BRPI0512421B8 - Recombinantes de avipox expressando genes do vírus da doença febre aftosa - Google Patents

Recombinantes de avipox expressando genes do vírus da doença febre aftosa

Info

Publication number
BRPI0512421B8
BRPI0512421B8 BRPI0512421A BRPI0512421A BRPI0512421B8 BR PI0512421 B8 BRPI0512421 B8 BR PI0512421B8 BR PI0512421 A BRPI0512421 A BR PI0512421A BR PI0512421 A BRPI0512421 A BR PI0512421A BR PI0512421 B8 BRPI0512421 B8 BR PI0512421B8
Authority
BR
Brazil
Prior art keywords
disease virus
fmd
avipox
virus genes
recombinants expressing
Prior art date
Application number
BRPI0512421A
Other languages
English (en)
Inventor
Nordgren Robert
May Loosmore Sheena
Francis Audonnet Jean-Christophe
J Grubman Marvin
Original Assignee
Merial Ltd
Merial Inc
Boehringer Ingelheim Animal Health Usa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Ltd, Merial Inc, Boehringer Ingelheim Animal Health Usa Inc filed Critical Merial Ltd
Publication of BRPI0512421A publication Critical patent/BRPI0512421A/pt
Publication of BRPI0512421B1 publication Critical patent/BRPI0512421B1/pt
Publication of BRPI0512421B8 publication Critical patent/BRPI0512421B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/125—Picornaviridae, e.g. calicivirus
    • A61K39/135—Foot- and mouth-disease virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/24043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32111—Aphthovirus, e.g. footandmouth disease virus
    • C12N2770/32134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

RECOMBINANTES DE AVIPOX EXPRESSANDO GENES DO VÍRUS DA DOENÇA FEBRE AFTOSA. A presente invenção refere-se a vetores poxvirais modificados e a métodos de fabricação e uso dos mesmos. Em particular, a invenção refe-re-se a avipox recombinante que expressa produtos de gene do vírus da doença febre aftosa (FMDV) e a composições ou vacinas que elicitam resposta imune direcionada aos produtos de gene de FMDV e que podem conferir imunidade protetora contra infecção por FMDV.
BRPI0512421A 2004-06-25 2005-04-20 Recombinantes de avipox expressando genes do vírus da doença febre aftosa BRPI0512421B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56378604P 2004-06-25 2004-06-25
US60/563,786 2004-06-25
US2006073431 2006-07-13

Publications (3)

Publication Number Publication Date
BRPI0512421A BRPI0512421A (pt) 2008-03-04
BRPI0512421B1 BRPI0512421B1 (pt) 2014-09-09
BRPI0512421B8 true BRPI0512421B8 (pt) 2022-06-28

Family

ID=36648298

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0512421A BRPI0512421B8 (pt) 2004-06-25 2005-04-20 Recombinantes de avipox expressando genes do vírus da doença febre aftosa

Country Status (9)

