CY1122081T1 - Διαλυματα τα οποια περιλαμβανουν πολυαιθυλενογλυκολη και ηλεκτρολυτες - Google Patents

Διαλυματα τα οποια περιλαμβανουν πολυαιθυλενογλυκολη και ηλεκτρολυτες

Info

Publication number
CY1122081T1
CY1122081T1 CY20191100931T CY191100931T CY1122081T1 CY 1122081 T1 CY1122081 T1 CY 1122081T1 CY 20191100931 T CY20191100931 T CY 20191100931T CY 191100931 T CY191100931 T CY 191100931T CY 1122081 T1 CY1122081 T1 CY 1122081T1
Authority
CY
Cyprus
Prior art keywords
polyethylene glycol
solution
amount
electrolytes
solutions containing
Prior art date
Application number
CY20191100931T
Other languages
English (en)
Inventor
Chris Seldon
Dawn Padfield
Original Assignee
Norgine Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norgine Bv filed Critical Norgine Bv
Publication of CY1122081T1 publication Critical patent/CY1122081T1/el

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/075Ethers or acetals
    • A61K31/08Ethers or acetals acyclic, e.g. paraformaldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • A61K31/77Polymers containing oxygen of oxiranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10Carbonates; Bicarbonates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/14Alkali metal chlorides; Alkaline earth metal chlorides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Η εφεύρεση παρέχει ένα διάλυμα σε νερό το οποίο περιλαμβάνει τα ακόλουθα συστατικά στις ακόλουθες συγκεντρώσεις: (a) Ν x (70 έως 130) g/L πολυαιθυλενογλυκόλης (PEG) η οποία έχει ένα μέσο μοριακό βάρος από 2500 έως 4500˙ (b) Ν x (1,6 έως 4,0) g/L χλωριούχου νατρίου˙ (c) Ν x (0,2 έως 0,6) g/L χλωριούχου καλίου˙ (d) Ν x (0,6 έως 2,2) g/L όξινου ανθρακικού νατρίου˙ (e) Ν x μια ποσότητα συντηρητικού˙ (f) προαιρετικά Ν x μία ποσότητα αρωματικής ουσίας˙ και (g) προαιρετικά Ν x μία ποσότητα γλυκαντικού όπου Ν είναι στο εύρος από 2 έως 8. Το διάλυμα είναι ένα συμπύκνωμα για αραίωση. Κατά τη χρήση αραιώνεται Ν-πλάσιες φορές με νερό για να παράσχει ένα διάλυμα για χορήγηση σε ένα υποκείμενο για την αντιμετώπιση δυσκοιλιότητας ή ενσφήνωσης κοπράνων. Παρέχονται επίσης διαλύματα, κυτία, μοναδιαίες δόσεις και μέθοδοι που περιλαμβάνουν ή χρησιμοποιούν τα διαλύματα.
CY20191100931T 2009-07-30 2019-09-05 Διαλυματα τα οποια περιλαμβανουν πολυαιθυλενογλυκολη και ηλεκτρολυτες CY1122081T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0913295.2A GB0913295D0 (en) 2009-07-30 2009-07-30 Improvements in and relating to pharmaceutical compositions
PCT/GB2010/001455 WO2011012866A1 (en) 2009-07-30 2010-07-30 Solutions comprising polyethylene glycol and electrolytes

Publications (1)

Publication Number Publication Date
CY1122081T1 true CY1122081T1 (el) 2020-11-25

Family

ID=41067102

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20191100931T CY1122081T1 (el) 2009-07-30 2019-09-05 Διαλυματα τα οποια περιλαμβανουν πολυαιθυλενογλυκολη και ηλεκτρολυτες

Country Status (32)

Country Link
US (2) US20120135090A1 (el)
EP (1) EP2459218B1 (el)
JP (1) JP5708943B2 (el)
KR (1) KR101868834B1 (el)
CN (2) CN103932979B (el)
AR (2) AR077347A1 (el)
AT (1) AT12341U1 (el)
AU (1) AU2010277354B2 (el)
BE (1) BE1019753A5 (el)
BR (1) BR112012001899B8 (el)
CA (1) CA2769247C (el)
CY (1) CY1122081T1 (el)
DK (1) DK2459218T3 (el)
EA (1) EA025112B1 (el)
ES (1) ES2388095B1 (el)
FR (1) FR2948569B3 (el)
GB (3) GB0913295D0 (el)
HK (1) HK1150430A1 (el)
HR (1) HRP20191465T1 (el)
HU (1) HUE046705T2 (el)
IT (1) IT1402374B1 (el)
LT (1) LT2459218T (el)
MX (1) MX337114B (el)
NL (1) NL2005176C2 (el)
NZ (1) NZ597822A (el)
PL (1) PL2459218T3 (el)
PT (1) PT2459218T (el)
RS (1) RS59294B1 (el)
SI (1) SI2459218T1 (el)
TW (1) TWI478716B (el)
WO (1) WO2011012866A1 (el)
ZA (1) ZA201200661B (el)

