|
ITRM20030376A1
(it)
|
2003-07-31 |
2005-02-01 |
Univ Roma |
Procedimento per l'isolamento e l'espansione di cellule staminali cardiache da biopsia.
|
|
US11660317B2
(en)
|
2004-11-08 |
2023-05-30 |
The Johns Hopkins University |
Compositions comprising cardiosphere-derived cells for use in cell therapy
|
|
EP2475372B2
(en)
|
2009-09-10 |
2020-10-21 |
Velin-Pharma A/S |
Method for the preparation of micro-rna and its therapeutic application
|
|
EP2354246A1
(en)
|
2010-02-05 |
2011-08-10 |
febit holding GmbH |
miRNA in the diagnosis of ovarian cancer
|
|
US9845457B2
(en)
|
2010-04-30 |
2017-12-19 |
Cedars-Sinai Medical Center |
Maintenance of genomic stability in cultured stem cells
|
|
US9249392B2
(en)
|
2010-04-30 |
2016-02-02 |
Cedars-Sinai Medical Center |
Methods and compositions for maintaining genomic stability in cultured stem cells
|
|
US8716258B2
(en)
|
2010-06-04 |
2014-05-06 |
The Board Of Regents, The University Of Texas System |
Regulation of metabolism by miR-378
|
|
US10385314B2
(en)
*
|
2010-08-16 |
2019-08-20 |
Exostem Biotec Ltd. |
Methods of generating oligodendrocytes and cell populations comprising same
|
|
US8642751B2
(en)
|
2010-12-15 |
2014-02-04 |
Miragen Therapeutics |
MicroRNA inhibitors comprising locked nucleotides
|
|
US9771617B2
(en)
|
2011-06-27 |
2017-09-26 |
Eisai R&D Management Co., Ltd. |
Microrna biomarkers indicative of alzheimer's disease
|
|
CN102296112B
(zh)
*
|
2011-08-09 |
2013-06-05 |
南京医科大学 |
人类非梗阻性无精子症相关的精浆微小核糖核酸标志物及其应用
|
|
US20140274789A1
(en)
*
|
2011-08-11 |
2014-09-18 |
Andreas Keller |
Complex sets of mirnas as non-invasive biomarkers for psoriasis
|
|
US20140302068A1
(en)
*
|
2011-09-09 |
2014-10-09 |
The Regents Of The University Of Colorado |
MicroRNA Biomarkers for Diagnosing Parkinson's Disease
|
|
US9428749B2
(en)
|
2011-10-06 |
2016-08-30 |
The Board Of Regents, The University Of Texas System |
Control of whole body energy homeostasis by microRNA regulation
|
|
CN104080911A
(zh)
*
|
2011-11-30 |
2014-10-01 |
不来梅大学 |
miRNA在胎盘组织中的表达
|
|
ITRM20110685A1
(it)
|
2011-12-23 |
2013-06-24 |
Internat Ct For Genetic En Gineering And |
Microrna per la rigenerazione cardiaca attraverso l induzione della proliferazione dei miociti cardiaci
|
|
US11286463B2
(en)
|
2012-03-08 |
2022-03-29 |
Advanced ReGen Medical Technologies, LLC |
Reprogramming of aged adult stem cells
|
|
WO2013170146A1
(en)
|
2012-05-10 |
2013-11-14 |
Uab Research Foundation |
Methods and compositions for modulating mir-204 activity
|
|
EP2861238A4
(en)
|
2012-06-05 |
2016-03-16 |
Capricor Inc |
OPTIMIZED METHODS FOR GENERATING CARDIAC STEM CELLS FROM CARDIAC TISSUE AND THEIR USE IN CARDIAC THERAPY
|
|
JP6208228B2
(ja)
|
2012-06-21 |
2017-10-04 |
ミラゲン セラピューティクス， インコーポレイテッド |
ロックド核酸モチーフを含むオリゴヌクレオチドベースの阻害剤
|
|
CN102727909B
(zh)
*
|
2012-06-28 |
2014-06-04 |
中国人民解放军总医院 |
一种抑制原发性肝癌生长和转移的新方法
|
|
CN102787117A
(zh)
*
|
2012-07-20 |
2012-11-21 |
苏州大学 |
微小rna用于调控b7-h2基因表达
|
|
US9828603B2
(en)
|
2012-08-13 |
