saccharide conjugates
|
|
DE602005025647D1
(de)
|
2004-07-23 |
2011-02-10 |
Novartis Vaccines & Diagnostic |
Polypeptide für die oligomerisierung von antigenen
|
|
GB0419408D0
(en)
|
2004-09-01 |
2004-10-06 |
Chiron Srl |
741 chimeric polypeptides
|
|
GB0419846D0
(en)
|
2004-09-07 |
2004-10-13 |
Chiron Srl |
Vaccine adjuvants for saccharides
|
|
GB0424092D0
(en)
|
2004-10-29 |
2004-12-01 |
Chiron Srl |
Immunogenic bacterial vesicles with outer membrane proteins
|
|
GB0428394D0
(en)
|
2004-12-24 |
2005-02-02 |
Chiron Srl |
Saccharide conjugate vaccines
|
|
LT2682126T
(lt)
|
2005-01-27 |
2017-02-27 |
Children`s Hospital & Research Center at Oakland |
Gna1870 pagrindu gaminamos pūslelių pavidalo vakcinos, skirtos plataus spektro apsaugai nuo neisseria meningitidis sukeltų ligų
|
|
US20070014842A1
(en)
|
2005-03-07 |
2007-01-18 |
Denis Martin |
Pharmaceutical liposomal compositions
|
|
BRPI0611447A2
(pt)
|
2005-05-06 |
2010-09-08 |
Stockholm University |
imunógenos para vacinas contra meningite a
|
|
LT2351578T
(lt)
|
2005-06-27 |
2017-04-10 |
Glaxosmithkline Biologicals S.A. |
Vakcinų gavimo būdas
|
|
EP2308504A3
(en)
|
2005-09-01 |
2011-11-30 |
Novartis Vaccines and Diagnostics GmbH |
Multiple vaccines including serogroup C meningococcus
|
|
ES2407683T3
(es)
|
2005-09-05 |
2013-06-13 |
Glaxosmithkline Biologicals S.A. |
Ensayo bactericida del suero para antisuero específico de N.
Meningitidis
|
|
GB0524066D0
(en)
|
2005-11-25 |
2006-01-04 |
Chiron Srl |
741 ii
|
|
WO2007071786A2
(en)
|
2005-12-23 |
2007-06-28 |
Glaxosmithkline Biologicals Sa |
Conjugate vaccines
|
|
ES2383209T3
(es)
|
2006-03-22 |
2012-06-19 |
Novartis Ag |
Regímenes para la inmunización con conjugados meningococicos
|
|
WO2007127668A2
(en)
|
2006-04-26 |
2007-11-08 |
Wyeth |
Novel processes for coating container means which inhibit precipitation of polysaccharide-protein conjugate formulations
|
|
TW200806315A
(en)
|
2006-04-26 |
2008-02-01 |
Wyeth Corp |
Novel formulations which stabilize and inhibit precipitation of immunogenic compositions
|
|
DE602007003596D1
(de)
|
2006-06-12 |
2010-01-14 |
Glaxosmithkline Biolog Sa |
Impfstoff
|
|
GB0612854D0
(en)
|
2006-06-28 |
2006-08-09 |
Novartis Ag |
Saccharide analysis
|
|
CN101479293A
(zh)
|
2006-06-29 |
2009-07-08 |
诺华有限公司 |
脑膜炎奈瑟球菌多肽
|
|
SG174013A1
(en)
|
2006-07-27 |
2011-09-29 |
Wyeth Corp |
High-cell density fed-batch fermentation process for producing recombinant protein
|
|
AR064642A1
(es)
*
|
2006-12-22 |
2009-04-15 |
Wyeth Corp |
Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
|
|
GB0700562D0
(en)
|
2007-01-11 |
2007-02-21 |
Novartis Vaccines & Diagnostic |
Modified Saccharides
|
|
JP5637848B2
(ja)
|
2007-06-04 |
2014-12-10 |
ノバルティス アーゲー |
髄膜炎ワクチンの製剤化
|
|
GB0713880D0
(en)
|
2007-07-17 |
2007-08-29 |
Novartis Ag |
Conjugate purification
|
|
GB0714963D0
(en)
|
2007-08-01 |
2007-09-12 |
Novartis Ag |
Compositions comprising antigens
|
|
EP2185576A4
(en)
*
|
2007-08-02 |
