JP2013532295A5 - - Google Patents
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- JP2013532295A5 JP2013532295A5 JP2013519748A JP2013519748A JP2013532295A5 JP 2013532295 A5 JP2013532295 A5 JP 2013532295A5 JP 2013519748 A JP2013519748 A JP 2013519748A JP 2013519748 A JP2013519748 A JP 2013519748A JP 2013532295 A5 JP2013532295 A5 JP 2013532295A5
- Authority
- JP
- Japan
- Prior art keywords
- individual
- biomarkers
- biomarker
- lung cancer
- assay
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000090 biomarker Substances 0.000 claims 40
- 238000000034 method Methods 0.000 claims 33
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 14
- 201000005202 lung cancer Diseases 0.000 claims 14
- 208000020816 lung neoplasm Diseases 0.000 claims 14
- 238000003556 assay Methods 0.000 claims 6
- 239000012472 biological sample Substances 0.000 claims 6
- 238000000099 in vitro assay Methods 0.000 claims 6
- 108091023037 Aptamer Proteins 0.000 claims 4
- 239000003153 chemical reaction reagent Substances 0.000 claims 4
- 230000002380 cytological effect Effects 0.000 claims 4
- 210000004072 lung Anatomy 0.000 claims 4
- 102100027998 Macrophage metalloelastase Human genes 0.000 claims 2
- 101710187853 Macrophage metalloelastase Proteins 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 108020004711 Nucleic Acid Probes Proteins 0.000 claims 2
- 238000004458 analytical method Methods 0.000 claims 2
- -1 antibodies Proteins 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 238000003745 diagnosis Methods 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 238000003018 immunoassay Methods 0.000 claims 2
- 108020004999 messenger RNA Proteins 0.000 claims 2
- 208000002154 non-small cell lung carcinoma Diseases 0.000 claims 2
- 239000002853 nucleic acid probe Substances 0.000 claims 2
- 238000004393 prognosis Methods 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 230000002685 pulmonary effect Effects 0.000 claims 2
- 210000002966 serum Anatomy 0.000 claims 2
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 claims 2
- 210000002381 plasma Anatomy 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36312210P | 2010-07-09 | 2010-07-09 | |
| US61/363,122 | 2010-07-09 | ||
| US201161444947P | 2011-02-21 | 2011-02-21 | |
| US61/444,947 | 2011-02-21 | ||
| PCT/US2011/043595 WO2012006632A2 (en) | 2010-07-09 | 2011-07-11 | Lung cancer biomarkers and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013532295A JP2013532295A (ja) | 2013-08-15 |
| JP2013532295A5 true JP2013532295A5 (enExample) | 2014-08-28 |
| JP5905003B2 JP5905003B2 (ja) | 2016-04-20 |
Family
ID=45441874
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013519748A Active JP5905003B2 (ja) | 2010-07-09 | 2011-07-11 | 肺癌バイオマーカーとその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US20130116150A1 (enExample) |
| EP (1) | EP2591357A4 (enExample) |
| JP (1) | JP5905003B2 (enExample) |
| KR (1) | KR101870123B1 (enExample) |
| CN (2) | CN104777313B (enExample) |
| AU (1) | AU2011274422B2 (enExample) |
| BR (1) | BR112012032537B8 (enExample) |
| CA (1) | CA2801110C (enExample) |
| IL (1) | IL223295A (enExample) |
| MX (2) | MX355020B (enExample) |
| SG (2) | SG10201508656VA (enExample) |
| WO (1) | WO2012006632A2 (enExample) |
Families Citing this family (93)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2021792B1 (en) | 2006-05-09 | 2013-02-27 | The University Of British Columbia | Dissolved protein arthritis markers |
| KR20180102215A (ko) | 2007-11-27 | 2018-09-14 | 더 유니버시티 오브 브리티쉬 콜롬비아 | 관절염의 진단과 치료를 위한 14-3-3 에타 항체 및 이의 용도 |
| US8285719B1 (en) | 2008-08-08 | 2012-10-09 | The Research Foundation Of State University Of New York | System and method for probabilistic relational clustering |
| US10359425B2 (en) * | 2008-09-09 | 2019-07-23 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| US20100221752A2 (en) * | 2008-10-06 | 2010-09-02 | Somalogic, Inc. | Ovarian Cancer Biomarkers and Uses Thereof |