2017-11-28 |
Cedars Sinai Medical Center |
Exosomes and micro-ribonucleic acids for tissue regeneration
|
|
CN103667282A
(zh)
*
|
2012-08-30 |
2014-03-26 |
苏州博泰安生物科技有限公司 |
前列腺癌分子标志物miR-628-3P及其应用
|
|
EP2916853B1
(en)
*
|
2012-11-09 |
2020-05-06 |
Velin-Pharma A/S |
Compositions for pulmonary delivery
|
|
WO2014086243A1
(zh)
*
|
2012-12-07 |
2014-06-12 |
中国科学院上海生命科学研究院 |
负向调控I型干扰素通路的miRNA分子及其应用
|
|
CN103173448A
(zh)
*
|
2013-02-07 |
2013-06-26 |
上海市胸科医院 |
早期肺腺癌miRNA特异表达谱及其反转录引物和用途
|
|
US9675633B2
(en)
|
2013-03-14 |
2017-06-13 |
Board Of Regents, The University Of Texas System |
miRNA for treating cancer and for use with adoptive immunotherapies
|
|
US20160017326A1
(en)
*
|
2013-03-14 |
2016-01-21 |
The Trustees Of Princeton University |
Micrornas as functional mediators and biomarkers of bone metastasis
|
|
CN103157117B
(zh)
*
|
2013-03-19 |
2014-07-02 |
广州中国科学院先进技术研究所 |
一种调控肿瘤对trail耐受性的药物
|
|
JP6137894B2
(ja)
*
|
2013-03-22 |
2017-05-31 |
国立大学法人京都大学 |
リポソーム−エキソソームハイブリッドベシクル及びその調製法
|
|
CN103194542B
(zh)
*
|
2013-04-28 |
2014-03-26 |
夏彦恺 |
人类胎儿生长受限相关的血清微小核糖核酸标志物及其应用
|
|
CN103205430B
(zh)
*
|
2013-04-28 |
2015-04-15 |
夏彦恺 |
人类重度子痫前期发生相关的血清微小核糖核酸标志物及其应用
|
|
WO2014189850A1
(en)
|
2013-05-20 |
2014-11-27 |
The United States Of America, As Represented By The Secretary, Department Of Health & Human Services |
Detection and treatment of irritable bowel syndrome
|
|
US9879260B2
(en)
|
2013-08-20 |
2018-01-30 |
The Board Of Regents Of The University Of Texas System |
Micro-RNA regulation of bone loss
|
|
WO2015042435A1
(en)
*
|
2013-09-20 |
2015-03-26 |
Academia Sinica |
Treating diseases associated with pgc1-alpha by modulating micrornas mir-130a and mir-130b
|
|
US20160289763A1
(en)
*
|
2013-11-13 |
2016-10-06 |
The Texas A&M University System |
Micro-rnas that modulate lymphangiogenesis and inflammatory pathways in lymphatic vessel cells
|
|
WO2015081263A1
(en)
|
2013-11-26 |
2015-06-04 |
Central Biomedia, Inc. |
Method and diet for immune enhanced donor blood
|
|
CN103623431B
(zh)
*
|
2013-12-05 |
2015-04-22 |
南京大学 |
miR181s在制备治疗急性肠炎药物中的应用
|
|
RU2548816C1
(ru)
*
|
2013-12-16 |
2015-04-20 |
Мамонтова Марина Васильевна |
Способ выделения микрорнк из биологических жидкостей
|
|
WO2015091892A1
(en)
*
|
2013-12-19 |
2015-06-25 |
Comprehensive Biomarker Center Gmbh |
Mirnas as non-invasive biomarkers for parkinson's disease
|
|
US10772911B2
(en)
|
2013-12-20 |
2020-09-15 |
Advanced ReGen Medical Technologies, LLC |
Cell free compositions for cellular restoration and methods of making and using same
|
|
WO2015095794A1
(en)
|
2013-12-20 |
2015-06-25 |
Advanced ReGen Medical Technologies, LLC |
Compositions for cellular restoration and methods of making and using same
|
|
ES2760263T3
(es)
*
|
2014-03-21 |
2020-05-13 |
Genzyme Corp |
Tratamiento génico de la retinitis pigmentaria
|
|
KR101667650B1
(ko)
*
|
2014-03-31 |
2016-10-20 |
숙명여자대학교산학협력단 |
ｍｉＲ-192, ｍｉＲ-215 또는 ｍｉＲ-194를 포함하는 인간 상염색체 우성 다낭신 치료용 약학 조성물
|
|
