JP2014520142A5 - - Google Patents
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- Publication number
- JP2014520142A5 JP2014520142A5 JP2014516487A JP2014516487A JP2014520142A5 JP 2014520142 A5 JP2014520142 A5 JP 2014520142A5 JP 2014516487 A JP2014516487 A JP 2014516487A JP 2014516487 A JP2014516487 A JP 2014516487A JP 2014520142 A5 JP2014520142 A5 JP 2014520142A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- ischemia
- composition according
- inhibitor
- reperfusion therapy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161501117P | 2011-06-24 | 2011-06-24 | |
| US61/501,117 | 2011-06-24 | ||
| US201261617001P | 2012-03-28 | 2012-03-28 | |
| US61/617,001 | 2012-03-28 | ||
| PCT/IB2012/053178 WO2012176172A2 (en) | 2011-06-24 | 2012-06-23 | Combination therapy for ischemia |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017074975A Division JP2017193535A (ja) | 2011-06-24 | 2017-04-05 | 虚血のための組み合わせ療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014520142A JP2014520142A (ja) | 2014-08-21 |
| JP2014520142A5 true JP2014520142A5 (https=) | 2015-08-06 |
| JP6401057B2 JP6401057B2 (ja) | 2018-10-03 |
Family
ID=47423033
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014516487A Expired - Fee Related JP6401057B2 (ja) | 2011-06-24 | 2012-06-23 | 虚血のための組み合わせ療法 |
| JP2017074975A Pending JP2017193535A (ja) | 2011-06-24 | 2017-04-05 | 虚血のための組み合わせ療法 |
| JP2018204034A Expired - Fee Related JP7085457B2 (ja) | 2011-06-24 | 2018-10-30 | 虚血のための組み合わせ療法 |
| JP2020134150A Active JP7143374B2 (ja) | 2011-06-24 | 2020-08-06 | 虚血のための組み合わせ療法 |
| JP2022146191A Pending JP2022188068A (ja) | 2011-06-24 | 2022-09-14 | 虚血のための組み合わせ療法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017074975A Pending JP2017193535A (ja) | 2011-06-24 | 2017-04-05 | 虚血のための組み合わせ療法 |
| JP2018204034A Expired - Fee Related JP7085457B2 (ja) | 2011-06-24 | 2018-10-30 | 虚血のための組み合わせ療法 |
| JP2020134150A Active JP7143374B2 (ja) | 2011-06-24 | 2020-08-06 | 虚血のための組み合わせ療法 |
| JP2022146191A Pending JP2022188068A (ja) | 2011-06-24 | 2022-09-14 | 虚血のための組み合わせ療法 |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US10064910B2 (https=) |
| EP (3) | EP2723363B1 (https=) |
| JP (5) | JP6401057B2 (https=) |
| KR (5) | KR102296106B1 (https=) |
| CN (1) | CN103648518B (https=) |
| AU (1) | AU2012274910B2 (https=) |
| CA (1) | CA2839630A1 (https=) |
| CY (1) | CY1121379T1 (https=) |
| DK (2) | DK2723363T3 (https=) |
| ES (2) | ES2912042T3 (https=) |
| HR (2) | HRP20220519T1 (https=) |
| HU (2) | HUE058238T2 (https=) |
| LT (1) | LT2723363T (https=) |
| PL (2) | PL3427748T3 (https=) |
| PT (2) | PT2723363T (https=) |
| RS (1) | RS57798B1 (https=) |
| SI (1) | SI2723363T1 (https=) |
| SM (1) | SMT201800592T1 (https=) |
| WO (1) | WO2012176172A2 (https=) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2440230T (pt) | 2009-06-10 | 2021-02-03 | Nono Inc | Regimes de tratamento para tratamento de doenças neurológicas |
| EP2723363B1 (en) | 2011-06-24 | 2018-08-29 | NoNO Inc. | Combination therapy for ischemia |
| US9241970B2 (en) | 2011-12-13 | 2016-01-26 | Nono Inc. | Therapy for subarachnoid hemorrhage and ischemia |
