JO3600B1 - لقاحات مؤتلفة ل fmdv و استخداماتها - Google Patents

لقاحات مؤتلفة ل fmdv و استخداماتها

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Publication number
JO3600B1
JO3600B1 JOP/2015/0240A JOP20150240A JO3600B1 JO 3600 B1 JO3600 B1 JO 3600B1 JO P20150240 A JOP20150240 A JO P20150240A JO 3600 B1 JO3600 B1 JO 3600B1
Authority
JO
Jordan
Prior art keywords
fmdv
recombinant vaccines
vaccine
fmdv recombinant
vaccines
Prior art date
Application number
JOP/2015/0240A
Other languages
English (en)
Inventor
Audonnet Jean-Christophe
Widner Justin
Hannas-Djebbara Zahia
Mebatsion Teshome
Chiang Yu-Wei
Original Assignee
Merial Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Inc filed Critical Merial Inc
Application granted granted Critical
Publication of JO3600B1 publication Critical patent/JO3600B1/ar

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/125Picornaviridae, e.g. calicivirus
    • A61K39/135Foot- and mouth-disease virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5258Virus-like particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10041Use of virus, viral particle or viral elements as a vector
    • C12N2710/10043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/14011Baculoviridae
    • C12N2710/14041Use of virus, viral particle or viral elements as a vector
    • C12N2710/14043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vectore
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32111Aphthovirus, e.g. footandmouth disease virus
    • C12N2770/32123Virus like particles [VLP]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32111Aphthovirus, e.g. footandmouth disease virus
    • C12N2770/32134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

يشتمل الاختراع الحالي على لقاحات أو تركيبات FMDV. قد يكون اللقاح أو التركيبة لقاحًا أو تركيبة تحتوي على مستضدات الحمى القلاعية. يشتمل الاختراع أيضًا على نواقل مؤتلفة ترميز وتعبر عن مستضدات FMDV أو الحلقية أو المستضدات المناعية التي يمكن استخدامها لحماية الحيوانات ، وخاصة الأفران أو الأبقار أو الأغنام أو الخنازير ضد فيروس الحمى القلاعية.
JOP/2015/0240A 2014-09-23 2015-09-28 لقاحات مؤتلفة ل fmdv و استخداماتها JO3600B1 (ar)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462054073P 2014-09-23 2014-09-23

Publications (1)

Publication Number Publication Date
JO3600B1 true JO3600B1 (ar) 2020-07-05

Family

ID=54256845

Family Applications (1)

Application Number Title Priority Date Filing Date
JOP/2015/0240A JO3600B1 (ar) 2014-09-23 2015-09-28 لقاحات مؤتلفة ل fmdv و استخداماتها

Country Status (17)

Country Link
US (1) US10010605B2 (ar)
EP (1) EP3197486A1 (ar)
JP (1) JP6931327B2 (ar)
KR (1) KR102526219B1 (ar)
CN (1) CN107073100B (ar)
AP (1) AP2017009834A0 (ar)
AR (1) AR102006A1 (ar)
AU (2) AU2015320673B2 (ar)
BR (1) BR112017005833A8 (ar)
CA (1) CA2962225A1 (ar)
JO (1) JO3600B1 (ar)
MA (1) MA40151B2 (ar)
MX (1) MX2017003712A (ar)
RU (1) RU2745373C2 (ar)
TW (1) TWI733653B (ar)
WO (1) WO2016049209A1 (ar)
ZA (1) ZA201701851B (ar)