CN103937826B
(zh)
*
|
2014-04-04 |
2016-04-06 |
东华大学 |
一种中枢神经系统中特异表达miR-505的载体的制备方法
|
|
WO2015189345A2
(en)
*
|
2014-06-13 |
2015-12-17 |
Universität Für Bodenkultur Wien |
Compositions and methods for the diagnosis and treatment of bone fractures and disorders
|
|
JP6566612B2
(ja)
*
|
2014-06-27 |
2019-08-28 |
国立大学法人北海道大学 |
免疫体質又は免疫応答型を判定するためのバイオマーカー及び免疫応答型制御剤
|
|
JP6385732B2
(ja)
*
|
2014-06-27 |
2018-09-05 |
国立大学法人北海道大学 |
免疫応答制御剤
|
|
CN105368822A
(zh)
*
|
2014-08-29 |
2016-03-02 |
香港大学 |
一种miRNA标记物、其方法和应用
|
|
CN105457039A
(zh)
*
|
2014-09-10 |
2016-04-06 |
洪挺祯 |
促进伤口愈合的制剂及其制备方法及使用方法
|
|
CN104306988B
(zh)
*
|
2014-09-25 |
2017-02-15 |
中国医学科学院基础医学研究所 |
miR‑431在制备治疗肌肉疾病的药物中的用途
|
|
US11357799B2
(en)
|
2014-10-03 |
2022-06-14 |
Cedars-Sinai Medical Center |
Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy
|
|
CN104491878A
(zh)
*
|
2014-12-19 |
2015-04-08 |
青岛大学 |
一种含有miRNA-324的药物组合物及其用途
|
|
EP3247716A4
(en)
|
2015-01-20 |
2018-10-17 |
Miragen Therapeutics, Inc. |
Mir-92 inhibitors and uses thereof
|
|
CN104830858A
(zh)
*
|
2015-03-05 |
2015-08-12 |
中国人民解放军第四军医大学 |
一种与浆液性卵巢癌发生发展机制相关的microRNA分子及其应用
|
|
CN105647919A
(zh)
*
|
2015-04-01 |
2016-06-08 |
四川大学华西医院 |
一种microRNA-129-5p的检测试剂盒和检测方法
|
|
CN104940954B
(zh)
*
|
2015-06-23 |
2017-12-26 |
同济大学 |
MicroRNA‑7在制备抗胶质化药物中的应用
|
|
US10441601B2
(en)
*
|
2015-06-30 |
2019-10-15 |
St. Jude Children's Research Hospital, Inc. |
Method for treating schizophrenia
|
|
WO2017004526A1
(en)
*
|
2015-07-02 |
2017-01-05 |
University Of Louisville Research Foundation, Inc. |
EDIBLE PLANT-DERIVED MICROVESICLE COMPOSITIONS FOR DELIVERY OF miRNA AND METHODS FOR TREATMENT OF CANCER
|
|
CN105497915A
(zh)
*
|
2015-07-21 |
2016-04-20 |
青岛大学附属医院 |
miR-223-3p或miR-885-5p模拟物在制备治疗急性痛风性关节炎药物中的应用
|
|
CN105363042B
(zh)
*
|
2015-10-21 |
2022-05-06 |
圣诺生物医药技术(苏州)有限公司 |
一种药物组合物及其应用
|
|
CN105288658B
(zh)
*
|
2015-10-30 |
2018-08-28 |
中国人民解放军第三军医大学 |
miR-18a-5p抑制剂在制备防治骨质疏松药物中的应用
|
|
WO2017078099A1
(ja)
|
2015-11-06 |
2017-05-11 |
東レ株式会社 |
癌の治療及び／又は予防用医薬組成物
|
|
WO2017099238A1
(ja)
|
2015-12-10 |
2017-06-15 |
東レ株式会社 |
癌の治療及び／又は予防用医薬組成物
|
|
EP3402543B1
(en)
|
2016-01-11 |
2021-09-08 |
Cedars-Sinai Medical Center |
Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction
|
|
JP6907939B2
(ja)
|
2016-01-28 |
2021-07-21 |
東レ株式会社 |
癌の治療及び／又は予防用医薬組成物
|
|
CN105854017A
(zh)
*
|
2016-03-01 |
2016-08-17 |
扬州大学 |
一种治疗β-地中海贫血的试剂及其应用
|
|
WO2017190000A1
(en)
*
|
2016-04-29 |
2017-11-02 |
Advanced ReGen Medical Technologies, LLC |
Microrna compositions and methods of making and using same
|
|
US11351200B2
(en)
|
2016-06-03 |
2022-06-07 |
Cedars-Sinai Medical Center |
CDC-derived exosomes for treatment of ventricular tachyarrythmias
|
|
EP3498284B1
(en)
|
2016-08-09 |
2021-07-14 |
Toray Industries, Inc. |
Pharmaceutical composition for treating and/or preventing cancer
|
|
IT201600093825A1
(it)
|
2016-09-19 |
2018-03-19 |
Fondazione St Italiano Tecnologia |
Composizione farmaceutica di miRNA e suoi usi terapeutici.