| US9495515B1 (en) | 2009-12-09 | 2016-11-15 | Veracyte, Inc. | Algorithms for disease diagnostics |
| US10236078B2 (en) | 2008-11-17 | 2019-03-19 | Veracyte, Inc. | Methods for processing or analyzing a sample of thyroid tissue |
| WO2010102412A1 (en) | 2009-03-11 | 2010-09-16 | Augurex Life Sciences Corporation | Compositions and methods for characterizing arthritic conditions |
| EP3360978A3 (en) | 2009-05-07 | 2018-09-26 | Veracyte, Inc. | Methods for diagnosis of thyroid conditions |
| CA2801110C (en) | 2010-07-09 | 2021-10-05 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| CN106198980B (zh) | 2010-08-13 | 2018-09-07 | 私募蛋白质体公司 | 胰腺癌生物标记及其用途 |
| US20140235487A1 (en) * | 2010-11-12 | 2014-08-21 | William Marsh Rice University | Oral cancer risk scoring |
| PT2768851T (pt) | 2011-10-21 | 2017-09-08 | Augurex Life Sciences Corp | Antigénios derivados de 14-3-3 citrulinada e utilizações dos mesmos no diagnóstico de artrite reumatoide |
| US20130282390A1 (en) * | 2012-04-20 | 2013-10-24 | International Business Machines Corporation | Combining knowledge and data driven insights for identifying risk factors in healthcare |
| EP2841603A4 (en) * | 2012-04-26 | 2016-05-25 | Allegro Diagnostics Corp | METHODS OF ASSESSING THE STATUS OF LUNG CANCER |
| JP6022285B2 (ja) * | 2012-09-28 | 2016-11-09 | シスメックス株式会社 | 標本収納装置、標本収納方法、及び標本検査システム |
| AU2013340414B2 (en) | 2012-10-23 | 2019-05-02 | Caris Science, Inc. | Aptamers and uses thereof |
| US10942184B2 (en) | 2012-10-23 | 2021-03-09 | Caris Science, Inc. | Aptamers and uses thereof |
| CN104812913B (zh) | 2012-11-07 | 2019-03-15 | 私募蛋白质体公司 | 慢性阻塞性肺疾病(copd)生物标记及其用途 |
| EP2935628B1 (en) | 2012-12-19 | 2018-03-21 | Caris Life Sciences Switzerland Holdings GmbH | Compositions and methods for aptamer screening |
| EP2968988A4 (en) | 2013-03-14 | 2016-11-16 | Allegro Diagnostics Corp | METHOD FOR EVALUATING A COPD STATUS |
| US11976329B2 (en) | 2013-03-15 | 2024-05-07 | Veracyte, Inc. | Methods and systems for detecting usual interstitial pneumonia |
| US9612248B2 (en) | 2013-03-15 | 2017-04-04 | Somalogic, Inc. | Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) biomarkers and uses thereof |
| WO2014153327A1 (en) | 2013-03-18 | 2014-09-25 | Barbeau James M | Methods to determine carcinogenesis, identify markers for early cancer diagnosis and identify targets of therapy |
| WO2014187881A1 (en) * | 2013-05-21 | 2014-11-27 | Max-Planck Gesellschaft zur Förderung der Wissenschaften e.V. | Isoforms of gata6 and nkx2-1 as markers for diagnosis and therapy of cancer and as targets for anti-cancer therapy |
| KR101552014B1 (ko) | 2013-10-11 | 2015-09-09 | 인제대학교 산학협력단 | 폐암 진단을 위한 nir의 신규한 용도 |
| WO2015066564A1 (en) * | 2013-10-31 | 2015-05-07 | Cancer Prevention And Cure, Ltd. | Methods of identification and diagnosis of lung diseases using classification systems and kits thereof |
| BR112016010322A2 (pt) | 2013-11-07 | 2017-08-08 | Medial Res Ltd | Método computadorizado de avaliação de risco de câncer de pulmão, meio legível por computador, sistema de avaliação de câncer de pulmão, e método de geração de um classificador para avaliação de risco de câncer de pulmão |
| JP6703479B2 (ja) * | 2013-12-16 | 2020-06-03 | フィリップ モリス プロダクツ エス アー | 個人の喫煙ステータスを予測するためのシステムおよび方法 |
| RU2538625C1 (ru) * | 2014-01-20 | 2015-01-10 | Денис Николаевич Бахмутов | Способ диагностики рака |
| WO2015164617A1 (en) | 2014-04-24 | 2015-10-29 | Somalogic, Inc. | Tuberculosis biomarkers in urine and uses thereof |
| WO2015164616A1 (en) | 2014-04-24 | 2015-10-29 | Somalogic, Inc. | Biomarkers for detection of tuberculosis |
| WO2015164772A1 (en) * | 2014-04-25 | 2015-10-29 | Rush University Medical Center | Circulating insulin-like growth factor (igf)-associated proteins for the detection of lung cancer |