2011-01-12 |
Childrens Hosp & Res Ct Oak |
FHBP- AND LPXL1-BASED VESICIUM VACCINES FOR BROADBAND PROTECTION AGAINST NEISSERIA MENINGITIDIS-RELATED DISEASES
|
|
BR122016015627A2
(pt)
|
2007-10-19 |
2018-10-30 |
Novartis Ag |
kit, composição antigênica liofilizada e método para preparação de uma composição imunogênica
|
|
EP2886551A3
(en)
|
2008-02-21 |
2015-09-23 |
Novartis AG |
Meningococcal fhbp polypeptides
|
|
ES2615390T3
(es)
|
2008-03-05 |
2017-06-06 |
Sanofi Pasteur |
Proceso para estabilizar una composición de vacuna que contiene adyuvante
|
|
EP2631245A1
(en)
|
2008-03-10 |
2013-08-28 |
Children's Hospital & Research Center at Oakland |
Chimeric factor H binding proteins (fHBP) containing a heterologous B domain and methods of use
|
|
WO2009143168A2
(en)
|
2008-05-19 |
2009-11-26 |
Novartis Ag |
Vaccine assays
|
|
RU2477145C2
(ru)
|
2008-05-30 |
2013-03-10 |
ДЗЕ Ю.Эс.Эй., ЭС РЕПРЕЗЕНТЕД БАЙ ДЗЕ СЕКРЕТАРИ ОФ ДЗЕ АРМИ, ОН БЕХАФ ОФ УОЛТЕР РИД АРМИ |
Мультивалентная вакцина из нативных везикул наружной мембраны менингококков, способы ее получения и применения
|
|
WO2010027872A1
(en)
|
2008-08-27 |
2010-03-11 |
Children's Hospital & Research Center At Oakland |
Complement factor h-based assays for serum bactericidal activity against neisseria meningitidis
|
|
CA2733943A1
(en)
|
2008-09-03 |
2010-03-11 |
Children's Hospital & Research Center At Oakland |
Peptides presenting an epitope of an a domain of factor h binding protein and methods of use
|
|
IT1394288B1
(it)
|
2008-09-12 |
2012-06-06 |
Novartis Vaccines & Diagnostic |
Immunogeni di proteine che legano il fattore h.
|
|
KR101593285B1
(ko)
|
2008-10-29 |
2016-02-11 |
아블린쓰 엔.브이. |
단일 도메인 항원 결합 분자의 제형
|
|
GB0822634D0
(en)
|
2008-12-11 |
2009-01-21 |
Novartis Ag |
Meningitis vaccines
|
|
JP5410084B2
(ja)
*
|
2008-12-15 |
2014-02-05 |
川上産業株式会社 |
梱包箱及び箱状芯材
|
|
WO2010070453A2
(en)
|
2008-12-17 |
2010-06-24 |
Novartis Ag |
Meningococcal vaccines including hemoglobin receptor
|
|
PL2411048T3
(pl)
*
|
2009-03-24 |
2020-11-16 |
Glaxosmithkline Biologicals Sa |
Adjuwantowe meningokokowe białko wiążące czynnik h
|
|
US20120064103A1
(en)
|
2009-03-24 |
2012-03-15 |
Novartis Ag |
Combinations of meningococcal factor h binding protein and pneumococcal saccharide conjugates
|
|
JP5883380B2
(ja)
|
2009-04-30 |
2016-03-15 |
チルドレンズ ホスピタル アンド リサーチ センター アット オークランド |
キメラ因子ｈ結合タンパク質（ｆｈｂｐ）およびその使用方法
|
|
US9365885B2
(en)
|
2009-06-16 |
2016-06-14 |
Puiying Annie Mak |
High-throughput complement-mediated antibody-dependent and opsonic bactericidal assays
|
|
JP2013502918A
(ja)
|
2009-08-27 |
2013-01-31 |
ノバルティス アーゲー |
髄膜炎菌ｆＨＢＰ配列を含むハイブリッドポリペプチド
|
|
IT1395574B1
(it)
|
2009-09-14 |
2012-10-16 |
Guala Dispensing Spa |
Dispositivo di erogazione
|
|
US20130022639A1
(en)
|
2009-09-30 |
2013-01-24 |
Novartis Ag |
Expression of meningococcal fhbp polypeptides
|
|
GB0917647D0
(en)
|
2009-10-08 |
2009-11-25 |
Glaxosmithkline Biolog Sa |
Expression system
|
|
JP3158225U
(ja)
*
|