|
|
EP3515459A4
(en)
|
2016-09-20 |
2020-08-05 |
Cedars-Sinai Medical Center |
CELLS DERIVED FROM CARDIOSPHERES AND THEIR EXTRACELLULAR VESICLES TO DELAY OR REVERSE AGING AND AGE-RELATED DISORDERS
|
|
WO2018139759A1
(ko)
*
|
2017-01-26 |
2018-08-02 |
주식회사 바이오오케스트라 |
마이크로 rna를 이용한 알츠하이머병 진단방법
|
|
US11759482B2
(en)
|
2017-04-19 |
2023-09-19 |
Cedars-Sinai Medical Center |
Methods and compositions for treating skeletal muscular dystrophy
|
|
WO2018208969A1
(en)
*
|
2017-05-09 |
2018-11-15 |
New York University |
Micrornas for treatment of neuropathic pain
|
|
CN108853131A
(zh)
*
|
2017-05-11 |
2018-11-23 |
北京捷腾生物科技有限公司 |
携带miR-185的外泌体及其用途
|
|
CN107412250B
(zh)
*
|
2017-05-11 |
2019-03-05 |
南京北恒生物科技有限公司 |
miR-193a-3p的应用
|
|
CN107287319B
(zh)
*
|
2017-07-13 |
2021-07-02 |
青岛大学 |
miRNA-485-5p核苷酸类似物及其反义核苷酸的应用和应用其的产品
|
|
KR101956315B1
(ko)
*
|
2017-07-19 |
2019-03-08 |
국민대학교 산학협력단 |
파킨슨병 바이오마커로서의 miR494 및 이를 이용한 진단키트
|
|
CN107419022B
(zh)
*
|
2017-08-17 |
2021-03-16 |
武汉大学 |
与绝经后骨质疏松相关的miRNA标志物和试剂盒
|
|
CN107693535A
(zh)
*
|
2017-09-05 |
2018-02-16 |
上海市光华中西医结合医院 |
一种microRNA的应用
|
|
CN109722473A
(zh)
*
|
2017-10-31 |
2019-05-07 |
中国科学院深圳先进技术研究院 |
与骨代谢疾病相关的miRNA标志物miR-19b的应用
|
|
WO2019103300A1
(ko)
*
|
2017-11-27 |
2019-05-31 |
(주)프로스테믹스 |
Mirna를 포함하는 상처 치료 또는 피부 개선용 조성물
|
|
US11660355B2
(en)
|
2017-12-20 |
2023-05-30 |
Cedars-Sinai Medical Center |
Engineered extracellular vesicles for enhanced tissue delivery
|
|
EP3740576A4
(en)
|
2018-01-18 |
2021-10-20 |
Advanced Regen Medical Technologies, LLC |
THERAPEUTIC COMPOSITIONS AND THEIR PREPARATION AND USE METHODS
|
|
EP3749344A4
(en)
|
2018-02-05 |
2022-01-26 |
Cedars-Sinai Medical Center |
METHODS OF THERAPEUTIC USE OF EXOSOMES AND Y-RNAS
|
|
CN108853132A
(zh)
*
|
2018-05-22 |
2018-11-23 |
深圳先进技术研究院 |
一种miR-340调控IL-17A表达的用途
|
|
EP3820483A4
(en)
*
|
2018-07-13 |
2023-03-01 |
Yale University |
COMPOSITIONS AND METHODS FOR THE TREATMENT OF ENDOMETRIOSIS
|
|
WO2020030750A1
(en)
|
2018-08-08 |
2020-02-13 |
Theramir Ltd |
Microrna-based therapy targeted against lcp-1 positive cancers
|
|
CN110038026B
(zh)
*
|
2019-03-27 |
2021-08-17 |
浙江大学 |
mmu-miR-218-5p在制备抑制胚胎着床的药物中的应用
|
|
CN110075122B
(zh)
*
|
2019-05-09 |
2021-04-20 |
复旦大学附属中山医院 |
一种肝癌治疗性外泌体药物
|
|
US11198908B2
(en)
|
2019-06-17 |
2021-12-14 |
Biorchestra Co., Ltd. |
Method for diagnosis of Alzheimer's disease using microRNA
|
|
MX2022000074A
(es)
*
|
2019-07-02 |
2022-04-06 |
Ohio State Innovation Foundation |
Terapias para enfermedades neurodegenerativas que usan el eje piel cerebro.
