JP2013500322A5 - - Google Patents
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- Publication number
- JP2013500322A5 JP2013500322A5 JP2012522244A JP2012522244A JP2013500322A5 JP 2013500322 A5 JP2013500322 A5 JP 2013500322A5 JP 2012522244 A JP2012522244 A JP 2012522244A JP 2012522244 A JP2012522244 A JP 2012522244A JP 2013500322 A5 JP2013500322 A5 JP 2013500322A5
- Authority
- JP
- Japan
- Prior art keywords
- solution
- solution according
- preservative
- amount
- optional
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000000243 solution Substances 0.000 claims 30
- 239000003755 preservative agent Substances 0.000 claims 10
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims 8
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims 8
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 8
- 230000002335 preservative effect Effects 0.000 claims 8
- 239000002202 Polyethylene glycol Substances 0.000 claims 7
- 229920001223 polyethylene glycol Polymers 0.000 claims 7
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims 6
- 235000003599 food sweetener Nutrition 0.000 claims 5
- 239000003765 sweetening agent Substances 0.000 claims 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 5
- 235000011164 potassium chloride Nutrition 0.000 claims 4
- 239000001103 potassium chloride Substances 0.000 claims 4
- 235000017557 sodium bicarbonate Nutrition 0.000 claims 4
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims 4
- 239000011780 sodium chloride Substances 0.000 claims 4
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 claims 3
- 206010010774 Constipation Diseases 0.000 claims 3
- 229960001617 ethyl hydroxybenzoate Drugs 0.000 claims 3
- 235000010228 ethyl p-hydroxybenzoate Nutrition 0.000 claims 3
- 239000004403 ethyl p-hydroxybenzoate Substances 0.000 claims 3
- NUVBSKCKDOMJSU-UHFFFAOYSA-N ethylparaben Chemical compound CCOC(=O)C1=CC=C(O)C=C1 NUVBSKCKDOMJSU-UHFFFAOYSA-N 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 claims 3
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 claims 3
- 229960002216 methylparaben Drugs 0.000 claims 3
- 239000004376 Sucralose Substances 0.000 claims 2
- 239000007864 aqueous solution Substances 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 235000015205 orange juice Nutrition 0.000 claims 2
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 claims 2
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 claims 2
- 235000019408 sucralose Nutrition 0.000 claims 2
- WBZFUFAFFUEMEI-UHFFFAOYSA-M Acesulfame k Chemical compound [K+].CC1=CC(=O)[N-]S(=O)(=O)O1 WBZFUFAFFUEMEI-UHFFFAOYSA-M 0.000 claims 1
- 229920002562 Polyethylene Glycol 3350 Polymers 0.000 claims 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims 1
- YGCFIWIQZPHFLU-UHFFFAOYSA-N acesulfame Chemical compound CC1=CC(=O)NS(=O)(=O)O1 YGCFIWIQZPHFLU-UHFFFAOYSA-N 0.000 claims 1
- 229960005164 acesulfame Drugs 0.000 claims 1
- 239000000619 acesulfame-K Substances 0.000 claims 1
- 230000002421 anti-septic effect Effects 0.000 claims 1
- 235000019445 benzyl alcohol Nutrition 0.000 claims 1
- 229960004217 benzyl alcohol Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 235000013399 edible fruits Nutrition 0.000 claims 1
- 239000000796 flavoring agent Substances 0.000 claims 1
- 235000019634 flavors Nutrition 0.000 claims 1
- 239000008369 fruit flavor Substances 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0913295.2 | 2009-07-30 | ||
| GBGB0913295.2A GB0913295D0 (en) | 2009-07-30 | 2009-07-30 | Improvements in and relating to pharmaceutical compositions |