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GB201200637D0 (en) 2012-01-13 2012-02-29 Norgine Bv Improvements in and relating to compositions
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CN102600201B (zh) * 2012-02-07 2014-07-16 舒泰神(北京)生物制药股份有限公司 用于通便和清肠的药物组合物及其制备方法
US20140065076A1 (en) * 2012-08-30 2014-03-06 Otsuka Pharmaceutical Co. Ltd. Container with concentrated substance and method of using the same
KR20170098980A (ko) 2012-09-11 2017-08-30 노어긴 비.브이. Peg 및 아스코르베이트를 포함하는 조성물
EA201992382A3 (ru) 2013-03-15 2020-05-31 Брейнтри Лабораторис, Инк. Пероральная таблетированная фармацевтическая композиция двойного применения на основе сульфатных солей и способы ее применения
CN112494511A (zh) * 2020-12-06 2021-03-16 天津康哲医药科技发展有限公司 一种聚乙二醇钠钾口服药物制剂的制备

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Also Published As

Publication number Publication date
ZA201200661B (en) 2012-10-31
JP2013500322A (ja) 2013-01-07
BR112012001899B1 (pt) 2021-05-04
EP2459218A1 (en) 2012-06-06
AR117718A2 (es) 2021-08-25
LT2459218T (lt) 2019-09-25
GB2472324A (en) 2011-02-02
US20140147518A1 (en) 2014-05-29
PL2459218T3 (pl) 2020-03-31
RS59294B1 (sr) 2019-10-31
CA2769247C (en) 2017-10-31
FR2948569B3 (fr) 2012-01-13
CN103932979A (zh) 2014-07-23
KR20120081584A (ko) 2012-07-19
TWI478716B (zh) 2015-04-01
ITMI20101436A1 (it) 2011-01-31
FR2948569A3 (fr) 2011-02-04
GB201108383D0 (en) 2011-06-29
GB2472324A8 (en) 2011-02-23
GB2478076A (en) 2011-08-24
CA2769247A1 (en) 2011-02-03
EP2459218B1 (en) 2019-07-17
AU2010277354A1 (en) 2012-02-16
CN103932979B (zh) 2019-06-14
BR112012001899A2 (pt) 2016-03-15
BE1019753A5 (fr) 2012-12-04
ES2388095A1 (es) 2012-10-08
CN102548580A (zh) 2012-07-04
US9468686B2 (en) 2016-10-18
JP5708943B2 (ja) 2015-04-30
AT12341U1 (de) 2012-04-15
US20120135090A1 (en) 2012-05-31
GB2472324B (en) 2011-10-05
EA201200220A1 (ru) 2012-06-29
GB201012903D0 (en) 2010-09-15
KR101868834B1 (ko) 2018-06-19
GB2472324C (en) 2012-03-07
NZ597822A (en) 2013-08-30
MX337114B (es) 2016-02-12
TW201109021A (en) 2011-03-16
EA025112B1 (ru) 2016-11-30
SI2459218T1 (sl) 2019-10-30
WO2011012866A1 (en) 2011-02-03
IT1402374B1 (it) 2013-09-04
GB0913295D0 (en) 2009-09-02
ES2388095A8 (es) 2013-07-01
DK2459218T3 (da) 2019-10-21
PT2459218T (pt) 2019-09-27
AR077347A1 (es) 2011-08-17
GB2478076B (en) 2012-06-06
NL2005176C2 (en) 2011-05-17
BR112012001899B8 (pt) 2021-05-25
HK1150430A1 (en) 2011-12-30
ES2388095B1 (es) 2014-02-05
HUE046705T2 (hu) 2020-03-30
MX2012001108A (es) 2012-06-01
HRP20191465T1 (hr) 2019-11-15
AU2010277354B2 (en) 2016-02-11
NL2005176A (en) 2011-01-31

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