| US12297505B2 (en) | 2014-07-14 | 2025-05-13 | Veracyte, Inc. | Algorithms for disease diagnostics |
| CN114807368A (zh) * | 2014-07-14 | 2022-07-29 | 威拉赛特公司 | 用于评估肺癌状态的方法 |
| CA2961340C (en) | 2014-09-26 | 2023-10-17 | Somalogic, Inc. | Cardiovascular risk event prediction and uses thereof |
| US20170335396A1 (en) | 2014-11-05 | 2017-11-23 | Veracyte, Inc. | Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data |
| WO2016123058A1 (en) | 2015-01-27 | 2016-08-04 | Somalogic, Inc. | Biomarkers for detection of tuberculosis risk |
| WO2016182967A1 (en) | 2015-05-08 | 2016-11-17 | Somalogic, Inc. | Biomarkers for detection of tuberculosis risk |
| US20180259533A1 (en) * | 2015-09-09 | 2018-09-13 | Somalogic, Inc. | Methods for developing personalized drug treatment plans and targeted drug development based on proteomic profiles |
| JP6857185B2 (ja) * | 2015-09-11 | 2021-04-14 | アプタマー サイエンス インコーポレイテッドAptamer Sciences Inc. | 非小細胞肺癌診断用タンパク質バイオマーカーパネル及びこれを用いた非小細胞肺癌診断方法 |
| US10546650B2 (en) | 2015-10-23 | 2020-01-28 | Google Llc | Neural network for processing aptamer data |
| KR102687249B1 (ko) | 2016-02-08 | 2024-07-22 | 소마로직 오퍼레이팅 컴퍼니, 인코포레이티드 | 비알코올성 지방간 질환 (nafld)과 비알코올성 지방간염 (nash) 생물마커 및 이들의 용도 |
| JP6041331B1 (ja) * | 2016-02-26 | 2016-12-07 | 国立大学法人山口大学 | 情報処理装置と情報処理プログラム並びに情報処理方法 |
| JP6889428B2 (ja) * | 2016-02-26 | 2021-06-18 | 国立大学法人山口大学 | 情報処理装置と情報処理プログラム並びに情報処理方法 |
| CN107435062B (zh) * | 2016-05-25 | 2020-10-20 | 上海伯豪医学检验所有限公司 | 甄别肺部微小结节良恶性的外周血基因标志物及其用途 |
| AU2017277784B2 (en) | 2016-06-08 | 2022-06-30 | Research Development Foundation | Systems and methods for automated coronary plaque characterization and risk assessment using intravascular optical coherence tomography |
| CA3026809A1 (en) * | 2016-06-21 | 2017-12-28 | The Wistar Institute Of Anatomy And Biology | Compositions and methods for diagnosing lung cancers using gene expression profiles |
| EP3580560B1 (en) | 2017-02-09 | 2024-10-02 | Board Of Regents, The University Of Texas System | Methods for the detection and treatment of lung cancer |
| WO2018223066A1 (en) * | 2017-06-02 | 2018-12-06 | Veracyte, Inc. | Methods and systems for identifying or monitoring lung disease |
| CN109470855B (zh) * | 2017-09-08 | 2022-02-11 | 广州市丹蓝生物科技有限公司 | 肺癌早期诊断用蛋白芯片及试剂盒 |
| EP3728630A4 (en) | 2017-12-19 | 2021-11-17 | The Wistar Institute Of Anatomy And Biology | COMPOSITIONS AND METHODS OF DIAGNOSING LUNG CANCER USING GENE EXPRESSION PROFILES |
| KR102028967B1 (ko) | 2017-12-28 | 2019-10-07 | 한국원자력의학원 | Rip1을 포함하는 폐암 전이 진단용 바이오 마커 및 이의 이용 |
| US20210140977A1 (en) | 2018-04-16 | 2021-05-13 | University Of Cape Town | A three-protein proteomic biomarker for prospective determination of risk for development of active tuberculosis |
| JP7526102B2 (ja) * | 2018-06-22 | 2024-07-31 | ソマロジック・オペレイティング・カンパニー・インコーポレイテッド | 改良されたプロテオミクスマルチプレックスアッセイ |
| WO2020018005A1 (en) * | 2018-07-17 | 2020-01-23 | Limited Liability Company "Gero" | Devices, methods, compositions and systems for the treatment of aging and age- related disorders |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| KR102216645B1 (ko) * | 2018-10-29 | 2021-02-17 | 사회복지법인 삼성생명공익재단 | 폐암의 분자 아형 결정을 위한 바이오마커 패널 및 이의 용도 |
| AU2019371238B2 (en) * | 2018-10-30 | 2026-02-05 | Somalogic Operating Co., Inc. | Methods for sample quality assessment |
| CN109470859A (zh) * | 2018-11-04 | 2019-03-15 | 华东医院 | 一种外泌体蛋白作为鉴别肺结节良恶性标志物及其应用 |
| WO2020132520A2 (en) * | 2018-12-20 | 2020-06-25 | Veracyte, Inc. | Methods and systems for detecting genetic fusions to identify a lung disorder |
| EP3671210A1 (en) * | 2018-12-21 | 2020-06-24 | Biosystems International KFT | Lung cancer protein epitomic biomarkers |
| WO2020243574A1 (en) * | 2019-05-31 | 2020-12-03 | Delphinus Medical Technologies, Inc. | Systems and methods for interactive lesion characterization |