| PCT/GB2010/001455 WO2011012866A1 (en) | 2009-07-30 | 2010-07-30 | Solutions comprising polyethylene glycol and electrolytes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013500322A JP2013500322A (ja) | 2013-01-07 |
| JP2013500322A5 true JP2013500322A5 (enExample) | 2013-09-12 |
| JP5708943B2 JP5708943B2 (ja) | 2015-04-30 |
Family
ID=41067102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012522244A Active JP5708943B2 (ja) | 2009-07-30 | 2010-07-30 | ポリエチレングリコール及び電解質を含む溶液 |
Country Status (32)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201200637D0 (en) | 2012-01-13 | 2012-02-29 | Norgine Bv | Improvements in and relating to compositions |
| KR101852502B1 (ko) | 2011-01-31 | 2018-04-26 | 노어긴 비.브이. | 조성물에 관한 개선 |
| TWI535461B (zh) | 2011-03-11 | 2016-06-01 | 諾金私人有限公司 | 結腸清潔溶液、用於製備該溶液之組成物、包含該組成物或溶液之套組、與製備該溶液之方法 |
| CN102600201B (zh) * | 2012-02-07 | 2014-07-16 | 舒泰神（北京）生物制药股份有限公司 | 用于通便和清肠的药物组合物及其制备方法 |
| US20140065076A1 (en) * | 2012-08-30 | 2014-03-06 | Otsuka Pharmaceutical Co. Ltd. | Container with concentrated substance and method of using the same |
| NZ743984A (en) | 2012-09-11 | 2019-10-25 | Norgine Bv | Compositions comprising polyethylene glycol, alkali metal or alkaline earth metal sulphates and electrolytes for use as colon cleansing compositions |
| JP6441890B2 (ja) | 2013-03-15 | 2018-12-19 | ブレインツリー・ラボラトリーズ，インコーポレイテッド | 硫酸塩の両用経口薬学的組成物錠剤およびその使用の方法 |
| CN112494511A (zh) * | 2020-12-06 | 2021-03-16 | 天津康哲医药科技发展有限公司 | 一种聚乙二醇钠钾口服药物制剂的制备 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0231356A1 (en) * | 1985-08-01 | 1987-08-12 | Braintree Laboratories, Inc. | Low-sodium laxative and lavage formulation |
| JP2596764B2 (ja) | 1987-11-18 | 1997-04-02 | ルセル森下株式会社 | 腸管洗浄液剤 |
| US5378470A (en) | 1989-07-25 | 1995-01-03 | Henning Berlin Gmbh | Rectally administered pharmaceutical preparation |
| EP0670725A1 (en) | 1992-11-24 | 1995-09-13 | Block Drug Company, Inc. | Pharmaceutical compositions for use in gastrointestinal washes |
| RU2111741C1 (ru) * | 1994-10-27 | 1998-05-27 | Государственный научный центр колопроктологии Министерства здравоохранения и медицинской промышленности Российской Федерации | Вещество для общего промывания желудочно-кишечного тракта |
| US5710183A (en) | 1995-07-14 | 1998-01-20 | Halow; George M. | Laxative/antidiarrheal composition comprising polyethylene glycol and fiber bulking agent |
| US6162464A (en) | 1997-03-31 | 2000-12-19 | Inkine Pharmaceutical, Inc. | Non-aqueous colonic purgative formulations |
| US6071523A (en) | 1998-06-03 | 2000-06-06 | Taro Pharmaceuticals Industries, Ltd. | Spill resistant pharmaceutical compositions in semi-solid form |
| US6048901A (en) | 1999-04-20 | 2000-04-11 | Braintree Laboratories, Inc. | Method of reducing intestinal gas, cramping and anorectal irritation |
| IL137275A0 (en) | 2000-07-12 | 2001-07-24 | Yosefus Azaria | Pharmaceutical composition for the treatment of anal fissures |
| ATE477790T1 (de) | 2001-10-29 | 2010-09-15 | Ajinomoto Kk | Lösung zur darmreinigung |
| US6946149B2 (en) | 2002-04-30 | 2005-09-20 | Braintree Laboratories, Inc. | Salt solution for colon cleansing |
| US7291324B2 (en) * | 2002-10-22 | 2007-11-06 | Braintree Laboratories Inc. | Method of bowel cleansing |
| GB0224909D0 (en) * | 2002-10-25 | 2002-12-04 | Norgine Europe Bv | Colon cleansing compositions |
| US7332184B2 (en) | 2003-03-28 | 2008-02-19 | Queen's University At Kingston | Colonic cleansing composition and method |
| PL1663257T3 (pl) | 2003-07-09 | 2009-08-31 | Braintree Laboratories Inc | Zastosowanie środków przeczyszczających do leczenia zespołu jelita drażliwego |
| WO2005049049A1 (en) * | 2003-11-17 | 2005-06-02 | Braintree Laboratories, Inc. | Therapeutic peg solution concentrate |
