JP2009527226A5 - - Google Patents

Info

Publication number

JP2009527226A5

JP2009527226A5 JP2008555421A JP2008555421A JP2009527226A5 JP 2009527226 A5 JP2009527226 A5 JP 2009527226A5 JP 2008555421 A JP2008555421 A JP 2008555421A JP 2008555421 A JP2008555421 A JP 2008555421A JP 2009527226 A5 JP2009527226 A5 JP 2009527226A5

Authority

JP

Japan

Prior art keywords

chimeric protein

polypeptide

host cell

seq

fragment

Prior art date

2007-02-16

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
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• 102000037865 fusion proteins Human genes 0.000 claims 17
• 108020001507 fusion proteins Proteins 0.000 claims 17
• 229920001184 polypeptide Polymers 0.000 claims 7
• 102000004196 processed proteins & peptides Human genes 0.000 claims 7
• 108090000765 processed proteins & peptides Proteins 0.000 claims 7
• 239000012634 fragment Substances 0.000 claims 4
• 238000012986 modification Methods 0.000 claims 4
• 230000004048 modification Effects 0.000 claims 4
• 102000039446 nucleic acids Human genes 0.000 claims 4
• 108020004707 nucleic acids Proteins 0.000 claims 4
• 150000007523 nucleic acids Chemical class 0.000 claims 4
• 125000003275 alpha amino acid group Chemical group 0.000 claims 3
• 238000000034 method Methods 0.000 claims 3
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
• 206010012735 Diarrhoea Diseases 0.000 claims 2
• 208000032759 Hemolytic-Uremic Syndrome Diseases 0.000 claims 2
• 241000282412 Homo Species 0.000 claims 2
• 241000124008 Mammalia Species 0.000 claims 2
• 108010079723 Shiga Toxin Proteins 0.000 claims 2
• 238000004519 manufacturing process Methods 0.000 claims 2
• 241000588724 Escherichia coli Species 0.000 claims 1
• 238000012258 culturing Methods 0.000 claims 1
• 208000015181 infectious disease Diseases 0.000 claims 1
• 102000004169 proteins and genes Human genes 0.000 claims 1
• 108090000623 proteins and genes Proteins 0.000 claims 1