| US20210027890A1 (en) * | 2019-07-24 | 2021-01-28 | ConnSante BioTech, Inc. | Detecting, evaluating and predicting system for cancer risk |
| JP7712913B2 (ja) | 2019-09-03 | 2025-07-24 | ソマロジック オペレーティング カンパニー インコーポレイテッド | 心血管リスク/イベントの予測及びその使用 |
| CN115023615A (zh) | 2020-01-10 | 2022-09-06 | 私募蛋白质体操作有限公司 | 确定葡萄糖耐量减低的方法 |
| AU2021213150A1 (en) | 2020-01-30 | 2022-08-04 | Prognomiq Inc | Lung biomarkers and methods of use thereof |
| JP7766605B2 (ja) | 2020-02-10 | 2025-11-10 | ソマロジック オペレーティング カンパニー インコーポレイテッド | 非アルコール性脂肪性肝炎(nash)のバイオマーカー及びその使用 |
| KR102260915B1 (ko) | 2020-02-19 | 2021-06-04 | 한국원자력의학원 | 폐암의 방사선 치료 예후 예측을 위한 생체 표지자 |
| CN111876478B (zh) * | 2020-04-28 | 2025-11-21 | 中国科学院微生物研究所 | 肺结节诊断标志物及应用 |
| US20230304099A1 (en) * | 2020-08-14 | 2023-09-28 | The Medical College Of Wisconsin, Inc. | Gene Expression Signature for Predicting Immunotherapy Response and Methods of Use |
| JP2023545017A (ja) * | 2020-10-02 | 2023-10-26 | ボード オブ レジェンツ,ザ ユニバーシティ オブ テキサス システム | 肺がんの検出及び治療のための方法 |
| CN113960235B (zh) * | 2020-10-10 | 2023-03-14 | 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) | 生物标志物在制备肺癌检测试剂中的用途和方法 |
| CA3195924A1 (en) | 2020-10-20 | 2022-04-28 | Laura Mae SAMPSON | Cardiovascular event risk prediction |
| JP2024516522A (ja) * | 2021-03-31 | 2024-04-16 | プログノミック インコーポレイテッド | マルチオミクス評価 |
| GB2607436A (en) * | 2021-03-31 | 2022-12-07 | Prognomiq Inc | Multi-omic assessment |
| US20220328134A1 (en) | 2021-03-31 | 2022-10-13 | PrognomIQ, Inc. | Multi-omic assessment |
| US12387508B2 (en) | 2021-09-10 | 2025-08-12 | PrognomIQ, Inc. | Direct classification of raw biomolecule measurement data |
| EP4711762A1 (en) | 2021-09-13 | 2026-03-18 | Prognomiq Inc | Enhanced detection and quantitation of biomolecules |
| MX2024008874A (es) | 2022-01-21 | 2024-07-29 | Somalogic Operating Co Inc | Metodos de evaluacion de calidad de muestras. |
| CN118829883A (zh) | 2022-04-24 | 2024-10-22 | 私募蛋白质体操作有限公司 | 用于样品质量评估的方法 |
| AU2023259062A1 (en) | 2022-04-24 | 2024-09-12 | Somalogic Operating Co., Inc. | Methods for sample quality assessment |
| CN118765373A (zh) | 2022-04-24 | 2024-10-11 | 私募蛋白质体操作有限公司 | 用于样品质量评估的方法 |
| EP4515246A1 (en) | 2022-04-24 | 2025-03-05 | SomaLogic Operating Co., Inc. | Methods for sample quality assessment |
| WO2023244582A1 (en) * | 2022-06-13 | 2023-12-21 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Lung cancer-related biomarkers and methods of using the same |
| WO2024010854A1 (en) * | 2022-07-07 | 2024-01-11 | Diagnose Early, Inc. | Rapid generation of breath-based health reports and systems for use in the same |
| AU2023308198A1 (en) | 2022-07-14 | 2024-11-14 | Somalogic Operating Co., Inc. | Methods of assessing dementia risk |
| KR20250036127A (ko) | 2022-07-14 | 2025-03-13 | 소마로직 오퍼레이팅 컴퍼니, 인코포레이티드 | 샘플 품질 평가 방법 |
| EP4591066A2 (en) | 2022-09-23 | 2025-07-30 | SomaLogic Operating Co., Inc. | Methods of assessing tobacco use status |
| US20240200125A1 (en) * | 2022-12-16 | 2024-06-20 | Droplet Biosciences, Inc. | Analysis of effluent |
| CN116539894A (zh) * | 2023-05-08 | 2023-08-04 | 复旦大学附属中山医院 | Capg在制备病理性心肌肥厚检测试剂中的应用 |
| CN121336096A (zh) | 2023-07-06 | 2026-01-13 | 私募蛋白质体操作有限公司 | 干燥生物基质中的靶分子的检测 |
| CN120559238A (zh) * | 2025-05-27 | 2025-08-29 | 中国人民解放军总医院第一医学中心 | 蛋白质标志物在制备用于肺磨玻璃结节良恶性鉴别的产品中的应用 |
Family Cites Families (118)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5660985A (en) | 1990-06-11 | 1997-08-26 | Nexstar Pharmaceuticals, Inc. | High affinity nucleic acid ligands containing modified nucleotides |
| US20040254101A1 (en) | 1995-06-06 | 2004-12-16 | Human Genome Sciences, Inc. | Colon specific gene and protein and cancer |
| AU6688598A (en) | 1997-03-07 | 1998-09-22 | University Of Florida | Method for diagnosing and staging prostate cancer |
| AU3316600A (en) | 1999-02-22 | 2000-09-21 | Torben F. Orntoft | Gene expression in bladder tumors |