Country Link
US (2) US7527960B2 (pt)
EP (1) EP1773387B1 (pt)
BR (1) BRPI0512421B8 (pt)
CA (1) CA2571560C (pt)
DK (1) DK1773387T3 (pt)
EC (1) ECSP077196A (pt)
ES (1) ES2424847T3 (pt)
PL (1) PL1773387T3 (pt)
WO (1) WO2006073431A2 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112012010357B1 (pt) * 2009-11-02 2022-05-24 Inovio Pharmaceuticals, Inc. Proteínas de consenso de vírus de doença de febre aftosa (fmdv), sequências de codificação para as mesmas e vacinas feitas a partir das mesmas
WO2011112945A2 (en) * 2010-03-12 2011-09-15 Merial Limited Foot and mouth disease virus recombinant vaccines and uses thereof
CN101948510B (zh) * 2010-09-10 2012-08-29 中国人民解放军第二军医大学 一种o型口蹄疫病毒vp2抗原表位的分子模拟肽及其用途
WO2013123242A1 (en) 2012-02-14 2013-08-22 Merial Limited Recombinant poxviral vectors expressing both rabies and ox40 proteins, and vaccines made therefrom
WO2014063832A1 (en) * 2012-10-28 2014-05-01 Bavarian Nordig A/S Pr13.5 promoter for robust t-cell and antibody responses
US9993545B2 (en) * 2013-03-15 2018-06-12 The Trustees Of The University Of Pennsylvania Foot and mouth disease virus (FMDV) consensus proteins, coding sequences therefor and vaccines made therefrom
CN103740758B (zh) * 2013-12-18 2015-03-18 广东华南联合疫苗开发院有限公司 一种重组杆状病毒载体及病毒样颗粒及制备方法和用途
CN103710384A (zh) * 2013-12-18 2014-04-09 广东华南联合疫苗开发院有限公司 小核糖核酸病毒科重组载体和病毒样颗粒及制备方法和用途
MX2017003712A (es) 2014-09-23 2017-06-28 Merial Inc Vacunas recombinantes contra fmdv y sus usos.
CN104892734B (zh) * 2015-04-30 2019-09-13 中国科学院过程工程研究所 疏水作用层析提纯口蹄疫灭活病毒抗原的方法
WO2016202828A1 (en) * 2015-06-15 2016-12-22 Bavarian Nordic A/S Recombinant modified vaccinia virus ankara (mva) foot and mouth disease virus (fmdv) vaccine
KR102153303B1 (ko) 2015-11-23 2020-09-09 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 Fmdv 및 e2 융합 단백질 및 이의 용도
TWI760322B (zh) * 2016-01-29 2022-04-11 美商百靈佳殷格翰動物保健美國有限公司 重組腺病毒載體裝載之fmdv疫苗及其用途
MX2020008779A (es) 2018-02-23 2020-10-01 Boehringer Ingelheim Vetmedica Gmbh Sistemas de vectores virales recombinantes que expresan genes de paramixovirus felino exogenos y vacunas elaboradas a partir de estos.
GB202217045D0 (en) * 2022-11-15 2022-12-28 Univ Cape Town Recombinant lsdv vectored foot and mouth disease antigenic constructs
CN116656731B (zh) * 2023-05-25 2024-04-12 军事科学院军事医学研究院军事兽医研究所 一种表达非洲猪瘟病毒多种蛋白的重组金丝雀痘病毒及其构建方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3602530B2 (ja) * 1991-03-07 2004-12-15 ヴァイロジェネティクス コーポレイション 遺伝子操作したワクチン菌株
US5561064A (en) 1994-02-01 1996-10-01 Vical Incorporated Production of pharmaceutical-grade plasmid DNA
JPH10503086A (ja) 1994-07-15 1998-03-24 メルク エンド カンパニー インコーポレーテッド 大規模プラスミド精製方法
WO1996040880A1 (en) 1995-06-07 1996-12-19 Syntro Corporation Recombinant fowlpox viruses and uses thereof
BR0111366A (pt) * 2000-05-24 2003-05-20 Merial Sas Vacina de poxvìrus recombinante do vìrus da sìndrome respiratória e reprodutiva de porcino (prrsv)
FR2810888B1 (fr) * 2000-06-29 2004-07-30 Merial Sas Vaccin contre la fievre aphteuse
US7740863B2 (en) * 2001-04-06 2010-06-22 Merial Recombinant vaccine against West Nile Virus

Also Published As

Publication number Publication date
US20090253185A1 (en) 2009-10-08
ECSP077196A (es) 2007-02-28
CA2571560A1 (en) 2006-07-13
DK1773387T3 (da) 2013-07-15
CA2571560C (en) 2016-04-12
PL1773387T3 (pl) 2013-10-31
WO2006073431A3 (en) 2006-08-31
US20050287672A1 (en) 2005-12-29
EP1773387A4 (en) 2008-03-19
EP1773387A2 (en) 2007-04-18
WO2006073431A9 (en) 2006-10-05
WO2006073431A2 (en) 2006-07-13
BRPI0512421B1 (pt) 2014-09-09
EP1773387B1 (en) 2013-06-12
US7527960B2 (en) 2009-05-05
BRPI0512421A (pt) 2008-03-04
ES2424847T3 (es) 2013-10-09

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 20/04/2005, OBSERVADAS AS CONDICOES LEGAIS.

B25A Requested transfer of rights approved
B25A Requested transfer of rights approved