2009-10-22 |
2010-03-25 |
王 文燦 |
折畳める物置袋
|
|
BR112012010531A2
(pt)
|
2009-10-27 |
2019-09-24 |
Novartis Ag |
"polipeptídeos de modificação meningocócica fhbp"
|
|
US9173954B2
(en)
|
2009-12-30 |
2015-11-03 |
Glaxosmithkline Biologicals Sa |
Polysaccharide immunogens conjugated to E. coli carrier proteins
|
|
GB201003922D0
(en)
|
2010-03-09 |
2010-04-21 |
Glaxosmithkline Biolog Sa |
Conjugation process
|
|
EP2544714A1
(en)
|
2010-03-10 |
2013-01-16 |
GlaxoSmithKline Biologicals S.A. |
Vaccine composition
|
|
WO2012020326A1
(en)
|
2010-03-18 |
2012-02-16 |
Novartis Ag |
Adjuvanted vaccines for serogroup b meningococcus
|
|
WO2011126863A1
(en)
|
2010-03-30 |
2011-10-13 |
Children's Hospital & Research Center Oakland |
Factor h binding proteins (fhbp) with altered properties and methods of use thereof
|
|
CA2803239A1
(en)
|
2010-06-25 |
2011-12-29 |
Novartis Ag |
Combinations of meningococcal factor h binding proteins
|
|
RU2580620C2
(ru)
|
2010-08-23 |
2016-04-10 |
ВАЙЕТ ЭлЭлСи |
СТАБИЛЬНЫЕ КОМПОЗИЦИИ АНТИГЕНОВ Neisseria meningitidis rLP2086
|
|
EP2612148B1
(en)
|
2010-09-04 |
2019-06-12 |
GlaxoSmithKline Biologicals SA |
Bactericidal antibody assays to assess immunogenicity and potency of meningococcal capsular saccharide vaccines
|
|
GB201015132D0
(en)
|
2010-09-10 |
2010-10-27 |
Univ Bristol |
Vaccine composition
|
|
BR112013005626B1
(pt)
|
2010-09-10 |
2022-07-26 |
Glaxosmithkline Biologicals Sa |
Meningococo, processo para a preparação de uma cepa meningocócica, vesículas de membrana externa, composição farmacêutica imunogênica, e, uso de uma composição
|
|
US20120070457A1
(en)
|
2010-09-10 |
2012-03-22 |
J. Craig Venter Institute, Inc. |
Polypeptides from neisseria meningitidis
|
|
WO2012032489A1
(en)
|
2010-09-10 |
2012-03-15 |
Wyeth Llc |
Non-lipidated variants of neisseria meningitidis orf2086 antigens
|
|
GB201101665D0
(en)
|
2011-01-31 |
2011-03-16 |
Novartis Ag |
Immunogenic compositions
|
|
US20140112950A1
(en)
|
2011-03-02 |
2014-04-24 |
Manmohan Singh |
Combination vaccines with lower doses of antigen and/or adjuvant
|
|
US9181308B2
(en)
|
2011-03-28 |
2015-11-10 |
St. Jude Children's Research Hospital |
Methods and compositions employing immunogenic fusion proteins
|
|
SA115360586B1
(ar)
|
2012-03-09 |
2017-04-12 |
فايزر انك |
تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
|
|
CA2865745C
(en)
|
2012-03-09 |
2018-01-09 |
Pfizer Inc. |
Neisseria meningitidis compositions and methods thereof
|
|
US9802987B2
(en)
|
2013-03-08 |
2017-10-31 |
Pfizer Inc. |
Immunogenic fusion polypeptides
|
|
US9965924B2
(en)
|
2013-07-15 |
2018-05-08 |
Ahmnon D. Moskowitz |
Methods, systems, and apparatus for playing multi-zone 21
|
|
RU2662968C2
(ru)
|
2013-09-08 |
2018-07-31 |
Пфайзер Инк. |
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|
|
AU2016221318B2
(en)
|
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|
|
US10183070B2
(en)
|
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|