JP2012522736A5 - - Google Patents

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Publication number
JP2012522736A5
JP2012522736A5 JP2012502514A JP2012502514A JP2012522736A5 JP 2012522736 A5 JP2012522736 A5 JP 2012522736A5 JP 2012502514 A JP2012502514 A JP 2012502514A JP 2012502514 A JP2012502514 A JP 2012502514A JP 2012522736 A5 JP2012522736 A5 JP 2012522736A5
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JP
Japan
Prior art keywords
chromatography
anion exchange
exchange chromatography
fsh
hydrophobic interaction
Prior art date
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Application number
JP2012502514A
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English (en)
Japanese (ja)
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JP5845170B2 (ja
JP2012522736A (ja
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Publication date
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Priority claimed from PCT/EP2010/002111 external-priority patent/WO2010115586A2/en
Publication of JP2012522736A publication Critical patent/JP2012522736A/ja
Publication of JP2012522736A5 publication Critical patent/JP2012522736A5/ja
Application granted granted Critical
Publication of JP5845170B2 publication Critical patent/JP5845170B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2012502514A 2009-04-01 2010-04-01 組換えｆｓｈを精製する方法 Expired - Fee Related JP5845170B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09157133 2009-04-01
EP09157133.1 2009-04-01
PCT/EP2010/002111 WO2010115586A2 (en) 2009-04-01 2010-04-01 Method for purifying recombinant fsh

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015177674A Division JP6231056B2 (ja) 2009-04-01 2015-09-09 組換えｆｓｈを精製する方法

Publications (3)

Publication Number Publication Date
JP2012522736A JP2012522736A (ja) 2012-09-27
JP2012522736A5 true JP2012522736A5 (https=) 2013-05-09
JP5845170B2 JP5845170B2 (ja) 2016-01-20

Family

ID=42153744

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2012502514A Expired - Fee Related JP5845170B2 (ja) 2009-04-01 2010-04-01 組換えｆｓｈを精製する方法
JP2015177674A Expired - Fee Related JP6231056B2 (ja) 2009-04-01 2015-09-09 組換えｆｓｈを精製する方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2015177674A Expired - Fee Related JP6231056B2 (ja) 2009-04-01 2015-09-09 組換えｆｓｈを精製する方法

Country Status (26)

Country Link
US (3) US9096683B2 (https=)
EP (1) EP2414380B1 (https=)
JP (2) JP5845170B2 (https=)
KR (1) KR101761168B1 (https=)
CN (1) CN102448979B (https=)
AU (1) AU2010234028B2 (https=)
BR (1) BRPI1012647B1 (https=)
CA (1) CA2755927A1 (https=)
CY (1) CY1116963T1 (https=)
DK (1) DK2414380T3 (https=)
EA (1) EA028065B1 (https=)
ES (1) ES2552055T3 (https=)
HR (1) HRP20151086T1 (https=)
HU (1) HUE025959T2 (https=)
IL (1) IL215234A (https=)
ME (1) ME02277B (https=)
MX (1) MX2011010480A (https=)
NZ (1) NZ595661A (https=)
PL (1) PL2414380T3 (https=)
PT (1) PT2414380E (https=)
RS (1) RS54318B1 (https=)
SI (1) SI2414380T1 (https=)
SM (1) SMT201500276B (https=)
UA (1) UA106369C2 (https=)
WO (1) WO2010115586A2 (https=)
ZA (1) ZA201106800B (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5845170B2 (ja) * 2009-04-01 2016-01-20 ラティオファーム ゲーエムベーハー 組換えｆｓｈを精製する方法
CN103570820B (zh) * 2012-08-06 2015-11-18 齐鲁制药有限公司 一种重组人促卵泡激素的纯化方法
KR101516054B1 (ko) * 2012-11-21 2015-05-06 씨제이헬스케어 주식회사 신규한 지속형 인간 성장호르몬 단량체를 제조하는 방법
CN103059125B (zh) * 2012-12-27 2015-08-12 浙江海正药业股份有限公司 重组人促卵泡激素的纯化方法
EP2968391A1 (en) 2013-03-13 2016-01-20 Moderna Therapeutics, Inc. Long-lived polynucleotide molecules
CN103539860B (zh) * 2013-11-01 2014-12-03 广州优联康医药科技有限公司 一种长效重组人促卵泡激素融合蛋白
CN103539861B (zh) * 2013-11-01 2015-02-18 广州联康生物科技有限公司 长效重组人促卵泡激素融合蛋白
KR20160131113A (ko) * 2014-04-18 2016-11-15 카딜라 핼쓰캐어 리미티드 고나도트로핀의 신규한 정제 방법
CN104479005B (zh) * 2014-09-05 2017-10-31 上海丽珠制药有限公司 一种促性腺激素纯化的方法
CN105461799A (zh) * 2015-12-31 2016-04-06 哈药集团技术中心 一种重组人促卵泡生成素的纯化方法
CN106117342B (zh) * 2016-07-07 2020-01-03 江西浩然生物医药有限公司 一种高纯度尿促卵泡素的制备方法
RU2694598C1 (ru) * 2018-08-07 2019-07-16 Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) Клеточная линия huFSHKKc6 - продуцент рекомбинантного человеческого фолликулостимулирующего гормона (ФСГ) и способ получения ФСГ с использованием данной линии
CN114867741A (zh) * 2019-12-26 2022-08-05 株式会社Lg化学 纯化促卵泡激素的方法
KR102283871B1 (ko) * 2021-03-02 2021-08-02 한국원자력연구원 크로마토그래피를 이용한 무담체 홀뮴-166의 분리 방법, 분리 장치 및 이에 의하여 분리된 무담체 홀뮴-166
CN113372433B (zh) * 2021-03-12 2022-10-11 上海景泽生物技术有限公司 纯化fsh方法
CN114591414A (zh) * 2022-03-24 2022-06-07 江西浩然生物制药有限公司 一种人绒毛膜促性腺激素的制备方法

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US4923805A (en) 1983-11-02 1990-05-08 Integrated Genetics, Inc. Fsh
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US6455282B1 (en) * 1983-11-02 2002-09-24 Genzyme Corporation Cells, vectors and methods for producing biologically active TSH
IT1206302B (it) 1987-06-26 1989-04-14 Serono Cesare Ist Ricerca Ormone follicolo-stimolante urinario
CA2018676C (en) 1989-06-20 2003-05-06 Christie A. Kelton Novel heteropolymeric protein production methods
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ES2572629T3 (es) * 2005-12-09 2016-06-01 Ares Trading S.A. Método para purificar FSH o un mutante de FSH
EP1960419B1 (en) 2005-12-09 2016-03-16 Ares Trading S.A. Method for purifying fsh or a fsh mutant
DK2170942T3 (da) * 2007-06-28 2013-11-04 Biogenerix Ag Fsh-producerende celleklon
AR067536A1 (es) * 2007-07-17 2009-10-14 Hoffmann La Roche Metodo para obtener una eritropoyetina mono-pegilada en una forma sustancialmente homogenea
JP5845170B2 (ja) * 2009-04-01 2016-01-20 ラティオファーム ゲーエムベーハー 組換えｆｓｈを精製する方法

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