| EP1215500B1 (en) | 1999-09-10 | 2008-07-09 | Takashi Muramatsu | Early cancer tumor marker |
| EP1472352A4 (en) | 2000-03-06 | 2005-10-12 | Smithkline Beecham Corp | NEW COMPOUNDS |
| US20030224501A1 (en) | 2000-03-17 | 2003-12-04 | Young Paul E. | Bone morphogenic protein polynucleotides, polypeptides, and antibodies |
| US6596503B1 (en) * | 2000-08-18 | 2003-07-22 | East Carolina University | Monoclonal antibody DS6, tumor-associated antigen CA6, and methods of use thereof |
| US6631330B1 (en) | 2000-08-21 | 2003-10-07 | Assistance Publique-Hopitaux De Paris (Ap-Hp) | Diagnosis method of inflammatory, fibrotic or cancerous disease using biochemical markers |
| US6576423B2 (en) | 2000-12-08 | 2003-06-10 | The Board Of Regents Of The University Of Nebraska | Specific mucin expression as a marker for pancreatic cancer |
| JP2005527180A (ja) * | 2001-04-18 | 2005-09-15 | プロテイン デザイン ラブス, インコーポレイテッド | 肺がんの診断方法、肺がんの修飾因子の組成及びスクリーニングの方法 |
| US7189507B2 (en) | 2001-06-18 | 2007-03-13 | Pdl Biopharma, Inc. | Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer |
| US7622260B2 (en) | 2001-09-05 | 2009-11-24 | The Brigham And Women's Hospital, Inc. | Diagnostic and prognostic tests |
| US20040009489A1 (en) | 2001-09-28 | 2004-01-15 | Golub Todd R. | Classification of lung carcinomas using gene expression analysis |
| US20040241653A1 (en) * | 2001-12-31 | 2004-12-02 | Elena Feinstein | Methods for identifying marker genes for cancer |
| DK3115470T3 (en) | 2002-03-13 | 2018-11-05 | Genomic Health Inc | Gene Expression Profiling in Tumor Tissue Biopsies |
| US20050260639A1 (en) | 2002-09-30 | 2005-11-24 | Oncotherapy Science, Inc. | Method for diagnosing pancreatic cancer |
| JP4679149B2 (ja) | 2002-09-30 | 2011-04-27 | オンコセラピー・サイエンス株式会社 | ヒト膵癌に関連する遺伝子およびポリペプチド |
| WO2004046386A1 (en) | 2002-11-15 | 2004-06-03 | Genomic Health, Inc. | Gene expression profiling of egfr positive cancer |
| AU2003294828A1 (en) | 2002-12-17 | 2004-07-09 | Sinogenomax Co. Ltd. Chinese National Human Genomecenter | Specific markers for pancreatic cancer |
| WO2004061410A2 (en) | 2002-12-18 | 2004-07-22 | Ciphergen Biosystems, Inc. | Serum biomarkers in lung cancer |
| US20050181375A1 (en) | 2003-01-10 | 2005-08-18 | Natasha Aziz | Novel methods of diagnosis of metastatic cancer, compositions and methods of screening for modulators of metastatic cancer |
| US20040231909A1 (en) | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| AU2003900747A0 (en) | 2003-02-18 | 2003-03-06 | Garvan Institute Of Medical Research | Diagnosis and treatment of pancreatic cancer |
| US7767391B2 (en) | 2003-02-20 | 2010-08-03 | Genomic Health, Inc. | Use of intronic RNA to measure gene expression |
| CA2516591A1 (en) | 2003-02-26 | 2004-09-10 | Mount Sinai Hospital | Multiple marker assay for detection of ovarian cancer |
| WO2004099432A2 (en) | 2003-05-02 | 2004-11-18 | The Johns Hopkins University | Identification of biomarkers for detecting pancreatic cancer |
| CN1455257A (zh) * | 2003-05-23 | 2003-11-12 | 北京师范大学 | 一种利用表面修饰蛋白芯片进行肺癌诊断方法 |
| EP2003196A3 (en) | 2003-06-09 | 2009-01-07 | The Regents of the University of Michigan | Compositions and methods for treating and diagnosing cancer |
| DK1641810T4 (en) | 2003-06-24 | 2017-07-03 | Genomic Health Inc | Predicting the likelihood of cancer recurrence |
| ES2905579T3 (es) | 2003-07-10 | 2022-04-11 | Genomic Health Inc | Algoritmo del perfil de expresión y prueba para el pronóstico de la recaída del cáncer de mama |
| AU2004264948A1 (en) | 2003-08-15 | 2005-02-24 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Multifactorial assay for cancer detection |
| US7807392B1 (en) | 2003-09-15 | 2010-10-05 | Celera Corporation | Lung disease targets and uses thereof |
| US20070148648A1 (en) | 2003-11-04 | 2007-06-28 | Martin Dugas | Method for distinguishing who classified aml subtypes |