| CZ2012476A3 (cs) * | 2012-07-12 | 2014-01-22 | Ústav organické chemie a biochemie Akademie věd ČR, v. v. i. | Lipidované peptidy jako antiobezitika |
| WO2015023830A1 (en) * | 2013-08-14 | 2015-02-19 | Stc.Unm | Treatment and prevention of stroke and other neurological disorders |
| US20170165317A1 (en) * | 2013-11-26 | 2017-06-15 | Trustees Of Dartmouth College | Method for mitigating or alleviating synaptic and cognitive deficits |
| FR3021319B1 (fr) * | 2014-05-22 | 2018-08-31 | Sederma | Peptides, compositions les comprenant et utilisations notamment cosmetiques |
| CZ309217B6 (cs) * | 2014-05-27 | 2022-06-01 | Ústav Organické Chemie A Biochemie Av Čr, V.V.I. | Lipidované peptidy jako neuroprotektiva |
| CN106661126B (zh) * | 2014-05-28 | 2021-12-10 | 诺诺公司 | TAT-NR2B9c的氯盐 |
| US9526768B2 (en) | 2014-11-13 | 2016-12-27 | Jennifer Mai | Compositions for the treatment of cancer |
| CN104497106B (zh) * | 2014-12-05 | 2017-05-10 | 华中科技大学 | 一种小分子多肽、其应用及产品 |
| KR102253900B1 (ko) * | 2016-04-27 | 2021-05-18 | 바이오셀즈(베이징) 바이오테크 코., 엘티디. | 흥분성 신경독성 관련 손상 치료용 펩타이드 |
| JP2019522675A (ja) * | 2016-04-27 | 2019-08-15 | ▲拝▼西欧斯（北京）生物技▲術▼有限公司 | 興奮製神経毒性に関連した損傷の治療方法 |
| CN107312069B (zh) * | 2016-04-27 | 2018-11-06 | 拜西欧斯（北京）生物技术有限公司 | 兴奋性神经毒性相关损伤的治疗肽 |
| CN107446016A (zh) * | 2016-05-30 | 2017-12-08 | 上海交通大学 | 一种硬脂酸修饰的细胞穿膜肽及其制备与应用 |
| CN106265594B (zh) * | 2016-09-21 | 2019-07-26 | 南京医科大学 | 一种缺血性脑卒中靶向的红细胞膜仿生智能药物载体及其制备方法 |
| CN106749559B (zh) * | 2016-11-23 | 2020-09-04 | 郑州大学 | 一种基于细胞穿膜肽Tat(49-57)的抗菌肽及其合成方法 |
| JP7109958B2 (ja) * | 2017-04-04 | 2022-08-01 | キヤノンメディカルシステムズ株式会社 | 磁気共鳴イメージングシステム、磁気共鳴イメージング装置、及び磁気共鳴イメージング方法 |
| BR112020000115A2 (pt) * | 2017-07-05 | 2020-07-07 | Biocells (Beijing) Biotech Co., Ltd. | sais farmaceuticamente aceitáveis de polipeptídeos e uso dos mesmos |
| WO2019006691A1 (zh) * | 2017-07-05 | 2019-01-10 | 拜西欧斯（北京）生物技术有限公司 | 用于治疗、改善或预防脑出血的肽及其用途 |
| JP7073486B2 (ja) * | 2017-09-30 | 2022-05-23 | ▲拝▼西欧斯（北京）生物技▲術▼有限公司 | 興奮性神経毒性に関連した損傷の治療用ペプチド組成物 |
| WO2019195741A1 (en) * | 2018-04-06 | 2019-10-10 | Northwestern University | Bdnf mimetic peptide amphiphiles |
| JP7158904B2 (ja) * | 2018-06-14 | 2022-10-24 | 社会福祉法人 恩賜財団済生会熊本病院 | 治療方針決定支援装置、治療方針決定支援装置の作動方法、および治療方針決定支援プログラム |
| US12285182B2 (en) | 2018-10-10 | 2025-04-29 | Innova Vascular, Inc. | Devices and methods for removing an embolus |
| JP2023511057A (ja) * | 2020-01-09 | 2023-03-16 | ノノ インコーポレイテッド | 脳卒中及び関連疾患を治療するためのプラスミン耐性ペプチド |
| CA3170425A1 (en) * | 2020-02-19 | 2021-08-26 | Nono Inc. | Inhibition of reperfusion injury with a psd-95 inhibitor |
| IL295727A (en) * | 2020-02-19 | 2022-10-01 | Nono Inc | Combined treatment of stroke with a plasmin-degradable and reperfusion psd-95 inhibitor |
| CN113735938B (zh) * | 2021-07-30 | 2024-11-08 | 英纳氏(珠海)药业有限公司 | 一种神经保护多肽化合物及其应用 |
| WO2023192848A1 (en) * | 2022-03-28 | 2023-10-05 | University Of Maryland, Baltimore | Methods and compositions for the treatment of stroke |
| WO2024149230A1 (zh) | 2023-01-09 | 2024-07-18 | 北京拓界生物医药科技有限公司 | 一种神经保护性psd-95多肽抑制剂及其应用 |
| CN117422722B (zh) * | 2023-12-19 | 2024-03-29 | 北京智源人工智能研究院 | 基于adc图像的肿瘤预后特征评估的方法和装置 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2742152B1 (fr) | 1995-12-06 | 1998-01-16 | Synthelabo | Derives de 5-naphtalen-1-yl-1,3-dioxanes, leur preparation et leur application en therapeutique |
