DK2459218T3 - Opløsninger med polyethylengycol og elektrolytter - Google Patents

Opløsninger med polyethylengycol og elektrolytter Download PDF

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Publication number
DK2459218T3
DK2459218T3 DK10739973.5T DK10739973T DK2459218T3 DK 2459218 T3 DK2459218 T3 DK 2459218T3 DK 10739973 T DK10739973 T DK 10739973T DK 2459218 T3 DK2459218 T3 DK 2459218T3
Authority
DK
Denmark
Prior art keywords
polyethylengycol
electrolytes
solutions
Prior art date
Application number
DK10739973.5T
Other languages
Danish (da)
English (en)
Inventor
Chris Seldon
Dawn Padfield
Frances Morrissey
Original Assignee
Norgine Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norgine Bv filed Critical Norgine Bv
Application granted granted Critical
Publication of DK2459218T3 publication Critical patent/DK2459218T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/075Ethers or acetals
    • A61K31/08Ethers or acetals acyclic, e.g. paraformaldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • A61K31/77Polymers containing oxygen of oxiranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10Carbonates; Bicarbonates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/14Alkali metal chlorides; Alkaline earth metal chlorides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
DK10739973.5T 2009-07-30 2010-07-30 Opløsninger med polyethylengycol og elektrolytter DK2459218T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0913295.2A GB0913295D0 (en) 2009-07-30 2009-07-30 Improvements in and relating to pharmaceutical compositions
PCT/GB2010/001455 WO2011012866A1 (en) 2009-07-30 2010-07-30 Solutions comprising polyethylene glycol and electrolytes

Publications (1)

Publication Number Publication Date
DK2459218T3 true DK2459218T3 (da) 2019-10-21

Family

ID=41067102

Family Applications (1)

Application Number Title Priority Date Filing Date
DK10739973.5T DK2459218T3 (da) 2009-07-30 2010-07-30 Opløsninger med polyethylengycol og elektrolytter

Country Status (32)

Country Link
US (2) US20120135090A1 (enExample)
EP (1) EP2459218B1 (enExample)
JP (1) JP5708943B2 (enExample)
KR (1) KR101868834B1 (enExample)
CN (2) CN103932979B (enExample)
AR (2) AR077347A1 (enExample)
AT (1) AT12341U1 (enExample)
AU (1) AU2010277354B2 (enExample)
BE (1) BE1019753A5 (enExample)
BR (1) BR112012001899B8 (enExample)
CA (1) CA2769247C (enExample)
CY (1) CY1122081T1 (enExample)
DK (1) DK2459218T3 (enExample)
EA (1) EA025112B1 (enExample)
ES (1) ES2388095B1 (enExample)
FR (1) FR2948569B3 (enExample)
GB (3) GB0913295D0 (enExample)
HR (1) HRP20191465T1 (enExample)
HU (1) HUE046705T2 (enExample)
IT (1) IT1402374B1 (enExample)
LT (1) LT2459218T (enExample)
MX (1) MX337114B (enExample)
NL (1) NL2005176C2 (enExample)
NZ (1) NZ597822A (enExample)
PL (1) PL2459218T3 (enExample)
PT (1) PT2459218T (enExample)
RS (1) RS59294B1 (enExample)
SI (1) SI2459218T1 (enExample)
SM (1) SMT201900569T1 (enExample)
TW (1) TWI478716B (enExample)
WO (1) WO2011012866A1 (enExample)
ZA (1) ZA201200661B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201200637D0 (en) 2012-01-13 2012-02-29 Norgine Bv Improvements in and relating to compositions
KR101852502B1 (ko) 2011-01-31 2018-04-26 노어긴 비.브이. 조성물에 관한 개선
TWI535461B (zh) 2011-03-11 2016-06-01 諾金私人有限公司 結腸清潔溶液、用於製備該溶液之組成物、包含該組成物或溶液之套組、與製備該溶液之方法
CN102600201B (zh) * 2012-02-07 2014-07-16 舒泰神(北京)生物制药股份有限公司 用于通便和清肠的药物组合物及其制备方法
US20140065076A1 (en) * 2012-08-30 2014-03-06 Otsuka Pharmaceutical Co. Ltd. Container with concentrated substance and method of using the same
NZ743984A (en) 2012-09-11 2019-10-25 Norgine Bv Compositions comprising polyethylene glycol, alkali metal or alkaline earth metal sulphates and electrolytes for use as colon cleansing compositions
JP6441890B2 (ja) 2013-03-15 2018-12-19 ブレインツリー・ラボラトリーズ,インコーポレイテッド 硫酸塩の両用経口薬学的組成物錠剤およびその使用の方法
CN112494511A (zh) * 2020-12-06 2021-03-16 天津康哲医药科技发展有限公司 一种聚乙二醇钠钾口服药物制剂的制备