| GB0409104D0 (en) | 2004-04-23 | 2004-05-26 | Norgine Europe Bv | Compressed pharmaceutical compositions |
| WO2006122104A1 (en) * | 2005-05-06 | 2006-11-16 | Salix Pharmaceuticals, Inc. | Polyethylene glycol colonic purgative composition |
| US20070082061A1 (en) * | 2005-10-07 | 2007-04-12 | Nelson Ayala | Reduction of saltiness with sweeteners |
| DE102006001199A1 (de) | 2006-01-10 | 2007-07-12 | Medicoforum Gmbh | Fixe Kombination von Substanzen unter Beigabe von Entschäumern zum Einsatz als Darmspüllösung und/oder Laxans |
| ES2278537B1 (es) | 2006-01-30 | 2008-09-16 | Laboratorios Casen-Fleet, S.L. | Procedimiento de fabricacion de una solucion a base de polietilenglicol con electrolitos, producto obtenido y uso. |
| CN1850112B (zh) * | 2006-03-06 | 2011-06-29 | 北京圣永制药有限公司 | 聚乙二醇-电解质口服溶液 |
| DE112008002398A5 (de) * | 2007-09-22 | 2010-07-29 | Bayer Consumer Care Ag | Zusammensetzung mit Wirkstoffkombination aus einem Laxans und einem Entschäumer zur Behandlung von Obstipation |
| US8362083B2 (en) * | 2008-01-15 | 2013-01-29 | C.B. Fleet Company Inc. | Taste-masked docusate compositions |
-
2009
- 2009-07-30 GB GBGB0913295.2A patent/GB0913295D0/en not_active Ceased
-
2010
- 2010-07-30 MX MX2012001108A patent/MX337114B/es active IP Right Grant
- 2010-07-30 PT PT10739973T patent/PT2459218T/pt unknown
- 2010-07-30 AU AU2010277354A patent/AU2010277354B2/en active Active
- 2010-07-30 ES ES201090080A patent/ES2388095B1/es active Active
- 2010-07-30 FR FR1056333A patent/FR2948569B3/fr not_active Expired - Lifetime
- 2010-07-30 CN CN201410088148.5A patent/CN103932979B/zh active Active
- 2010-07-30 BE BE2010/0471A patent/BE1019753A5/fr active
- 2010-07-30 GB GB1108383.9A patent/GB2478076B/en active Active
- 2010-07-30 EA EA201200220A patent/EA025112B1/ru unknown
- 2010-07-30 LT LTEP10739973.5T patent/LT2459218T/lt unknown
- 2010-07-30 SI SI201031928T patent/SI2459218T1/sl unknown
- 2010-07-30 SM SM20190569T patent/SMT201900569T1/it unknown
- 2010-07-30 HR HRP20191465 patent/HRP20191465T1/hr unknown
- 2010-07-30 CA CA2769247A patent/CA2769247C/en active Active
- 2010-07-30 WO PCT/GB2010/001455 patent/WO2011012866A1/en not_active Ceased
- 2010-07-30 EP EP10739973.5A patent/EP2459218B1/en active Active
- 2010-07-30 NZ NZ597822A patent/NZ597822A/xx unknown
- 2010-07-30 DK DK10739973.5T patent/DK2459218T3/da active
- 2010-07-30 KR KR1020127005284A patent/KR101868834B1/ko active Active
- 2010-07-30 HU HUE10739973A patent/HUE046705T2/hu unknown
- 2010-07-30 JP JP2012522244A patent/JP5708943B2/ja active Active
- 2010-07-30 RS RSP20191169 patent/RS59294B1/sr unknown
- 2010-07-30 US US13/387,791 patent/US20120135090A1/en not_active Abandoned
- 2010-07-30 CN CN2010800327206A patent/CN102548580A/zh active Pending
- 2010-07-30 AR ARP100102787A patent/AR077347A1/es not_active Application Discontinuation
- 2010-07-30 GB GB201012903A patent/GB2472324C/en active Active
- 2010-07-30 PL PL10739973T patent/PL2459218T3/pl unknown
- 2010-07-30 TW TW099125291A patent/TWI478716B/zh active
- 2010-07-30 AT AT0075910U patent/AT12341U1/de not_active IP Right Cessation
- 2010-07-30 BR BR112012001899A patent/BR112012001899B8/pt active IP Right Grant
- 2010-07-30 NL NL2005176A patent/NL2005176C2/en active
- 2010-07-30 IT ITMI2010A001436A patent/IT1402374B1/it active
-
2012
- 2012-01-26 ZA ZA2012/00661A patent/ZA201200661B/en unknown
-
2014
- 2014-01-28 US US14/166,716 patent/US9468686B2/en active Active
-
2019
- 2019-09-05 CY CY20191100931T patent/CY1122081T1/el unknown
- 2019-12-18 AR ARP190103730A patent/AR117718A2/es unknown
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