JP2013533745A - ノロウイルスに由来する免疫原性組成物および方法 - Google Patents

ノロウイルスに由来する免疫原性組成物および方法 Download PDF

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JP2013533745A
JP2013533745A JP2013518791A JP2013518791A JP2013533745A JP 2013533745 A JP2013533745 A JP 2013533745A JP 2013518791 A JP2013518791 A JP 2013518791A JP 2013518791 A JP2013518791 A JP 2013518791A JP 2013533745 A JP2013533745 A JP 2013533745A
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norovirus
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JP2013533745A5 (enExample
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イーサン セッテンバー,
アンジェリカ メディナ−セルビー,
ドリス コイト,
フィリップ ドルミッツァー,
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ノバルティス アーゲー
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/295Polyvalent viral antigens; Mixtures of viral and bacterial antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08RNA viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/16011Caliciviridae
    • C12N2770/16022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/16011Caliciviridae
    • C12N2770/16023Virus like particles [VLP]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2013518791A 2010-07-06 2011-07-05 ノロウイルスに由来する免疫原性組成物および方法 Pending JP2013533745A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36158110P 2010-07-06 2010-07-06
US61/361,581 2010-07-06
PCT/US2011/042979 WO2012006293A1 (en) 2010-07-06 2011-07-05 Norovirus derived immunogenic compositions and methods

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JP2016000962A Division JP6351641B2 (ja) 2010-07-06 2016-01-06 ノロウイルスに由来する免疫原性組成物および方法

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JP2013533745A5 JP2013533745A5 (enExample) 2014-08-14

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JP2013518791A Pending JP2013533745A (ja) 2010-07-06 2011-07-05 ノロウイルスに由来する免疫原性組成物および方法
JP2016000962A Active JP6351641B2 (ja) 2010-07-06 2016-01-06 ノロウイルスに由来する免疫原性組成物および方法
JP2018030649A Withdrawn JP2018086020A (ja) 2010-07-06 2018-02-23 ノロウイルスに由来する免疫原性組成物および方法

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JP2018030649A Withdrawn JP2018086020A (ja) 2010-07-06 2018-02-23 ノロウイルスに由来する免疫原性組成物および方法

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US (3) US20130171185A1 (enExample)
EP (2) EP3153578A1 (enExample)
JP (3) JP2013533745A (enExample)
CN (1) CN103154242B (enExample)
AU (1) AU2011276328C1 (enExample)
CA (1) CA2804501C (enExample)
MX (1) MX2013000163A (enExample)
WO (1) WO2012006293A1 (enExample)

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JP2019149996A (ja) * 2018-03-06 2019-09-12 株式会社イーダブルニュートリション・ジャパン 貝類のノロウイルス不活化方法
JP2020515531A (ja) * 2017-03-28 2020-05-28 チルドレンズ ホスピタル メディカル センター ノロウイルスs粒子ベースのワクチンならびにその作製および使用方法
JP2021524273A (ja) * 2018-07-13 2021-09-13 メディカゴ インコーポレイテッド 改変ノロウイルスvp1タンパク質および改変ノロウイルスvp1タンパク質を含むvlp
WO2023176206A1 (ja) 2022-03-18 2023-09-21 デンカ株式会社 リンカーにより連結されたカプシドタンパク質を含むウイルス様粒子
US12539327B2 (en) 2023-10-19 2026-02-03 Children's Hospital Medical Center Norovirus S particle based vaccines and methods of making and using same

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FI4066857T3 (fi) 2010-08-31 2023-03-20 Glaxosmithkline Biologicals Sa Pegyloituja liposomeja immunogeeniä koodaavan rna:n kuljettamiseksi
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WO2017160124A2 (ko) * 2016-03-18 2017-09-21 연세대학교 산학협력단 노로 바이러스 백신을 생산하기 위한 재조합 발현 벡터
KR101914779B1 (ko) 2016-03-18 2018-11-02 (주)인테라 노로 바이러스 백신을 생산하기 위한 재조합 발현 벡터
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BR112022013537A2 (pt) * 2020-01-08 2022-11-22 Bharat Biotech Int Ltd Composições de vacina viral e métodos de preparações das mesmas
CN114316033A (zh) * 2020-09-29 2022-04-12 香港理工大学深圳研究院 一种特异性识别诺如病毒的单克隆抗体及制备方法与应用
CN115161343B (zh) * 2021-04-01 2024-06-04 苏州相奕生物技术有限公司 一种重组腺病毒表达载体及以其制备的多价诺如病毒疫苗
EP4422681A4 (en) * 2021-10-27 2025-11-19 Univ Pennsylvania VACCINE AGAINST A NOROVIRUS AND METHODS OF USE
WO2024144272A1 (ko) * 2022-12-27 2024-07-04 (주)한국바이오셀프 노로바이러스 gii mrna를 포함하는 백신 조성물
WO2024144262A1 (ko) * 2022-12-27 2024-07-04 (주)한국바이오셀프 노로바이러스 gi mrna를 포함하는 백신 조성물
CN118126202B (zh) * 2024-05-07 2024-07-30 上海瑞宙生物科技有限公司 一种诺如病毒类病毒颗粒及其应用

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JP2020515531A (ja) * 2017-03-28 2020-05-28 チルドレンズ ホスピタル メディカル センター ノロウイルスs粒子ベースのワクチンならびにその作製および使用方法
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JP7429684B2 (ja) 2018-07-13 2024-02-08 メディカゴ インコーポレイテッド 改変ノロウイルスvp1タンパク質および改変ノロウイルスvp1タンパク質を含むvlp
JP7429684B6 (ja) 2018-07-13 2024-03-15 メディカゴ インコーポレイテッド 改変ノロウイルスvp1タンパク質および改変ノロウイルスvp1タンパク質を含むvlp
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US10287324B2 (en) 2019-05-14
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US20160222066A1 (en) 2016-08-04
US20190023746A1 (en) 2019-01-24
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CN103154242A (zh) 2013-06-12
CA2804501A1 (en) 2012-01-12
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