| EP1723428A2 (en) | 2004-02-19 | 2006-11-22 | Yale University Corporation | Identification of cancer protein biomarkers using proteomic techniques |
| WO2005086891A2 (en) | 2004-03-05 | 2005-09-22 | Rosetta Inpharmatics Llc | Classification of breast cancer patients using a combination of clinical criteria and informative genesets |
| EP1737980A2 (en) | 2004-04-09 | 2007-01-03 | Fondazione IRCCS Istituto Nazionale dei Tumori | Gene expression markers for predicting response to chemotherapy |
| JP4885122B2 (ja) | 2004-04-15 | 2012-02-29 | ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド | 癌、器官傷害、および筋肉リハビリテーション/運動過剰訓練についての診断の生物マーカーとしてのタンパク質分解マーカー |
| WO2005103281A2 (en) | 2004-04-26 | 2005-11-03 | Children's Medical Center Corporation | Platelet biomarkers for the detection of disease |
| US20070275422A1 (en) | 2004-07-26 | 2007-11-29 | The Board Of Trustees Of The Leland Stanford Jr. U | Methods and Compositions for Detecting Pancreatic Disease |
| KR20070043868A (ko) | 2004-08-02 | 2007-04-25 | 칠드런'즈 메디컬 센터 코포레이션 | 암에 대한 혈소판 바이오마커 |
| ATE483979T1 (de) | 2004-08-10 | 2010-10-15 | Oncotherapy Science Inc | Gen anln in verbindung mit nicht-kleinzelligem lungenkrebs und seine wechselwirkungen mit rhoa |
| JP2006053113A (ja) * | 2004-08-16 | 2006-02-23 | Medical Proteoscope Co Ltd | 肺腺癌リンパ節転移診断方法及び診断キット |
| WO2006052731A2 (en) | 2004-11-05 | 2006-05-18 | Genomic Health, Inc. | Molecular indicators of breast cancer prognosis and prediction of treatment response |
| CA2585571C (en) | 2004-11-05 | 2020-01-21 | Genomic Health, Inc. | Predicting response to chemotherapy using gene expression markers |
| US7862995B2 (en) | 2004-12-10 | 2011-01-04 | Targeted Molecular Diagnostics | Methods and materials for predicting responsiveness to treatment with dual tyrosine kinase inhibitor |
| US8632983B2 (en) | 2005-04-15 | 2014-01-21 | Van Andel Research Institute | Biomarkers for pancreatic cancer and diagnostic methods |
| US20070099209A1 (en) | 2005-06-13 | 2007-05-03 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| EP1904649A2 (en) | 2005-07-18 | 2008-04-02 | Epigenomics AG | Compositions and methods for cancer diagnostics comprising pan-cancer markers |
| US7521195B1 (en) | 2005-07-21 | 2009-04-21 | Celera Corporation | Lung disease targets and uses thereof |
| EP2295570A1 (en) | 2005-07-27 | 2011-03-16 | Oncotherapy Science, Inc. | Method of diagnosing small cell lung cancer |
| WO2007015947A2 (en) | 2005-07-29 | 2007-02-08 | Bayer Healthcare Llc | Methods and kits for the prediction of therapeutic success, recurrence free and overall survival in cancer therapies |
| US7582441B1 (en) | 2005-10-17 | 2009-09-01 | Celera Corporation | Methods and compositions for treating and diagnosing disease |
| EP1777523A1 (en) | 2005-10-19 | 2007-04-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | An in vitro method for the prognosis of progression of a cancer and of the outcome in a patient and means for performing said method |
| US8329408B2 (en) | 2005-10-31 | 2012-12-11 | Bayer Healthcare Llc | Methods for prognosis and monitoring cancer therapy |
| KR20080073740A (ko) * | 2005-11-10 | 2008-08-11 | 유니버시티 오브 캔터키 | 폐암 진단 검사 |
| US8445198B2 (en) | 2005-12-01 | 2013-05-21 | Medical Prognosis Institute | Methods, kits and devices for identifying biomarkers of treatment response and use thereof to predict treatment efficacy |
| US8014957B2 (en) | 2005-12-15 | 2011-09-06 | Fred Hutchinson Cancer Research Center | Genes associated with progression and response in chronic myeloid leukemia and uses thereof |
| EP3153860A3 (en) | 2005-12-22 | 2017-06-14 | Abbott Molecular Inc. | Methods and marker combinations for screening for predisposition to lung cancer |
| NZ593224A (en) | 2006-01-11 | 2012-10-26 | Genomic Health Inc | Gene expression markers (fap) for colorectal cancer prognosis |