| US6562345B1 (en) | 1996-11-12 | 2003-05-13 | City Of Hope | Immuno-reactive peptide CTL epitopes of human cytomegalovirus |
| US6903184B1 (en) | 1998-03-02 | 2005-06-07 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Multiple antigenic peptides immunogenic against Streptococcus pneumonia |
| US20060148711A1 (en) | 1999-05-14 | 2006-07-06 | Arbor Vita Corporation | Molecular interactions in neurons |
| US7510824B2 (en) | 1999-06-02 | 2009-03-31 | Nono Inc. | Method of screening peptides useful in treating traumatic injury to the brain or spinal cord |
| GB0025473D0 (en) * | 2000-10-17 | 2000-11-29 | Pfizer Ltd | Pharmaceutical combinations |
| AU2004233862A1 (en) | 2003-04-25 | 2004-11-11 | Mitos Pharmaceuticals, Inc. | Prophylactic pretreatment with antioxidants |
| EP1622639B1 (de) * | 2003-05-02 | 2013-01-16 | Lundbeck, H., A/S | Intravenöse injektion nicht-neurotoxischer plasminogen-aktivatoren zur behandlung von schlaganfall |
| BRPI0410470A (pt) * | 2003-05-19 | 2006-06-20 | Kenneth S Warren Inst Inc | uso de uma eritropoietina ou de uma citocina protetora de tecido e método para proteger ou manter a viabilidade de uma célula, tecido ou órgão de mamìfero respondente |
| TWI395591B (zh) | 2004-04-01 | 2013-05-11 | Oncothyreon Inc | 黏液性糖蛋白（ｍｕｃ-１）疫苗 |
| WO2008008348A2 (en) | 2006-07-11 | 2008-01-17 | Arbor Vita Corporation | Method and compositions for treating stroke with fever |
| EP1884521A1 (en) | 2006-07-31 | 2008-02-06 | Xigen S.A. | Fusion peptide for inhibiting interaction of neuronal NMDA receptor (NMDAR) and NMDAR interacting proteins |
| CU23630A1 (es) | 2006-10-30 | 2011-02-24 | Ct Ingenieria Genetica Biotech | Moléculas peptídicas quiméricas con propiedades antivirales contra los virus de la familia flaviviridae |
| DK2120987T3 (en) * | 2007-03-02 | 2014-02-24 | Nono Inc | Treatment of stroke and other diseases without inhibiting N-type calcium channels |
| GB0707348D0 (en) | 2007-04-17 | 2007-05-23 | Renovo Ltd | Medicaments and methods for inhibition of scarring |
| WO2009006611A1 (en) | 2007-07-03 | 2009-01-08 | Arbor Vita Corporation | Small molecule inhibitors of pdz interactions |
| CA2701420C (en) | 2007-10-29 | 2016-02-09 | Helix Biomedix Inc. | Protective skin care tetrapeptides |
| US8080518B2 (en) | 2007-12-05 | 2011-12-20 | Arbor Vita Corporation | Co-administration of an agent linked to an internalization peptide with an anti-inflammatory |
| KR101720760B1 (ko) | 2008-01-25 | 2017-03-28 | 오르후스 우니베르시테트 | Ｉｇｆｂｐ-4에 대한 ｐａｐｐ-ａ 활성의 선택적 엑소사이트 억제 |
| WO2010004003A2 (en) | 2008-07-09 | 2010-01-14 | University Of Copenhagen | Modified peptides as potent inhibitors of the psd-95/nmda receptor interaction |
| DE102008037564A1 (de) | 2008-11-19 | 2010-05-20 | Forschungszentrum Jülich GmbH | Zusammensetzung zur Herstellung von anti-Amyloid beta-Peptid-Antikörpern mit D-Peptiden |
| CA2665302A1 (en) | 2009-05-01 | 2010-11-01 | Universite De Montreal | Cd36 modulation and uses thereof |
| PT2440230T (pt) | 2009-06-10 | 2021-02-03 | Nono Inc | Regimes de tratamento para tratamento de doenças neurológicas |
