JP2014528576A5 - - Google Patents
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- JP2014528576A5 JP2014528576A5 JP2014533428A JP2014533428A JP2014528576A5 JP 2014528576 A5 JP2014528576 A5 JP 2014528576A5 JP 2014533428 A JP2014533428 A JP 2014533428A JP 2014533428 A JP2014533428 A JP 2014533428A JP 2014528576 A5 JP2014528576 A5 JP 2014528576A5
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- 239000000090 biomarker Substances 0.000 claims 27
- 238000000034 method Methods 0.000 claims 27
- 230000002526 effect on cardiovascular system Effects 0.000 claims 20
- 102100026802 72 kDa type IV collagenase Human genes 0.000 claims 5
- 101710151806 72 kDa type IV collagenase Proteins 0.000 claims 5
- 102100022524 Alpha-1-antichymotrypsin Human genes 0.000 claims 5
- 102100023701 C-C motif chemokine 18 Human genes 0.000 claims 5
- 108010028776 Complement C7 Proteins 0.000 claims 5
- 102100024336 Complement component C7 Human genes 0.000 claims 5
- 102100040898 Growth/differentiation factor 11 Human genes 0.000 claims 5
- 101710194452 Growth/differentiation factor 11 Proteins 0.000 claims 5
- 101000978371 Homo sapiens C-C motif chemokine 18 Proteins 0.000 claims 5
- 108010091628 alpha 1-Antichymotrypsin Proteins 0.000 claims 5
- 102000003801 alpha-2-Antiplasmin Human genes 0.000 claims 5
- 108090000183 alpha-2-Antiplasmin Proteins 0.000 claims 5
- 239000012472 biological sample Substances 0.000 claims 5
- 238000004458 analytical method Methods 0.000 claims 4
- 210000004369 blood Anatomy 0.000 claims 4
- 239000008280 blood Substances 0.000 claims 4
- 239000003153 chemical reaction reagent Substances 0.000 claims 4
- 238000004590 computer program Methods 0.000 claims 4
- 238000003384 imaging method Methods 0.000 claims 4
- 238000000338 in vitro Methods 0.000 claims 4
- 208000024172 Cardiovascular disease Diseases 0.000 claims 3
- 108091023037 Aptamer Proteins 0.000 claims 2
- 108020004711 Nucleic Acid Probes Proteins 0.000 claims 2
- 230000017531 blood circulation Effects 0.000 claims 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims 2
- 238000002592 echocardiography Methods 0.000 claims 2
- 230000002068 genetic effect Effects 0.000 claims 2
- 239000002853 nucleic acid probe Substances 0.000 claims 2
- 210000002381 plasma Anatomy 0.000 claims 2
- 238000012502 risk assessment Methods 0.000 claims 2
- 210000002966 serum Anatomy 0.000 claims 2
- 238000012360 testing method Methods 0.000 claims 2
- 210000002700 urine Anatomy 0.000 claims 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 1
- 208000031481 Pathologic Constriction Diseases 0.000 claims 1
- 238000002583 angiography Methods 0.000 claims 1
- 210000003423 ankle Anatomy 0.000 claims 1
- 230000036772 blood pressure Effects 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- 239000011575 calcium Substances 0.000 claims 1
- 235000012000 cholesterol Nutrition 0.000 claims 1
- 238000010968 computed tomography angiography Methods 0.000 claims 1
- 210000004351 coronary vessel Anatomy 0.000 claims 1
- 230000003247 decreasing effect Effects 0.000 claims 1
- 238000012217 deletion Methods 0.000 claims 1
- 230000037430 deletion Effects 0.000 claims 1
- 230000001419 dependent effect Effects 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 235000005911 diet Nutrition 0.000 claims 1
- 230000037213 diet Effects 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000014509 gene expression Effects 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 208000028867 ischemia Diseases 0.000 claims 1
- 238000009533 lab test Methods 0.000 claims 1
- 239000003550 marker Substances 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 230000035772 mutation Effects 0.000 claims 1
- 230000002107 myocardial effect Effects 0.000 claims 1
- 208000010125 myocardial infarction Diseases 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 102000054765 polymorphisms of proteins Human genes 0.000 claims 1
- 230000004044 response Effects 0.000 claims 1
- 230000000250 revascularization Effects 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 235000021003 saturated fats Nutrition 0.000 claims 1
- 230000000391 smoking effect Effects 0.000 claims 1
- 230000036262 stenosis Effects 0.000 claims 1
- 208000037804 stenosis Diseases 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 238000002604 ultrasonography Methods 0.000 claims 1
- 229940124549 vasodilator Drugs 0.000 claims 1
- 239000003071 vasodilator agent Substances 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019193933A JP6917432B2 (ja) | 2011-09-30 | 2019-10-25 | 心血管系リスクイベントの予測およびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161541828P | 2011-09-30 | 2011-09-30 | |
| US61/541,828 | 2011-09-30 | ||
| PCT/US2012/058060 WO2013049674A1 (en) | 2011-09-30 | 2012-09-28 | Cardiovascular risk event prediction and uses thereof |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018103211A Division JP6546318B2 (ja) | 2011-09-30 | 2018-05-30 | 心血管系リスクイベントの予測およびその使用 |
| JP2019193933A Division JP6917432B2 (ja) | 2011-09-30 | 2019-10-25 | 心血管系リスクイベントの予測およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014528576A JP2014528576A (ja) | 2014-10-27 |
| JP2014528576A5 true JP2014528576A5 (enExample) | 2015-11-12 |
| JP6652781B2 JP6652781B2 (ja) | 2020-02-26 |
Family
ID=47993164
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014533428A Active JP6652781B2 (ja) | 2011-09-30 | 2012-09-28 | 心血管系リスクイベントの予測およびその使用 |
| JP2018103211A Active JP6546318B2 (ja) | 2011-09-30 | 2018-05-30 | 心血管系リスクイベントの予測およびその使用 |
| JP2019193933A Active JP6917432B2 (ja) | 2011-09-30 | 2019-10-25 | 心血管系リスクイベントの予測およびその使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018103211A Active JP6546318B2 (ja) | 2011-09-30 | 2018-05-30 | 心血管系リスクイベントの予測およびその使用 |
| JP2019193933A Active JP6917432B2 (ja) | 2011-09-30 | 2019-10-25 | 心血管系リスクイベントの予測およびその使用 |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US20130085079A1 (enExample) |
| EP (1) | EP2761289B1 (enExample) |
| JP (3) | JP6652781B2 (enExample) |
| KR (2) | KR102248900B1 (enExample) |
| CN (4) | CN114518458A (enExample) |
| AU (1) | AU2013202112B9 (enExample) |
| BR (2) | BR112014007214B1 (enExample) |
| CA (2) | CA3074279C (enExample) |
| ES (1) | ES2777002T3 (enExample) |
| IL (1) | IL231387A (enExample) |
| IN (1) | IN2014CN01970A (enExample) |
| MX (2) | MX373248B (enExample) |
| RU (1) | RU2651708C2 (enExample) |
| SG (3) | SG10201607331WA (enExample) |
| WO (1) | WO2013049674A1 (enExample) |
| ZA (1) | ZA201401778B (enExample) |
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| US9434779B2 (en) * | 2012-03-19 | 2016-09-06 | The Brigham And Women's Hospital, Inc. | Growth differentiation factor 11 (GDF-11) for treatment of diastolic heart failure |
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