CN114634916B - 具有异源表位和/或改变的成熟切割位点的流感血凝素的组合物 - Google Patents
具有异源表位和/或改变的成熟切割位点的流感血凝素的组合物 Download PDFInfo
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- CN114634916B CN114634916B CN202210283751.3A CN202210283751A CN114634916B CN 114634916 B CN114634916 B CN 114634916B CN 202210283751 A CN202210283751 A CN 202210283751A CN 114634916 B CN114634916 B CN 114634916B
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K39/12—Viral antigens
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- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03H—IMPEDANCE NETWORKS, e.g. RESONANT CIRCUITS; RESONATORS
- H03H7/00—Multiple-port networks comprising only passive electrical elements as network components
- H03H7/01—Frequency selective two-port networks
- H03H7/0115—Frequency selective two-port networks comprising only inductors and capacitors
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- C—CHEMISTRY; METALLURGY
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K39/145—Orthomyxoviridae, e.g. influenza virus
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- C12N15/70—Vectors or expression systems specially adapted for E. coli
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- H—ELECTRICITY
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- H01L23/00—Details of semiconductor or other solid state devices
- H01L23/48—Arrangements for conducting electric current to or from the solid state body in operation, e.g. leads, terminal arrangements ; Selection of materials therefor
- H01L23/50—Arrangements for conducting electric current to or from the solid state body in operation, e.g. leads, terminal arrangements ; Selection of materials therefor for integrated circuit devices, e.g. power bus, number of leads
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- H—ELECTRICITY
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- H01L23/52—Arrangements for conducting electric current within the device in operation from one component to another, i.e. interconnections, e.g. wires, lead frames
- H01L23/522—Arrangements for conducting electric current within the device in operation from one component to another, i.e. interconnections, e.g. wires, lead frames including external interconnections consisting of a multilayer structure of conductive and insulating layers inseparably formed on the semiconductor body
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- H01L23/522—Arrangements for conducting electric current within the device in operation from one component to another, i.e. interconnections, e.g. wires, lead frames including external interconnections consisting of a multilayer structure of conductive and insulating layers inseparably formed on the semiconductor body
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- H01—ELECTRIC ELEMENTS
- H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
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- H—ELECTRICITY
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- H03F1/02—Modifications of amplifiers to raise the efficiency, e.g. gliding Class A stages, use of an auxiliary oscillation
- H03F1/0205—Modifications of amplifiers to raise the efficiency, e.g. gliding Class A stages, use of an auxiliary oscillation in transistor amplifiers
- H03F1/0211—Modifications of amplifiers to raise the efficiency, e.g. gliding Class A stages, use of an auxiliary oscillation in transistor amplifiers with control of the supply voltage or current
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- H03—ELECTRONIC CIRCUITRY
- H03F—AMPLIFIERS
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- H03F3/189—High-frequency amplifiers, e.g. radio frequency amplifiers
- H03F3/19—High-frequency amplifiers, e.g. radio frequency amplifiers with semiconductor devices only
- H03F3/195—High-frequency amplifiers, e.g. radio frequency amplifiers with semiconductor devices only in integrated circuits
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- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04B—TRANSMISSION
- H04B1/00—Details of transmission systems, not covered by a single one of groups H04B3/00 - H04B13/00; Details of transmission systems not characterised by the medium used for transmission
- H04B1/005—Details of transmission systems, not covered by a single one of groups H04B3/00 - H04B13/00; Details of transmission systems not characterised by the medium used for transmission adapting radio receivers, transmitters andtransceivers for operation on two or more bands, i.e. frequency ranges
- H04B1/0064—Details of transmission systems, not covered by a single one of groups H04B3/00 - H04B13/00; Details of transmission systems not characterised by the medium used for transmission adapting radio receivers, transmitters andtransceivers for operation on two or more bands, i.e. frequency ranges with separate antennas for the more than one band
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
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- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
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- C07K2319/50—Fusion polypeptide containing protease site