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US9913891B2 (en) 2015-11-23 2018-03-13 Merial Inc. FMDV and E2 fusion proteins and uses thereof
TWI760322B (zh) 2016-01-29 2022-04-11 美商百靈佳殷格翰動物保健美國有限公司 重組腺病毒載體裝載之fmdv疫苗及其用途
US10172933B2 (en) 2016-10-31 2019-01-08 The United States Of America, As Represented By The Secretary Of Agriculture Mosaic vaccines for serotype a foot-and-mouth disease virus
KR20200027479A (ko) * 2017-07-12 2020-03-12 베링거 인겔하임 애니멀 헬스 유에스에이 인크. 세네카바이러스 a 면역원성 조성물 및 이의 방법
CN108103034B (zh) * 2017-12-15 2022-06-24 云南农业大学动物医学院 同时表达A型、O型和Asia-1型口蹄疫病毒VP1基因重组腺病毒、构建方法及应用
CN108530522B (zh) * 2018-03-14 2021-09-17 中华人民共和国汕头海关 一种重组的OmpK多表位多肽、构建方法及其应用
CN110467654B (zh) * 2018-05-11 2022-08-09 普莱柯生物工程股份有限公司 口蹄疫病毒样颗粒抗原、其制备的疫苗组合物及其制备方法和应用
CN111233984B (zh) * 2018-11-29 2022-08-12 普莱柯生物工程股份有限公司 一种o型口蹄疫病毒样颗粒抗原、及其疫苗组合物、制备方法和应用
US20220096620A1 (en) * 2019-01-15 2022-03-31 Pulike Biological Engineering, Inc. Foot-and-mouth disease virus-like particle antigen, and vaccine composition, preparation method, and application thereof
KR102672787B1 (ko) * 2019-06-28 2024-06-05 (주)플럼라인생명과학 구제역 바이러스 백신 조성물
JP2023549461A (ja) * 2020-10-22 2023-11-27 インターベット インターナショナル ベー. フェー. バキュロウイルス発現ベクター
US20230149528A1 (en) * 2021-08-18 2023-05-18 The United States Of America, As Represented By The Secretary Of Agriculture Development of mosaic vaccines against foot and mouth disease virus serotype o
EP4387663A1 (en) * 2021-08-20 2024-06-26 Intervet International B.V. Method of producing a foot and mouth disease virus virus-like particle
KR20240049581A (ko) * 2021-08-20 2024-04-16 인터벳 인터내셔널 비.브이. 구제역 바이러스 바이러스-유사 입자의 생성 방법
EP4387664A1 (en) * 2021-08-20 2024-06-26 Intervet International B.V. Fmdv virus-like particle with stabilizing mutation
WO2023020738A1 (en) * 2021-08-20 2023-02-23 The Pirbright Institute Fmdv virus-like particle with double stabilizing mutation
KR102513632B1 (ko) * 2021-11-30 2023-03-28 주식회사 왓슨알앤디 구제역 바이러스 유사 입자를 생산하기 위한 백신 플랫폼
US12036318B2 (en) * 2022-02-16 2024-07-16 Chemical & Schutz High Performance Lubricants, S.A. De C.V. Self-emulsionable mineral oil as a vehicle in vaccines for poultry
KR20240087552A (ko) 2022-11-23 2024-06-19 주식회사 옵티팜 구제역 바이러스 유사 입자 또는 나노입자 생산을 위한 재조합 발현 벡터 및 이를 이용한 백신 조성물
WO2024112115A1 (ko) * 2022-11-23 2024-05-30 주식회사 옵티팜 구제역 바이러스 유사 입자 또는 나노입자 생산을 위한 재조합 발현 벡터 및 이를 이용한 백신 조성물
CN117210501B (zh) * 2023-09-13 2024-06-07 中国农业科学院兰州兽医研究所 口蹄疫病毒2b蛋白免疫抑制位点突变的重组口蹄疫病毒株的构建
CN117304277B (zh) * 2023-09-26 2024-03-08 中国农业科学院兰州兽医研究所 一种o型口蹄疫病毒vp4蛋白t细胞表位多肽及其应用

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Also Published As

Publication number Publication date
RU2745373C2 (ru) 2021-03-24
US20160220659A1 (en) 2016-08-04
WO2016049209A1 (en) 2016-03-31
MX2017003712A (es) 2017-06-28
JP2017530124A (ja) 2017-10-12
CA2962225A1 (en) 2016-03-31
AU2019210537A1 (en) 2019-08-15
MA40151A1 (fr) 2018-01-31
ZA201701851B (en) 2018-05-30
JP6931327B2 (ja) 2021-09-01
AP2017009834A0 (en) 2017-03-31
CN107073100B (zh) 2021-02-26
EP3197486A1 (en) 2017-08-02
BR112017005833A8 (pt) 2023-02-14
KR20170058430A (ko) 2017-05-26
MA40151B2 (fr) 2022-12-30
RU2017113571A3 (ar) 2019-04-22
TW201625297A (zh) 2016-07-16
BR112017005833A2 (pt) 2018-02-27
AR102006A1 (es) 2017-01-25
RU2017113571A (ru) 2018-10-26
AU2015320673B2 (en) 2019-05-02
KR102526219B1 (ko) 2023-04-26
US10010605B2 (en) 2018-07-03
CN107073100A (zh) 2017-08-18
AU2015320673A1 (en) 2017-05-11
TWI733653B (zh) 2021-07-21

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