| AU2007211085A1 (en) | 2006-01-27 | 2007-08-09 | Tripath Imaging, Inc. | Methods for identifying patients with an increased likelihood of having ovarian cancer and compositions therefor |
| CA2641315A1 (en) | 2006-02-06 | 2007-08-16 | Tethys Bioscience, Inc. | Osteoporosis associated markers and methods of use thereof |
| US7908091B2 (en) | 2006-03-17 | 2011-03-15 | Prometheus Laboratories Inc. | Methods of predicting and monitoring tyrosine kinase inhibitor therapy |
| US7888019B2 (en) | 2006-03-31 | 2011-02-15 | Genomic Health, Inc. | Genes involved estrogen metabolism |
| CA3086149A1 (en) | 2006-04-04 | 2007-10-11 | Singulex, Inc. | Highly sensitive system and methods for analysis of troponin |
| WO2007146229A2 (en) | 2006-06-07 | 2007-12-21 | Tethys Bioscience, Inc. | Markers associated with arteriovascular events and methods of use thereof |
| US20080090258A1 (en) | 2006-06-28 | 2008-04-17 | University Of Pittsburgh -Of The Commonwealth System Of Higher Education | Method and composition for diagnosing endometrial cancer |
| EP2090665A2 (en) | 2006-10-20 | 2009-08-19 | Exiqon A/S | Novel human microRNAs associated with cancer |
| EP2087140A2 (en) * | 2006-11-13 | 2009-08-12 | Source Precision Medicine, Inc. | Gene expression profiling for identification, monitoring, and treatment of lung cancer |
| US7964356B2 (en) | 2007-01-16 | 2011-06-21 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
| US7947447B2 (en) * | 2007-01-16 | 2011-05-24 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
| KR100846354B1 (ko) * | 2007-03-21 | 2008-07-15 | (주) 프로탄바이오 | 혈청 당단백질부터 분리한 폐암 진단용 마커 |
| ES2442919T3 (es) | 2007-03-27 | 2014-02-14 | Immunovia Ab | Firma/marcadores de proteínas para la detección de adenocarcinoma |
| RU2376372C2 (ru) | 2007-04-03 | 2009-12-20 | Государственное учреждение Научно-исследовательский институт медицинской генетики Томского научного центра Сибирского отделения Российской академии медицинских наук | Способ генетической диагностики подверженности к сердечно-сосудистым заболеваниям |
| EP2153232A1 (en) * | 2007-05-18 | 2010-02-17 | Duke University | Serum biomarkers for the early detection of lung cancer |
| WO2008153814A2 (en) | 2007-05-29 | 2008-12-18 | President And Fellows Of Harvard College | Molecules involved in regulation of osteoblast activity and osteoclast activity, and methods of use thereof |
| MX344253B (es) * | 2007-07-17 | 2016-12-09 | Somalogic Inc | Metodo para generar aptameros con constantes de disociacion mejoradas. |
| EP2019318A1 (en) | 2007-07-27 | 2009-01-28 | Erasmus University Medical Center Rotterdam | Protein markers for cardiovascular events |
| GB0717637D0 (en) | 2007-09-10 | 2007-10-17 | Univ Leiden | Future cardiac event biomarkers |
| WO2009036123A1 (en) * | 2007-09-11 | 2009-03-19 | Cancer Prevention And Cure, Ltd. | Method of identifying biomarkers in human serum indicative of pathologies of human lung tissues |
| US8541183B2 (en) * | 2007-09-11 | 2013-09-24 | Cancer Prevention And Cure, Ltd. | Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof |
| US20100267041A1 (en) | 2007-09-14 | 2010-10-21 | Predictive Biosciences, Inc. | Serial analysis of biomarkers for disease diagnosis |
| WO2009039023A2 (en) * | 2007-09-18 | 2009-03-26 | Board Of Regents Of The University Of Texas System | Detection of saliva proteins modulated secondary to ductal carcinoma in situ of the breast |
| JP5580205B2 (ja) | 2007-11-19 | 2014-08-27 | セレラ コーポレーション | 肺癌マーカーとその使用 |
| EP2238455A4 (en) | 2008-01-18 | 2011-03-02 | Vatrix Medical Inc | DIAGNOSTIC BIOMARKERS FOR VASCULAR ANEVISM |
| GB0803192D0 (en) | 2008-02-22 | 2008-04-02 | Mubio Products Bv | SCLC biomarker panel |
| US8067178B2 (en) | 2008-03-14 | 2011-11-29 | Genomic Health, Inc. | Gene expression markers for prediction of patient response to chemotherapy |