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- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- H—ELECTRICITY
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- Gastroenterology & Hepatology (AREA)
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- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- General Chemical & Material Sciences (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662290894P | 2016-02-03 | 2016-02-03 | |
| US62/290,894 | 2016-02-03 | ||
| PCT/US2017/016251 WO2017136575A1 (en) | 2016-02-03 | 2017-02-02 | Compositions of influenza hemagglutinin with heterologous epitopes and/or altered maturation cleavage sites |
| CN201780018856.3A CN109073639B (zh) | 2016-02-03 | 2017-02-02 | 具有异源表位和/或改变的成熟切割位点的流感血凝素的组合物 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201780018856.3A Division CN109073639B (zh) | 2016-02-03 | 2017-02-02 | 具有异源表位和/或改变的成熟切割位点的流感血凝素的组合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN114634916A CN114634916A (zh) | 2022-06-17 |
| CN114634916B true CN114634916B (zh) | 2024-12-20 |
Family
ID=63036971
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210283751.3A Active CN114634916B (zh) | 2016-02-03 | 2017-02-02 | 具有异源表位和/或改变的成熟切割位点的流感血凝素的组合物 |
| CN201780018856.3A Active CN109073639B (zh) | 2016-02-03 | 2017-02-02 | 具有异源表位和/或改变的成熟切割位点的流感血凝素的组合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201780018856.3A Active CN109073639B (zh) | 2016-02-03 | 2017-02-02 | 具有异源表位和/或改变的成熟切割位点的流感血凝素的组合物 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US10291197B2 (enExample) |
| EP (1) | EP3411712B1 (enExample) |
| JP (2) | JP7560938B2 (enExample) |
| KR (1) | KR102748840B1 (enExample) |
| CN (2) | CN114634916B (enExample) |
| AU (2) | AU2017215345B2 (enExample) |
| BR (1) | BR112018015765A2 (enExample) |
| CA (1) | CA3012703A1 (enExample) |
| MX (2) | MX380837B (enExample) |
| RU (2) | RU2769406C2 (enExample) |
| SG (2) | SG10202108573TA (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102465833B1 (ko) | 2017-11-28 | 2022-11-11 | 삼성전자주식회사 | 무선 통신 시스템에서 전력 설정 방법 및 이를 위한 장치 |
| KR102370100B1 (ko) * | 2019-02-15 | 2022-03-07 | 아이디바이오 주식회사 | 이종 인플루엔자 a 바이러스에 대한 면역/치료반응을 형성하는 신규한 재조합 인플루엔자 바이러스 및 이를 포함하는 유전자 전달체 및 치료백신 |
| CN117534737B (zh) * | 2022-07-15 | 2024-09-06 | 中山大学·深圳 | 一种季节性甲型流感通用Mosaic重组抗原及其疫苗和应用 |
| CN116874607B (zh) * | 2023-06-09 | 2024-12-10 | 山西高等创新研究院 | 一种h9亚型禽流感重组嵌合疫苗及其制备方法 |
| CN118978590B (zh) * | 2024-10-12 | 2025-01-21 | 北京溯本源和生物科技有限公司 | 一种利用重组流感病毒免疫小鼠制备杂交瘤单抗的方法及应用 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004034956A2 (de) * | 2002-10-16 | 2004-04-29 | TransMIT Gesellschaft für Technologietransfer mbH | 8-plasmid methode mit mutiertem ha gen zur herstellung eines influenza-impfstoffes |
| CN104185476A (zh) * | 2011-09-20 | 2014-12-03 | 西奈山医学院 | 流感病毒疫苗及其应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2084180A1 (en) * | 1991-12-11 | 1993-06-12 | Paul P. Hung | Expression of specific immunogens using viral antigens |
| EP0974660A1 (en) | 1998-06-19 | 2000-01-26 | Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) | Newcastle disease virus infectious clones, vaccines and diagnostic assays |
| DE10249294A1 (de) | 2002-10-22 | 2004-05-13 | Rohmax Additives Gmbh | Stabile Polymerdispersionen und Verfahren zur Herstellung |
| ES2539818T3 (es) * | 2007-08-02 | 2015-07-06 | Biondvax Pharmaceuticals Ltd. | Vacunas contra la gripe multiepitópicas multiméricas |
| AU2009270404B2 (en) * | 2008-07-18 | 2015-01-29 | Medicago Inc. | New influenza virus immunizing epitope |
| KR20110045008A (ko) | 2008-07-18 | 2011-05-03 | 아이디 바이오메디컬 코포레이션 오브 퀘벡 | 키메라 호흡기 세포융합 바이러스 폴리펩티드 항원 |
| CA2762042C (en) * | 2009-06-24 | 2012-11-20 | Medicago Inc. | Chimeric influenza virus-like particles comprising hemagglutinin |
| CN101857872A (zh) * | 2010-04-06 | 2010-10-13 | 浙江省医学科学院 | 甲型流感病毒抗原决定区更换方法 |
| WO2012114323A1 (en) * | 2011-02-22 | 2012-08-30 | Biondvax Pharmaceuticals Ltd. | Multimeric multiepitope polypeptides in improved seasonal and pandemic influenza vaccines |
| EP3027640B1 (en) * | 2013-08-03 | 2018-03-07 | Avatar Medical, LLC | Influenza hemagglutinin proteins and methods of use thereof |
| WO2016205347A1 (en) * | 2015-06-16 | 2016-12-22 | Icahn School Of Medicine At Mount Sinai | Influenza virus vaccines and uses thereof |
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Patent Citations (2)
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| WO2004034956A2 (de) * | 2002-10-16 | 2004-04-29 | TransMIT Gesellschaft für Technologietransfer mbH | 8-plasmid methode mit mutiertem ha gen zur herstellung eines influenza-impfstoffes |
| CN104185476A (zh) * | 2011-09-20 | 2014-12-03 | 西奈山医学院 | 流感病毒疫苗及其应用 |
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| EP3411712B1 (en) | 2025-11-19 |
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| US11979133B2 (en) | 2024-05-07 |
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| CN109073639B (zh) | 2022-04-01 |
| CN114634916A (zh) | 2022-06-17 |
| RU2769406C2 (ru) | 2022-03-31 |
| MX2021003392A (es) | 2021-05-27 |
| CN109073639A (zh) | 2018-12-21 |
| BR112018015765A2 (pt) | 2019-02-05 |
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| AU2024200382A1 (en) | 2024-03-07 |
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