| CA3018494C (en) | 2009-06-10 | 2021-12-07 | Nono Inc. | Co-administration of an agent linked to an internalization peptide with an anti-inflammatory |
| US20110144029A1 (en) | 2009-09-30 | 2011-06-16 | Board Of Regents, The University Of Texas System | Model Systems and Materials for the Study and Treatment of Neurodegenerative Diseases |
| EP2723363B1 (en) | 2011-06-24 | 2018-08-29 | NoNO Inc. | Combination therapy for ischemia |
| US9241970B2 (en) | 2011-12-13 | 2016-01-26 | Nono Inc. | Therapy for subarachnoid hemorrhage and ischemia |
| JP6279483B2 (ja) | 2011-12-13 | 2018-02-14 | ノノ インコーポレイテッド | くも膜下出血および虚血の治療法 |
-
2012
- 2012-06-23 EP EP12802409.8A patent/EP2723363B1/en active Active
- 2012-06-23 KR KR1020207021829A patent/KR102296106B1/ko not_active Expired - Fee Related
- 2012-06-23 PL PL18190827T patent/PL3427748T3/pl unknown
- 2012-06-23 ES ES18190827T patent/ES2912042T3/es active Active
- 2012-06-23 AU AU2012274910A patent/AU2012274910B2/en not_active Ceased
- 2012-06-23 KR KR1020197026571A patent/KR102140169B1/ko not_active Expired - Fee Related
- 2012-06-23 PT PT12802409T patent/PT2723363T/pt unknown
- 2012-06-23 HR HRP20220519TT patent/HRP20220519T1/hr unknown
- 2012-06-23 HU HUE18190827A patent/HUE058238T2/hu unknown
- 2012-06-23 US US14/128,941 patent/US10064910B2/en active Active
- 2012-06-23 EP EP22157256.3A patent/EP4052721A1/en not_active Withdrawn
- 2012-06-23 PT PT181908278T patent/PT3427748T/pt unknown
- 2012-06-23 KR KR1020227025470A patent/KR20220106862A/ko active Pending
- 2012-06-23 EP EP18190827.8A patent/EP3427748B1/en active Active
- 2012-06-23 LT LTEP12802409.8T patent/LT2723363T/lt unknown
- 2012-06-23 PL PL12802409T patent/PL2723363T3/pl unknown
- 2012-06-23 RS RS20181182A patent/RS57798B1/sr unknown
- 2012-06-23 CA CA2839630A patent/CA2839630A1/en active Pending
- 2012-06-23 HR HRP20181526TT patent/HRP20181526T1/hr unknown
- 2012-06-23 HU HUE12802409A patent/HUE040564T2/hu unknown
- 2012-06-23 WO PCT/IB2012/053178 patent/WO2012176172A2/en not_active Ceased
- 2012-06-23 ES ES12802409.8T patent/ES2690994T3/es active Active
- 2012-06-23 KR KR1020147001639A patent/KR102022116B1/ko not_active Expired - Fee Related
- 2012-06-23 KR KR1020217026955A patent/KR102425466B1/ko not_active Expired - Fee Related
- 2012-06-23 DK DK12802409.8T patent/DK2723363T3/en active
- 2012-06-23 SM SM20180592T patent/SMT201800592T1/it unknown
- 2012-06-23 DK DK18190827.8T patent/DK3427748T3/da active
- 2012-06-23 CN CN201280031302.4A patent/CN103648518B/zh not_active Expired - Fee Related
- 2012-06-23 SI SI201231412T patent/SI2723363T1/sl unknown
- 2012-06-23 JP JP2014516487A patent/JP6401057B2/ja not_active Expired - Fee Related
-
2017
- 2017-04-05 JP JP2017074975A patent/JP2017193535A/ja active Pending
-
2018
- 2018-08-01 US US16/051,971 patent/US10967041B2/en not_active Expired - Fee Related
- 2018-10-30 JP JP2018204034A patent/JP7085457B2/ja not_active Expired - Fee Related
- 2018-11-28 CY CY20181101260T patent/CY1121379T1/el unknown
-
2020
- 2020-08-06 JP JP2020134150A patent/JP7143374B2/ja active Active
-
2021
- 2021-02-17 US US17/177,970 patent/US11878044B2/en active Active
-
2022
- 2022-09-14 JP JP2022146191A patent/JP2022188068A/ja active Pending
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