| US10359425B2 (en) * | 2008-09-09 | 2019-07-23 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| SI2340506T1 (sl) * | 2008-09-09 | 2016-02-29 | Somalogic, Inc. | Biomarkerji za pljučni rak in njihove uporabe |
| US20120143805A1 (en) | 2008-09-09 | 2012-06-07 | Somalogic, Inc. | Cancer Biomarkers and Uses Thereof |
| US20100221752A2 (en) | 2008-10-06 | 2010-09-02 | Somalogic, Inc. | Ovarian Cancer Biomarkers and Uses Thereof |
| US20120165217A1 (en) | 2008-10-06 | 2012-06-28 | Somalogic, Inc. | Cancer Biomarkers and Uses Thereof |
| CA2741117A1 (en) | 2008-10-30 | 2010-05-06 | Centre De Recherche Public De La Sante | Biomarkers for heart failure |
| US8541170B2 (en) | 2008-11-17 | 2013-09-24 | Veracyte, Inc. | Methods and compositions of molecular profiling for disease diagnostics |
| EP2366162A1 (en) | 2008-11-18 | 2011-09-21 | Collabrx, Inc. | Individualized cancer treatment |
| CN102308212A (zh) | 2008-12-04 | 2012-01-04 | 加利福尼亚大学董事会 | 用于确定前列腺癌诊断和预后的材料和方法 |
| AU2010259022B2 (en) | 2009-06-08 | 2016-05-12 | Singulex, Inc. | Highly sensitive biomarker panels |
| PT2264183T (pt) | 2009-06-09 | 2017-03-14 | Gendiag Exe Sl | Marcadores de risco para doença cardiovascular |
| EA201270020A1 (ru) | 2009-06-15 | 2012-07-30 | Кардиодкс, Инк. | Определение риска развития атеросклеротической болезни сердца |
| AU2010284199A1 (en) | 2009-08-19 | 2012-04-05 | The Cleveland Clinic Foundation | Marker detection for characterizing the risk of cardiovascular disease or complications thereof |
| WO2011035433A1 (en) * | 2009-09-23 | 2011-03-31 | University Health Network | Selected strains on serum-free growth media for proteomics analysis of lung cancer biomarkers |
| US9683996B2 (en) | 2009-10-22 | 2017-06-20 | The Regents Of The University Of California | Assessment of solid tumor burden |
| US9217747B2 (en) | 2009-10-29 | 2015-12-22 | Health Diagnostic Laboratory, Inc. | Protein and lipid biomarkers providing consistent improvement to the prediction of type 2 diabetes |
| US20120245235A1 (en) | 2009-12-01 | 2012-09-27 | Compenda Bioscience, Inc | Classification of cancers |
| CA2783536A1 (en) | 2009-12-09 | 2011-06-16 | Aviir, Inc. | Biomarker assay for diagnosis and classification of cardiovascular disease |
| WO2011094483A2 (en) | 2010-01-29 | 2011-08-04 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Immune gene signatures in cancer |
| WO2011100472A1 (en) | 2010-02-10 | 2011-08-18 | The Regents Of The University Of California | Salivary transcriptomic and proteomic biomarkers for breast cancer detection |
| KR20130056855A (ko) | 2010-03-01 | 2013-05-30 | 카리스 라이프 사이언스 룩셈부르크 홀딩스 | 치료진단용 생물학적 지표들 |
| KR20130043104A (ko) | 2010-04-06 | 2013-04-29 | 카리스 라이프 사이언스 룩셈부르크 홀딩스 | 질병용 순환 생물학적 지표들 |
| US20110256545A1 (en) * | 2010-04-14 | 2011-10-20 | Nancy Lan Guo | mRNA expression-based prognostic gene signature for non-small cell lung cancer |
| CA2801110C (en) | 2010-07-09 | 2021-10-05 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| CN106198980B (zh) | 2010-08-13 | 2018-09-07 | 私募蛋白质体公司 | 胰腺癌生物标记及其用途 |
| CA2809282C (en) | 2010-09-27 | 2017-09-12 | Somalogic, Inc. | Mesothelioma biomarkers and uses thereof |
| EP2702411A4 (en) * | 2011-04-29 | 2015-07-22 | Cancer Prevention & Cure Ltd | METHOD FOR IDENTIFICATION AND DIAGNOSIS OF LUNG DISEASES USING CLASSIFICATION SYSTEMS AND KITS THEREFOR |
| JP6652781B2 (ja) | 2011-09-30 | 2020-02-26 | ソマロジック・インコーポレーテッド | 心血管系リスクイベントの予測およびその使用 |
| JP5986638B2 (ja) | 2011-10-24 | 2016-09-06 | ソマロジック・インコーポレーテッド | 肺癌バイオマーカーおよびその使用 |
| CN104812913B (zh) | 2012-11-07 | 2019-03-15 | 私募蛋白质体公司 | 慢性阻塞性肺疾病(copd)生物标记及其用途 |
| SG10202006426QA (en) | 2013-11-21 | 2020-08-28 | Somalogic Inc | Cytidine-5-carboxamide modified nucleotide compositions and methods related thereto |
-
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