|
|
KR102323535B1
(ko)
*
|
2019-07-10 |
2021-11-08 |
주식회사 엠디헬스케어 |
당뇨병성 신증 진단용 조성물
|
|
IT201900017234A1
(it)
*
|
2019-09-25 |
2021-03-25 |
Int Centre For Genetic Engineering And Biotechnology |
Anti-miRNA per il trattamento del leiomioma
|
|
CN110791560B
(zh)
*
|
2019-11-06 |
2021-09-14 |
中国医学科学院医药生物技术研究所 |
一种用于阿尔茨海默病诊断和/或治疗的miRNA标志物
|
|
TW202134437A
(zh)
*
|
2019-11-29 |
2021-09-16 |
比利時商諾瓦迪生物科學公司 |
用於預防及治療組織疾病之基於ｍｉＲＮＡ之醫藥組成物及其用途
|
|
CN111330008B
(zh)
*
|
2020-02-11 |
2021-02-05 |
四川大学 |
miR-93抑制剂在制备修复牙本质的药物中的用途
|
|
CN111529713B
(zh)
*
|
2020-05-11 |
2021-10-22 |
山东大学 |
一种AuNPs/miR-140复合物及其制备方法和应用
|
|
CN111840310B
(zh)
*
|
2020-07-27 |
2021-11-26 |
中国农业科学院兰州兽医研究所 |
ssc-miR-151-3p在制备调节猪繁殖与呼吸综合征病毒复制的药物中的应用
|
|
KR102371833B1
(ko)
*
|
2020-09-14 |
2022-03-08 |
서울대학교산학협력단 |
GDF11 유전자의 발현을 조절하는 microRNA 및 이를 함유하는 조성물
|
|
CN112410414B
(zh)
*
|
2020-10-09 |
2022-07-08 |
嘉兴市妇幼保健院 |
孕妇血清外泌体miRNA标志物在制备胎儿先心病早期诊断产品中的应用及试剂盒
|
|
CN112359040B
(zh)
*
|
2020-11-02 |
2021-09-14 |
广东省科学院动物研究所 |
调节let-7基因表达量的制剂在制备调节蜜蜂糖反应性行为制剂中的应用
|
|
CN112402440A
(zh)
*
|
2020-11-18 |
2021-02-26 |
西安组织工程与再生医学研究所 |
miR-325核酸类似物在制备治疗血窦内皮细胞病理性功能异常相关产品中的应用
|
|
CN112458165A
(zh)
*
|
2020-12-27 |
2021-03-09 |
中山大学孙逸仙纪念医院 |
一种阿尔茨海默病的预测标志物、检测试剂盒及应用
|
|
CN114438187B
(zh)
*
|
2021-01-29 |
2022-08-26 |
浙江大学医学院附属妇产科医院 |
一种诊断早期流产的miRNA标志物及其应用
|
|
CN114214328A
(zh)
*
|
2021-12-17 |
2022-03-22 |
川北医学院附属医院 |
一种核酸药物及其应用
|
|
WO2024047115A1
(en)
|
2022-09-02 |
2024-03-07 |
Leibniz-Institut Für Immuntherapie (Lit) |
THERAPEUTIC USE OF THE miR155 SNP rs377265631
|
|
WO2025054607A1
(en)
*
|
2023-09-07 |
2025-03-13 |
The Regents Of The University Of California |
Compositions and methods for treating sarcopenia
|
|
CN117257822B
(zh)
*
|
2023-09-23 |
2025-10-28 |
广州四叶草健康科技有限公司 |
一种治疗阿尔兹海默病的外泌体混合液及其制备方法
|
|
CN117683883B
(zh)
*
|
2024-01-11 |
2024-12-20 |
山东中医药大学 |
miR-126-5p在不明原因复发性自然流产诊治中的应用
|
|
CN118105400B
(zh)
*
|
2024-03-14 |
2024-08-20 |
南京市妇幼保健院 |
一种人子宫内膜间充质干细胞外泌体来源的微小RNA miR-30b及其应用
|
|
CN119040464B
(zh)
*
|
2024-10-16 |
2025-04-18 |
合肥工业大学 |
一种口腔鳞状细胞癌诊断生物标志物hsa-miR-331-3p及其应用
|