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0231356A1 (en) * 1985-08-01 1987-08-12 Braintree Laboratories, Inc. Low-sodium laxative and lavage formulation
JP2596764B2 (ja) 1987-11-18 1997-04-02 ルセル森下株式会社 腸管洗浄液剤
US5378470A (en) 1989-07-25 1995-01-03 Henning Berlin Gmbh Rectally administered pharmaceutical preparation
EP0670725A1 (en) 1992-11-24 1995-09-13 Block Drug Company, Inc. Pharmaceutical compositions for use in gastrointestinal washes
RU2111741C1 (ru) * 1994-10-27 1998-05-27 Государственный научный центр колопроктологии Министерства здравоохранения и медицинской промышленности Российской Федерации Вещество для общего промывания желудочно-кишечного тракта
US5710183A (en) 1995-07-14 1998-01-20 Halow; George M. Laxative/antidiarrheal composition comprising polyethylene glycol and fiber bulking agent
US6162464A (en) 1997-03-31 2000-12-19 Inkine Pharmaceutical, Inc. Non-aqueous colonic purgative formulations
US6071523A (en) 1998-06-03 2000-06-06 Taro Pharmaceuticals Industries, Ltd. Spill resistant pharmaceutical compositions in semi-solid form
US6048901A (en) 1999-04-20 2000-04-11 Braintree Laboratories, Inc. Method of reducing intestinal gas, cramping and anorectal irritation
IL137275A0 (en) 2000-07-12 2001-07-24 Yosefus Azaria Pharmaceutical composition for the treatment of anal fissures
ATE477790T1 (de) 2001-10-29 2010-09-15 Ajinomoto Kk Lösung zur darmreinigung
US6946149B2 (en) 2002-04-30 2005-09-20 Braintree Laboratories, Inc. Salt solution for colon cleansing
US7291324B2 (en) * 2002-10-22 2007-11-06 Braintree Laboratories Inc. Method of bowel cleansing
GB0224909D0 (en) * 2002-10-25 2002-12-04 Norgine Europe Bv Colon cleansing compositions
US7332184B2 (en) 2003-03-28 2008-02-19 Queen's University At Kingston Colonic cleansing composition and method
PL1663257T3 (pl) 2003-07-09 2009-08-31 Braintree Laboratories Inc Zastosowanie środków przeczyszczających do leczenia zespołu jelita drażliwego
WO2005049049A1 (en) * 2003-11-17 2005-06-02 Braintree Laboratories, Inc. Therapeutic peg solution concentrate
GB0409104D0 (en) 2004-04-23 2004-05-26 Norgine Europe Bv Compressed pharmaceutical compositions
WO2006122104A1 (en) * 2005-05-06 2006-11-16 Salix Pharmaceuticals, Inc. Polyethylene glycol colonic purgative composition
US20070082061A1 (en) * 2005-10-07 2007-04-12 Nelson Ayala Reduction of saltiness with sweeteners
DE102006001199A1 (de) 2006-01-10 2007-07-12 Medicoforum Gmbh Fixe Kombination von Substanzen unter Beigabe von Entschäumern zum Einsatz als Darmspüllösung und/oder Laxans
ES2278537B1 (es) 2006-01-30 2008-09-16 Laboratorios Casen-Fleet, S.L. Procedimiento de fabricacion de una solucion a base de polietilenglicol con electrolitos, producto obtenido y uso.
CN1850112B (zh) * 2006-03-06 2011-06-29 北京圣永制药有限公司 聚乙二醇-电解质口服溶液
DE112008002398A5 (de) * 2007-09-22 2010-07-29 Bayer Consumer Care Ag Zusammensetzung mit Wirkstoffkombination aus einem Laxans und einem Entschäumer zur Behandlung von Obstipation
US8362083B2 (en) * 2008-01-15 2013-01-29 C.B. Fleet Company Inc. Taste-masked docusate compositions

Also Published As

Publication number Publication date
CN103932979A (zh) 2014-07-23
FR2948569B3 (fr) 2012-01-13
IT1402374B1 (it) 2013-09-04
ES2388095B1 (es) 2014-02-05
AU2010277354B2 (en) 2016-02-11
RS59294B1 (sr) 2019-10-31
SMT201900569T1 (it) 2019-11-13
BR112012001899B1 (pt) 2021-05-04
EA025112B1 (ru) 2016-11-30
EP2459218A1 (en) 2012-06-06
PT2459218T (pt) 2019-09-27
KR101868834B1 (ko) 2018-06-19
FR2948569A3 (fr) 2011-02-04
HRP20191465T1 (hr) 2019-11-15
AR077347A1 (es) 2011-08-17
GB2472324A (en) 2011-02-02
TWI478716B (zh) 2015-04-01
ZA201200661B (en) 2012-10-31
BR112012001899B8 (pt) 2021-05-25
MX2012001108A (es) 2012-06-01
CN102548580A (zh) 2012-07-04
AT12341U1 (de) 2012-04-15
US9468686B2 (en) 2016-10-18
GB201012903D0 (en) 2010-09-15
HUE046705T2 (hu) 2020-03-30
PL2459218T3 (pl) 2020-03-31
EA201200220A1 (ru) 2012-06-29
HK1150430A1 (en) 2011-12-30
CA2769247C (en) 2017-10-31
BE1019753A5 (fr) 2012-12-04
CN103932979B (zh) 2019-06-14
SI2459218T1 (sl) 2019-10-30
CY1122081T1 (el) 2020-11-25
ES2388095A8 (es) 2013-07-01
GB2472324A8 (en) 2011-02-23
GB2472324C (en) 2012-03-07
AR117718A2 (es) 2021-08-25
GB2478076A (en) 2011-08-24
TW201109021A (en) 2011-03-16
NL2005176C2 (en) 2011-05-17
JP5708943B2 (ja) 2015-04-30
CA2769247A1 (en) 2011-02-03
GB2478076B (en) 2012-06-06
GB0913295D0 (en) 2009-09-02
ITMI20101436A1 (it) 2011-01-31
NL2005176A (en) 2011-01-31
US20120135090A1 (en) 2012-05-31
LT2459218T (lt) 2019-09-25
WO2011012866A1 (en) 2011-02-03
NZ597822A (en) 2013-08-30
EP2459218B1 (en) 2019-07-17
MX337114B (es) 2016-02-12
BR112012001899A2 (pt) 2016-03-15
US20140147518A1 (en) 2014-05-29
KR20120081584A (ko) 2012-07-19
AU2010277354A1 (en) 2012-02-16
ES2388095A1 (es) 2012-10-08
GB201108383D0 (en) 2011-06-29
JP2013500322A (ja) 2013-01-07
GB2472324B (en) 2011-10-05

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